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Volumn , Issue , 2011, Pages 945-965

Antiphospholipid Syndrome: Pathogenesis

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EID: 84872368872     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-374994-9.10050-6     Document Type: Chapter
Times cited : (11)

References (205)
  • 1
    • 33344458573 scopus 로고    scopus 로고
    • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
    • Miyakis S., Lockshin M.D., Atsumi T., Branch D.W., Brey R.L., Cervera R., et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006, 4:295-306.
    • (2006) J Thromb Haemost , vol.4 , pp. 295-306
    • Miyakis, S.1    Lockshin, M.D.2    Atsumi, T.3    Branch, D.W.4    Brey, R.L.5    Cervera, R.6
  • 2
    • 0020518953 scopus 로고
    • Thrombosis, abortion, cerebral disease, and the lupus anticoagulant
    • Hughes G.R. Thrombosis, abortion, cerebral disease, and the lupus anticoagulant. Br Med J (Clin Res Ed) 1983, 287:1088-1089.
    • (1983) Br Med J (Clin Res Ed) , vol.287 , pp. 1088-1089
    • Hughes, G.R.1
  • 3
    • 0036228886 scopus 로고    scopus 로고
    • Antiphospholipid syndrome: Clinical and immunologic manifestations and patterns of disease expression in a cohort of 1000 patients
    • Cervera R., Piette J.C., Font J., Khamashta M.A., Shoenfeld Y., Camps M.T., et al. Antiphospholipid syndrome: Clinical and immunologic manifestations and patterns of disease expression in a cohort of 1000 patients. Arthritis Rheum 2002, 46:1019-1027.
    • (2002) Arthritis Rheum , vol.46 , pp. 1019-1027
    • Cervera, R.1    Piette, J.C.2    Font, J.3    Khamashta, M.A.4    Shoenfeld, Y.5    Camps, M.T.6
  • 5
    • 84904027913 scopus 로고
    • A new serologically active phospholipid from beef heart
    • Pangborn M.C. A new serologically active phospholipid from beef heart. Proc Soc Exp Biol Med 1941, 48:484-486.
    • (1941) Proc Soc Exp Biol Med , vol.48 , pp. 484-486
    • Pangborn, M.C.1
  • 6
    • 0001134916 scopus 로고
    • Observations on the characteristics of an unusual circulating anticoagulant
    • Mueller J.F., Ratnoff O., Henile R.W. Observations on the characteristics of an unusual circulating anticoagulant. J Lab Clin Med 1951, 38:254-261.
    • (1951) J Lab Clin Med , vol.38 , pp. 254-261
    • Mueller, J.F.1    Ratnoff, O.2    Henile, R.W.3
  • 7
    • 0000577842 scopus 로고
    • Systemic lupus erythematosus preceded by false positive test for syphilis: Presentation of five cases
    • Haserick J.R., Long R. Systemic lupus erythematosus preceded by false positive test for syphilis: Presentation of five cases. Ann Intern Med 1951, 37:559-565.
    • (1951) Ann Intern Med , vol.37 , pp. 559-565
    • Haserick, J.R.1    Long, R.2
  • 8
    • 0000398625 scopus 로고
    • The natural history of systemic lupus erythematosus: An approach to its study through chronic biological false positive reactors
    • Moore J.E., Lutz W.B. The natural history of systemic lupus erythematosus: An approach to its study through chronic biological false positive reactors. J Chronic Dis 1955, 1:297-316.
    • (1955) J Chronic Dis , vol.1 , pp. 297-316
    • Moore, J.E.1    Lutz, W.B.2
  • 9
    • 76949112144 scopus 로고
    • Biologically false positive serologic test for syphilis: Type, incidence, and cause
    • Moore J.E., Mohr C.F. Biologically false positive serologic test for syphilis: Type, incidence, and cause. JAMA 1952, 150:467-473.
    • (1952) JAMA , vol.150 , pp. 467-473
    • Moore, J.E.1    Mohr, C.F.2
  • 10
    • 0001145459 scopus 로고
    • A hemorrhagic disorder caused by circulating anticoagulants in patients with disseminated lupus erythematosus
    • Conley C.L., Hartman R.C.A. A hemorrhagic disorder caused by circulating anticoagulants in patients with disseminated lupus erythematosus. J Clin Invest 1952, 31:621-622.
    • (1952) J Clin Invest , vol.31 , pp. 621-622
    • Conley, C.L.1    Hartman, R.C.A.2
  • 11
    • 0000287488 scopus 로고
    • Hypergammaglobulinemia, circulating anticoagulant, and biologic false positive Wassermann reaction: A study in two cases
    • Laurell A.B., Nilsson I.M. Hypergammaglobulinemia, circulating anticoagulant, and biologic false positive Wassermann reaction: A study in two cases. J Lab Clin Med 1957, 49:694-707.
    • (1957) J Lab Clin Med , vol.49 , pp. 694-707
    • Laurell, A.B.1    Nilsson, I.M.2
  • 13
    • 0021029327 scopus 로고
    • Anti-cardiolipin antibodies: Detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus
    • Harris E.N., Gharavi A.E., Boey M.L., Patel B.M., Mackworth-Young C.G., Loizou S., et al. Anti-cardiolipin antibodies: Detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus. Lancet 1983, 2:1211-1214.
    • (1983) Lancet , vol.2 , pp. 1211-1214
    • Harris, E.N.1    Gharavi, A.E.2    Boey, M.L.3    Patel, B.M.4    Mackworth-Young, C.G.5    Loizou, S.6
  • 14
    • 0021319276 scopus 로고
    • Antiphospholipid antibodies and biological false positive serological test for syphilis in patients with systemic lupus erythematosus
    • Koike T., Sueishi M., Funaki H., Tomioka H., Yoshida S. Antiphospholipid antibodies and biological false positive serological test for syphilis in patients with systemic lupus erythematosus. Clin Exp Immunol 1984, 56:193-199.
    • (1984) Clin Exp Immunol , vol.56 , pp. 193-199
    • Koike, T.1    Sueishi, M.2    Funaki, H.3    Tomioka, H.4    Yoshida, S.5
  • 17
    • 0025302635 scopus 로고
    • Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor
    • Galli M., Comfurius P., Maassen C., Hemker H.C., de Baets M.H., van Breda-Vriesman P.J., et al. Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor. Lancet 1990, 335:952-953.
    • (1990) Lancet , vol.335 , pp. 952-953
    • Galli, M.1    Comfurius, P.2    Maassen, C.3    Hemker, H.C.4    de Baets, M.H.5    van Breda-Vriesman, P.J.6
  • 18
    • 0025195938 scopus 로고
    • Anticardiolipin cofactor(s) and differential diagnosis of autoimmune disease
    • Matsuura E., Igarashi Y., Fujimoto M., Ichikawa K., Koike T. Anticardiolipin cofactor(s) and differential diagnosis of autoimmune disease. Lancet 1990, 336:177-178.
    • (1990) Lancet , vol.336 , pp. 177-178
    • Matsuura, E.1    Igarashi, Y.2    Fujimoto, M.3    Ichikawa, K.4    Koike, T.5
  • 19
  • 20
    • 0025951058 scopus 로고
    • Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin
    • Bevers E.M., Galli M., Barbui T., Comfurius P., Zwaal R.F. Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin. Thromb Haemost 1991, 66:629-632.
    • (1991) Thromb Haemost , vol.66 , pp. 629-632
    • Bevers, E.M.1    Galli, M.2    Barbui, T.3    Comfurius, P.4    Zwaal, R.F.5
  • 21
    • 0027253088 scopus 로고
    • Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: An explanation for their pathogenic mechanism?
    • Oosting J.D., Derksen R.H.W.M., Bobbink I.W.G., Hackeng T.M., Bouma B.N., de Groot P.G. Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: An explanation for their pathogenic mechanism?. Blood 1993, 81:2618-2625.
    • (1993) Blood , vol.81 , pp. 2618-2625
    • Oosting, J.D.1    Derksen, R.H.W.M.2    Bobbink, I.W.G.3    Hackeng, T.M.4    Bouma, B.N.5    de Groot, P.G.6
  • 22
    • 0028846868 scopus 로고
    • Autoantibodies to phosphatidylethanolamine (PE) recognize a kininogen-PE complex
    • Sugi T., McIntyre J.A. Autoantibodies to phosphatidylethanolamine (PE) recognize a kininogen-PE complex. Blood 1995, 86:3083-3089.
    • (1995) Blood , vol.86 , pp. 3083-3089
    • Sugi, T.1    McIntyre, J.A.2
  • 23
    • 0033512274 scopus 로고    scopus 로고
    • International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an international workshop
    • Wilson W.A., Gharavi A.E., Koike T., Lockshin M.D., Branch D.W., Piette J.C., et al. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an international workshop. Arthritis Rheum 1999, 42:1309-1311.
    • (1999) Arthritis Rheum , vol.42 , pp. 1309-1311
    • Wilson, W.A.1    Gharavi, A.E.2    Koike, T.3    Lockshin, M.D.4    Branch, D.W.5    Piette, J.C.6
  • 24
    • 0025876649 scopus 로고
    • Static and dynamic lipid asymmetry in cell membranes
    • Devaux P.F. Static and dynamic lipid asymmetry in cell membranes. Biochemistry 1991, 30:1163-1173.
    • (1991) Biochemistry , vol.30 , pp. 1163-1173
    • Devaux, P.F.1
  • 25
    • 0026646802 scopus 로고
    • Bidirectional transbilayer movement of phospholipid analogs in human red blood cells. Evidence for an ATP-dependent and protein-mediated process
    • Connor J., Pak C.H., Zwaal R.F., Schroit A.J. Bidirectional transbilayer movement of phospholipid analogs in human red blood cells. Evidence for an ATP-dependent and protein-mediated process. J Biol Chem 1992, 267:19412-19417.
    • (1992) J Biol Chem , vol.267 , pp. 19412-19417
    • Connor, J.1    Pak, C.H.2    Zwaal, R.F.3    Schroit, A.J.4
  • 26
    • 0030849152 scopus 로고    scopus 로고
    • Molecular cloning of human plasma membrane phospholipid scramblase. A protein mediating transbilayer movement of plasma membrane phospholipids
    • Zhou Q., Zhao J., Stout J.G., Luhm R.A., Wiedmer T., Sims P.J. Molecular cloning of human plasma membrane phospholipid scramblase. A protein mediating transbilayer movement of plasma membrane phospholipids. J Biol Chem 1997, 272:18240-18244.
    • (1997) J Biol Chem , vol.272 , pp. 18240-18244
    • Zhou, Q.1    Zhao, J.2    Stout, J.G.3    Luhm, R.A.4    Wiedmer, T.5    Sims, P.J.6
  • 27
    • 0031043059 scopus 로고    scopus 로고
    • Pathophysiologic implications of membrane phospholipid asymmetry in blood cells
    • Zwaal R.F., Schroit A.J. Pathophysiologic implications of membrane phospholipid asymmetry in blood cells. Blood 1997, 89:1121-1132.
    • (1997) Blood , vol.89 , pp. 1121-1132
    • Zwaal, R.F.1    Schroit, A.J.2
  • 28
    • 0025311157 scopus 로고
    • Surface-dependent reactions of the vitamin K-dependent enzyme complex
    • Mann K.G., Nesheim M.E., Church W.R., Haley P., Krishnaswamy S. Surface-dependent reactions of the vitamin K-dependent enzyme complex. Blood 1990, 76:1-16.
    • (1990) Blood , vol.76 , pp. 1-16
    • Mann, K.G.1    Nesheim, M.E.2    Church, W.R.3    Haley, P.4    Krishnaswamy, S.5
  • 29
    • 0034738623 scopus 로고    scopus 로고
    • Identification of three new members of the phospholipid scramblase gene family
    • Wiedmer T., Zhou Q., Kwoh D.Y., Sims P.J. Identification of three new members of the phospholipid scramblase gene family. Biochim Biophys Acta 2000, 1467:244-253.
    • (2000) Biochim Biophys Acta , vol.1467 , pp. 244-253
    • Wiedmer, T.1    Zhou, Q.2    Kwoh, D.Y.3    Sims, P.J.4
  • 31
    • 34250943252 scopus 로고
    • Uber ein bisher ubekanntes niedermolekulars β2-Globulin des Humanserums
    • Schultze H.E., Heide K., Haput H. Uber ein bisher ubekanntes niedermolekulars β2-Globulin des Humanserums. Naturwissenschaften 1961, 48:719.
    • (1961) Naturwissenschaften , vol.48 , pp. 719
    • Schultze, H.E.1    Heide, K.2    Haput, H.3
  • 33
    • 0025833658 scopus 로고
    • Complete nucleotide and deduced amino acid sequence of human beta 2-glycoprotein I
    • Steinkasserer A., Estaller C., Weiss E.H., Sim R.B., Day A.J. Complete nucleotide and deduced amino acid sequence of human beta 2-glycoprotein I. Biochem J 1991, 277:387-391.
    • (1991) Biochem J , vol.277 , pp. 387-391
    • Steinkasserer, A.1    Estaller, C.2    Weiss, E.H.3    Sim, R.B.4    Day, A.J.5
  • 34
    • 0029777325 scopus 로고    scopus 로고
    • Structure and distribution of modules in extracellular proteins
    • Bork P., Downing A.K., Kieffer B., Campbell I.D. Structure and distribution of modules in extracellular proteins. Q Rev Biophys 1996, 29:119-167.
    • (1996) Q Rev Biophys , vol.29 , pp. 119-167
    • Bork, P.1    Downing, A.K.2    Kieffer, B.3    Campbell, I.D.4
  • 36
    • 0030587953 scopus 로고    scopus 로고
    • Site-directed mutagenesis of recombinant human beta 2-glycoprotein I identifies a cluster of lysine residues that are critical for phospholipid binding and anti-cardiolipin antibody activity
    • Sheng Y., Sali A., Herzog H., Lahnstein J., Krilis S.A. Site-directed mutagenesis of recombinant human beta 2-glycoprotein I identifies a cluster of lysine residues that are critical for phospholipid binding and anti-cardiolipin antibody activity. J Immunol 1996, 157:3744-3751.
    • (1996) J Immunol , vol.157 , pp. 3744-3751
    • Sheng, Y.1    Sali, A.2    Herzog, H.3    Lahnstein, J.4    Krilis, S.A.5
  • 37
    • 0031054567 scopus 로고    scopus 로고
    • Identification of structural mutations in the fifth domain of apolipoprotein H (beta 2-glycoprotein I) which affect phospholipid binding
    • Sanghera D.K., Wagenknecht D.R., McIntyre J.A., Kamboh M.I. Identification of structural mutations in the fifth domain of apolipoprotein H (beta 2-glycoprotein I) which affect phospholipid binding. Hum Mol Genet 1997, 6:311-316.
    • (1997) Hum Mol Genet , vol.6 , pp. 311-316
    • Sanghera, D.K.1    Wagenknecht, D.R.2    McIntyre, J.A.3    Kamboh, M.I.4
  • 38
    • 0033214106 scopus 로고    scopus 로고
    • Adhesion mechanism of human β(2)-glycoprotein I to phospholipids based on its crystal structure
    • Bouma B., de Groot P.G., van den Elsen J.M., Ravelli R.B., Schouten A., Simmelink M.J., et al. Adhesion mechanism of human β(2)-glycoprotein I to phospholipids based on its crystal structure. EMBO J 1999, 18:5166-5174.
    • (1999) EMBO J , vol.18 , pp. 5166-5174
    • Bouma, B.1    de Groot, P.G.2    van den Elsen, J.M.3    Ravelli, R.B.4    Schouten, A.5    Simmelink, M.J.6
  • 40
    • 0034671180 scopus 로고    scopus 로고
    • Identification of the phospholipid-binding site of human beta (2)-glycoprotein I domain V by heteronuclear magnetic resonance
    • Hoshino M., Hagihara Y., Nishii I., Yamazaki T., Kato H., Goto Y. Identification of the phospholipid-binding site of human beta (2)-glycoprotein I domain V by heteronuclear magnetic resonance. J Mol Biol 2000, 304:927-939.
    • (2000) J Mol Biol , vol.304 , pp. 927-939
    • Hoshino, M.1    Hagihara, Y.2    Nishii, I.3    Yamazaki, T.4    Kato, H.5    Goto, Y.6
  • 41
    • 0019308048 scopus 로고
    • Activation of human post heparin lipoprotein lipase by apolipoprotein H (beta 2-glycoprotein I)
    • Nakaya Y., Schaefer E.J., Brewer H.B. Activation of human post heparin lipoprotein lipase by apolipoprotein H (beta 2-glycoprotein I). Biochem Biophys Res Commun 1980, 95:1168-1172.
    • (1980) Biochem Biophys Res Commun , vol.95 , pp. 1168-1172
    • Nakaya, Y.1    Schaefer, E.J.2    Brewer, H.B.3
  • 42
    • 0020081214 scopus 로고
    • Studies on the possible function of beta 2-glycoprotein-I: Influence in the triglyceride metabolism in the rat
    • Wurm H., Beubler E., Polz E., Holasek A., Kostner G. Studies on the possible function of beta 2-glycoprotein-I: Influence in the triglyceride metabolism in the rat. Metabolism 1982, 31:484-486.
    • (1982) Metabolism , vol.31 , pp. 484-486
    • Wurm, H.1    Beubler, E.2    Polz, E.3    Holasek, A.4    Kostner, G.5
  • 43
    • 0034990570 scopus 로고    scopus 로고
    • A specific ligand for beta(2)-glycoprotein I mediates autoantibody-dependent uptake of oxidized low density lipoprotein by macrophages
    • Kobayashi K., Matsuura E., Liu Q., Furukawa J., Kaihara K., Inagaki J., et al. A specific ligand for beta(2)-glycoprotein I mediates autoantibody-dependent uptake of oxidized low density lipoprotein by macrophages. J Lipid Res 2001, 42:697-709.
    • (2001) J Lipid Res , vol.42 , pp. 697-709
    • Kobayashi, K.1    Matsuura, E.2    Liu, Q.3    Furukawa, J.4    Kaihara, K.5    Inagaki, J.6
  • 44
    • 0031934896 scopus 로고    scopus 로고
    • Apoptotic cell clearance in systemic lupus erythematosus. I. Opsonization by antiphospholipid antibodies
    • Manfredi A.A., Rovere P., Galati G., Heltai S., Bozzolo E., Soldini L., et al. Apoptotic cell clearance in systemic lupus erythematosus. I. Opsonization by antiphospholipid antibodies. Arthritis Rheum 1998, 41:205-214.
    • (1998) Arthritis Rheum , vol.41 , pp. 205-214
    • Manfredi, A.A.1    Rovere, P.2    Galati, G.3    Heltai, S.4    Bozzolo, E.5    Soldini, L.6
  • 46
    • 0027328885 scopus 로고
    • 2-glycoprotein I of the factor Xa generating activity of platelets
    • 2-glycoprotein I of the factor Xa generating activity of platelets. Thromb Haemost 1993, 70:342-345.
    • (1993) Thromb Haemost , vol.70 , pp. 342-345
    • Shi, W.1    Chong, B.2    Hogg, P.3    Chesterman, C.4
  • 47
    • 0029057733 scopus 로고
    • Synchronized inhibition of the phospholipid mediated autoactivation of factor XII in plasma by beta 2-glycoprotein I and anti-beta 2-glycoprotein I
    • Schousboe I., Rasmussen M.S. Synchronized inhibition of the phospholipid mediated autoactivation of factor XII in plasma by beta 2-glycoprotein I and anti-beta 2-glycoprotein I. Thromb Haemost 1995, 73:798-804.
    • (1995) Thromb Haemost , vol.73 , pp. 798-804
    • Schousboe, I.1    Rasmussen, M.S.2
  • 48
    • 0023132768 scopus 로고
    • Beta(2)-glycoprotein-I (apo-H) inhibits the release reaction of human platelets during ADP-induced aggregation
    • Nimpf J., Wurm H., Kostner G.M. Beta(2)-glycoprotein-I (apo-H) inhibits the release reaction of human platelets during ADP-induced aggregation. Atherosclerosis 1987, 63:109-114.
    • (1987) Atherosclerosis , vol.63 , pp. 109-114
    • Nimpf, J.1    Wurm, H.2    Kostner, G.M.3
  • 50
    • 0027310143 scopus 로고
    • Human beta 2-glycoprotein I: Molecular analysis of DNA and amino acid polymorphism
    • Steinkasserer A., Dorner C., Wurzner R., Sim R.B. Human beta 2-glycoprotein I: Molecular analysis of DNA and amino acid polymorphism. Hum Genet 1993, 91:401-402.
    • (1993) Hum Genet , vol.91 , pp. 401-402
    • Steinkasserer, A.1    Dorner, C.2    Wurzner, R.3    Sim, R.B.4
  • 52
    • 0032587778 scopus 로고    scopus 로고
    • 2-glycoprotein I at codons 306 and 316 in patients with systemic lupus erythematosus and antiphospholipid syndrome
    • 2-glycoprotein I at codons 306 and 316 in patients with systemic lupus erythematosus and antiphospholipid syndrome. Arthritis Rheum 1999, 42:1189-1193.
    • (1999) Arthritis Rheum , vol.42 , pp. 1189-1193
    • Gushiken, F.C.1    Arnett, F.C.2    Ahn, C.3    Thiagarajan, P.4
  • 53
    • 0033812286 scopus 로고    scopus 로고
    • Beta(2)-glycoprotein I deficiency: Prevalence, genetic background and effects on plasma lipoprotein metabolism and hemostasis
    • Yasuda S., Tustsumi A., Chiba H., Yanai H., Miyoshi Y., Takeuchi R., et al. Beta(2)-glycoprotein I deficiency: Prevalence, genetic background and effects on plasma lipoprotein metabolism and hemostasis. Atherosclerosis 2000, 152:337-346.
    • (2000) Atherosclerosis , vol.152 , pp. 337-346
    • Yasuda, S.1    Tustsumi, A.2    Chiba, H.3    Yanai, H.4    Miyoshi, Y.5    Takeuchi, R.6
  • 54
    • 0034663309 scopus 로고    scopus 로고
    • Coagulation and fibrinolytic activities in 2 siblings with beta(2)-glycoprotein I deficiency
    • Takeuchi R., Atsumi T., Ieko M., Takeya H., Yasuda S., Ichikawa K., et al. Coagulation and fibrinolytic activities in 2 siblings with beta(2)-glycoprotein I deficiency. Blood 2000, 96:1594-1595.
    • (2000) Blood , vol.96 , pp. 1594-1595
    • Takeuchi, R.1    Atsumi, T.2    Ieko, M.3    Takeya, H.4    Yasuda, S.5    Ichikawa, K.6
  • 55
    • 0033824522 scopus 로고    scopus 로고
    • Primary antiphospholipid antibody syndrome with mutations in the phospholipid binding domain of beta(2)-glycoprotein I
    • Gushiken F.C., Arnett F.C., Thiagarajan P. Primary antiphospholipid antibody syndrome with mutations in the phospholipid binding domain of beta(2)-glycoprotein I. Am J Hematol 2000, 65:160-165.
    • (2000) Am J Hematol , vol.65 , pp. 160-165
    • Gushiken, F.C.1    Arnett, F.C.2    Thiagarajan, P.3
  • 59
    • 0028181357 scopus 로고
    • 2-glycoprotein I contains a phospholipid binding site (Cys281-Cys288) and a region recognized by anticardiolipin antibodies
    • 2-glycoprotein I contains a phospholipid binding site (Cys281-Cys288) and a region recognized by anticardiolipin antibodies. J Immunol 1994, 152:653-659.
    • (1994) J Immunol , vol.152 , pp. 653-659
    • Hunt, J.1    Krilis, S.2
  • 60
    • 0027522834 scopus 로고
    • 2-glycoprotein I critical for lipid binding and anti-cardiolipin antibody cofactor activity
    • 2-glycoprotein I critical for lipid binding and anti-cardiolipin antibody cofactor activity. Proc Natl Acad Sci USA 1993, 90:2141-2145.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2141-2145
    • Hunt, J.E.1    Simpson, R.J.2    Krilis, S.A.3
  • 61
    • 0033861268 scopus 로고    scopus 로고
    • Proteolytic cleavage of beta(2)-glycoprotein I: Reduction of antigenicity and the structural relationship
    • Matsuura E., Inagaki J., Kasahara H., Yamamoto D., Atsumi T., Kobayashi K., et al. Proteolytic cleavage of beta(2)-glycoprotein I: Reduction of antigenicity and the structural relationship. Int Immunol 2000, 12:1183-1192.
    • (2000) Int Immunol , vol.12 , pp. 1183-1192
    • Matsuura, E.1    Inagaki, J.2    Kasahara, H.3    Yamamoto, D.4    Atsumi, T.5    Kobayashi, K.6
  • 63
    • 0034530038 scopus 로고    scopus 로고
    • Highly increased plasma concentrations of the nicked form of beta(2) glycoprotein I in patients with leukemia and with lupus anticoagulant: Measurement with a monoclonal antibody specific for a nicked form of domain V
    • Itoh Y., Inuzuka K., Kohno I., Wada H., Shiku H., Ohkura N., et al. Highly increased plasma concentrations of the nicked form of beta(2) glycoprotein I in patients with leukemia and with lupus anticoagulant: Measurement with a monoclonal antibody specific for a nicked form of domain V. J Biochem 2000, 128:1017-1024.
    • (2000) J Biochem , vol.128 , pp. 1017-1024
    • Itoh, Y.1    Inuzuka, K.2    Kohno, I.3    Wada, H.4    Shiku, H.5    Ohkura, N.6
  • 64
    • 2342472560 scopus 로고    scopus 로고
    • 2-glycoprotein I: A marker of cerebral infarct and a novel role in the negative feedback pathway of extrinsic fibrinolysis
    • 2-glycoprotein I: A marker of cerebral infarct and a novel role in the negative feedback pathway of extrinsic fibrinolysis. Blood 2004, 103:3766-3772.
    • (2004) Blood , vol.103 , pp. 3766-3772
    • Yasuda, S.1    Atsumi, T.2    Ieko, M.3    Matsuura, E.4    Kobayashi, K.5    Inagaki, J.6
  • 65
    • 70350509576 scopus 로고    scopus 로고
    • 2-glycoprotein I binds angiostatin 4.5 (plasminogen kringle 1-5) and attenuates its antiangiogenic property
    • 2-glycoprotein I binds angiostatin 4.5 (plasminogen kringle 1-5) and attenuates its antiangiogenic property. Blood 2009, 114:2553-2559.
    • (2009) Blood , vol.114 , pp. 2553-2559
    • Nakagawa, H.1    Yasuda, S.2    Matsuura, E.3    Kobayashi, K.4    Ieko, M.5    Kataoka, H.6
  • 67
    • 0026026703 scopus 로고
    • What is the "true" antigen for anticardiolipin antibodies?
    • Koike T., Matsuura E. What is the "true" antigen for anticardiolipin antibodies?. Lancet 1991, 337:671-672.
    • (1991) Lancet , vol.337 , pp. 671-672
    • Koike, T.1    Matsuura, E.2
  • 68
    • 0026735573 scopus 로고
    • Heterogeneity of anticardiolipin antibodies defined by the anticardiolipin cofactor
    • Matsuura E., Igarashi Y., Fujimoto M., Ichikawa K., Suzuki T., Yoshida S., et al. Heterogeneity of anticardiolipin antibodies defined by the anticardiolipin cofactor. J Immunol 1992, 148:3885-3891.
    • (1992) J Immunol , vol.148 , pp. 3885-3891
    • Matsuura, E.1    Igarashi, Y.2    Fujimoto, M.3    Ichikawa, K.4    Suzuki, T.5    Yoshida, S.6
  • 69
    • 0026817042 scopus 로고
    • 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection
    • 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection. Lupus 1992, 1:75-81.
    • (1992) Lupus , vol.1 , pp. 75-81
    • Hunt, J.E.1    McNeil, H.P.2    Morgan, G.J.3    Crameri, R.M.4    Krilis, S.A.5
  • 70
    • 0030584823 scopus 로고    scopus 로고
    • 2-glycoprotein I as an anticardiolipin cofactor determined using deleted mutants expressed by a Baculovirus system
    • 2-glycoprotein I as an anticardiolipin cofactor determined using deleted mutants expressed by a Baculovirus system. Blood 1996, 87:3262-3270.
    • (1996) Blood , vol.87 , pp. 3262-3270
    • Igarashi, M.1    Matsuura, E.2    Igarashi, Y.3    Nagae, H.4    Ichikawa, K.5    Triplett, D.A.6
  • 72
    • 0037114142 scopus 로고    scopus 로고
    • Use of single point mutations in domain I of beta 2-glycoprotein I to determine fine antigenic specificity of antiphospholipid autoantibodies
    • Iverson G.M., Reddel S., Victoria E.J., Cockerill K.A., Wang Y.X., Marti-Renom M.A., et al. Use of single point mutations in domain I of beta 2-glycoprotein I to determine fine antigenic specificity of antiphospholipid autoantibodies. J Immunol 2002, 169:7097-7103.
    • (2002) J Immunol , vol.169 , pp. 7097-7103
    • Iverson, G.M.1    Reddel, S.2    Victoria, E.J.3    Cockerill, K.A.4    Wang, Y.X.5    Marti-Renom, M.A.6
  • 75
    • 13544276197 scopus 로고    scopus 로고
    • IgG antibodies that recognize epitope Gly40-Arg43 in domain I of beta 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis
    • de Laat B., Derksen R.H., Urbanus R.T., de Groot P.G. IgG antibodies that recognize epitope Gly40-Arg43 in domain I of beta 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis. Blood 2005, 105:1540-1545.
    • (2005) Blood , vol.105 , pp. 1540-1545
    • de Laat, B.1    Derksen, R.H.2    Urbanus, R.T.3    de Groot, P.G.4
  • 76
    • 33846236309 scopus 로고    scopus 로고
    • Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: Mutation studies including residues R39 to R43
    • Ioannou Y., Pericleous C., Giles I., Latchman D.S., Isenberg D.A., Rahman A. Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta(2)-glycoprotein I: Mutation studies including residues R39 to R43. Arthritis Rheum 2007, 56:280-290.
    • (2007) Arthritis Rheum , vol.56 , pp. 280-290
    • Ioannou, Y.1    Pericleous, C.2    Giles, I.3    Latchman, D.S.4    Isenberg, D.A.5    Rahman, A.6
  • 82
    • 0023576914 scopus 로고
    • Quantitative analysis of myocardial infarction in (NZW × BXSB) F1 hybrid mice with systemic lupus erythematosus and small coronary artery disease
    • Yoshida H., Fujiwara H., Fujiwara T., Ikehara S., Hamashima Y. Quantitative analysis of myocardial infarction in (NZW × BXSB) F1 hybrid mice with systemic lupus erythematosus and small coronary artery disease. Am J Pathol 1987, 129:477-485.
    • (1987) Am J Pathol , vol.129 , pp. 477-485
    • Yoshida, H.1    Fujiwara, H.2    Fujiwara, T.3    Ikehara, S.4    Hamashima, Y.5
  • 83
    • 0026777054 scopus 로고
    • Anticardiolipin antibodies in NZW × BXSB F1 mice. A model of antiphospholipid syndrome
    • Hashimoto Y., Kawamura M., Ichikawa K., Suzuki T., Sumida T., Yoshida S., et al. Anticardiolipin antibodies in NZW × BXSB F1 mice. A model of antiphospholipid syndrome. J Immunol 1992, 149:1063-1068.
    • (1992) J Immunol , vol.149 , pp. 1063-1068
    • Hashimoto, Y.1    Kawamura, M.2    Ichikawa, K.3    Suzuki, T.4    Sumida, T.5    Yoshida, S.6
  • 84
    • 0028169961 scopus 로고
    • Immunization with anticardiolipin cofactor (β-2-glycoprotein I) induces experimental antiphospholipid syndrome in naive mice
    • Blank M., Faden D., Tincani A., Kopolovic J., Goldberg I., Gilburd B., et al. Immunization with anticardiolipin cofactor (β-2-glycoprotein I) induces experimental antiphospholipid syndrome in naive mice. J Autoimmun 1994, 7:441-455.
    • (1994) J Autoimmun , vol.7 , pp. 441-455
    • Blank, M.1    Faden, D.2    Tincani, A.3    Kopolovic, J.4    Goldberg, I.5    Gilburd, B.6
  • 85
    • 0028983368 scopus 로고
    • Immunization of a rabbit with beta 2-glycoprotein I induces charge-dependent cross-reactive antibodies that bind anionic phospholipids and have similar reactivity as autoimmune anti-phospholipid antibodies
    • Kouts S., Wang M.X., Adelstein S., Krilis S.A. Immunization of a rabbit with beta 2-glycoprotein I induces charge-dependent cross-reactive antibodies that bind anionic phospholipids and have similar reactivity as autoimmune anti-phospholipid antibodies. J Immonol 1995, 155:958-966.
    • (1995) J Immonol , vol.155 , pp. 958-966
    • Kouts, S.1    Wang, M.X.2    Adelstein, S.3    Krilis, S.A.4
  • 88
    • 0035885939 scopus 로고    scopus 로고
    • 2-glycoprotein I in patients with antiphospholipid syndrome: Preferential recognition of the major phospholipid-binding site
    • 2-glycoprotein I in patients with antiphospholipid syndrome: Preferential recognition of the major phospholipid-binding site. Blood 2001, 98:1889-1896.
    • (2001) Blood , vol.98 , pp. 1889-1896
    • Arai, T.1    Yoshida, K.2    Kaburaki, J.3    Inoko, H.4    Ikeda, Y.5    Kawakami, Y.6
  • 89
    • 13544259567 scopus 로고    scopus 로고
    • Binding of beta 2-glycoprotein I to anionic phospholipids facilitates processing and presentation of a cryptic epitope that activates pathogenic autoreactive T cells
    • Kuwana M., Matsuura E., Kobayashi K., Okazaki Y., Kaburaki J., Ikeda Y., et al. Binding of beta 2-glycoprotein I to anionic phospholipids facilitates processing and presentation of a cryptic epitope that activates pathogenic autoreactive T cells. Blood 2005, 105:1552-1557.
    • (2005) Blood , vol.105 , pp. 1552-1557
    • Kuwana, M.1    Matsuura, E.2    Kobayashi, K.3    Okazaki, Y.4    Kaburaki, J.5    Ikeda, Y.6
  • 90
    • 38049023658 scopus 로고    scopus 로고
    • Excessive exposure to anionic surfaces maintains autoantibody response to beta(2)-glycoprotein I in patients with antiphospholipid syndrome
    • Yamaguchi Y., Seta N., Kaburaki J., Kobayashi K., Matsuura E., Kuwana M. Excessive exposure to anionic surfaces maintains autoantibody response to beta(2)-glycoprotein I in patients with antiphospholipid syndrome. Blood 2007, 110:4312-4318.
    • (2007) Blood , vol.110 , pp. 4312-4318
    • Yamaguchi, Y.1    Seta, N.2    Kaburaki, J.3    Kobayashi, K.4    Matsuura, E.5    Kuwana, M.6
  • 91
    • 50549207211 scopus 로고
    • Thrombosis in systemic lupus erythematosus despite circulating anticoagulants
    • Bowie E.J.W., Thompson J.H., Pascuzzi C.A. Thrombosis in systemic lupus erythematosus despite circulating anticoagulants. J Lab Clin Med 1963, 62:416.
    • (1963) J Lab Clin Med , vol.62 , pp. 416
    • Bowie, E.J.W.1    Thompson, J.H.2    Pascuzzi, C.A.3
  • 92
    • 0018852862 scopus 로고
    • Monoclonal immunoglobulin M lambda coagulation inhibitor with phospholipid specificity. Mechanism of a lupus anticoagulant
    • Thiagarajan P., Shapiro S.S., De Marco L. Monoclonal immunoglobulin M lambda coagulation inhibitor with phospholipid specificity. Mechanism of a lupus anticoagulant. J Clin Invest 1980, 66:397-405.
    • (1980) J Clin Invest , vol.66 , pp. 397-405
    • Thiagarajan, P.1    Shapiro, S.S.2    De Marco, L.3
  • 93
    • 0003135311 scopus 로고
    • Purification and kinetic studies on a circulating anticoagulant in a suspected case of lupus erythematosus
    • Yin E.T., Gaston L.W. Purification and kinetic studies on a circulating anticoagulant in a suspected case of lupus erythematosus. Thromb Haemost 1965, 14:88-115.
    • (1965) Thromb Haemost , vol.14 , pp. 88-115
    • Yin, E.T.1    Gaston, L.W.2
  • 94
    • 0018135382 scopus 로고
    • A sensitive test demonstrating lupus anticoagulant and its behavioural patterns
    • Exner T., Rickard K.A., Kronenberg H. A sensitive test demonstrating lupus anticoagulant and its behavioural patterns. Br J Haematol 1978, 40:143-151.
    • (1978) Br J Haematol , vol.40 , pp. 143-151
    • Exner, T.1    Rickard, K.A.2    Kronenberg, H.3
  • 95
    • 0026581189 scopus 로고
    • Lupus anticoagulant activity is frequently dependent on the presence of beta 2-glycoprotein I
    • Oosting J.D., Derksen R.H., Entjes H.T., Bouma B.N., de Groot P.G. Lupus anticoagulant activity is frequently dependent on the presence of beta 2-glycoprotein I. Thromb Haemost 1992, 67:499-502.
    • (1992) Thromb Haemost , vol.67 , pp. 499-502
    • Oosting, J.D.1    Derksen, R.H.2    Entjes, H.T.3    Bouma, B.N.4    de Groot, P.G.5
  • 98
    • 0031967036 scopus 로고    scopus 로고
    • Monoclonal antibodies against beta-2-glycoprotein I: Use as reference material for lupus anticoagulant tests
    • Arnout J., Vanrusselt M., Wittevrongel C., Vermylen J. Monoclonal antibodies against beta-2-glycoprotein I: Use as reference material for lupus anticoagulant tests. Thromb Haemost 1998, 79:955-958.
    • (1998) Thromb Haemost , vol.79 , pp. 955-958
    • Arnout, J.1    Vanrusselt, M.2    Wittevrongel, C.3    Vermylen, J.4
  • 101
    • 0031984075 scopus 로고    scopus 로고
    • Beta-2-glycoprotein I dependent lupus anticoagulants form stable bivalent antibody beta-2-glycoprotein I complexes on phospholipid surfaces
    • Arnout J., Wittevrongel C., Vanrusselt M., Hoylaerts M., Vermylen J. Beta-2-glycoprotein I dependent lupus anticoagulants form stable bivalent antibody beta-2-glycoprotein I complexes on phospholipid surfaces. Thromb Haemost 1998, 79:79-86.
    • (1998) Thromb Haemost , vol.79 , pp. 79-86
    • Arnout, J.1    Wittevrongel, C.2    Vanrusselt, M.3    Hoylaerts, M.4    Vermylen, J.5
  • 102
    • 0001644081 scopus 로고
    • Prothrombin as a co-factor of the circulating anticoagulant in systemic lupus erythematosus?
    • Loeliger A. Prothrombin as a co-factor of the circulating anticoagulant in systemic lupus erythematosus?. Thromb Diath Haemorrh 1959, 3:237-256.
    • (1959) Thromb Diath Haemorrh , vol.3 , pp. 237-256
    • Loeliger, A.1
  • 103
    • 0000364925 scopus 로고
    • A plasma coagulation defect in systemic lupus erythematosus arising from hypoprothrombinemia combined with antiprothrombinase activity
    • Rapaport S.I., Ames S.B., Duvall B.J. A plasma coagulation defect in systemic lupus erythematosus arising from hypoprothrombinemia combined with antiprothrombinase activity. Blood 1960, 15:212-217.
    • (1960) Blood , vol.15 , pp. 212-217
    • Rapaport, S.I.1    Ames, S.B.2    Duvall, B.J.3
  • 104
    • 0028969513 scopus 로고
    • Differences in the interactions of lupus anticoagulant IgG with human prothrombin and bovine prothrombin
    • Rao L.V.M., Hoang A.D., Rapaport S.I. Differences in the interactions of lupus anticoagulant IgG with human prothrombin and bovine prothrombin. Thromb Haemost 1995, 73:668-674.
    • (1995) Thromb Haemost , vol.73 , pp. 668-674
    • Rao, L.V.M.1    Hoang, A.D.2    Rapaport, S.I.3
  • 105
    • 0025945326 scopus 로고
    • Characterization of a novel liver-specific enhancer in the human prothrombin gene
    • Chow B.K., Ting V., Tufaro F., MacGillivray R.T. Characterization of a novel liver-specific enhancer in the human prothrombin gene. J Biol Chem 1991, 1991:18927-18933.
    • (1991) J Biol Chem , vol.1991 , pp. 18927-18933
    • Chow, B.K.1    Ting, V.2    Tufaro, F.3    MacGillivray, R.T.4
  • 106
    • 0020604029 scopus 로고
    • A mechanism for the hypoprothrombinemia of the acquired hypoprothrombinemia-lupus anticoagulant syndrome
    • Bajaj S.P., Rapaport S.I., Fierer D.S., Herbst K.D., Schwartz D.B. A mechanism for the hypoprothrombinemia of the acquired hypoprothrombinemia-lupus anticoagulant syndrome. Blood 1983, 61:684-692.
    • (1983) Blood , vol.61 , pp. 684-692
    • Bajaj, S.P.1    Rapaport, S.I.2    Fierer, D.S.3    Herbst, K.D.4    Schwartz, D.B.5
  • 107
    • 0021224002 scopus 로고
    • Abnormal prothrombin crossed-immunoelectrophoresis in patients with lupus inhibitors
    • Edson J.R., Vogt J.M., Hasegawa D.K. Abnormal prothrombin crossed-immunoelectrophoresis in patients with lupus inhibitors. Blood 1984, 1984(64):807-816.
    • (1984) Blood , vol.1984 , Issue.64 , pp. 807-816
    • Edson, J.R.1    Vogt, J.M.2    Hasegawa, D.K.3
  • 108
    • 0023772539 scopus 로고
    • Anti-prothrombin antibodies and the lupus anticoagulant
    • Fleck R.A., Rapaport S.I., Rao L.V.M. Anti-prothrombin antibodies and the lupus anticoagulant. Blood 1988, 72:512-519.
    • (1988) Blood , vol.72 , pp. 512-519
    • Fleck, R.A.1    Rapaport, S.I.2    Rao, L.V.M.3
  • 109
    • 0029896410 scopus 로고    scopus 로고
    • Autoantibodies to phospholipid-binding plasma proteins in patients with thrombosis and phospholipid-reactive antibodies
    • 721-714
    • Pengo V., Biasiolo A., Brocco T., Tonetto S., Ruffatti A. Autoantibodies to phospholipid-binding plasma proteins in patients with thrombosis and phospholipid-reactive antibodies. Thromb Haemost 1996, 75. 721-714.
    • (1996) Thromb Haemost , vol.75
    • Pengo, V.1    Biasiolo, A.2    Brocco, T.3    Tonetto, S.4    Ruffatti, A.5
  • 110
    • 0030937274 scopus 로고    scopus 로고
    • Different anticoagulant and immunological properties of anti-prothrombin antibodies in patients with antiphospholipid antibodies
    • Galli M., Beretta G., Daldossi M., Bevers E.M., Barbui T. Different anticoagulant and immunological properties of anti-prothrombin antibodies in patients with antiphospholipid antibodies. Thromb Haemost 1997, 77:486-491.
    • (1997) Thromb Haemost , vol.77 , pp. 486-491
    • Galli, M.1    Beretta, G.2    Daldossi, M.3    Bevers, E.M.4    Barbui, T.5
  • 111
    • 0033711669 scopus 로고    scopus 로고
    • Association of autoantibodies against the phosphatidylserine-prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant
    • Atsumi T., Ieko M., Bertolaccini M.L., Ichikawa K., Tsutsumi A., Matsuura E., et al. Association of autoantibodies against the phosphatidylserine-prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant. Arthritis Rheum 2000, 43:1982-1993.
    • (2000) Arthritis Rheum , vol.43 , pp. 1982-1993
    • Atsumi, T.1    Ieko, M.2    Bertolaccini, M.L.3    Ichikawa, K.4    Tsutsumi, A.5    Matsuura, E.6
  • 112
    • 0028210036 scopus 로고
    • Phospholipid-specific conformational changes in human prothrombin upon binding to procoagulant acidic lipid membranes
    • Wu J.R., Lentz B.R. Phospholipid-specific conformational changes in human prothrombin upon binding to procoagulant acidic lipid membranes. Thromb Haemost 1994, 71:596-604.
    • (1994) Thromb Haemost , vol.71 , pp. 596-604
    • Wu, J.R.1    Lentz, B.R.2
  • 113
    • 0030967015 scopus 로고    scopus 로고
    • Comparison of naturally occurring vitamin K-dependent proteins: Correlation of amino acid sequences and membrane binding properties suggests a membrane contact site
    • McDonald J.F., Shah A.M., Schwalbe R.A., Kisiel W., Dahlback B., Nelsestuen G.L. Comparison of naturally occurring vitamin K-dependent proteins: Correlation of amino acid sequences and membrane binding properties suggests a membrane contact site. Biochemistry 1997, 36:5120-5127.
    • (1997) Biochemistry , vol.36 , pp. 5120-5127
    • McDonald, J.F.1    Shah, A.M.2    Schwalbe, R.A.3    Kisiel, W.4    Dahlback, B.5    Nelsestuen, G.L.6
  • 115
    • 0029959119 scopus 로고    scopus 로고
    • Mechanism and effects of the binding of lupus anticoagulant IgG and prothrombin to surface phospholipid
    • Rao L.V., Hoang A.D., Rapaport S.I. Mechanism and effects of the binding of lupus anticoagulant IgG and prothrombin to surface phospholipid. Blood 1996, 88:4173-4182.
    • (1996) Blood , vol.88 , pp. 4173-4182
    • Rao, L.V.1    Hoang, A.D.2    Rapaport, S.I.3
  • 116
    • 0032704060 scopus 로고    scopus 로고
    • Relationship between clinical features and binding domains of anti-prothrombin autoantibodies in patients with systemic lupus erythematosus and antiphospholipid syndrome
    • Akimoto T., Akama T., Kono I., Sumida T. Relationship between clinical features and binding domains of anti-prothrombin autoantibodies in patients with systemic lupus erythematosus and antiphospholipid syndrome. Lupus 1999, 8:761-766.
    • (1999) Lupus , vol.8 , pp. 761-766
    • Akimoto, T.1    Akama, T.2    Kono, I.3    Sumida, T.4
  • 117
    • 0030861331 scopus 로고    scopus 로고
    • Antiphospholipid antibody: Functional specificity for inhibition of prothrombin activation by the prothrombinase complex
    • Pierangeli S.S., Goldsmith G.H., Branch D.W., Harris E.N. Antiphospholipid antibody: Functional specificity for inhibition of prothrombin activation by the prothrombinase complex. Br J Haematol 1997, 97:768-774.
    • (1997) Br J Haematol , vol.97 , pp. 768-774
    • Pierangeli, S.S.1    Goldsmith, G.H.2    Branch, D.W.3    Harris, E.N.4
  • 118
    • 0034993220 scopus 로고    scopus 로고
    • Complexes of anti-prothrombin antibodies and prothrombin cause lupus anticoagulant activity by competing with the binding of clotting factors for catalytic phospholipid surfaces
    • Simmelink M.J., Horbach D.A., Derksen R.H., Meijers J.C., Bevers E.M., Willems G.M., et al. Complexes of anti-prothrombin antibodies and prothrombin cause lupus anticoagulant activity by competing with the binding of clotting factors for catalytic phospholipid surfaces. Br J Haematol 2001, 113:621-629.
    • (2001) Br J Haematol , vol.113 , pp. 621-629
    • Simmelink, M.J.1    Horbach, D.A.2    Derksen, R.H.3    Meijers, J.C.4    Bevers, E.M.5    Willems, G.M.6
  • 119
    • 0032521453 scopus 로고    scopus 로고
    • 2-glycoprotein I and antiprothrombin antibodies on the anticoagulant activity of activated protein C
    • 2-glycoprotein I and antiprothrombin antibodies on the anticoagulant activity of activated protein C. Blood 1998, 91:1999-2004.
    • (1998) Blood , vol.91 , pp. 1999-2004
    • Galli, M.1    Ruggeri, L.2    Barbui, T.3
  • 120
    • 68049110510 scopus 로고    scopus 로고
    • The effects of phosphatidylserine-dependent antiprothrombin antibody on thrombin generation
    • Sakai Y., Atsumi T., Ieko M., Amengual O., Furukawa S., Furusaki A., et al. The effects of phosphatidylserine-dependent antiprothrombin antibody on thrombin generation. Arthritis Rheum 2009, 60:2457-2467.
    • (2009) Arthritis Rheum , vol.60 , pp. 2457-2467
    • Sakai, Y.1    Atsumi, T.2    Ieko, M.3    Amengual, O.4    Furukawa, S.5    Furusaki, A.6
  • 121
    • 34250679317 scopus 로고    scopus 로고
    • Antiphosphatidylethanolamine antibodies are associated with an increased odds ratio for thrombosis. A multicenter study with the participation of the European Forum on Antiphospholipid Antibodies
    • Sanmarco M., Gayet S., Alessi M.C., Audrain M., de Maistre E., Gris J.C., et al. Antiphosphatidylethanolamine antibodies are associated with an increased odds ratio for thrombosis. A multicenter study with the participation of the European Forum on Antiphospholipid Antibodies. Thromb Haemost 2007, 97:949-954.
    • (2007) Thromb Haemost , vol.97 , pp. 949-954
    • Sanmarco, M.1    Gayet, S.2    Alessi, M.C.3    Audrain, M.4    de Maistre, E.5    Gris, J.C.6
  • 122
  • 123
    • 0029847676 scopus 로고    scopus 로고
    • Phosphatidylethanolamine induces specific conformational changes in the kininogens recognizable by antiphosphatidylethanolamine antibodies
    • Sugi T., Mclntyre J.A. Phosphatidylethanolamine induces specific conformational changes in the kininogens recognizable by antiphosphatidylethanolamine antibodies. Thromb Haemost 1996, 76:354-360.
    • (1996) Thromb Haemost , vol.76 , pp. 354-360
    • Sugi, T.1    Mclntyre, J.A.2
  • 124
    • 0033835807 scopus 로고    scopus 로고
    • Anti-phosphatidylethanolamine (aPE) antibodies: A survey
    • McIntyre J.A., Wagenknecht D.R. Anti-phosphatidylethanolamine (aPE) antibodies: A survey. J Autoimmun 2000, 15:185-193.
    • (2000) J Autoimmun , vol.15 , pp. 185-193
    • McIntyre, J.A.1    Wagenknecht, D.R.2
  • 125
    • 61849105454 scopus 로고    scopus 로고
    • Antiphospholipid antibodies increase the risk of pregnancy-induced hypertension and adverse pregnancy outcomes
    • Yamada H., Atsumi T., Kobashi G., Ota C., Kato E.H., Tsuruga N., et al. Antiphospholipid antibodies increase the risk of pregnancy-induced hypertension and adverse pregnancy outcomes. J Reprod Immunol 2009, 79:188-195.
    • (2009) J Reprod Immunol , vol.79 , pp. 188-195
    • Yamada, H.1    Atsumi, T.2    Kobashi, G.3    Ota, C.4    Kato, E.H.5    Tsuruga, N.6
  • 126
    • 0036121572 scopus 로고    scopus 로고
    • Antibodies to factor XII are distinct from antibodies to prothrombin in patients with the anti-phospholipid syndrome
    • Jone D.W., Nicholls P.J., Donohoe S., Gallimore M.J., Winter M. Antibodies to factor XII are distinct from antibodies to prothrombin in patients with the anti-phospholipid syndrome. Thromb Haemost 2002, 87:426-430.
    • (2002) Thromb Haemost , vol.87 , pp. 426-430
    • Jone, D.W.1    Nicholls, P.J.2    Donohoe, S.3    Gallimore, M.J.4    Winter, M.5
  • 127
    • 34147213486 scopus 로고    scopus 로고
    • Factor XII autoantibodies as a novel marker for thrombosis and adverse obstetric history in patients with systemic lupus erythematosus
    • Bertolaccini M.L., Mepani K., Sanna G., Hughes G.R., Khamashta M.A. Factor XII autoantibodies as a novel marker for thrombosis and adverse obstetric history in patients with systemic lupus erythematosus. Ann Rheum Dis 2007, 66:533-536.
    • (2007) Ann Rheum Dis , vol.66 , pp. 533-536
    • Bertolaccini, M.L.1    Mepani, K.2    Sanna, G.3    Hughes, G.R.4    Khamashta, M.A.5
  • 128
    • 0023766962 scopus 로고
    • Effect of lupus anticoagulant on antithrombotic properties of endothelial cells-Inhibition of thrombomodulin-dependent protein C activation
    • Cariou R., Tobelem G., Bellucci S., Soria J., Soria C., Maclouf J., et al. Effect of lupus anticoagulant on antithrombotic properties of endothelial cells-Inhibition of thrombomodulin-dependent protein C activation. Thromb Haemost 1988, 60:54-58.
    • (1988) Thromb Haemost , vol.60 , pp. 54-58
    • Cariou, R.1    Tobelem, G.2    Bellucci, S.3    Soria, J.4    Soria, C.5    Maclouf, J.6
  • 129
    • 0024433923 scopus 로고
    • Impaired catalytic function of activated protein C: a new in vitro manifestation of lupus anticoagulant
    • Marciniak E., Romond E.H. Impaired catalytic function of activated protein C: a new in vitro manifestation of lupus anticoagulant. Blood 1989, 71:2426-2432.
    • (1989) Blood , vol.71 , pp. 2426-2432
    • Marciniak, E.1    Romond, E.H.2
  • 130
    • 0025001363 scopus 로고
    • Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies
    • Malia R.G., Kitchen S., Greaves M., Preston F.E. Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies. Br J Haematol 1990, 76:101-107.
    • (1990) Br J Haematol , vol.76 , pp. 101-107
    • Malia, R.G.1    Kitchen, S.2    Greaves, M.3    Preston, F.E.4
  • 131
    • 0026786517 scopus 로고
    • Immunoglobulin fractions isolated from patients with antiphospholipid antibodies prevent the inactivation of factor Va by activated protein C on human endothelial cells
    • Borrell M., Sala N., de Castellarnau C., Lopez S., Gari M., Fontcuberta J. Immunoglobulin fractions isolated from patients with antiphospholipid antibodies prevent the inactivation of factor Va by activated protein C on human endothelial cells. Thromb Haemost 1992, 68:101-107.
    • (1992) Thromb Haemost , vol.68 , pp. 101-107
    • Borrell, M.1    Sala, N.2    de Castellarnau, C.3    Lopez, S.4    Gari, M.5    Fontcuberta, J.6
  • 133
    • 17644402397 scopus 로고    scopus 로고
    • Anti-prothrombin IgG from patients with anti-phospholipid antibodies inhibits the inactivation of factor Va by activated protein C
    • Galli M., Willems G.M., Rosing J., Janssen R.M., Govers-Riemslag J.W., Comfurius P., et al. Anti-prothrombin IgG from patients with anti-phospholipid antibodies inhibits the inactivation of factor Va by activated protein C. Br J Haematol 2005, 129:240-247.
    • (2005) Br J Haematol , vol.129 , pp. 240-247
    • Galli, M.1    Willems, G.M.2    Rosing, J.3    Janssen, R.M.4    Govers-Riemslag, J.W.5    Comfurius, P.6
  • 134
    • 0034533468 scopus 로고    scopus 로고
    • Dependence on prothrombin for inhibition of activated protein C activity by lupus antibodies
    • Field S.L., Chesterman C.N., Hogg P.J. Dependence on prothrombin for inhibition of activated protein C activity by lupus antibodies. Thromb Haemost 2000, 84:1132-1133.
    • (2000) Thromb Haemost , vol.84 , pp. 1132-1133
    • Field, S.L.1    Chesterman, C.N.2    Hogg, P.J.3
  • 135
    • 0029794426 scopus 로고    scopus 로고
    • Coagulation activation and fibrinolytic imbalance in subjects with idiopathic antiphospholipid antibodies-A crucial role for acquired free protein S deficiency
    • Ames P.R., Tommasino C., Iannaccone L., Brillante M., Cimino R., Brancaccio V. Coagulation activation and fibrinolytic imbalance in subjects with idiopathic antiphospholipid antibodies-A crucial role for acquired free protein S deficiency. Thromb Haemost 1996, 76:190-194.
    • (1996) Thromb Haemost , vol.76 , pp. 190-194
    • Ames, P.R.1    Tommasino, C.2    Iannaccone, L.3    Brillante, M.4    Cimino, R.5    Brancaccio, V.6
  • 136
    • 0028930108 scopus 로고
    • Acquired free protein S deficiency is associated with antiphospholipid antibodies and increased thrombin generation in patients with systemic lupus erythematosus
    • Ginsberg J., Demers C., Brill-Edwards P., Bona R., Johnston M., Wong A., et al. Acquired free protein S deficiency is associated with antiphospholipid antibodies and increased thrombin generation in patients with systemic lupus erythematosus. Am J Med 1995, 98:379-383.
    • (1995) Am J Med , vol.98 , pp. 379-383
    • Ginsberg, J.1    Demers, C.2    Brill-Edwards, P.3    Bona, R.4    Johnston, M.5    Wong, A.6
  • 137
  • 138
    • 41749120573 scopus 로고    scopus 로고
    • Protein Z levels and anti-protein Z antibodies in patients with arterial and venous thrombosis
    • Pardos-Gea J., Ordi-Ros J., Serrano S., Balada E., Nicolau I., Vilardell M. Protein Z levels and anti-protein Z antibodies in patients with arterial and venous thrombosis. Thromb Res 2008, 121:727-734.
    • (2008) Thromb Res , vol.121 , pp. 727-734
    • Pardos-Gea, J.1    Ordi-Ros, J.2    Serrano, S.3    Balada, E.4    Nicolau, I.5    Vilardell, M.6
  • 139
    • 2142773072 scopus 로고    scopus 로고
    • Autoimmune antiphospholipid antibodies impair the inhibition of activated factor X by protein Z/protein Z-dependent protease inhibitor
    • Forastiero R.R., Martinuzzo M.E., Lu L., Broze G.J. Autoimmune antiphospholipid antibodies impair the inhibition of activated factor X by protein Z/protein Z-dependent protease inhibitor. J Thromb Haemost 2003, 1:1764-1770.
    • (2003) J Thromb Haemost , vol.1 , pp. 1764-1770
    • Forastiero, R.R.1    Martinuzzo, M.E.2    Lu, L.3    Broze, G.J.4
  • 140
    • 1642399591 scopus 로고    scopus 로고
    • Beta 2-glycoprotein I binds factor XI and inhibits its activation by thrombin and factor XIIa: Loss of inhibition by clipped beta 2-glycoprotein I
    • Shi T., Iverson G.M., Qi J.C., Cockerill K.A., Linnik M.D., Konecny P., et al. Beta 2-glycoprotein I binds factor XI and inhibits its activation by thrombin and factor XIIa: Loss of inhibition by clipped beta 2-glycoprotein I. Proc Natl Acad Sci USA 2004, 101:3939-3944.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3939-3944
    • Shi, T.1    Iverson, G.M.2    Qi, J.C.3    Cockerill, K.A.4    Linnik, M.D.5    Konecny, P.6
  • 142
    • 0028266134 scopus 로고
    • Autoantibodies to heparin from patients with antiphospholipid antibody syndrome inhibit formation of antithrombin III-thrombin complexes
    • Shibata S., Harpel P.C., Gharavi A., Rand J., Fillit H. Autoantibodies to heparin from patients with antiphospholipid antibody syndrome inhibit formation of antithrombin III-thrombin complexes. Blood 1994, 83:2532-2540.
    • (1994) Blood , vol.83 , pp. 2532-2540
    • Shibata, S.1    Harpel, P.C.2    Gharavi, A.3    Rand, J.4    Fillit, H.5
  • 143
    • 0026471002 scopus 로고
    • Fibrinolytic potential and antiphospholipid antibodies in systemic lupus erythematosus and other connective tissue disorders
    • Jurado M., Paramo J.A., Gutierrez-Pimentel M., Rocha E. Fibrinolytic potential and antiphospholipid antibodies in systemic lupus erythematosus and other connective tissue disorders. Thromb Haemost 1992, 68:516-520.
    • (1992) Thromb Haemost , vol.68 , pp. 516-520
    • Jurado, M.1    Paramo, J.A.2    Gutierrez-Pimentel, M.3    Rocha, E.4
  • 144
    • 0023915979 scopus 로고
    • Endothelial-dependent fibrinolysis in subjects with the lupus anticoagulant and thrombosis
    • Francis R.B., McGehee J.A., Feinstein D.I. Endothelial-dependent fibrinolysis in subjects with the lupus anticoagulant and thrombosis. Thromb Haemost 1988, 59:412-414.
    • (1988) Thromb Haemost , vol.59 , pp. 412-414
    • Francis, R.B.1    McGehee, J.A.2    Feinstein, D.I.3
  • 145
    • 0025854755 scopus 로고
    • The fibrinolytic response to venous occlusion and the natural anticoagulant in patients with antiphospholipid syndrome both with and without systemic lupus erythematosus
    • Keeling D.M., Campbell S.J., Mackie I.J., Machin S.J., Isenberg D.A. The fibrinolytic response to venous occlusion and the natural anticoagulant in patients with antiphospholipid syndrome both with and without systemic lupus erythematosus. Br J Haematol 1991, 77:354-359.
    • (1991) Br J Haematol , vol.77 , pp. 354-359
    • Keeling, D.M.1    Campbell, S.J.2    Mackie, I.J.3    Machin, S.J.4    Isenberg, D.A.5
  • 146
    • 1542373659 scopus 로고    scopus 로고
    • Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: Evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients
    • Cugno M., Cabibbe M., Galli M., Meroni P.L., Caccia S., Russo R., et al. Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: Evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients. Blood 2004, 103:2121-2126.
    • (2004) Blood , vol.103 , pp. 2121-2126
    • Cugno, M.1    Cabibbe, M.2    Galli, M.3    Meroni, P.L.4    Caccia, S.5    Russo, R.6
  • 147
    • 0036271831 scopus 로고    scopus 로고
    • Autoantibodies to contact proteins in patients with recurrent pregnancy losses
    • Sugi T., Makino T. Autoantibodies to contact proteins in patients with recurrent pregnancy losses. J Reprod Immunol 2002, 53:269-277.
    • (2002) J Reprod Immunol , vol.53 , pp. 269-277
    • Sugi, T.1    Makino, T.2
  • 149
    • 31844447748 scopus 로고    scopus 로고
    • Impaired factor XIIa-dependent activation of fibrinolysis in treated antiphospholipid syndrome gestations developing late-pregnancy complications
    • Carmona F., Lazaro I., Reverter J.C., Tassies D., Font J., Cervera R., et al. Impaired factor XIIa-dependent activation of fibrinolysis in treated antiphospholipid syndrome gestations developing late-pregnancy complications. Am J Obstet Gynecol 2006, 194:457-465.
    • (2006) Am J Obstet Gynecol , vol.194 , pp. 457-465
    • Carmona, F.1    Lazaro, I.2    Reverter, J.C.3    Tassies, D.4    Font, J.5    Cervera, R.6
  • 150
    • 0025766634 scopus 로고
    • Lipoprotein (a) regulates plasminogen activator inhibitor-1 expression in endothelial cells
    • Etingin O.R., Hajjar D.P., Hajjar K.A., Harpel P.C., Nachman R.L. Lipoprotein (a) regulates plasminogen activator inhibitor-1 expression in endothelial cells. J Biol Chem 1991, 266:2459-2465.
    • (1991) J Biol Chem , vol.266 , pp. 2459-2465
    • Etingin, O.R.1    Hajjar, D.P.2    Hajjar, K.A.3    Harpel, P.C.4    Nachman, R.L.5
  • 151
    • 0031985183 scopus 로고    scopus 로고
    • Elevated plasma lipoprotein(a) level and its association with impaired fibrinolysis in patients with antiphospholipid syndrome
    • Atsumi T., Khamashta M.A., Andujar C., Leandro M.J., Amengual O., Ames P.R., et al. Elevated plasma lipoprotein(a) level and its association with impaired fibrinolysis in patients with antiphospholipid syndrome. J Rheumatol 1998, 25:69-73.
    • (1998) J Rheumatol , vol.25 , pp. 69-73
    • Atsumi, T.1    Khamashta, M.A.2    Andujar, C.3    Leandro, M.J.4    Amengual, O.5    Ames, P.R.6
  • 152
    • 0028324892 scopus 로고
    • Plasma levels of lipoprotein(a) are elevated in patients with the antiphospholipid antibody syndrome
    • Yamazaki M., Asakura H., Jokaji H., Saito M., Uotani C., Kumabashiri I., et al. Plasma levels of lipoprotein(a) are elevated in patients with the antiphospholipid antibody syndrome. Thromb Haemost 1994, 71:424-427.
    • (1994) Thromb Haemost , vol.71 , pp. 424-427
    • Yamazaki, M.1    Asakura, H.2    Jokaji, H.3    Saito, M.4    Uotani, C.5    Kumabashiri, I.6
  • 154
    • 0035793334 scopus 로고    scopus 로고
    • Thrombogenic effects of antiphospholipid antibodies are mediated by intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and P-selectin
    • Pierangeli S.S., Espinola R.G., Liu X., Harris E.N. Thrombogenic effects of antiphospholipid antibodies are mediated by intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and P-selectin. Circ Res 2001, 88:245-250.
    • (2001) Circ Res , vol.88 , pp. 245-250
    • Pierangeli, S.S.1    Espinola, R.G.2    Liu, X.3    Harris, E.N.4
  • 155
    • 0006722561 scopus 로고    scopus 로고
    • Human beta 2-glycoprotein I binds to endothelial cells through a cluster of lysine residues that are critical for anionic phospholipid binding and offers epitopes for anti-beta 2-glycoprotein I antibodies
    • Del Papa N., Sheng Y.H., Raschi E., Kandiah D.A., Tincani A., Khamashta M.A., et al. Human beta 2-glycoprotein I binds to endothelial cells through a cluster of lysine residues that are critical for anionic phospholipid binding and offers epitopes for anti-beta 2-glycoprotein I antibodies. J Immunol 1998, 160:5572-5578.
    • (1998) J Immunol , vol.160 , pp. 5572-5578
    • Del Papa, N.1    Sheng, Y.H.2    Raschi, E.3    Kandiah, D.A.4    Tincani, A.5    Khamashta, M.A.6
  • 156
    • 0028365677 scopus 로고
    • Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies
    • Kornberg A., Blank M., Kaufman S., Shoenfeld Y. Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies. J Immunol 1994, 153:1328-1332.
    • (1994) J Immunol , vol.153 , pp. 1328-1332
    • Kornberg, A.1    Blank, M.2    Kaufman, S.3    Shoenfeld, Y.4
  • 157
    • 0031886679 scopus 로고    scopus 로고
    • The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome
    • Amengual O., Atsumi T., Khamashta M.A., Hughes G.R.V. The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome. Thromb Haemost 1998, 79:276-281.
    • (1998) Thromb Haemost , vol.79 , pp. 276-281
    • Amengual, O.1    Atsumi, T.2    Khamashta, M.A.3    Hughes, G.R.V.4
  • 158
    • 0027474773 scopus 로고
    • Induction of endothelial cell tissue factor activity by sera from patients with antiphospholipid syndrome: A possible mechanism of thrombosis
    • Branch D.W., Rodgers G.M. Induction of endothelial cell tissue factor activity by sera from patients with antiphospholipid syndrome: A possible mechanism of thrombosis. Am J Obstet Gynecol 1993, 168:206-210.
    • (1993) Am J Obstet Gynecol , vol.168 , pp. 206-210
    • Branch, D.W.1    Rodgers, G.M.2
  • 159
    • 0032065912 scopus 로고    scopus 로고
    • Arterial disease and thrombosis in the antiphospholipid syndrome: A pathogenic role for endothelin 1
    • Atsumi T., Khamashta M.A., Haworth R.S., Brooks G., Amengual O., Ichikawa K., et al. Arterial disease and thrombosis in the antiphospholipid syndrome: A pathogenic role for endothelin 1. Arthritis Rheum 1998, 41:800-807.
    • (1998) Arthritis Rheum , vol.41 , pp. 800-807
    • Atsumi, T.1    Khamashta, M.A.2    Haworth, R.S.3    Brooks, G.4    Amengual, O.5    Ichikawa, K.6
  • 160
    • 0033495741 scopus 로고    scopus 로고
    • An IgG antiprothrombin antibody enhances prothrombin binding to damaged endothelial cells and shortens plasma coagulation times
    • Zhao Y., Rumold R., Zhu M., Zhou D., Ahmed A.E., Le D.T., et al. An IgG antiprothrombin antibody enhances prothrombin binding to damaged endothelial cells and shortens plasma coagulation times. Arthritis Rheum 1999, 42:2132-2138.
    • (1999) Arthritis Rheum , vol.42 , pp. 2132-2138
    • Zhao, Y.1    Rumold, R.2    Zhu, M.3    Zhou, D.4    Ahmed, A.E.5    Le, D.T.6
  • 161
    • 33748748970 scopus 로고    scopus 로고
    • A human monoclonal antiprothrombin antibody is thrombogenic in vivo and upregulates expression of tissue factor and E-selectin on endothelial cells
    • Vega-Ostertag M., Liu X., Kwan-Ki H., Chen P., Pierangeli S. A human monoclonal antiprothrombin antibody is thrombogenic in vivo and upregulates expression of tissue factor and E-selectin on endothelial cells. Br J Haematol 2006, 135:214-219.
    • (2006) Br J Haematol , vol.135 , pp. 214-219
    • Vega-Ostertag, M.1    Liu, X.2    Kwan-Ki, H.3    Chen, P.4    Pierangeli, S.5
  • 162
    • 11144356959 scopus 로고    scopus 로고
    • Endothelial microparticles: A potential contribution to the thrombotic complications of the antiphospholipid syndrome
    • Dignat-George F., Camoin-Jau L., Sabatier F., Arnoux D., Anfosso F., Bardin N., et al. Endothelial microparticles: A potential contribution to the thrombotic complications of the antiphospholipid syndrome. Thromb Haemost 2004, 91:667-673.
    • (2004) Thromb Haemost , vol.91 , pp. 667-673
    • Dignat-George, F.1    Camoin-Jau, L.2    Sabatier, F.3    Arnoux, D.4    Anfosso, F.5    Bardin, N.6
  • 163
    • 0035424065 scopus 로고    scopus 로고
    • Thromboagglutination by anticardiolipin antibody complex in the antiphospholipid syndrome: A possible mechanism of immune-mediated thrombosis
    • Wiener M.H., Burke M., Fried M., Yust I. Thromboagglutination by anticardiolipin antibody complex in the antiphospholipid syndrome: A possible mechanism of immune-mediated thrombosis. Thromb Res 2001, 103:193-199.
    • (2001) Thromb Res , vol.103 , pp. 193-199
    • Wiener, M.H.1    Burke, M.2    Fried, M.3    Yust, I.4
  • 164
    • 0030866279 scopus 로고    scopus 로고
    • Possible pathogenetic role of activated platelets in the primary antiphospholipid syndrome involving the central nervous system
    • Emmi L., Bergamini C., Spinelli A., Liotta F., Marchione T., Caldini A., et al. Possible pathogenetic role of activated platelets in the primary antiphospholipid syndrome involving the central nervous system. Ann N Y Acad Sci 1997, 823:188-200.
    • (1997) Ann N Y Acad Sci , vol.823 , pp. 188-200
    • Emmi, L.1    Bergamini, C.2    Spinelli, A.3    Liotta, F.4    Marchione, T.5    Caldini, A.6
  • 165
    • 0027408150 scopus 로고
    • 2-Glycoprotein I is a requirement for anticardiolipin antibodies binding to activated platelets: Differences with lupus anticoagulants
    • 2-Glycoprotein I is a requirement for anticardiolipin antibodies binding to activated platelets: Differences with lupus anticoagulants. Blood 1993, 81:1255-1262.
    • (1993) Blood , vol.81 , pp. 1255-1262
    • Shi, W.1    Chong, B.H.2    Chesterman, C.N.3
  • 167
    • 0028586742 scopus 로고
    • Reduction of annexin-V (placental anticoagulant protein-I) on placental villi of women with antiphospholipid antibodies and recurrent spontaneous abortion
    • Rand J.H., Wu X.X., Guller S., Gil J., Guha A., Scher J., et al. Reduction of annexin-V (placental anticoagulant protein-I) on placental villi of women with antiphospholipid antibodies and recurrent spontaneous abortion. Am J Obstet Gynecol 1994, 171:1566-1572.
    • (1994) Am J Obstet Gynecol , vol.171 , pp. 1566-1572
    • Rand, J.H.1    Wu, X.X.2    Guller, S.3    Gil, J.4    Guha, A.5    Scher, J.6
  • 168
    • 0030715044 scopus 로고    scopus 로고
    • Antiphospholipid immunoglobulin G antibodies reduce annexin-V levels on syncytiotrophoblast apical membranes and in culture media of placental villi
    • Rand J.H., Wu X.X., Guller S., Scher J., Andree H.A., Lockwood C.J. Antiphospholipid immunoglobulin G antibodies reduce annexin-V levels on syncytiotrophoblast apical membranes and in culture media of placental villi. Am J Obstet Gynecol 1997, 177:918-923.
    • (1997) Am J Obstet Gynecol , vol.177 , pp. 918-923
    • Rand, J.H.1    Wu, X.X.2    Guller, S.3    Scher, J.4    Andree, H.A.5    Lockwood, C.J.6
  • 169
    • 7244254348 scopus 로고    scopus 로고
    • Detection of antibody-mediated reduction of annexin A5 anticoagulant activity in plasmas of patients with the antiphospholipid syndrome
    • Rand J.H., Wu X.X., Lapinski R., van Heerde W.L., Reutelingsperger C.P., Chen P.P., et al. Detection of antibody-mediated reduction of annexin A5 anticoagulant activity in plasmas of patients with the antiphospholipid syndrome. Blood 2004, 104:2783-2790.
    • (2004) Blood , vol.104 , pp. 2783-2790
    • Rand, J.H.1    Wu, X.X.2    Lapinski, R.3    van Heerde, W.L.4    Reutelingsperger, C.P.5    Chen, P.P.6
  • 170
    • 0028022531 scopus 로고
    • Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody
    • Matsuda J., Saitoh N., Gohchi K., Gotoh M., Tsukamoto M. Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody. Am J Hematol 1994, 47:56-58.
    • (1994) Am J Hematol , vol.47 , pp. 56-58
    • Matsuda, J.1    Saitoh, N.2    Gohchi, K.3    Gotoh, M.4    Tsukamoto, M.5
  • 171
    • 0032080664 scopus 로고    scopus 로고
    • Localization of the apoptosis-inducing activity of lupus anticoagulant in an annexin V-binding antibody subset
    • Nakamura N., Ban T., Yamaji K., Yoneda Y., Wada Y. Localization of the apoptosis-inducing activity of lupus anticoagulant in an annexin V-binding antibody subset. J Clin Invest 1998, 101:1951-1959.
    • (1998) J Clin Invest , vol.101 , pp. 1951-1959
    • Nakamura, N.1    Ban, T.2    Yamaji, K.3    Yoneda, Y.4    Wada, Y.5
  • 172
    • 0028023538 scopus 로고
    • An endothelial cell receptor for plasminogen/tissue plasminogen activator. I. Identity with annexin II
    • Hajjar K.A., Jacovina A.T., Chacko J. An endothelial cell receptor for plasminogen/tissue plasminogen activator. I. Identity with annexin II. J Biol Chem 1994, 269:21191-21197.
    • (1994) J Biol Chem , vol.269 , pp. 21191-21197
    • Hajjar, K.A.1    Jacovina, A.T.2    Chacko, J.3
  • 173
    • 0029845505 scopus 로고    scopus 로고
    • Increased content of annexin II (p36) and p11 in human placenta brush-border membrane vesicles during syncytiotrophoblast maturation and differentiation
    • Kaczan-Bourgois D., Salles J.P., Hullin F., Fauvel J., Moisand A., Duga-Neulat I., et al. Increased content of annexin II (p36) and p11 in human placenta brush-border membrane vesicles during syncytiotrophoblast maturation and differentiation. Placenta 1996, 17:669-676.
    • (1996) Placenta , vol.17 , pp. 669-676
    • Kaczan-Bourgois, D.1    Salles, J.P.2    Hullin, F.3    Fauvel, J.4    Moisand, A.5    Duga-Neulat, I.6
  • 174
    • 0034685886 scopus 로고    scopus 로고
    • High affinity binding of beta 2-glycoprotein I to human endothelial cells is mediated by annexin II
    • Ma K., Simantov R., Zhang J.C., Silverstein R., Hajjar K.A., McCrae K.R. High affinity binding of beta 2-glycoprotein I to human endothelial cells is mediated by annexin II. J Biol Chem 2000, 275:15541-15548.
    • (2000) J Biol Chem , vol.275 , pp. 15541-15548
    • Ma, K.1    Simantov, R.2    Zhang, J.C.3    Silverstein, R.4    Hajjar, K.A.5    McCrae, K.R.6
  • 175
    • 14944367961 scopus 로고    scopus 로고
    • 2 glycoprotein I antibodies
    • 2 glycoprotein I antibodies. Blood 2005, 105:1964-1969.
    • (2005) Blood , vol.105 , pp. 1964-1969
    • Zhang, J.1    McCrae, K.R.2
  • 176
    • 70449509134 scopus 로고    scopus 로고
    • Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo
    • Romay-Penabad Z., Montiel-Manzano M.G., Shilagard T., Papalardo E., Vargas G., Deora A.B., et al. Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo. Blood 2009, 114:3074-3083.
    • (2009) Blood , vol.114 , pp. 3074-3083
    • Romay-Penabad, Z.1    Montiel-Manzano, M.G.2    Shilagard, T.3    Papalardo, E.4    Vargas, G.5    Deora, A.B.6
  • 177
    • 0037528699 scopus 로고    scopus 로고
    • Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies
    • Raschi E., Testoni C., Bosisio D., Borghi M.O., Koike T., Mantovani A., et al. Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies. Blood 2003, 101:3495-3500.
    • (2003) Blood , vol.101 , pp. 3495-3500
    • Raschi, E.1    Testoni, C.2    Bosisio, D.3    Borghi, M.O.4    Koike, T.5    Mantovani, A.6
  • 178
    • 33846899419 scopus 로고    scopus 로고
    • The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies
    • Satta N., Dunoyer-Geindre S., Reber G., Fish R.J., Boehlen F., Kruithof E.K., et al. The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies. Blood 2007, 109:1507-1514.
    • (2007) Blood , vol.109 , pp. 1507-1514
    • Satta, N.1    Dunoyer-Geindre, S.2    Reber, G.3    Fish, R.J.4    Boehlen, F.5    Kruithof, E.K.6
  • 180
    • 34547733912 scopus 로고    scopus 로고
    • 2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts
    • 2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts. Arthritis Rheum 2007, 56:2687-2697.
    • (2007) Arthritis Rheum , vol.56 , pp. 2687-2697
    • Sorice, M.1    Longo, A.2    Capozzi, A.3    Garofalo, T.4    Misasi, R.5    Alessandri, C.6
  • 183
    • 0041571482 scopus 로고    scopus 로고
    • Differential binding of ligands to the apolipoprotein E receptor 2
    • Andersen O.M., Benhayon D., Curran T., Willnow T.E. Differential binding of ligands to the apolipoprotein E receptor 2. Biochemistry 2004, 42:9355-9364.
    • (2004) Biochemistry , vol.42 , pp. 9355-9364
    • Andersen, O.M.1    Benhayon, D.2    Curran, T.3    Willnow, T.E.4
  • 184
    • 0141445991 scopus 로고    scopus 로고
    • Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2'
    • Lutters B.C., Derksen R.H., Tekelenburg W.L., Lenting P.J., Arnout J., de Groot P.G. Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2'. J Biol Chem 2003, 278:33831-33838.
    • (2003) J Biol Chem , vol.278 , pp. 33831-33838
    • Lutters, B.C.1    Derksen, R.H.2    Tekelenburg, W.L.3    Lenting, P.J.4    Arnout, J.5    de Groot, P.G.6
  • 187
    • 33846443236 scopus 로고    scopus 로고
    • Platelet adhesion to dimeric beta-glycoprotein I under conditions of flow is mediated by at least two receptors: Glycoprotein Ibalpha and apolipoprotein E receptor 2'
    • Pennings M.T., Derksen R.H., van Lummel M., Adelmeijer J., VanHoorelbeke K., Urbanus R.T., et al. Platelet adhesion to dimeric beta-glycoprotein I under conditions of flow is mediated by at least two receptors: Glycoprotein Ibalpha and apolipoprotein E receptor 2'. J Thromb Haemost 2007, 5:369-377.
    • (2007) J Thromb Haemost , vol.5 , pp. 369-377
    • Pennings, M.T.1    Derksen, R.H.2    van Lummel, M.3    Adelmeijer, J.4    VanHoorelbeke, K.5    Urbanus, R.T.6
  • 188
    • 10344248906 scopus 로고    scopus 로고
    • Factor XI interacts with the leucine-rich repeats of glycoprotein Ibalpha on the activated platelet
    • Baglia F.A., Shrimpton C.N., Emsley J., Kitagawa K., Ruggeri Z.M., Lopez J.A., et al. Factor XI interacts with the leucine-rich repeats of glycoprotein Ibalpha on the activated platelet. J Biol Chem 2004, 279:49323-49329.
    • (2004) J Biol Chem , vol.279 , pp. 49323-49329
    • Baglia, F.A.1    Shrimpton, C.N.2    Emsley, J.3    Kitagawa, K.4    Ruggeri, Z.M.5    Lopez, J.A.6
  • 189
    • 0037217897 scopus 로고    scopus 로고
    • Thrombogenicity of beta 2-glycoprotein I-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster
    • Jankowski M., Vreys I., Wittevrongel C., Boon D., Vermylen J., Hoylaerts M.F., et al. Thrombogenicity of beta 2-glycoprotein I-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster. Blood 2003, 101:157-162.
    • (2003) Blood , vol.101 , pp. 157-162
    • Jankowski, M.1    Vreys, I.2    Wittevrongel, C.3    Boon, D.4    Vermylen, J.5    Hoylaerts, M.F.6
  • 190
    • 3242697048 scopus 로고    scopus 로고
    • Characterization of monocyte tissue factor activity induced by IgG antiphospholipid antibodies and inhibition by dilazep
    • Zhou H., Wolberg A.S., Roubey R.A. Characterization of monocyte tissue factor activity induced by IgG antiphospholipid antibodies and inhibition by dilazep. Blood 2004, 104:2353-2358.
    • (2004) Blood , vol.104 , pp. 2353-2358
    • Zhou, H.1    Wolberg, A.S.2    Roubey, R.A.3
  • 192
    • 0036847630 scopus 로고    scopus 로고
    • NFkappaB is an essential intermediate in the activation of endothelial cells by anti-beta(2) glycoprotein 1 antibodies
    • Dunoyer-Geindre S., De Moerloose P., Galve-De Rochemonteix B., Reber G., Kruithof E. NFkappaB is an essential intermediate in the activation of endothelial cells by anti-beta(2) glycoprotein 1 antibodies. Thromb Haemost 2002, 88:851-857.
    • (2002) Thromb Haemost , vol.88 , pp. 851-857
    • Dunoyer-Geindre, S.1    De Moerloose, P.2    Galve-De Rochemonteix, B.3    Reber, G.4    Kruithof, E.5
  • 194
    • 4444273214 scopus 로고    scopus 로고
    • Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin
    • Vega-Ostertag M., Harris E.N., Pierangeli S.S. Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin. Arthritis Rheum 2004, 50:2911-2919.
    • (2004) Arthritis Rheum , vol.50 , pp. 2911-2919
    • Vega-Ostertag, M.1    Harris, E.N.2    Pierangeli, S.S.3
  • 195
    • 18644361988 scopus 로고    scopus 로고
    • Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies
    • Vega-Ostertag M., Casper K., Swerlick R., Ferrara D., Harris E.N., Pierangeli S.S. Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies. Arthritis Rheum 2005, 52:1545-1554.
    • (2005) Arthritis Rheum , vol.52 , pp. 1545-1554
    • Vega-Ostertag, M.1    Casper, K.2    Swerlick, R.3    Ferrara, D.4    Harris, E.N.5    Pierangeli, S.S.6
  • 196
    • 0242299717 scopus 로고    scopus 로고
    • Protein kinase C alpha requirement in the activation of p38 mitogen-activated protein kinase, which is linked to the induction of tumor necrosis factor alpha in lipopolysaccharide-stimulated microglia
    • Nakajima K., Tohyama Y., Kohsaka S., Kurihara T. Protein kinase C alpha requirement in the activation of p38 mitogen-activated protein kinase, which is linked to the induction of tumor necrosis factor alpha in lipopolysaccharide-stimulated microglia. Neurochem Int 2004, 44:205-214.
    • (2004) Neurochem Int , vol.44 , pp. 205-214
    • Nakajima, K.1    Tohyama, Y.2    Kohsaka, S.3    Kurihara, T.4
  • 197
    • 31044449865 scopus 로고    scopus 로고
    • Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-kappaB/Rel proteins via the p38 mitogen-activated protein kinase pathway, and of the MEK-1/ERK pathway
    • Lopez-Pedrera C., Buendia P., Cuadrado M.J., Siendones E., Aguirre M.A., Barbarroja N., et al. Antiphospholipid antibodies from patients with the antiphospholipid syndrome induce monocyte tissue factor expression through the simultaneous activation of NF-kappaB/Rel proteins via the p38 mitogen-activated protein kinase pathway, and of the MEK-1/ERK pathway. Arthritis Rheum 2006, 54:301-311.
    • (2006) Arthritis Rheum , vol.54 , pp. 301-311
    • Lopez-Pedrera, C.1    Buendia, P.2    Cuadrado, M.J.3    Siendones, E.4    Aguirre, M.A.5    Barbarroja, N.6
  • 198
    • 9144243607 scopus 로고    scopus 로고
    • Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation
    • Girardi G., Redecha P., Salmon J.E. Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation. Nat Med 2004, 10:1222-1226.
    • (2004) Nat Med , vol.10 , pp. 1222-1226
    • Girardi, G.1    Redecha, P.2    Salmon, J.E.3
  • 199
    • 33749590636 scopus 로고    scopus 로고
    • Complement as a predictor of further miscarriage in couples with recurrent miscarriages
    • Sugiura-Ogasawara M., Nozawa K., Nakanishi T., Hattori Y., Ozaki Y. Complement as a predictor of further miscarriage in couples with recurrent miscarriages. Hum Reprod 2006, 21:2711-2714.
    • (2006) Hum Reprod , vol.21 , pp. 2711-2714
    • Sugiura-Ogasawara, M.1    Nozawa, K.2    Nakanishi, T.3    Hattori, Y.4    Ozaki, Y.5
  • 200
    • 0026706529 scopus 로고
    • Antiphospholipid antibodies and complement activation in patients with cerebral ischemia
    • Davis W.D., Brey R.L. Antiphospholipid antibodies and complement activation in patients with cerebral ischemia. Clin Exp Rheumatol 1992, 10:455-460.
    • (1992) Clin Exp Rheumatol , vol.10 , pp. 455-460
    • Davis, W.D.1    Brey, R.L.2
  • 201
    • 22244485396 scopus 로고    scopus 로고
    • Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia
    • Pierangeli S.S., Girardi G., Vega-Ostertag M., Liu X., Espinola R.G., Salmon J. Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia. Arthritis Rheum 2005, 52:2120-2124.
    • (2005) Arthritis Rheum , vol.52 , pp. 2120-2124
    • Pierangeli, S.S.1    Girardi, G.2    Vega-Ostertag, M.3    Liu, X.4    Espinola, R.G.5    Salmon, J.6
  • 203
    • 67449159236 scopus 로고    scopus 로고
    • Complement activation in patients with primary antiphospholipid syndrome
    • Oku K., Atsumi T., Bohgaki M., Amengual O., Kataoka H., Horita T., et al. Complement activation in patients with primary antiphospholipid syndrome. Ann Rheum Dis 2009, 68:1030-1035.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1030-1035
    • Oku, K.1    Atsumi, T.2    Bohgaki, M.3    Amengual, O.4    Kataoka, H.5    Horita, T.6
  • 204
    • 0030784716 scopus 로고    scopus 로고
    • Anticardiolipin IgG subclasses: Association of IgG2 with arterial and/or venous thrombosis
    • Sammaritano L.R., Ng S., Sobel R., Lo S.K., Simantov R., Furie R., et al. Anticardiolipin IgG subclasses: Association of IgG2 with arterial and/or venous thrombosis. Arthritis Rheum 1997, 40:1998-2006.
    • (1997) Arthritis Rheum , vol.40 , pp. 1998-2006
    • Sammaritano, L.R.1    Ng, S.2    Sobel, R.3    Lo, S.K.4    Simantov, R.5    Furie, R.6
  • 205
    • 85080849012 scopus 로고    scopus 로고
    • 2-glycoprotein I as the basis for the association between IgG2 anticardiolipin antibodies and thrombosis in the antiphospholipid syndrome
    • 2-glycoprotein I as the basis for the association between IgG2 anticardiolipin antibodies and thrombosis in the antiphospholipid syndrome. Arthritis Rheum 1998, 41:1513-1515.
    • (1998) Arthritis Rheum , vol.41 , pp. 1513-1515
    • Amengual, O.1    Atsumi, T.2    Khamashta, M.A.3    Bertolaccini, M.L.4    Hughes, G.R.5


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