Human β2-glycoprotein I binds to endothelial cells through a cluster of lysine residues that are critical for anionic phospholipid binding and offers epitopes for anti-β2-glycoprotein I antibodies

Journal of Immunology

Volumn 160, Issue 11, 1998, Pages 5572-5578

  Del Papa, N ^a   Sheng, Y H ^b   Raschi, E ^a   Kandiah, D A ^b   Tincani, A ^c   Khamashta, M A ^d   Atsumi, T ^d   Hughes, G R V ^d   Ichikawa, K ^e   Koike, T ^e   Balestrieri, G ^c   Krilis, S A ^b   Meroni, P L ^a,f  

^a UNIVERSITY OF MILAN   (Italy)

^b ST GEORGE HOSPITAL   (Australia)

^c Servizio di Immunologia Clinica   (Italy)

^d ST THOMAS HOSPITAL   (United Kingdom)

^e HOKKAIDO UNIVERSITY   (Japan)

^f IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; BETA2 GLYCOPROTEIN 1; CARDIOLIPIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; EPITOPE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 6; LYSINE; MUTANT PROTEIN; PHOSPHOLIPID; PROTEIN ANTIBODY; SYNTHETIC PEPTIDE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; ENDOTHELIUM CELL; FETUS WASTAGE; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; PROTEIN DOMAIN; THROMBOSIS;

AMINO ACID SEQUENCE; ANIONS; ANTIBODIES, MONOCLONAL; AUTOANTIBODIES; BETA 2-GLYCOPROTEIN I; BINDING SITES, ANTIBODY; CELLS, CULTURED; E-SELECTIN; ENDOTHELIUM, VASCULAR; EPITOPES; GLYCOPROTEINS; HUMANS; INTERLEUKIN-6; LYSINE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PHOSPHOLIPIDS; PROTEIN BINDING; UMBILICAL VEINS; UP-REGULATION;

EID: 0006722561     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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