Regional patterns of compensation following genetic deletion of either 5-hydroxytryptamine1A or 5-hydroxytryptamine1B receptor in the mouse

Journal of Pharmacology and Experimental Therapeutics

Volumn 298, Issue 3, 2001, Pages 1092-1100

  Knobelman, Deborah A ^a   Hen, René ^b   Blendy, Julie A ^a   Lucki, Irwin ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 5 PROPOXY 3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDINE; AUTORECEPTOR; FLUOXETINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DESENSITIZATION; GENE DELETION; HIPPOCAMPUS; MALE; MEDIAN RAPHE NUCLEUS; MOUSE; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR SENSITIVITY; REGULATORY MECHANISM; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; AREA UNDER CURVE; FLUOXETINE; GENE DELETION; GENOTYPE; MALE; MICE; MICE, KNOCKOUT; MICRODIALYSIS; PIPERAZINES; PYRIDINES; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SEROTONIN UPTAKE INHIBITORS;

EID: 0034883670     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. 1A antagonists
2. Current advances and trends in the treatment of depression
3. 1 receptor agonists and p-chloroamphetamine
4. 1B receptor is localized predominantly on axon terminals
5. 1A receptors mediate 5-hydroxytryptamine release in the amygdala through a feedback to the caudal linear raphe
6. 1B knockout mice
7. Differential effects of ipsapirone on 5-hydroxytryptamine release in the dorsal and median raphe neuronal pathways
8. 1A receptors control 5-HT release in the rat medial prefrontal cortex
9. The selective 5-HT1A agonists alnespirone (S-20499) and 8-OH-DPAT reduce extracellular 5-hydroxytryptamine in rat brain in a regionally-selective manner
10. 1A agonists: Recent developments and controversial issues
11. 1B binding sites
12. 1B knock-out mice
13. 1B receptors with WAY 100635 and GR 127, 935
14. Inhibition of median and dorsal raphe neurones following administration of the selective serotonin reuptake inhibitor paroxetine
15. 1A receptor mutant mice
16. Effect of fluoxetine on extracellular 5-hydroxytryptamine in rat brain. Role of 5-HT autoreceptors
17. Role of uptake inhibition and autoreceptor activation in the control of 5-HT release in the frontal cortex and dorsal hippocampus of the rat
18. Serotonin autoreceptor function and antidepressant drug action
19. 1A receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo
20. 8-Hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT a potent and selective simplified ergot cogener with central 5-HT receptor stimulating activity
21. 1A receptors in the effects of acute and chronic fluoxetine on extracellular serotonin in the frontal cortex
22. 1A receptor antagonists on citalopram-induced increase in extracellular serotonin in the frontal cortex, striatum, and dorsal hippocampus
23. 1B autoreceptors in different brain regions
24. 1B receptors
25. 1A autoreceptors by chronic administration of 8-OH-DPAT
26. 1A autoreceptors of the dorsal and median raphe nuclei
27. Effects of acute and repeated administration of antidepressant drugs on extracellular levels of 5-hydroxytryptamine measured in vivo
28. The presence of a 5-HT uptake inhibitor alters pharmacological manipulations of 5-HT release
29. 1B autoreceptors limit the effects of selective serotonin re-uptake inhibitors in mouse hippocampus and frontal cortex
30. Regional differences in the effect of the combined treatment of WAY 100635 and fluoxetine: An in vivo microdialysis study
31. 1 receptor
32. 1A receptor
33. 1A receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission
34. Complications associated with genetic background effects in research using knockout mice
35. Autoregulation of serotonin neurons: Role in antidepressant drug action
36. Serotonin receptor 1A knockout: An animal model of anxiety-related disorder
37. Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor
38. Combined administration of a 5-hydroxytryptamine (5-HT)ID antagonist and 5-HT reuptake inhibitor increases 5-HT release in guinea pig hypothalamus in vivo
39. 1A receptor antagonists in the dorsal raphe pathway: Role of somatodendritic autoreceptors
40. Increased extracellular serotonin produced by uptake inhibition enhanced after chronic treatment with fluoxetine
41. 1B receptor
42. 5-HT receptor knockout mice: Pharmacological tools or models of psychiatric disorders
43. 1B receptor antagonists on extracellular 5-HT in rat frontal cortex in vivo
44. 1 receptor
45. 1B agonists: A comparative study with dorsal raphe neurons
46. 1B receptors: In vivo microdialysis studies
47. Pharmacogenetics and the serotonin system: Initial studies and future directions
48. A PHA-L analysis of ascending projections of the dorsal raphe nucleus in the rat
49. Projections of the median raphe nucleus in the rat
50. 1B receptors