2,4-Dimethoxyphenylsemicarbazones with anticonvulsant activity against three animal models of seizures: Synthesis and pharmacological evaluation

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 9, 2006, Pages 3106-3112

  Thirumurugan, Rathinasabapathy ^a   Sriram, Dharmarajan ^a   Saxena, Amrita ^a   Stables, James ^b   Yogeeswari, Perumal ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

2,4 Dimethoxy; Anticonvulsant; Aryl semicarbazones; GABA

Indexed keywords

2,4 DIMETHOXYANILINE; 2,4 DIMETHOXYPHENYLSEMICARBAZONE DERIVATIVE; 4 AMINOBUTYRIC ACID; ANTICONVULSIVE AGENT; CARBAMIC ACID DERIVATIVE; PENTETRAZOLE; STRYCHNINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC SHOCK; NEUROTOXICITY; SEIZURE;

ANIMALS; ANTICONVULSANTS; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; GAMMA-AMINOBUTYRIC ACID; MALE; MICE; MOLECULAR STRUCTURE; OXYGEN; RATS; SEIZURES; SEMICARBAZONES; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; STRYCHNOS TOXIFERA;

EID: 33644982586     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.12.041     Document Type: Article

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