Novel limonene and citral based 2,5-disubstituted-1,3,4-oxadiazoles: A natural product coupled approach to semicarbazones for antiepileptic activity

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 3, 2013, Pages 864-868

  Rajak, Harish ^a   Singh Thakur, Bhupendra ^a   Singh, Avineesh ^a   Raghuvanshi, Kamlesh ^a   Sah, Anil Kumar ^a   Veerasamy, Ravichandran ^b   Sharma, Prabodh Chander ^c   Singh Pawar, Rajesh ^d   Kharya, Murli Dhar ^e  

^a GURU GHASIDAS UNIVERSITY   (India)

^b AIMST UNIVERSITY   (Malaysia)

^c KURUKSHETRA UNIVERSITY   (India)

^d VNS Institute of Pharmacy   (India)

^e DR H S GOUR UNIVERSITY   (India)

Author keywords

1,3,4 Oxadiazoles; Anticonvulsant activity; Citral; Limonene; Semicarbazones

Indexed keywords

1,3,4 OXADIAZOLE DERIVATIVE; 4 AMINOBUTYRIC ACID; ANTICONVULSIVE AGENT; CARBAMAZEPINE; ETHOSUXIMIDE; LIMONENE; PENTYLENETRTRAZOLE; PHENYTOIN; SEMICARBAZONE DERIVATIVE; STRYCHNINE; UNCLASSIFIED DRUG; VALPROIC ACID;

ANTICONVULSANT ACTIVITY; ARTICLE; BINDING SITE; DRUG BINDING; DRUG DETERMINATION; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; NEUROTOXICITY; NONHUMAN; PHARMACOPHORE; ROTAROD TEST; SEIZURE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTICONVULSANTS; BINDING SITES; CYCLOHEXENES; DISEASE MODELS, ANIMAL; GAMMA-AMINOBUTYRIC ACID; MONOTERPENES; OXADIAZOLES; PROTEIN BINDING; RATS; SEIZURES; SEMICARBAZONES; STRUCTURE-ACTIVITY RELATIONSHIP; TERPENES;

STRYCHNOS TOXIFERA;

EID: 84872286311     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.11.051     Document Type: Article

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