Identification of three new members of the phospholipid scramblase gene family

Biochimica et Biophysica Acta - Biomembranes

Volumn 1467, Issue 1, 2000, Pages 244-253

  Wiedmer, Therese ^a   Zhou, Quansheng ^a   Kwoh, Deborah Y ^a   Sims, Peter J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Phospholipid asymmetry; Phospholipid scramblase; Plasma membrane

Indexed keywords

CALCIUM ION; COMPLEMENTARY DNA; MEMBRANE PHOSPHOLIPID; SCRAMBLASE;

ARTICLE; CALCIUM TRANSPORT; CHROMOSOME 17; CHROMOSOME 3Q; CONTROLLED STUDY; DAUDI CELL; GENE CLUSTER; GENE LIBRARY; GENOME; HUMAN; HUMAN CELL; LIPID BILAYER; MOLECULAR CLONING; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHOSPHOLIPID TRANSFER; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; BASE SEQUENCE; CARRIER PROTEINS; CHROMOSOME MAPPING; CLONING, MOLECULAR; GENE DELETION; GENES, REPORTER; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PANCREAS; PHOSPHOLIPID TRANSFER PROTEINS; PHOSPHOLIPIDS; PHYLOGENY; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0034738623     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2736(00)00236-4     Document Type: Article

References (20)

1. Schroit A.J., Zwaal R.F.A. Transbilayer movement of phospholipids in red cell and platelet membranes. Biochim. Biophys. Acta. 1071:1991;313-329.
2. Devaux P. Static and dynamic lipid asymmetry in cell membranes. Biochemistry. 30:1991;1163-1173.
3. Bevers E.M., Comfurius P., Dekkers D.W.C., Zwaal R.F.A. Lipid translocation across the plasma membrane of mammalian cells. Biochim. Biophys. Acta. 1439:1999;317-330.
4. Sims P.J., Faioni E.M., Wiedmer T., Shattil S.J. Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity. J. Biol. Chem. 263:1988;18205-18212.
5. Wang R.H., Phillips G. Jr., Medof M.E., Mold C. Activation of the alternative complement pathway by exposure of phosphatidylethanolamine and phosphatidylserine on erythrocytes from sickle cell disease patients. J. Clin. Invest. 92:1993;1326-1335.
6. Williamson P., Schlegel R.A. Back and forth: the regulation and function of transbilayer phospholipid movement in eukaryotic cells. Mol. Membr. Biol. 11:1994;199-216.
7. Fadok V.A., Bratton D.L., Frasch S.C., Warner M.L., Henson P.M. The role of phosphatidylserine in recognition of apoptotic cells by phagocytes. Cell Death Differ. 5:1998;551-562.
8. 2+ induces transbilayer redistribution of all major phospholipids in human erythrocytes. Biochemistry. 31:1992;6355-6360.
9. Chang C.-P., Zhao J., Wiedmer T., Sims P.J. Contribution of platelet microparticle formation and granule secretion to the transmembrane migration of phosphatidylserine. J. Biol. Chem. 268:1993;7171-7178.
10. Smeets E.F., Comfurius P., Bevers E.M., Zwaal R.F.A. Calcium-induced transbilayer scrambling of fluorescent phospholipid analogs in platelets and erythrocytes. Biochim. Biophys. Acta. 1195:1994;281-286.
11. 2+-dependent transbilayer movement of phospholipid. J. Biol. Chem. 271:1996;17205-17210.
12. Zhou Q., Zhao J., Stout J.G., Luhm R.A., Wiedmer T., Sims P.J. Molecular cloning of human plasma membrane phospholipid scramblase - A protein mediating transbilayer movement of plasma membrane phospholipids. J. Biol. Chem. 272:1997;18240-18244.
13. Zhao J., Zhou Q., Wiedmer T., Sims P.J. Level of expression of phospholipid scramblase regulates induced movement of phosphatidylserine to the cell surface. J. Biol. Chem. 273:1998;6603-6606.
14. 2+-accelerated transbilayer movement of membrane phospholipids. Biochemistry. 37:1998;2356-2360.
15. Kasukabe T., Kobayashi H., Kaneko Y., Okabe-Kado J., Honma Y. Identity of human normal counterpart (MmTRA1b) of mouse leukemogenesis-associated gene (MmTRA1a) product as plasma membrane phospholipid scramblase and chromosome mapping of the human MmTRA1b phospholipid scramblase gene. Biochem. Biophys. Res. Commun. 249:1998;449-455.
16. Kasukabe T., Okabe-Kado J., Honma Y. TRA1, a novel mRNA highly expressed in leukemogenic mouse monocytic sublines but not in nonleukemogenic sublines. Blood. 89:1997;2975-2985.
17. Zhou Q., Zhao J., Al-Zoghaibi F., Zhou A., Wiedmer T., Silverman R.H., Sims P.J. Transcriptional control of the human plasma membrane phospholipid scramblase 1 gene is mediated by interferon α Blood. 95:2000;2593-2599.
18. Rickles R.J., Botfield M.C., Weng Z., Taylor J.A., Green O.M., Brugge J.S., Zoller M.J. Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries. EMBO J. 13:1994;5598-5604.
19. Bork P., Schultz J., Ponting C.P. Cytoplasmic signalling domains: the next generation. Trends Biochem. Sci. 22:1997;296-298.
20. Thompson J.D., Higgins D.G., Gibson T.J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:1994;4673-4680.