Rapid hydrolysis and slow α,β-dicarbonyl cleavage of an agent proposed to cleave glucose-derived protein cross-links

Biochemical Pharmacology

Volumn 57, Issue 3, 1999, Pages 303-307

  Thornalley, Paul J ^a   Minhas, Harjit S ^a  

^a UNIVERSITY OF ESSEX   (United Kingdom)

Author keywords

, dicarbonyl; Advanced glycation end products; Aminoguanidine; Glycation; Nonsulphydryl cross link; Thiazolium

Indexed keywords

AMINOGUANIDINE; N PHENACYLTHIAZOLIUM BROMIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; GLYCATION; HYDROLYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PRIORITY JOURNAL; PROTEIN CROSS LINKING;

CROSS-LINKING REAGENTS; GLYCOSYLATION; GLYCOSYLATION END PRODUCTS, ADVANCED; HYDROLYSIS; MOLECULAR STRUCTURE; THIAZOLES; TIME FACTORS;

EID: 0032944619     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00284-6     Document Type: Article

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