Acute 5-HT1A autoreceptor knockdown increases antidepressant responses and serotonin release in stressful conditions

Psychopharmacology

Volumn 225, Issue 1, 2013, Pages 61-74

  Ferrés Coy, Albert ^a,c   Santana, Noemí ^a,c   Castañé, Anna ^a,c   Cortés, Roser ^a,d   Carmona, María C ^e   Toth, Miklos ^f   Montefeltro, Andrés ^e   Artigas, Francesc ^a,c   Bortolozzi, Analía ^a,b,c  

^a INST D INVESTIGACIONS B   (Spain)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE SALUD MENTAL CIBERSAM   (Spain)

^d CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^e N Life Therapeutics SL   (Spain)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

5 HT1A receptor; Antidepressant effects; Depression; RNA interference; Serotonin; Stress

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; FLUOXETINE; MESSENGER RNA; SEROTONIN 1A RECEPTOR; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; CONTROLLED STUDY; DEPRESSION; DORSAL RAPHE NUCLEUS; EXTRACELLULAR SPACE; FORCED SWIMMING TEST; MALE; MEDIAL PREFRONTAL CORTEX; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PREFRONTAL CORTEX; PRIORITY JOURNAL; SEROTONIN BRAIN LEVEL; SEROTONIN RELEASE; SEROTONINERGIC NERVE CELL; STRESS; TAIL FLICK TEST;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; AUTORECEPTORS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; FLUOXETINE; GENE KNOCKDOWN TECHNIQUES; HYPOTHERMIA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRODIALYSIS; PREFRONTAL CORTEX; RAPHE NUCLEI; RECEPTOR, SEROTONIN, 5-HT1A; RNA, MESSENGER; RNA, SMALL INTERFERING; SEROTONIN; SEROTONIN UPTAKE INHIBITORS; STRESS, PSYCHOLOGICAL;

EID: 84872299801     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-012-2795-9     Document Type: Article

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