-
1
-
-
34249949338
-
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
-
C. Amador-Ortiz, W.L. Lin, Z. Ahmed, D. Personett, P. Davies, R. Duara, N.R. Graff-Radford, M.L. Hutton, and D.W. Dickson TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease Ann. Neurol. 61 2007 435 445
-
(2007)
Ann. Neurol.
, vol.61
, pp. 435-445
-
-
Amador-Ortiz, C.1
Lin, W.L.2
Ahmed, Z.3
Personett, D.4
Davies, P.5
Duara, R.6
Graff-Radford, N.R.7
Hutton, M.L.8
Dickson, D.W.9
-
2
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
T. Arai, M. Hasegawa, H. Akiyama, K. Ikeda, T. Nonaka, H. Mori, D. Mann, K. Tsuchiya, M. Yoshida, Y. Hashizume, and T. Oda TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Biochem. Biophys. Res. Commun. 351 2006 602 611
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
Ikeda, K.4
Nonaka, T.5
Mori, H.6
Mann, D.7
Tsuchiya, K.8
Yoshida, M.9
Hashizume, Y.10
Oda, T.11
-
3
-
-
38449102667
-
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease
-
E. Buratti, and F.E. Baralle Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease Front. Biosci. 13 2008 867 878
-
(2008)
Front. Biosci.
, vol.13
, pp. 867-878
-
-
Buratti, E.1
Baralle, F.E.2
-
4
-
-
70349301708
-
The histopathology of gastrointestinal motility disorders in children
-
S. Feichter, W.A. Meier-Ruge, and E. Bruder The histopathology of gastrointestinal motility disorders in children Semin. Pediatr. Surg. 18 2009 206 211
-
(2009)
Semin. Pediatr. Surg.
, vol.18
, pp. 206-211
-
-
Feichter, S.1
Meier-Ruge, W.A.2
Bruder, E.3
-
5
-
-
34249679116
-
P62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis
-
J. Gal, A.L. Strom, R. Kilty, F. Zhang, and H. Zhu p62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis J. Biol. Chem. 282 2007 11068 11077
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 11068-11077
-
-
Gal, J.1
Strom, A.L.2
Kilty, R.3
Zhang, F.4
Zhu, H.5
-
6
-
-
36949036676
-
Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam
-
F. Geser, M.J. Winton, L.K. Kwong, Y. Xu, S.X. Xie, L.M. Igaz, R.M. Garruto, D.P. Perl, D. Galasko, V.M. Lee, and J.Q. Trojanowski Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam Acta Neuropathol. 115 2008 133 145
-
(2008)
Acta Neuropathol.
, vol.115
, pp. 133-145
-
-
Geser, F.1
Winton, M.J.2
Kwong, L.K.3
Xu, Y.4
Xie, S.X.5
Igaz, L.M.6
Garruto, R.M.7
Perl, D.P.8
Galasko, D.9
Lee, V.M.10
Trojanowski, J.Q.11
-
7
-
-
41949119043
-
TDP-43 A315T mutation in familial motor neuron disease
-
M.A. Gitcho, R.H. Baloh, S. Chakraverty, K. Mayo, J.B. Norton, D. Levitch, K.J. Hatanpaa, C.L. White III, E.H. Bigio, R. Caselli, M. Baker, M.T. Al-Lozi, J.C. Morris, A. Pestronk, R. Rademakers, A.M. Goate, and N.J. Cairns TDP-43 A315T mutation in familial motor neuron disease Ann. Neurol. 63 2008 535 538
-
(2008)
Ann. Neurol.
, vol.63
, pp. 535-538
-
-
Gitcho, M.A.1
Baloh, R.H.2
Chakraverty, S.3
Mayo, K.4
Norton, J.B.5
Levitch, D.6
Hatanpaa, K.J.7
White Iii, C.L.8
Bigio, E.H.9
Caselli, R.10
Baker, M.11
Al-Lozi, M.T.12
Morris, J.C.13
Pestronk, A.14
Rademakers, R.15
Goate, A.M.16
Cairns, N.J.17
-
8
-
-
77951295221
-
Decreased GLT-1 and increased SOD1 and HO-1 expression in astrocytes contribute to lumbar spinal cord vulnerability of SOD1-G93A transgenic mice
-
Y. Guo, W. Duan, Z. Li, J. Huang, Y. Yin, K. Zhang, Q. Wang, Z. Zhang, and C. Li Decreased GLT-1 and increased SOD1 and HO-1 expression in astrocytes contribute to lumbar spinal cord vulnerability of SOD1-G93A transgenic mice FEBS Lett. 584 2010 1615 1622
-
(2010)
FEBS Lett.
, vol.584
, pp. 1615-1622
-
-
Guo, Y.1
Duan, W.2
Li, Z.3
Huang, J.4
Yin, Y.5
Zhang, K.6
Wang, Q.7
Zhang, Z.8
Li, C.9
-
9
-
-
0032125587
-
Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
-
E.D. Hall, J.A. Oostveen, and M.E. Gurney Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS Glia 23 1998 249 256
-
(1998)
Glia
, vol.23
, pp. 249-256
-
-
Hall, E.D.1
Oostveen, J.A.2
Gurney, M.E.3
-
10
-
-
34249709931
-
TDP-43 is deposited in the Guam parkinsonism-dementia complex brains
-
M. Hasegawa, T. Arai, H. Akiyama, T. Nonaka, H. Mori, T. Hashimoto, M. Yamazaki, and K. Oyanagi TDP-43 is deposited in the Guam parkinsonism-dementia complex brains Brain 130 2007 1386 1394
-
(2007)
Brain
, vol.130
, pp. 1386-1394
-
-
Hasegawa, M.1
Arai, T.2
Akiyama, H.3
Nonaka, T.4
Mori, H.5
Hashimoto, T.6
Yamazaki, M.7
Oyanagi, K.8
-
11
-
-
79960874366
-
The role of mutant TAR DNA-binding protein 43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration
-
J. Janssens, G. Kleinberger, H. Wils, and C. Van Broeckhoven The role of mutant TAR DNA-binding protein 43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration Biochem. Soc. Trans. 39 2011 954 959
-
(2011)
Biochem. Soc. Trans.
, vol.39
, pp. 954-959
-
-
Janssens, J.1
Kleinberger, G.2
Wils, H.3
Van Broeckhoven, C.4
-
12
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Y. Kabeya, N. Mizushima, T. Ueno, A. Yamamoto, T. Kirisako, T. Noda, E. Kominami, Y. Ohsumi, and T. Yoshimori LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing EMBO J. 19 2000 5720 5728
-
(2000)
EMBO J.
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Kominami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
13
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
M. Komatsu, S. Waguri, T. Chiba, S. Murata, J. Iwata, I. Tanida, T. Ueno, M. Koike, Y. Uchiyama, E. Kominami, and K. Tanaka Loss of autophagy in the central nervous system causes neurodegeneration in mice Nature 441 2006 880 884
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
Tanida, I.6
Ueno, T.7
Koike, M.8
Uchiyama, Y.9
Kominami, E.10
Tanaka, K.11
-
14
-
-
36849089101
-
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
-
M. Komatsu, S. Waguri, M. Koike, Y.S. Sou, T. Ueno, T. Hara, N. Mizushima, J. Iwata, J. Ezaki, S. Murata, J. Hamazaki, Y. Nishito, S. Iemura, T. Natsume, T. Yanagawa, J. Uwayama, E. Warabi, H. Yoshida, T. Ishii, A. Kobayashi, M. Yamamoto, Z. Yue, Y. Uchiyama, E. Kominami, and K. Tanaka Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice Cell 131 2007 1149 1163
-
(2007)
Cell
, vol.131
, pp. 1149-1163
-
-
Komatsu, M.1
Waguri, S.2
Koike, M.3
Sou, Y.S.4
Ueno, T.5
Hara, T.6
Mizushima, N.7
Iwata, J.8
Ezaki, J.9
Murata, S.10
Hamazaki, J.11
Nishito, Y.12
Iemura, S.13
Natsume, T.14
Yanagawa, T.15
Uwayama, J.16
Warabi, E.17
Yoshida, H.18
Ishii, T.19
Kobayashi, A.20
Yamamoto, M.21
Yue, Z.22
Uchiyama, Y.23
Kominami, E.24
Tanaka, K.25
more..
-
15
-
-
41449113885
-
Altered macroautophagy in the spinal cord of SOD1 mutant mice
-
L. Li, X. Zhang, and W. Le Altered macroautophagy in the spinal cord of SOD1 mutant mice Autophagy 4 2008 290 293
-
(2008)
Autophagy
, vol.4
, pp. 290-293
-
-
Li, L.1
Zhang, X.2
Le, W.3
-
16
-
-
34249946466
-
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
-
I.R. Mackenzie, E.H. Bigio, P.G. Ince, F. Geser, M. Neumann, N.J. Cairns, L.K. Kwong, M.S. Forman, J. Ravits, H. Stewart, A. Eisen, L. McClusky, H.A. Kretzschmar, C.M. Monoranu, J.R. Highley, J. Kirby, T. Siddique, P.J. Shaw, V.M. Lee, and J.Q. Trojanowski Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations Ann. Neurol. 61 2007 427 434
-
(2007)
Ann. Neurol.
, vol.61
, pp. 427-434
-
-
MacKenzie, I.R.1
Bigio, E.H.2
Ince, P.G.3
Geser, F.4
Neumann, M.5
Cairns, N.J.6
Kwong, L.K.7
Forman, M.S.8
Ravits, J.9
Stewart, H.10
Eisen, A.11
McClusky, L.12
Kretzschmar, H.A.13
Monoranu, C.M.14
Highley, J.R.15
Kirby, J.16
Siddique, T.17
Shaw, P.J.18
Lee, V.M.19
Trojanowski, J.Q.20
more..
-
17
-
-
34548125010
-
Increased autophagy in transgenic mice with a G93A mutant SOD1 gene
-
N. Morimoto, M. Nagai, Y. Ohta, K. Miyazaki, T. Kurata, M. Morimoto, T. Murakami, Y. Takehisa, Y. Ikeda, T. Kamiya, and K. Abe Increased autophagy in transgenic mice with a G93A mutant SOD1 gene Brain Res. 1167 2007 112 117
-
(2007)
Brain Res.
, vol.1167
, pp. 112-117
-
-
Morimoto, N.1
Nagai, M.2
Ohta, Y.3
Miyazaki, K.4
Kurata, T.5
Morimoto, M.6
Murakami, T.7
Takehisa, Y.8
Ikeda, Y.9
Kamiya, T.10
Abe, K.11
-
18
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
M. Neumann, D.M. Sampathu, L.K. Kwong, A.C. Truax, M.C. Micsenyi, T.T. Chou, J. Bruce, T. Schuck, M. Grossman, C.M. Clark, L.F. McCluskey, B.L. Miller, E. Masliah, I.R. Mackenzie, H. Feldman, W. Feiden, H.A. Kretzschmar, J.Q. Trojanowski, and V.M. Lee Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Science 314 2006 130 133
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
MacKenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.19
-
20
-
-
23644462197
-
Ultrastructural study of aggregates in the spinal cord of transgenic mice with a G93A mutant SOD1 gene
-
S. Sasaki, H. Warita, T. Murakami, N. Shibata, T. Komori, K. Abe, M. Kobayashi, and M. Iwata Ultrastructural study of aggregates in the spinal cord of transgenic mice with a G93A mutant SOD1 gene Acta Neuropathol. 109 2005 247 255
-
(2005)
Acta Neuropathol.
, vol.109
, pp. 247-255
-
-
Sasaki, S.1
Warita, H.2
Murakami, T.3
Shibata, N.4
Komori, T.5
Abe, K.6
Kobayashi, M.7
Iwata, M.8
-
21
-
-
58149398638
-
Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease
-
C. Schwab, T. Arai, M. Hasegawa, S. Yu, and P.L. McGeer Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease J. Neuropathol. Exp. Neurol. 67 2008 1159 1165
-
(2008)
J. Neuropathol. Exp. Neurol.
, vol.67
, pp. 1159-1165
-
-
Schwab, C.1
Arai, T.2
Hasegawa, M.3
Yu, S.4
McGeer, P.L.5
-
22
-
-
39349105603
-
The role for oxidative stress in neurodegenerative diseases
-
N. Shibata, and M. Kobayashi The role for oxidative stress in neurodegenerative diseases Brain Nerve 60 2008 157 170
-
(2008)
Brain Nerve
, vol.60
, pp. 157-170
-
-
Shibata, N.1
Kobayashi, M.2
-
23
-
-
80052353946
-
In vivo optical imaging of motor neuron autophagy in a mouse model of amyotrophic lateral sclerosis
-
F. Tian, N. Morimoto, W. Liu, Y. Ohta, K. Deguchi, K. Miyazaki, and K. Abe In vivo optical imaging of motor neuron autophagy in a mouse model of amyotrophic lateral sclerosis Autophagy 7 2011 985 992
-
(2011)
Autophagy
, vol.7
, pp. 985-992
-
-
Tian, F.1
Morimoto, N.2
Liu, W.3
Ohta, Y.4
Deguchi, K.5
Miyazaki, K.6
Abe, K.7
-
24
-
-
44649137415
-
Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies
-
K. Uryu, H. Nakashima-Yasuda, M.S. Forman, L.K. Kwong, C.M. Clark, M. Grossman, B.L. Miller, H.A. Kretzschmar, V.M. Lee, J.Q. Trojanowski, and M. Neumann Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies J. Neuropathol. Exp. Neurol. 67 2008 555 564
-
(2008)
J. Neuropathol. Exp. Neurol.
, vol.67
, pp. 555-564
-
-
Uryu, K.1
Nakashima-Yasuda, H.2
Forman, M.S.3
Kwong, L.K.4
Clark, C.M.5
Grossman, M.6
Miller, B.L.7
Kretzschmar, H.A.8
Lee, V.M.9
Trojanowski, J.Q.10
Neumann, M.11
-
25
-
-
73249152831
-
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
-
I. Wegorzewska, S. Bell, N.J. Cairns, T.M. Miller, and R.H. Baloh TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration Proc. Natl. Acad. Sci. U. S. A. 106 2009 18809 18814
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 18809-18814
-
-
Wegorzewska, I.1
Bell, S.2
Cairns, N.J.3
Miller, T.M.4
Baloh, R.H.5
|