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Volumn 342, Issue 8, 2009, Pages 453-461

Synthesis of novel 2,5-disubstituted 1,3,4-thiadiazoles for their potential anticonvulsant activity: Pharmacophoric model studies

(6) Rajak, Harish a Deshmukh, Ravitas a Aggarwal, Navneet b Kashaw, Sushil c Kharya, Murli Dhar c Mishra, Pradeep d

a GURU GHASIDAS UNIVERSITY (India)

b Lachoo Memorial College of Science and Technology (India)

c DR H S GOUR UNIVERSITY (India)

d GLA Group (India)

Author keywords

1,3,4 Thiadiazoles; Anticonvulsant activity; Semicarbazones

Indexed keywords

1,3,4 THIADIAZOLE DERIVATIVE; ANTICONVULSIVE AGENT; CARBAMAZEPINE; PENTETRAZOLE; PHENYTOIN; SEMICARBAZONE DERIVATIVE; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC SHOCK; EXPERIMENTAL MODEL; INFRARED SPECTROSCOPY; MALE; MASS SPECTROMETRY; MOTOR DYSFUNCTION; MOUSE; NEUROTOXICITY; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SEIZURE; SEIZURE THRESHOLD; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; ANTICONVULSANTS; BINDING SITES; DRUG EVALUATION, PRECLINICAL; ELECTROSHOCK; MALE; MICE; MOLECULAR STRUCTURE; PENTYLENETETRAZOLE; RATS; RATS, WISTAR; SEIZURES; SEMICARBAZONES; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES;

EID: 68249112815 PISSN: 03656233 EISSN: 15214184 Source Type: Journal
DOI: 10.1002/ardp.200800213 Document Type: Article

Times cited : (67)

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