Hemophagocytic lymphohistiocytosis in syntaxin-11-deficient mice: T-cell exhaustion limits fatal disease

Blood

Volumn 121, Issue 4, 2013, Pages 604-613

  Kögl, Tamara ^a   Müller, Jürgen ^b   Jessen, Birthe ^a   Schmitt Graeff, Annette ^a   Janka, Gritta ^c   Ehl, Stephan ^a   Zur Stadt, Udo ^b,c   Aichele, Peter ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b Research Institute   (Germany)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; PERFORIN; SNARE PROTEIN; SYNTAXIN 11; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARENAVIRUS INFECTION; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL FEATURE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; DEGRANULATION; DISEASE COURSE; DISEASE SEVERITY; EFFECTOR CELL; FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS TYPE 4; FATALITY; HEMOPHAGOCYTIC SYNDROME; IMMUNOPHENOTYPING; INTERFERON PRODUCTION; LYMPHOCYTE FUNCTION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; RECEPTOR BLOCKING; SURVIVAL; SYNTAXIN 11 DEFICIENCY; T CELL DEPLETION; T CELL EXHAUSTION; T LYMPHOCYTE;

EID: 84872452706     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-07-441139     Document Type: Article

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