New oxidovanadium(IV) N-acylhydrazone complexes: Promising antileishmanial and antitrypanosomal agents

European Journal of Medicinal Chemistry

Volumn 62, Issue , 2013, Pages 20-27

  Benítez, Julio ^a   Cavalcanti De Queiroz, Aline ^b   Correia, Isabel ^c   Alves, Marina Amaral ^d   Alexandre Moreira, Magna S ^b   Barreiro, Eliezer J ^d   Lima, Lidia Moreira ^d   Varela, Javier ^e   González, Mercedes ^e   Cerecetto, Hugo ^e   Moreno, Virtudes ^f   Pessoa, João Costa ^c   Gambino, Dinorah ^a  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b FEDERAL UNIVERSITY OF ALAGOAS   (Brazil)

^c INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^d FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^e UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^f UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Chagas disease; Heteroleptic complexes; Leishmaniasis; N Acylhydrazones; Oxidovanadium(IV) compounds; Oxidovanadium(IV) phenanthroline complexes

Indexed keywords

1,10 PHENANTHROLINE; ANTILEISHMANIAL AGENT; ANTITRYPANOSOMAL AGENT; N (2 HYDROXYBENZYLIDENE 4 CHLOROBENZOHYDRAZIDE; N ACYLHYDRAZONE; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; CYTOTOXICITY; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; EPIMASTIGOTE; FLUORESCENCE SPECTROSCOPY; IN VITRO STUDY; INFRARED SPECTROSCOPY; LEISHMANIA MAJOR; MACROPHAGE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TRYPANOSOMA CRUZI; VISCOMETRY;

ANIMALS; ANTIPARASITIC AGENTS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDRAZONES; LEISHMANIA; MACROPHAGES; MICE; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; PARASITIC SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA CRUZI; VANADIUM;

EID: 84872677854     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.12.036     Document Type: Article

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