-
1
-
-
84856433589
-
Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010
-
Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA 2012; 307: 483-490.
-
(2012)
JAMA
, vol.307
, pp. 483-490
-
-
Ogden, C.L.1
Carroll, M.D.2
Kit, B.K.3
Flegal, K.M.4
-
2
-
-
84872110745
-
-
World Health Organization. Obesity and Overweight Fact sheet Number 311 Accessed: 25 November 2011
-
World Health Organization. Obesity and Overweight Fact sheet Number 311. http://www.who.int/mediacentre/factsheets/fs311/en/index.html. Accessed: 25 November 2011.
-
-
-
-
3
-
-
74549159752
-
Prevalence of high body mass index in US children and adolescents, 2007-2008
-
Ogden CL, Carroll MD, Curtin LR, Lamb MM, Flegal KM. Prevalence of high body mass index in US children and adolescents, 2007-2008. JAMA 2010; 303: 242-249.
-
(2010)
JAMA
, vol.303
, pp. 242-249
-
-
Ogden, C.L.1
Carroll, M.D.2
Curtin, L.R.3
Lamb, M.M.4
Flegal, K.M.5
-
4
-
-
78649473912
-
The levelling off of the obesity epidemic since the year 1999 - A review of evidence and perspectives
-
Rokholm B, Baker JL, Sorensen TI. The levelling off of the obesity epidemic since the year 1999 - a review of evidence and perspectives. Obes Rev 2010; 11: 835-846.
-
(2010)
Obes Rev
, vol.11
, pp. 835-846
-
-
Rokholm, B.1
Baker, J.L.2
Sorensen, T.I.3
-
5
-
-
53849114637
-
Childhood overweight and obesity prevalences levelling off in Stockholm but socioeconomic differ-ences persist
-
Sundblom E, Petzold M, Rasmussen F, Callmer E, Lissner L. Childhood overweight and obesity prevalences levelling off in Stockholm but socioeconomic differ-ences persist. Int J Obes (Lond) 2008; 32: 1525-1530.
-
(2008)
Int J Obes (Lond)
, vol.32
, pp. 1525-1530
-
-
Sundblom, E.1
Petzold, M.2
Rasmussen, F.3
Callmer, E.4
Lissner, L.5
-
6
-
-
67649083769
-
Stabilization of overweight prevalence in French children between
-
Salanave B, Peneau S, Rolland-Cachera MF, Hercberg S, Castetbon K. Stabilization of overweight prevalence in French children between 2000 and 2007. Int J Pediatr Obes 2009; 4: 66-72.
-
(2000)
Int J Pediatr Obes
, Issue.4
, pp. 66-72
-
-
Salanave, B.1
Peneau, S.2
Rolland-Cachera, M.F.3
Hercberg, S.4
Castetbon, K.5
-
7
-
-
64849095087
-
Prevalence ofoverweight in 6- to 15-year-old children in central/ western France from 1996 to 2006: Trends toward stabilization
-
Peneau S, Salanave B, Maillard-Teyssier L, Rolland-Cachera MF, Vergnaud AC, Mejean C et al. Prevalence ofoverweight in 6- to 15-year-old children in central/ western France from 1996 to 2006: trends toward stabilization. Int J Obes (Lond) 2009; 33: 401-407.
-
(2009)
Int J Obes (Lond)
, vol.33
, pp. 401-407
-
-
Peneau, S.1
Salanave, B.2
Maillard-Teyssier, L.3
Rolland-Cachera, M.F.4
Vergnaud, A.C.5
Mejean, C.6
-
8
-
-
80052880082
-
Evidence that the prevalence ofchildhood overweight is plateauing: Data from nine countries
-
Olds T, Maher C, Zumin S, Peneau S, Lioret S, Castetbon K et al. Evidence that the prevalence ofchildhood overweight is plateauing: data from nine countries. Int J Pediatr Obes 2011; 6: 342-360.
-
(2011)
Int J Pediatr Obes
, vol.6
, pp. 342-360
-
-
Olds, T.1
Maher, C.2
Zumin, S.3
Peneau, S.4
Lioret, S.5
Castetbon, K.6
-
9
-
-
33749446753
-
Worldwide trends in childhood overweight and obesity
-
Wang Y, Lobstein T.Worldwide trends in childhood overweight and obesity. Int J Pediatr Obes 2006; 1: 11-25.
-
(2006)
Int J Pediatr Obes
, vol.1
, pp. 11-25
-
-
Wang, Y.1
Lobstein, T.2
-
10
-
-
54549113348
-
Obesity in children Part 1: Epidemiology, mea-surement, risk factors, and screening
-
Kipping RR, Jago R, Lawlor DA. Obesity in children. Part 1: Epidemiology, mea-surement, risk factors, and screening. BMJ 2008; 337: a1824.
-
(2008)
BMJ
, vol.337
-
-
Kipping, R.R.1
Jago, R.2
Lawlor, D.A.3
-
12
-
-
41849141673
-
Pre-vention and treatment of pediatric obesity: An endocrine society clinical practice guideline based on expert opinion
-
August GP, Caprio S, Fennoy I, Freemark M, Kaufman FR, Lustig RH et al. Pre-vention and treatment of pediatric obesity: an endocrine society clinical practice guideline based on expert opinion. J Clin Endocrinol Metab 2008; 93: 4576-4599.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4576-4599
-
-
August, G.P.1
Caprio, S.2
Fennoy, I.3
Freemark, M.4
Kaufman, F.R.5
Lustig, R.H.6
-
13
-
-
30844462089
-
The world health organization' s global strategy on diet, physical activity, and health: Turning strategy into action
-
Lee E. The world health organization's global strategy on diet, physical activity, and health: Turning strategy into action. Food Drug Law J 2005; 60: 569-601.
-
(2005)
Food Drug Law J
, vol.60
, pp. 569-601
-
-
Lee, E.1
-
14
-
-
34447261863
-
Relation of body mass index and waist-to-height ratio to cardiovascular disease risk factors in children and adolescents: The Bogalusa Heart Study
-
Freedman DS, Kahn HS, Mei Z, Grummer-Strawn LM, Dietz WH, Srinivasan SR et al. Relation of body mass index and waist-to-height ratio to cardiovascular disease risk factors in children and adolescents: the Bogalusa Heart Study. Am J Clin Nutr 2007; 86: 33-40.
-
(2007)
Am J Clin Nutr
, vol.86
, pp. 33-40
-
-
Freedman, D.S.1
Kahn, H.S.2
Mei, Z.3
Grummer-Strawn, L.M.4
Dietz, W.H.5
Srinivasan, S.R.6
-
15
-
-
67649853281
-
Relation of body mass index and skinfold thicknesses to cardiovascular disease riskfactors in children: The Bogalusa Heart Study
-
Freedman DS, Katzmarzyk PT, Dietz WH, Srinivasan SR, Berenson GS. Relation of body mass index and skinfold thicknesses to cardiovascular disease riskfactors in children: the Bogalusa Heart Study. Am J Clin Nutr 2009; 90: 210-216.
-
(2009)
Am J Clin Nutr
, vol.90
, pp. 210-216
-
-
Freedman, D.S.1
Katzmarzyk, P.T.2
Dietz, W.H.3
Srinivasan, S.R.4
Berenson, G.S.5
-
16
-
-
0035430207
-
Evaluation of the insulin resistance syndrome in 5- to 10-year-old overweight/obese African-American children
-
Young-Hyman D, Schlundt DG, Herman L, De Luca F, Counts D. Evaluation of the insulin resistance syndrome in 5- to 10-year-old overweight/obese African-American children. Diabetes Care 2001; 24: 1359-1364.
-
(2001)
Diabetes Care
, vol.24
, pp. 1359-1364
-
-
Young-Hyman, D.1
Schlundt, D.G.2
Herman, L.3
De Luca, F.4
Counts, D.5
-
17
-
-
0033995603
-
Presence of metabolic cardiovascular syn-drome in obese children
-
Csabi G, Torok K, Jeges S, Molnar D. Presence of metabolic cardiovascular syn-drome in obese children. Eur J Pediatr 2000; 159: 91-94.
-
(2000)
Eur J Pediatr
, vol.159
, pp. 91-94
-
-
Csabi, G.1
Torok, K.2
Jeges, S.3
Molnar, D.4
-
18
-
-
64949086459
-
Complications of obesity in children and adolescents
-
Daniels SR. Complications of obesity in children and adolescents. Int J Obes (Lond) 2009; 33(Suppl 1): S60-S65.
-
(2009)
Int J Obes (Lond)
, vol.33
, Issue.SUPPL. 1
-
-
Daniels, S.R.1
-
19
-
-
36849015926
-
Childhood body-mass index and the risk of coronary heart disease in adulthood
-
Baker JL, Olsen LW, Sorensen TI. Childhood body-mass index and the risk of coronary heart disease in adulthood. N Engl J Med 2007; 357: 2329-2337.
-
(2007)
N Engl J Med
, vol.357
, pp. 2329-2337
-
-
Baker, J.L.1
Olsen, L.W.2
Sorensen, T.I.3
-
20
-
-
81455135755
-
Childhood adiposity, adult adiposity, and cardiovascular riskfactors
-
Juonala M, Magnussen CG, Berenson GS, Venn A, Burns TL, Sabin MA et al. Childhood adiposity, adult adiposity, and cardiovascular riskfactors. N Engl JMed 2011;365: 1876-1885.
-
(2011)
N Engl JMed
, vol.365
, pp. 1876-1885
-
-
Juonala, M.1
Magnussen, C.G.2
Berenson, G.S.3
Venn, A.4
Burns, T.L.5
Sabin, M.A.6
-
21
-
-
0026672612
-
Long-term morbidity and mortality of overweight adolescents. A follow-up of the Harvard Growth Study of 1922 to 1935
-
Must A, Jacques PF, Dallal GE, Bajema CJ, Dietz WH. Long-term morbidity and mortality of overweight adolescents. A follow-up of the Harvard Growth Study of 1922 to 1935. N Engl J Med 1992; 327: 1350-1355.
-
(1992)
N Engl J Med
, vol.327
, pp. 1350-1355
-
-
Must, A.1
Jacques, P.F.2
Dallal, G.E.3
Bajema, C.J.4
Dietz, W.H.5
-
22
-
-
57349174466
-
Clinical review: Treatment of pediatric obesity: A systematic review and meta-analysis of randomized trials
-
Mc Govern L, Johnson JN, Paulo R, Hettinger A, Singhal V, Kamath C etal. Clinical review: treatment of pediatric obesity: a systematic review and meta-analysis of randomized trials. J Clin Endocrinol Metab 2008; 93: 4600-4605.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4600-4605
-
-
Mc Govern, L.1
Johnson, J.N.2
Paulo, R.3
Hettinger, A.4
Singhal, V.5
Kamath, C.6
-
23
-
-
33645102431
-
Reducing Obesity and Related Chronic Disease Risk in Children and Youth: A Synthesis of Evidence with 'best practice' recommendations
-
Flynn MA, Mc Neil DA, Maloff B, Mutasingwa D, Wu M, Ford C et al. Reducing obesity and related chronic disease risk in children and youth: a synthesis of evidence with 'best practice' recommendations. Obes Rev 2006; 7(Suppl 1): 7-66.
-
(2006)
Obes Rev
, vol.7
, Issue.SUPPL. 1
, pp. 7-66
-
-
Flynn, M.A.1
Mc Neil, D.A.2
Maloff, B.3
Mutasingwa, D.4
Wu, M.5
Ford, C.6
-
24
-
-
70349161670
-
Interventions for treating obesity in children
-
Oude Luttikhuis H, Baur L, Jansen H, Shrewsbury VA, O'Malley C, Stolk RP. Interventions for treating obesity in children. Cochrane Database Syst Rev 2009, CD001872.
-
(2009)
Cochrane Database Syst Rev
-
-
Oude Luttikhuis, H.1
Baur, L.2
Jansen, H.3
Shrewsbury, V.A.4
O'Malley, C.5
Stolk, R.P.6
-
26
-
-
33846513449
-
A meta-analysis of family-behavioral weight-loss treatments for children
-
Young KM, Northern JJ, Lister KM, Drummond JA, O'Brien WH. A meta-analysis of family-behavioral weight-loss treatments for children. Clin Psychol Rev 2007; 27: 240-249.
-
(2007)
Clin Psychol Rev
, vol.27
, pp. 240-249
-
-
Young, K.M.1
Northern, J.J.2
Lister, K.M.3
Drummond, J.A.4
O'Brien, W.H.5
-
27
-
-
76049096979
-
-
An Updated, Targeted Systematic Review for the US Preventive Services Task Force. Agency for Healthcare Research and Quality (US); Report No.: 10-05144-EF-1. Evidence Synthesis, No 76. January 2010
-
Whitlock EP, O'Conner EA, Williams SB, Beil TL, Lutz KW. Effectiveness of Primary Care Interventions for Weight Management in Children and Adolescents. An Updated, Targeted Systematic Review for the US Preventive Services Task Force. Agency for Healthcare Research and Quality (US); Report No.: 10-05144-EF-1. Evidence Synthesis, No. 76. January 2010.
-
Effectiveness of Primary Care Interventions for Weight Management in Children and Adolescents
-
-
Whitlock, E.P.1
O'Conner, E.A.2
Williams, S.B.3
Beil, T.L.4
Lutz, K.W.5
-
28
-
-
2642534355
-
Prevention and treatment of overweight in chil-dren and adolescents
-
Fowler-Brown A, Kahwati LC. Prevention and treatment of overweight in chil-dren and adolescents. Am Fam Physician 2004; 69: 2591-2598.
-
(2004)
Am Fam Physician
, vol.69
, pp. 2591-2598
-
-
Fowler-Brown, A.1
Kahwati, L.C.2
-
29
-
-
70349751672
-
Family-based treatment of severe pediatric obesity: Randomized, controlled trial
-
Kalarchian MA, Levine MD, Arslanian SA, Ewing LJ, Houck PR, Cheng Y et al. Family-based treatment of severe pediatric obesity: randomized, controlled trial. Pediatrics 2009; 124: 1060-1068.
-
(2009)
Pediatrics
, vol.124
, pp. 1060-1068
-
-
Kalarchian, M.A.1
Levine, M.D.2
Arslanian, S.A.3
Ewing, L.J.4
Houck, P.R.5
Cheng, Y.6
-
30
-
-
0028509888
-
Ten-year outcomes of behavioral family-based treatment for childhood obesity
-
Epstein LH, Valoski A, Wing RR, Mc Curley J. Ten-year outcomes of behavioral family-based treatment for childhood obesity. Health Psychol1994; 13: 373-383.
-
(1994)
Health Psychol
, vol.13
, pp. 373-383
-
-
Epstein, L.H.1
Valoski, A.2
Wing, R.R.3
Mc Curley, J.4
-
31
-
-
77949484958
-
A meta-analysis of obesity interventions among U.S. minority children
-
Seo DC, Sa J. A meta-analysis of obesity interventions among U.S. minority children. JAdolesc Health 2010; 46: 309-323.
-
(2010)
JAdolesc Health
, vol.46
, pp. 309-323
-
-
Seo, D.C.1
Sa, J.2
-
32
-
-
34547671002
-
Family-based obesity treat-ment, then and now: Twenty-five years of pediatric obesity treatment
-
Epstein LH, Paluch RA, Roemmich JN, Beecher MD. Family-based obesity treat-ment, then and now: twenty-five years of pediatric obesity treatment. Health Psychol 2007; 26: 381-391.
-
(2007)
Health Psychol
, vol.26
, pp. 381-391
-
-
Epstein, L.H.1
Paluch, R.A.2
Roemmich, J.N.3
Beecher, M.D.4
-
33
-
-
38449107149
-
Recommendations for treatment of child and adolescent overweight and obe-sity
-
Spear BA, Barlow SE, Ervin C, Ludwig DS, Saelens BE, Schetzina KE et al. Recommendations for treatment of child and adolescent overweight and obe-sity. Pediatrics 2007; 120(Suppl 4): S254-S288.
-
(2007)
Pediatrics
, vol.120
, Issue.SUPPL. 4
-
-
Spear, B.A.1
Barlow, S.E.2
Ervin, C.3
Ludwig, D.S.4
Saelens, B.E.5
Schetzina, K.E.6
-
34
-
-
38449095758
-
Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: Summary report
-
Barlow SE. Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. Pediatrics 2007; 120(Suppl 4): S164-S192.
-
(2007)
Pediatrics
, vol.120
, Issue.SUPPL. 4
-
-
Barlow, S.E.1
-
35
-
-
84055213533
-
Expert panel on integrated guidelines for cardiovascular health and risk reduc-tion in children and adolescents: Summary report
-
Expert panel on integrated guidelines for cardiovascular health and risk reduc-tion in children and adolescents: summary report. Pediatrics 2011; 128(Suppl 5): S213-S256.
-
(2011)
Pediatrics
, vol.128
, Issue.SUPPL. 5
-
-
-
36
-
-
27844487932
-
Randomized trial of lifestyle modification and pharmacotherapy for obesity
-
Wadden TA, Berkowitz RI, Womble LG, Sarwer DB, Phelan S, Cato RK et al. Randomized trial of lifestyle modification and pharmacotherapy for obesity. N Engl J Med 2005; 353: 2111-2120.
-
(2005)
N Engl J Med
, vol.353
, pp. 2111-2120
-
-
Wadden, T.A.1
Berkowitz, R.I.2
Womble, L.G.3
Sarwer, D.B.4
Phelan, S.5
Cato, R.K.6
-
37
-
-
0037840394
-
Behavior therapy and sibutramine for the treatment of adolescent obesity: A randomized controlled trial
-
Berkowitz RI, Wadden TA, Tershakovec AM, Cronquist JL. Behavior therapy and sibutramine for the treatment of adolescent obesity: a randomized controlled trial. JAMA 2003; 289: 1805-1812.
-
(2003)
JAMA
, vol.289
, pp. 1805-1812
-
-
Berkowitz, R.I.1
Wadden, T.A.2
Tershakovec, A.M.3
Cronquist, J.L.4
-
38
-
-
0034909757
-
Intensive therapiesfor pediatric obesity
-
Yanovski JA. Intensive therapiesfor pediatric obesity. Pediatr Clin North Am 2001; 48: 1041-1053.
-
(2001)
Pediatr Clin North Am
, vol.48
, pp. 1041-1053
-
-
Yanovski, J.A.1
-
39
-
-
84872114808
-
-
NHLBI NIH Guidelines, NHLBI, DHHS: Bethesda, MD
-
Daniels SR, Benuck I, Christakis DA, Dennison BA, Gidding SS, Gillman MW et al. Overweight and Obesity. Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents: The Report of the Expert Panel. NHLBI NIH Guidelines, NHLBI, DHHS: Bethesda, MD, 2011, pp 282-320.
-
(2011)
Overweight and Obesity. Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents: The Report of the Expert Panel
, pp. 282-320
-
-
Daniels, S.R.1
Benuck, I.2
Christakis, D.A.3
Dennison, B.A.4
Gidding, S.S.5
Gillman, M.W.6
-
41
-
-
0027260870
-
Neurochemical mechanism of action ofanorectic drugs
-
Samanin R, Garattini S. Neurochemical mechanism of action ofanorectic drugs. Pharmacol Toxicol 1993; 73: 63-68.
-
(1993)
Pharmacol Toxicol
, vol.73
, pp. 63-68
-
-
Samanin, R.1
Garattini, S.2
-
42
-
-
0013850437
-
Phentermine resinate in obesity Clinical trial of Mirapront in adipose children
-
von Spranger J. Phentermine resinate in obesity. Clinical trial of Mirapront in adipose children. Munch Med Wochenschr 1965; 107: 1833-1834.
-
(1965)
Munch Med Wochenschr
, vol.107
, pp. 1833-1834
-
-
Von Spranger, J.1
-
43
-
-
0014095264
-
Treatment of obesity in underprivileged adolescents. Comparison of diethylpropion hydrochloride with placebo in a double-blind study
-
Andelman MB, Jones C, Nathan S. Treatment of obesity in underprivileged adolescents. Comparison of diethylpropion hydrochloride with placebo in a double-blind study. Clin Pediatr (Phila) 1967; 6: 327-330.
-
(1967)
Clin Pediatr (Phila)
, vol.6
, pp. 327-330
-
-
Andelman, M.B.1
Jones, C.2
Nathan, S.3
-
44
-
-
0018850844
-
Endocrine studies with mazindol in obese patients
-
Dolecek R. Endocrine studies with mazindol in obese patients. Pharmather-apeutica 1980; 2: 309-316.
-
(1980)
Pharmather-apeutica
, vol.2
, pp. 309-316
-
-
Dolecek, R.1
-
45
-
-
17944391462
-
Clinical evaluation of Teronac (mazindol) in the treatment of obesity in children. Part II. Anorectic properties and side effects (author's transl)
-
Golebiowska M, Chlebna-Sokol D, Kobierska I, Konopinska A, Malek M, Mastalska A et al. Clinical evaluation of Teronac (mazindol) in the treatment of obesity in children. Part II. Anorectic properties and side effects (author's transl). Przegl Lek 1981; 38: 355-358.
-
(1981)
Przegl Lek
, vol.38
, pp. 355-358
-
-
Golebiowska, M.1
Chlebna-Sokol, D.2
Kobierska, I.3
Konopinska, A.4
Malek, M.5
Mastalska, A.6
-
46
-
-
17944389899
-
The clin-ical evaluation of teronac (Mazindol) in the treatment of children with obesity. Part I. Effect of the drug on somatic patterns and exercise capacity (author's transl)
-
Golebiowska M, Chlebna-Sokol D, Mastalska A, Zwaigzne-Raczynska J. The clin-ical evaluation of teronac (Mazindol) in the treatment of children with obesity. Part I. Effect of the drug on somatic patterns and exercise capacity (author's transl). Przegl Lek 1981; 38: 311-314.
-
(1981)
Przegl Lek
, vol.38
, pp. 311-314
-
-
Golebiowska, M.1
Chlebna-Sokol, D.2
Mastalska, A.3
Zwaigzne-Raczynska, J.4
-
47
-
-
0020119507
-
Effect of mazindol (teronac) on various hormonal indicators in children with simple obesity
-
Komorowski JM, Zwaigzne-Raczynska J, Owczarczyk I, Golebiowska M, Zarzycki J. Effect of mazindol (teronac) on various hormonal indicators in children with simple obesity. Pediatr Pol 1982; 57: 241-246.
-
(1982)
Pediatr Pol
, vol.57
, pp. 241-246
-
-
Komorowski, J.M.1
Zwaigzne-Raczynska, J.2
Owczarczyk, I.3
Golebiowska, M.4
Zarzycki, J.5
-
48
-
-
0035218082
-
Amphetamine-type central nervous system stimulants release norepinephrine more potently than they releasedopamineand serotonin
-
Rothman RB, Baumann MH, Dersch CM, Romero DV, Rice KC, Carroll FI et al. Amphetamine-type central nervous system stimulants release norepinephrine more potently than they releasedopamineand serotonin.Synapse2001; 39:32-41.
-
(2001)
Synapse
, vol.39
, pp. 32-41
-
-
Rothman, R.B.1
Baumann, M.H.2
Dersch, C.M.3
Romero, D.V.4
Rice, K.C.5
Carroll, F.I.6
-
49
-
-
77349115193
-
Pharmacologic therapies for obesity
-
Kaplan LM. Pharmacologic therapies for obesity. Gastroenterol Clin North Am 2010; 39: 69-79.
-
(2010)
Gastroenterol Clin North Am
, vol.39
, pp. 69-79
-
-
Kaplan, L.M.1
-
50
-
-
0033600538
-
Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates Implications for primary pulmonary hypertension
-
Rothman RB, Ayestas MA, Dersch CM, Baumann MH. Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. Circulation 1999; 100: 869-875.
-
(1999)
Circulation
, vol.100
, pp. 869-875
-
-
Rothman, R.B.1
Ayestas, M.A.2
Dersch, C.M.3
Baumann, M.H.4
-
51
-
-
84872120963
-
-
Drug Enforcement Administration Office Of Diversion Control. List Of Scheduling Actions Controlled Substances Regulated Chemicals U.S. Department of Justice Accessed: 1 February 2012
-
Drug Enforcement Administration, Office of Diversion Control. List of scheduling actions controlled substances regulated chemicals, U.S. Department of Justice. http://www.deadiversion.usdoj.gov/schedules/index.html. Accessed: 1 February 2012.
-
-
-
-
52
-
-
0020428901
-
Three controlled trials of weight loss with phenylpropanolamine
-
Altschuler S, Conte A, Sebok M, Marlin RL, Winick C. Three controlled trials of weight loss with phenylpropanolamine. Int J Obes 1982; 6: 549-556.
-
(1982)
Int J Obes
, vol.6
, pp. 549-556
-
-
Altschuler, S.1
Conte, A.2
Sebok, M.3
Marlin, R.L.4
Winick, C.5
-
53
-
-
0034700436
-
Phe-nylpropanolamine and the risk of hemorrhagic stroke
-
Kernan WN, Viscoli CM, Brass LM, Broderick JP, Brott T, Feldmann E et al. Phe-nylpropanolamine and the risk of hemorrhagic stroke. N Engl J Med 2000; 343: 1826-1832.
-
(2000)
N Engl J Med
, vol.343
, pp. 1826-1832
-
-
Kernan, W.N.1
Viscoli, C.M.2
Brass, L.M.3
Broderick, J.P.4
Brott, T.5
Feldmann, E.6
-
54
-
-
0034850565
-
Thyroid function in men taking carbamazepine, oxcarbazepine, or valproate for epilepsy
-
Isojarvi JI, Turkka J, Pakarinen AJ, Kotila M, Rattya J, Myllyla VV. Thyroid function in men taking carbamazepine, oxcarbazepine, or valproate for epilepsy. Epilepsia 2001; 42: 930-934.
-
(2001)
Epilepsia
, vol.42
, pp. 930-934
-
-
Isojarvi, J.I.1
Turkka, J.2
Pakarinen, A.J.3
Kotila, M.4
Rattya, J.5
Myllyla, V.V.6
-
55
-
-
84862023939
-
Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c m RNA but not for feeding-dependent expression
-
Haas JT, Miao J, Chanda D, Wang Y, Zhao E, Haas ME et al. Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c m RNA but not for feeding-dependent expression. Cell Metab 2012; 15: 873-884.
-
(2012)
Cell Metab
, vol.15
, pp. 873-884
-
-
Haas, J.T.1
Miao, J.2
Chanda, D.3
Wang, Y.4
Zhao, E.5
Haas, M.E.6
-
56
-
-
84906416668
-
Obesity in childhood. Acontrolled trial ofanorectic drugs
-
Lorber J. Obesity in childhood. Acontrolled trial ofanorectic drugs.Arch Dis Child 1966; 41: 309-312.
-
(1966)
Arch Dis Child
, vol.41
, pp. 309-312
-
-
Lorber, J.1
-
57
-
-
0014783328
-
Tenuate dospan as an appetitie suppressant in the treatment of obese children
-
Stewart DA, Bailey JD, Patell H. Tenuate dospan as an appetitie suppressant in the treatment of obese children. Appl Ther 1970; 12: 34-36.
-
(1970)
Appl Ther
, vol.12
, pp. 34-36
-
-
Stewart, D.A.1
Bailey, J.D.2
Patell, H.3
-
58
-
-
0030137862
-
Effi-cacy and safety of dexfenfluramine treatment in obese adolescents
-
Malecka-Tendera E, Koehler B, Muchacka M, Wazowski R, Trzciakowska A. Effi-cacy and safety of dexfenfluramine treatment in obese adolescents. Pediatr Pol 1996; 71: 431-436.
-
(1996)
Pediatr Pol
, vol.71
, pp. 431-436
-
-
Malecka-Tendera, E.1
Koehler, B.2
Muchacka, M.3
Wazowski, R.4
Trzciakowska, A.5
-
59
-
-
0014184304
-
A clinical trial offenfluramine in obese children
-
Bacon GE, Lowrey GH. A clinical trial offenfluramine in obese children. Curr Ther Res Clin Exp 1967; 9: 626-630.
-
(1967)
Curr Ther Res Clin Exp
, vol.9
, pp. 626-630
-
-
Bacon, G.E.1
Lowrey, G.H.2
-
60
-
-
0028222739
-
Fluoxetine: A randomized clinical trial in the treatment of obesity
-
Goldstein DJ, Rampey Jr. AH, Enas GG, Potvin JH, Fludzinski LA, Levine LR. Fluoxetine: a randomized clinical trial in the treatment of obesity. Int JObes Relat Metab Disord 1994; 18: 129-135.
-
(1994)
Int JObes Relat Metab Disord
, vol.18
, pp. 129-135
-
-
Goldstein, D.J.1
Rampey Jr., A.H.2
Enas, G.G.3
Potvin, J.H.4
Fludzinski, L.A.5
Levine, L.R.6
-
61
-
-
0002323687
-
Is DL-fenfluramine a poten-tially helpful drug therapy in overweight adolescent subjects?
-
Pedrinola F, Cavaliere H, Lima N, Medeiros-Neto G. Is DL-fenfluramine a poten-tially helpful drug therapy in overweight adolescent subjects? Obes Res 1994; 2: 1-4.
-
(1994)
Obes Res
, vol.2
, pp. 1-4
-
-
Pedrinola, F.1
Cavaliere, H.2
Lima, N.3
Medeiros-Neto, G.4
-
62
-
-
0030278088
-
The addition of dexfenfluramine to fluoxetine in the treatment of obesity: A randomized clinical trial
-
Pedrinola F, Sztejnsznajd C, Lima N, Halpern A, Medeiros-Neto G. The addition of dexfenfluramine to fluoxetine in the treatment of obesity: a randomized clinical trial. Obes Res 1996; 4: 549-554.
-
(1996)
Obes Res
, vol.4
, pp. 549-554
-
-
Pedrinola, F.1
Sztejnsznajd, C.2
Lima, N.3
Halpern, A.4
Medeiros-Neto, G.5
-
63
-
-
0014265033
-
Chlorphentermine as an anorexigenic agent in adolescent obesity. Report of its efficacy in a double-blind study of 30 teen-agers
-
Rauh JL, Lipp R. Chlorphentermine as an anorexigenic agent in adolescent obesity. Report of its efficacy in a double-blind study of 30 teen-agers. Clin Pediatr (Phila) 1968; 7: 138-140.
-
(1968)
Clin Pediatr (Phila)
, vol.7
, pp. 138-140
-
-
Rauh, J.L.1
Lipp, R.2
-
64
-
-
0031567756
-
-
Anon. Cardiac Valvulopathy Associated With Exposure To Fenfluramine Or Dex-fenfluramine: U.S. Department of Health and Human Services interim public health recommendations, November 1997
-
Anon. Cardiac valvulopathy associated with exposure to fenfluramine or dex-fenfluramine: U.S. Department of Health and Human Services interim public health recommendations, November 1997. MMWR Morb Mortal Wkly Rep 1997; 46: 1061-1066.
-
(1997)
MMWR Morb Mortal Wkly Rep
, vol.46
, pp. 1061-1066
-
-
-
65
-
-
0030876952
-
Valvular heart disease associated with fenfluramine-phentermine
-
Connolly HM, Crary JL, Mc Goon MD, Hensrud DD, Edwards BS, Edwards WD et al. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med 1997; 337: 581-588.
-
(1997)
N Engl J Med
, vol.337
, pp. 581-588
-
-
Connolly, H.M.1
Crary, J.L.2
Mc Goon, M.D.3
Hensrud, D.D.4
Edwards, B.S.5
Edwards, W.D.6
-
66
-
-
9444287592
-
Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International Primary Pulmonary Hypertension Study Group
-
Abenhaim L, Moride Y, Brenot F, Rich S, Benichou J, Kurz X et al. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International Primary Pulmonary Hypertension Study Group. N Engl J Med 1996; 335: 609-616.
-
(1996)
N Engl J Med
, vol.335
, pp. 609-616
-
-
Abenhaim, L.1
Moride, Y.2
Brenot, F.3
Rich, S.4
Benichou, J.5
Kurz, X.6
-
67
-
-
0021242404
-
A double-blind clinical trial in weight control. Use offenfluramine and phentermine alone and in combi-nation
-
Weintraub M, Hasday JD, Mushlin AI, Lockwood DH. A double-blind clinical trial in weight control. Use offenfluramine and phentermine alone and in combi-nation. Arch Intern Med 1984; 144: 1143-1148.
-
(1984)
Arch Intern Med
, vol.144
, pp. 1143-1148
-
-
Weintraub, M.1
Hasday, J.D.2
Mushlin, A.I.3
Lockwood, D.H.4
-
68
-
-
0036766420
-
The use of dextroamphetamine to treat obesity and hyperphagia in children treated for craniopharyngioma
-
Mason PW, Krawiecki N, Meacham LR. The use of dextroamphetamine to treat obesity and hyperphagia in children treated for craniopharyngioma. Arch Pediatr Adolesc Med 2002; 156: 887-892.
-
(2002)
Arch Pediatr Adolesc Med
, vol.156
, pp. 887-892
-
-
Mason, P.W.1
Krawiecki, N.2
Meacham, L.R.3
-
69
-
-
84872108548
-
The suppression ofappetite and food consumption by methylphenidate: The moderating effects of gender and weight status in healthy adults
-
Davis C, Fattore L, Kaplan AS, Carter JC, Levitan RD, Kennedy JL. The suppression ofappetite and food consumption by methylphenidate: the moderating effects of gender and weight status in healthy adults. Int J Neuropsychopharmacol 2011 1-7.
-
Int J Neuropsychopharmacol
, vol.2011
, pp. 1-7
-
-
Davis, C.1
Fattore, L.2
Kaplan, A.S.3
Carter, J.C.4
Levitan, R.D.5
Kennedy, J.L.6
-
70
-
-
16744362910
-
A double-blind, placebo-controlled study of modified-release methylphenidate in children with attention-deficit/hyper-activity disorder
-
Greenhill LL, Findling RL, Swanson JM. A double-blind, placebo-controlled study of modified-release methylphenidate in children with attention-deficit/ hyper-activity disorder. Pediatrics 2002; 109: E39.
-
(2002)
Pediatrics
, vol.109
-
-
Greenhill, L.L.1
Findling, R.L.2
Swanson, J.M.3
-
71
-
-
33750498069
-
Safety and tolerability of methylphenidate in preschool children with ADHD
-
Wigal T, Greenhill L, Chuang S, Mc Gough J, Vitiello B, Skrobala A et al. Safety and tolerability of methylphenidate in preschool children with ADHD. J Am Acad Child Adolesc Psychiatry 2006; 45: 1294-1303.
-
(2006)
J Am Acad Child Adolesc Psychiatry
, vol.45
, pp. 1294-1303
-
-
Wigal, T.1
Greenhill, L.2
Chuang, S.3
Mc Gough, J.4
Vitiello, B.5
Skrobala, A.6
-
72
-
-
0036123886
-
Abuse and toxicity of methylphenidate
-
Klein-Schwartz W. Abuse and toxicity of methylphenidate. Curr Opin Pediatr 2002; 14: 219-223.
-
(2002)
Curr Opin Pediatr
, vol.14
, pp. 219-223
-
-
Klein-Schwartz, W.1
-
73
-
-
84857425784
-
Pharmacotherapies for obesity: Past, current, and future therapies
-
Ioannides-Demos LL, Piccenna L, Mc Neil JJ. Pharmacotherapies for obesity: past, current, and future therapies. J Obes 2011 2011 179674.
-
J Obes
, vol.2011
, Issue.2011
, pp. 179674
-
-
Ioannides-Demos, L.L.1
Piccenna, L.2
Mc Neil, J.J.3
-
74
-
-
70350210505
-
Pharmacotherapy in pediatric obesity: Current agents and future directions
-
Wald AB, Uli NK. Pharmacotherapy in pediatric obesity: current agents and future directions. Rev Endocr Metab Disord 2009; 10: 205-214.
-
(2009)
Rev Endocr Metab Disord
, vol.10
, pp. 205-214
-
-
Wald, A.B.1
Uli, N.K.2
-
76
-
-
20144389757
-
Treat-ment of obese adolescents with sibutramine: A randomized, double-blind, controlled study
-
Godoy-Matos A, Carraro L, Vieira A, Oliveira J, Guedes EP, Mattos L et al. Treat-ment of obese adolescents with sibutramine: a randomized, double-blind, controlled study. J Clin Endocrinol Metab 2005; 90: 1460-1465.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 1460-1465
-
-
Godoy-Matos, A.1
Carraro, L.2
Vieira, A.3
Oliveira, J.4
Guedes, E.P.5
Mattos, L.6
-
77
-
-
33645024991
-
Use of sibutramine in Obese Hispanic Adolescents
-
Violante-Ortiz R, Del-Rio-Navarro BE, Lara-Esqueda A, Perez P, Fanghanel G, Madero Aetal. Use of sibutramine in obese Hispanic adolescents. Adv Ther2005; 22: 642-649.
-
(2005)
Adv Ther
, vol.22
, pp. 642-649
-
-
Violante-Ortiz, R.1
Del-Rio-Navarro, B.E.2
Lara-Esqueda, A.3
Perez, P.4
Fanghanel, G.5
Madero, A.6
-
78
-
-
33746664768
-
Effects of sibutramine treatment in obese adolescents: A randomized trial
-
Berkowitz RI, Fujioka K, Daniels SR, Hoppin AG, Owen S, Perry AC et al. Effects of sibutramine treatment in obese adolescents: a randomized trial. Ann Intern Med 2006; 145: 81-90.
-
(2006)
Ann Intern Med
, vol.145
, pp. 81-90
-
-
Berkowitz, R.I.1
Fujioka, K.2
Daniels, S.R.3
Hoppin, A.G.4
Owen, S.5
Perry, A.C.6
-
79
-
-
33746803704
-
Use of sibutramine in obese mexican adolescents: A 6-month, randomized, double-blind, placebo-controlled, parallel-group trial
-
Garcia-Morales LM, Berber A, Macias-Lara CC, Lucio-Ortiz C, Del-Rio-Navarro BE, Dorantes-Alvarez LM. Use of sibutramine in obese mexican adolescents: a 6-month, randomized, double-blind, placebo-controlled, parallel-group trial. Clin Ther 2006; 28: 770-782.
-
(2006)
Clin Ther
, vol.28
, pp. 770-782
-
-
Garcia-Morales, L.M.1
Berber, A.2
MacIas-Lara, C.C.3
Lucio-Ortiz, C.4
Del-Rio-Navarro, B.E.5
Dorantes-Alvarez, L.M.6
-
80
-
-
30944440108
-
Sibutramine as an adjuvant therapy in adolescents suffering from morbid obesity
-
Reisler G, Tauber T, Afriat R, Bortnik O, Goldman M. Sibutramine as an adjuvant therapy in adolescents suffering from morbid obesity. Isr Med Assoc J 2006; 8: 30-32.
-
(2006)
Isr Med Assoc J
, vol.8
, pp. 30-32
-
-
Reisler, G.1
Tauber, T.2
Afriat, R.3
Bortnik, O.4
Goldman, M.5
-
81
-
-
34250863948
-
Weight loss in obese African American and Caucasian adolescents: Secondary analysis of a randomized clinical trial of behavioral therapy plus sibutramine
-
Budd GM, Hayman LL, Crump E, Pollydore C, Hawley KD, Cronquist JL et al. Weight loss in obese African American and Caucasian adolescents: secondary analysis of a randomized clinical trial of behavioral therapy plus sibutramine. J Cardiovasc Nurs 2007; 22: 288-296.
-
(2007)
J Cardiovasc Nurs
, vol.22
, pp. 288-296
-
-
Budd, G.M.1
Hayman, L.L.2
Crump, E.3
Pollydore, C.4
Hawley, K.D.5
Cronquist, J.L.6
-
82
-
-
34447126288
-
Car-diovascular effects of sibutramine in the treatment ofobese adolescents: Results of a randomized, double-blind, placebo-controlled study
-
Daniels SR, Long B, Crow S, Styne D, Sothern M, Vargas-Rodriguez I et al. Car-diovascular effects of sibutramine in the treatment ofobese adolescents: results of a randomized, double-blind, placebo-controlled study. Pediatrics 2007; 120: e147-e157.
-
(2007)
Pediatrics
, vol.120
-
-
Daniels, S.R.1
Long, B.2
Crow, S.3
Styne, D.4
Sothern, M.5
Vargas-Rodriguez, I.6
-
83
-
-
35948962283
-
Impact sibutramine therapy in children with hypothalamic obesity or obesity with aggravating syndromes
-
Danielsson P, Janson A, Norgren S, Marcus C. Impact sibutramine therapy in children with hypothalamic obesity or obesity with aggravating syndromes. J Clin Endocrinol Metab 2007; 92: 4101-4106.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 4101-4106
-
-
Danielsson, P.1
Janson, A.2
Norgren, S.3
Marcus, C.4
-
84
-
-
34147147143
-
The effect of sibutramine on energy expenditure and body compo-sition in obese adolescents
-
Van Mil EG, Westerterp KR, Kester AD, Delemarre-van de Waal HA, Gerver WJ, Saris WH. The effect of sibutramine on energy expenditure and body compo-sition in obese adolescents. J Clin Endocrinol Metab 2007; 92: 1409-1414.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1409-1414
-
-
Van Mil, E.G.1
Westerterp, K.R.2
Kester, A.D.3
Delemarre-Van De Waal, H.A.4
Gerver, W.J.5
Saris, W.H.6
-
85
-
-
84872103912
-
Behavior therapy and sibutramine for the treatment of adolescent obesity
-
Yanovski JA. Behavior therapy and sibutramine for the treatment of adolescent obesity. J Pediatr 2003; 143: 686.
-
(2003)
J Pediatr
, vol.143
, pp. 686
-
-
Yanovski, J.A.1
-
86
-
-
0036736799
-
Recent developments in the treatment of obesity-related hypertension
-
Pischon T, Sharma AM. Recent developments in the treatment of obesity-related hypertension. Curr Opin Nephrol Hypertens 2002; 11: 497-502.
-
(2002)
Curr Opin Nephrol Hypertens
, vol.11
, pp. 497-502
-
-
Pischon, T.1
Sharma, A.M.2
-
87
-
-
36849095595
-
Cardiovascular responses to weight management and sibutramine in high-risk subjects: An analysis from the SCOUT trial
-
Torp-Pedersen C, Caterson I, Coutinho W, Finer N, Van Gaal L, Maggioni A et al. Cardiovascular responses to weight management and sibutramine in high-risk subjects: an analysis from the SCOUT trial. Eur Heart J 2007; 28: 2915-2923.
-
(2007)
Eur Heart J
, vol.28
, pp. 2915-2923
-
-
Torp-Pedersen, C.1
Caterson, I.2
Coutinho, W.3
Finer, N.4
Van Gaal, L.5
Maggioni, A.6
-
88
-
-
77956284607
-
Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects
-
James WP, Caterson ID, Coutinho W, Finer N, Van Gaal LF, Maggioni AP et al. Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N Engl J Med 2010; 363: 905-917.
-
(2010)
N Engl J Med
, vol.363
, pp. 905-917
-
-
James, W.P.1
Caterson, I.D.2
Coutinho, W.3
Finer, N.4
Van Gaal, L.F.5
Maggioni, A.P.6
-
91
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
92
-
-
0036177867
-
Control of energy homeostasis and insulin action by adipocyte hor-mones: Leptin, acylation stimulating protein, and adiponectin
-
Havel PJ. Control of energy homeostasis and insulin action by adipocyte hor-mones: leptin, acylation stimulating protein, and adiponectin. Curr Opin Lipidol 2002; 13: 51-59.
-
(2002)
Curr Opin Lipidol
, vol.13
, pp. 51-59
-
-
Havel, P.J.1
-
93
-
-
0033009882
-
High-fat meals reduce 24-h circulating leptin concentrations in women
-
Havel PJ, Townsend R, Chaump L, Teff K. High-fat meals reduce 24-h circulating leptin concentrations in women. Diabetes 1999; 48: 334-341.
-
(1999)
Diabetes
, vol.48
, pp. 334-341
-
-
Havel, P.J.1
Townsend, R.2
Chaump, L.3
Teff, K.4
-
94
-
-
0038699005
-
Roles of leptin and ghrelin in the loss of body weight caused by a low fat, high carbohydrate diet
-
Weigle DS, Cummings DE, Newby PD, Breen PA, Frayo RS, Matthys CC etal. Roles of leptin and ghrelin in the loss of body weight caused by a low fat, high carbohydrate diet. J Clin Endocrinol Metab 2003; 88: 1577-1586.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 1577-1586
-
-
Weigle, D.S.1
Cummings, D.E.2
Newby, P.D.3
Breen, P.A.4
Frayo, R.S.5
Matthys, C.C.6
-
95
-
-
4544286790
-
Effects of exogenous leptin on satiety and satiation in patients with lipodystrophy and leptin insufficiency
-
Mc Duffie JR, Riggs PA, Calis KA, Freedman RJ, Oral EA, De Paoli AM et al. Effects of exogenous leptin on satiety and satiation in patients with lipodystrophy and leptin insufficiency. J Clin Endocrinol Metab 2004; 89: 4258-4263.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 4258-4263
-
-
Mc Duffie, J.R.1
Riggs, P.A.2
Calis, K.A.3
Freedman, R.J.4
Oral, E.A.5
De Paoli, A.M.6
-
96
-
-
0035757975
-
Brain pathways controlling food intake and body weight
-
Schwartz MW. Brain pathways controlling food intake and body weight. Exp Biol Med (Maywood) 2001; 226: 978-981.
-
(2001)
Exp Biol Med (Maywood)
, vol.226
, pp. 978-981
-
-
Schwartz, M.W.1
-
97
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D et al. Weight-reducing effects of the plasma protein encoded by the obese gene. Science 1995; 269: 543-546.
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
-
98
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T et al. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 1995; 269: 540-543.
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
Hecht, R.4
Winters, D.5
Boone, T.6
-
99
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks [see comments]
-
Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks [see comments]. Science 1995; 269: 546-549.
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
100
-
-
0033575993
-
Effects ofrecombinant leptin therapy in a child with congenital leptin deficiency
-
Farooqi IS, Jebb SA, Langmack G, Lawrence E, Cheetham CH, Prentice AM et al. Effects ofrecombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med 1999; 341: 879-884.
-
(1999)
N Engl J Med
, vol.341
, pp. 879-884
-
-
Farooqi, I.S.1
Jebb, S.A.2
Langmack, G.3
Lawrence, E.4
Cheetham, C.H.5
Prentice, A.M.6
-
101
-
-
0036800760
-
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
-
Farooqi IS, Matarese G, Lord GM, Keogh JM, Lawrence E, Agwu C et al. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 2002; 110: 1093-1103.
-
(2002)
J Clin Invest
, vol.110
, pp. 1093-1103
-
-
Farooqi, I.S.1
Matarese, G.2
Lord, G.M.3
Keogh, J.M.4
Lawrence, E.5
Agwu, C.6
-
102
-
-
6344221594
-
Congenital leptin deficiency due to homozygosity for the Delta133G mutation: Reportofanother caseand evaluation ofresponse tofouryears of leptin therapy
-
Gibson WT, Farooqi IS, Moreau M, De Paoli AM, Lawrence E, O'Rahilly S et al. Congenital leptin deficiency due to homozygosity for the Delta133G mutation: reportofanother caseand evaluation ofresponse tofouryears of leptin therapy. J Clin Endocrinol Metab 2004; 89: 4821-4826.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 4821-4826
-
-
Gibson, W.T.1
Farooqi, I.S.2
Moreau, M.3
De Paoli, A.M.4
Lawrence, E.5
O'Rahilly, S.6
-
104
-
-
72449185147
-
Efficacy of leptin therapy in the different forms of human lipodystrophy
-
Chong AY, Lupsa BC, Cochran EK, Gorden P. Efficacy of leptin therapy in the different forms of human lipodystrophy. Diabetologia 2010; 53: 27-35.
-
(2010)
Diabetologia
, vol.53
, pp. 27-35
-
-
Chong, A.Y.1
Lupsa, B.C.2
Cochran, E.K.3
Gorden, P.4
-
105
-
-
79955620729
-
Leptin is an effective treatment for hypothalamic amenorrhea
-
Chou SH, Chamberland JP, Liu X, Matarese G, Gao C, Stefanakis R et al. Leptin is an effective treatment for hypothalamic amenorrhea. Proc Natl Acad Sci USA 2011; 108: 6585-6590.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 6585-6590
-
-
Chou, S.H.1
Chamberland, J.P.2
Liu, X.3
Matarese, G.4
Gao, C.5
Stefanakis, R.6
-
106
-
-
0032747280
-
Recombinant leptin for weight loss in obese and lean adults: A randomized, controlled, dose-escalation trial
-
Heymsfield SB, Greenberg AS, Fujioka K, Dixon RM, Kushner R, Hunt T et al. Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial. JAMA 1999; 282: 1568-1575.
-
(1999)
JAMA
, vol.282
, pp. 1568-1575
-
-
Heymsfield, S.B.1
Greenberg, A.S.2
Fujioka, K.3
Dixon, R.M.4
Kushner, R.5
Hunt, T.6
-
107
-
-
79959409408
-
Efficacy of metreleptin in obese patients with type 2 diabetes: Cellular and molecular pathways underlying leptin tolerance
-
Moon HS, Matarese G, Brennan AM, Chamberland JP, Liu X, Fiorenza CG et al. Efficacy of metreleptin in obese patients with type 2 diabetes: cellular and molecular pathways underlying leptin tolerance. Diabetes 2011; 60: 1647-1656.
-
(2011)
Diabetes
, vol.60
, pp. 1647-1656
-
-
Moon, H.S.1
Matarese, G.2
Brennan, A.M.3
Chamberland, J.P.4
Liu, X.5
Fiorenza, C.G.6
-
108
-
-
0036093071
-
Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones
-
Rosenbaum M, Murphy EM, Heymsfield SB, Matthews DE, Leibel RL. Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones. J Clin Endo-crinol Metab 2002; 87: 2391-2394.
-
(2002)
J Clin Endo-crinol Metab
, vol.87
, pp. 2391-2394
-
-
Rosenbaum, M.1
Murphy, E.M.2
Heymsfield, S.B.3
Matthews, D.E.4
Leibel, R.L.5
-
109
-
-
31044444463
-
Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight
-
Rosenbaum M, Goldsmith R, Bloomfield D, Magnano A, Weimer L, Heymsfield S et al. Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight. J Clin Invest 2005; 115: 3579-3586.
-
(2005)
J Clin Invest
, vol.115
, pp. 3579-3586
-
-
Rosenbaum, M.1
Goldsmith, R.2
Bloomfield, D.3
Magnano, A.4
Weimer, L.5
Heymsfield, S.6
-
110
-
-
46749099010
-
Leptin reverses weight loss-induced changes in regional neural activity responses to visual food stimuli
-
Rosenbaum M, Sy M, Pavlovich K, Leibel RL, Hirsch J. Leptin reverses weight loss-induced changes in regional neural activity responses to visual food stimuli. J Clin Invest 2008; 118: 2583-2591.
-
(2008)
J Clin Invest
, vol.118
, pp. 2583-2591
-
-
Rosenbaum, M.1
Sy, M.2
Pavlovich, K.3
Leibel, R.L.4
Hirsch, J.5
-
111
-
-
73549111308
-
Effects of experimental weight perturbation on skeletal muscle work efficiency, fuel utilization, and biochemistry in human subjects
-
Goldsmith R, Joanisse DR, Gallagher D, Pavlovich K, Shamoon E, Leibel RL et al. Effects of experimental weight perturbation on skeletal muscle work efficiency, fuel utilization, and biochemistry in human subjects. Am J Physiol Regul Integr Comp Physiol 2010; 298: R79-R88.
-
(2010)
Am J Physiol Regul Integr Comp Physiol
, vol.298
-
-
Goldsmith, R.1
Joanisse, D.R.2
Gallagher, D.3
Pavlovich, K.4
Shamoon, E.5
Leibel, R.L.6
-
112
-
-
80155151300
-
Effects of weight loss and leptin on skeletal muscle in human subjects
-
Baldwin KM, Joanisse DR, Haddad F, Goldsmith RL, Gallagher D, Pavlovich KH etal. Effects of Weight Loss and Leptin on Skeletal Muscle in Human Subjects. Am J Physiol Regul Integr Comp Physiol 2011; 301: R1259-R1266.
-
(2011)
Am J Physiol Regul Integr Comp Physiol
, vol.301
-
-
Baldwin, K.M.1
Joanisse, D.R.2
Haddad, F.3
Goldsmith, R.L.4
Gallagher, D.5
Pavlovich, K.H.6
-
113
-
-
0036636368
-
Bupropion SR enhances weight loss: A 48-week double-blind, placebo- con-trolled trial
-
Anderson JW, Greenway FL, Fujioka K, Gadde KM, Mc Kenney J, O'Neil PM. Bupropion SR enhances weight loss: a 48-week double-blind, placebo- con-trolled trial. Obes Res 2002; 10: 633-641.
-
(2002)
Obes Res
, vol.10
, pp. 633-641
-
-
Anderson, J.W.1
Greenway, F.L.2
Fujioka, K.3
Gadde, K.M.4
Mc Kenney, J.5
O'Neil, P.M.6
-
114
-
-
33947232740
-
Inhibition of dopamine and norepinephrine reuptake produces additive effects on energy balance in lean and obese mice
-
Billes SK, Cowley MA. Inhibition of dopamine and norepinephrine reuptake produces additive effects on energy balance in lean and obese mice. Neu-ropsychopharmacology 2007; 32: 822-834.
-
(2007)
Neu-ropsychopharmacology
, vol.32
, pp. 822-834
-
-
Billes, S.K.1
Cowley, M.A.2
-
115
-
-
15944367788
-
Meta-analysis: Pharmacologic treatment of obesity
-
Li Z, Maglione M, Tu W, Mojica W, Arterburn D, Shugarman LR et al. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med 2005; 142: 532-546.
-
(2005)
Ann Intern Med
, vol.142
, pp. 532-546
-
-
Li, Z.1
Maglione, M.2
Tu, W.3
Mojica, W.4
Arterburn, D.5
Shugarman, L.R.6
-
116
-
-
0036778351
-
Bupropion SR vs. placebo for weight loss in obese patients with depressive symptoms
-
Jain AK, Kaplan RA, Gadde KM, Wadden TA, Allison DB, Brewer ER et al. Bupropion SR vs. placebo for weight loss in obese patients with depressive symptoms. Obes Res 2002; 10: 1049-1056.
-
(2002)
Obes Res
, vol.10
, pp. 1049-1056
-
-
Jain, A.K.1
Kaplan, R.A.2
Gadde, K.M.3
Wadden, T.A.4
Allison, D.B.5
Brewer, E.R.6
-
117
-
-
0642334310
-
Open trial of bupropion SR in adolescent major depression
-
Glod CA, Lynch A, Flynn E, Berkowitz C, Baldessarini RJ. Open trial of bupropion SR in adolescent major depression. J Child Adolesc Psychiatr Nurs 2003; 16: 123-130.
-
(2003)
J Child Adolesc Psychiatr Nurs
, vol.16
, pp. 123-130
-
-
Glod, C.A.1
Lynch, A.2
Flynn, E.3
Berkowitz, C.4
Baldessarini, R.J.5
-
118
-
-
25644460463
-
Weight changes in teens on psychotropic medication combinations at Austin State Hospital
-
Becker EA, Shafer A, Anderson R. Weight changes in teens on psychotropic medication combinations at Austin State Hospital. Tex Med 2005; 101: 62-70.
-
(2005)
Tex Med
, vol.101
, pp. 62-70
-
-
Becker, E.A.1
Shafer, A.2
Anderson, R.3
-
119
-
-
79952297237
-
Lorcaserin, a 5-HT(2C) receptor agonist, reduces body weight by decreasing energy intake without influencing energy expenditure
-
Martin CK, Redman LM, Zhang J, Sanchez M, Anderson CM, Smith SR et al. Lorcaserin, a 5-HT(2C) receptor agonist, reduces body weight by decreasing energy intake without influencing energy expenditure. J Clin Endocrinol Metab 2011; 96: 837-845.
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 837-845
-
-
Martin, C.K.1
Redman, L.M.2
Zhang, J.3
Sanchez, M.4
Anderson, C.M.5
Smith, S.R.6
-
120
-
-
77954635020
-
Multicenter, placebo-controlled trial of lorcaserin for weight management
-
Smith SR, Weissman NJ, Anderson CM, Sanchez M, Chuang E, Stubbe S et al. Multicenter, placebo-controlled trial of lorcaserin for weight management. N Engl J Med 2010; 363: 245-256.
-
(2010)
N Engl J Med
, vol.363
, pp. 245-256
-
-
Smith, S.R.1
Weissman, N.J.2
Anderson, C.M.3
Sanchez, M.4
Chuang, E.5
Stubbe, S.6
-
121
-
-
80053539943
-
A one-year randomized trial of lorcaserin for weight loss in obese and over-weight adults: The BLOSSOM trial
-
Fidler MC, Sanchez M, Raether B, Weissman NJ, Smith SR, Shanahan WR et al. A one-year randomized trial of lorcaserin for weight loss in obese and over-weight adults: the BLOSSOM trial. J Clin Endocrinol Metab 2011; 96: 3067-3077.
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 3067-3077
-
-
Fidler, M.C.1
Sanchez, M.2
Raether, B.3
Weissman, N.J.4
Smith, S.R.5
Shanahan, W.R.6
-
122
-
-
84862869642
-
Rando-mized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 dia-betes mellitus: The BLOOM-DM study
-
O'Neil PM, Smith SR, Weissman NJ, Fidler MC, Sanchez M, Zhang J et al. Rando-mized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 dia-betes mellitus: the BLOOM-DM study. Obesity (Silver Spring) 2012; 20: 1426-1436.
-
(2012)
Obesity (Silver Spring)
, vol.20
, pp. 1426-1436
-
-
O'Neil, P.M.1
Smith, S.R.2
Weissman, N.J.3
Fidler, M.C.4
Sanchez, M.5
Zhang, J.6
-
125
-
-
56649112848
-
Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: A randomised, double-blind, placebo-controlled trial
-
Astrup A, Madsbad S, Breum L, Jensen TJ, Kroustrup JP, Larsen TM. Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial. Lancet 2008; 372: 1906-1913.
-
(2008)
Lancet
, vol.372
, pp. 1906-1913
-
-
Astrup, A.1
Madsbad, S.2
Breum, L.3
Jensen, T.J.4
Kroustrup, J.P.5
Larsen, T.M.6
-
126
-
-
84857686801
-
The effect of tesofensine on appetite sensations
-
Gilbert JA, Gasteyger C, Raben A, Meier DH, Astrup A, Sjodin A. The effect of tesofensine on appetite sensations. Obesity 2012; 20: 553-561.
-
(2012)
Obesity
, vol.20
, pp. 553-561
-
-
Gilbert, J.A.1
Gasteyger, C.2
Raben, A.3
Meier, D.H.4
Astrup, A.5
Sjodin, A.6
-
127
-
-
78349310073
-
The effect of the triple monoamine reuptake inhibitor tesofensine on energy metabolism and appetite in overweight and moderately obese men
-
Sjodin A, Gasteyger C, Nielsen AL, Raben A, Mikkelsen JD, Jensen JK et al. The effect of the triple monoamine reuptake inhibitor tesofensine on energy metabolism and appetite in overweight and moderately obese men. Int J Obes (Lond) 2010; 34: 1634-1643.
-
(2010)
Int J Obes (Lond)
, vol.34
, pp. 1634-1643
-
-
Sjodin, A.1
Gasteyger, C.2
Nielsen, A.L.3
Raben, A.4
Mikkelsen, J.D.5
Jensen, J.K.6
-
128
-
-
36048995288
-
Efficacy and safety of the weight-loss drug rimonabant: A meta-analysis ofrandomised trials
-
Christensen R, Kristensen PK, Bartels EM, Bliddal H, Astrup A. Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis ofrandomised trials. Lancet 2007; 370: 1706-1713.
-
(2007)
Lancet
, vol.370
, pp. 1706-1713
-
-
Christensen, R.1
Kristensen, P.K.2
Bartels, E.M.3
Bliddal, H.4
Astrup, A.5
-
129
-
-
41149130137
-
Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in over-weight/obese patients: Pooled 1-year data from the Rimonabant in Obesity (RIO) program
-
Van Gaal L, Pi-Sunyer X, Despres JP, Mc Carthy C, Scheen A. Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in over-weight/obese patients: pooled 1-year data from the Rimonabant in Obesity (RIO) program. Diabetes Care 2008; 31(Suppl 2): S229-S240.
-
(2008)
Diabetes Care
, vol.31
, Issue.SUPPL. 2
-
-
Van Gaal, L.1
Pi-Sunyer, X.2
Despres, J.P.3
Mc Carthy, C.4
Scheen, A.5
-
130
-
-
84872107496
-
-
US Food and Drug Administration Briefing Document -NDA 21-888. May 20, 2007 Accessed: 30 March 2012
-
US Food and Drug Administration. Endocrine and Metabolic Drugs Advisory Committee Meeting. Sanofi Aventis: Zimulti (Rimonabant) Briefing Document -NDA 21-888. May 20, 2007. http://www.scribd.com/doc/1117189/US-Food-and-Drug- Administration-20074306b101sponsorbackgrounder. Accessed: 30 March 2012.
-
Endocrine and Metabolic Drugs Advisory Committee Meeting. Sanofi Aventis: Zimulti (Rimonabant)
-
-
-
132
-
-
70849120492
-
Regulatory challenges for new drugs to treat obesity and comorbid metabolic disorders
-
Heal DJ, Gosden J, Smith SL. Regulatory challenges for new drugs to treat obesity and comorbid metabolic disorders. Br J Clin Pharmacol 2009; 68: 861-874.
-
(2009)
Br J Clin Pharmacol
, vol.68
, pp. 861-874
-
-
Heal, D.J.1
Gosden, J.2
Smith, S.L.3
-
133
-
-
77952923643
-
Obesity: Taranabant no longer developed as an antiobesity agent
-
Koch L. Obesity: Taranabant no longer developed as an antiobesity agent. Nat Rev Endocrinol 2010; 6: 300.
-
(2010)
Nat Rev Endocrinol
, vol.6
, pp. 300
-
-
Koch, L.1
-
134
-
-
51349153318
-
Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice
-
Osei-Hyiaman D, Liu J, Zhou L, Godlewski G, Harvey-White J, Jeong WI et al. Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice. J Clin Invest 2008; 118: 3160-3169.
-
(2008)
J Clin Invest
, vol.118
, pp. 3160-3169
-
-
Osei-Hyiaman, D.1
Liu, J.2
Zhou, L.3
Godlewski, G.4
Harvey-White, J.5
Jeong, W.I.6
-
135
-
-
58149128824
-
Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats
-
Nogueiras R, Veyrat-Durebex C, Suchanek PM, Klein M, Tschop J, Caldwell C et al. Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats. Diabetes 2008; 57: 2977-2991.
-
(2008)
Diabetes
, vol.57
, pp. 2977-2991
-
-
Nogueiras, R.1
Veyrat-Durebex, C.2
Suchanek, P.M.3
Klein, M.4
Tschop, J.5
Caldwell, C.6
-
136
-
-
37349059404
-
Cannabinoids inhibit insulin secretion and cytosolic Ca2 + oscillation in islet beta-cells via CB1 receptors
-
Nakata M, Yada T. Cannabinoids inhibit insulin secretion and cytosolic Ca2 + oscillation in islet beta-cells via CB1 receptors. Regul Pept 2008; 145: 49-53.
-
(2008)
Regul Pept
, vol.145
, pp. 49-53
-
-
Nakata, M.1
Yada, T.2
-
137
-
-
55749095211
-
Over-active endocannabinoid signaling impairs apolipoprotein E-mediated clearance oftriglyceride-rich lipoproteins
-
Ruby MA, Nomura DK, Hudak CS, Mangravite LM, Chiu S, Casida JE et al. Over-active endocannabinoid signaling impairs apolipoprotein E-mediated clearance oftriglyceride-rich lipoproteins. Proc Natl Acad Sci USA 2008; 105: 14561-14566.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14561-14566
-
-
Ruby, M.A.1
Nomura, D.K.2
Hudak, C.S.3
Mangravite, L.M.4
Chiu, S.5
Casida, J.E.6
-
138
-
-
79954991696
-
Efficacy and safety of topiramate on weight loss: A meta-analysis of randomized controlled trials
-
Kramer CK, Leitao CB, Pinto LC, Canani LH, Azevedo MJ, Gross JL. Efficacy and safety of topiramate on weight loss: a meta-analysis of randomized controlled trials. Obes Rev 2011; 12: e338-e347.
-
(2011)
Obes Rev
, vol.12
-
-
Kramer, C.K.1
Leitao, C.B.2
Pinto, L.C.3
Canani, L.H.4
Azevedo, M.J.5
Gross, J.L.6
-
139
-
-
77951975951
-
Topiramate for prevention of olanzapine associated weight gain and metabolic dysfunction in schizophrenia: A double-blind, placebo-controlled trial
-
Narula PK, Rehan HS, Unni KE, Gupta N. Topiramate for prevention of olanzapine associated weight gain and metabolic dysfunction in schizophrenia: a double-blind, placebo-controlled trial. Schizophr Res 2010; 118: 218-223.
-
(2010)
Schizophr Res
, vol.118
, pp. 218-223
-
-
Narula, P.K.1
Rehan, H.S.2
Unni, K.E.3
Gupta, N.4
-
140
-
-
34447123109
-
Topiramate monotherapy in newly diagnosed epilepsy in children and adolescents
-
Glauser TA, Dlugos DJ, Dodson WE, Grinspan A, Wang S, Wu SC. Topiramate monotherapy in newly diagnosed epilepsy in children and adolescents. J Child Neurol 2007; 22: 693-699.
-
(2007)
J Child Neurol
, vol.22
, pp. 693-699
-
-
Glauser, T.A.1
Dlugos, D.J.2
Dodson, W.E.3
Grinspan, A.4
Wang, S.5
Wu, S.C.6
-
141
-
-
44249094151
-
Topiramate in the prevention of pediatric migraine: Literature review
-
Ferraro D, Di Trapani G. Topiramate in the prevention of pediatric migraine: literature review. J Headache Pain 2008; 9: 147-150.
-
(2008)
J Headache Pain
, vol.9
, pp. 147-150
-
-
Ferraro, D.1
Di Trapani, G.2
-
143
-
-
0036750910
-
Topiramate plus risperidone for controlling weight gain and symptoms in preschool mania
-
Pavuluri MN, Janicak PG, Carbray J. Topiramate plus risperidone for controlling weight gain and symptoms in preschool mania. J Child Adolesc Psychopharmacol 2002; 12: 271-273.
-
(2002)
J Child Adolesc Psychopharmacol
, vol.12
, pp. 271-273
-
-
Pavuluri, M.N.1
Janicak, P.G.2
Carbray, J.3
-
144
-
-
14644423907
-
Clinical experience with Topiramate to counteract neuroleptic induced weight gain in 10 individuals with autistic spectrum disorders
-
Canitano R. Clinical experience with Topiramate to counteract neuroleptic induced weight gain in 10 individuals with autistic spectrum disorders. Brain Dev 2005; 27: 228-232.
-
(2005)
Brain Dev
, vol.27
, pp. 228-232
-
-
Canitano, R.1
-
147
-
-
77953227564
-
A pregnant pause toconsider teratogenicity of topiramate
-
Fountain NB.A pregnant pause toconsider teratogenicity of topiramate. Epilepsy Curr 2009; 9: 36-38.
-
(2009)
Epilepsy Curr
, vol.9
, pp. 36-38
-
-
Fountain, N.B.1
-
149
-
-
77953707385
-
Brainstem mechanisms of amylin-induced anorexia
-
Potes CS, Lutz TA. Brainstem mechanisms of amylin-induced anorexia. Physiol Behav 2010; 100: 511-518.
-
(2010)
Physiol Behav
, vol.100
, pp. 511-518
-
-
Potes, C.S.1
Lutz, T.A.2
-
150
-
-
8744264162
-
Amylin receptors: Molecular composition and pharmacology
-
Hay DL, Christopoulos G, Christopoulos A, Sexton PM. Amylin receptors: molecular composition and pharmacology. Biochem Soc Trans 2004; 32(Partt 5): 865-867.
-
(2004)
Biochem Soc Trans
, vol.32
, Issue.PARTT 5
, pp. 865-867
-
-
Hay, D.L.1
Christopoulos, G.2
Christopoulos, A.3
Sexton, P.M.4
-
151
-
-
78650636365
-
The effect of pramlintide acetate on glycemic control and weight in patients with type 2 diabetes mellitus and in obese patients without diabetes: A systematic review and meta-analysis
-
Singh-Franco D, Perez A, Harrington C. The effect of pramlintide acetate on glycemic control and weight in patients with type 2 diabetes mellitus and in obese patients without diabetes: a systematic review and meta-analysis. Diabetes Obes Metab 2011; 13: 169-180.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 169-180
-
-
Singh-Franco, D.1
Perez, A.2
Harrington, C.3
-
152
-
-
0346368339
-
Effect of pramlintide on A1C and body weight in insulin-treated African Americans and Hispanics with type 2 diabetes: A pooled post hoc analysis
-
Maggs D, Shen L, Strobel S, Brown D, Kolterman O, Weyer C. Effect of pramlintide on A1C and body weight in insulin-treated African Americans and Hispanics with type 2 diabetes: a pooled post hoc analysis. Metabolism 2003; 52: 1638-1642.
-
(2003)
Metabolism
, vol.52
, pp. 1638-1642
-
-
Maggs, D.1
Shen, L.2
Strobel, S.3
Brown, D.4
Kolterman, O.5
Weyer, C.6
-
153
-
-
34547739135
-
Progressive reduction in body weight after treatment with the amylin analog pramlintide in obese subjects: A phase 2, randomized, placebo-controlled, dose-escalation study
-
Aronne L, Fujioka K, Aroda V, Chen K, Halseth A, Kesty NC et al. Progressive reduction in body weight after treatment with the amylin analog pramlintide in obese subjects: a phase 2, randomized, placebo-controlled, dose-escalation study. J Clin Endocrinol Metab 2007; 92: 2977-2983.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 2977-2983
-
-
Aronne, L.1
Fujioka, K.2
Aroda, V.3
Chen, K.4
Halseth, A.5
Kesty, N.C.6
-
154
-
-
56149124659
-
Sustained weight loss following 12-month pramlintide treatment as an adjunct to lifestyle inter-vention in obesity
-
Smith SR, Aronne LJ, Burns CM, Kesty NC, Halseth AE, Weyer C. Sustained weight loss following 12-month pramlintide treatment as an adjunct to lifestyle inter-vention in obesity. Diabetes Care 2008; 31: 1816-1823.
-
(2008)
Diabetes Care
, vol.31
, pp. 1816-1823
-
-
Smith, S.R.1
Aronne, L.J.2
Burns, C.M.3
Kesty, N.C.4
Halseth, A.E.5
Weyer, C.6
-
155
-
-
69249228579
-
Pramlintide lowered glucose excursions and was well-tolerated in adolescents with type 1 diabetes: Results from a randomized, single-blind, placebo-controlled, crossover study
-
Chase HP, Lutz K, Pencek R, Zhang B, Porter L. Pramlintide lowered glucose excursions and was well-tolerated in adolescents with type 1 diabetes: results from a randomized, single-blind, placebo-controlled, crossover study. J Pediatr 2009; 155: 369-373.
-
(2009)
J Pediatr
, vol.155
, pp. 369-373
-
-
Chase, H.P.1
Lutz, K.2
Pencek, R.3
Zhang, B.4
Porter, L.5
-
156
-
-
70350475660
-
A pilot trial of pramlintide home usage in adolescents with type 1 diabetes
-
Kishiyama CM, Burdick PL, Cobry EC, Gage VL, Messer LH, Mc Fann K et al. A pilot trial of pramlintide home usage in adolescents with type 1 diabetes. Pediatrics 2009; 124: 1344-1347.
-
(2009)
Pediatrics
, vol.124
, pp. 1344-1347
-
-
Kishiyama, C.M.1
Burdick, P.L.2
Cobry, E.C.3
Gage, V.L.4
Messer, L.H.5
Mc Fann, K.6
-
157
-
-
0035216623
-
Ghrelin enhances appetite and increases food intake in humans
-
Wren AM, Seal LJ, Cohen MA, Brynes AE, Frost GS, Murphy KG et al. Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab 2001; 86: 5992.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 5992
-
-
Wren, A.M.1
Seal, L.J.2
Cohen, M.A.3
Brynes, A.E.4
Frost, G.S.5
Murphy, K.G.6
-
158
-
-
0036061558
-
Elevated plasma ghrelin levels in Prader Willi syndrome
-
Cummings DE, Clement K, Purnell JQ,Vaisse C, Foster KE, Frayo RS et al. Elevated plasma ghrelin levels in Prader Willi syndrome. Nat Med 2002; 8: 643-644.
-
(2002)
Nat Med
, vol.8
, pp. 643-644
-
-
Cummings, D.E.1
Clement, K.2
Purnell Jqvaisse, C.3
Foster, K.E.4
Frayo, R.S.5
-
159
-
-
54049083786
-
Long-acting octreotide treatment causes a sustained decrease in ghrelin con-centrations but does not affect weight, behaviour and appetite in subjects with Prader-Willi syndrome
-
De Waele K, Ishkanian SL, Bogarin R, Miranda CA, Ghatei MA, Bloom SR et al. Long-acting octreotide treatment causes a sustained decrease in ghrelin con-centrations but does not affect weight, behaviour and appetite in subjects with Prader-Willi syndrome. Eur J Endocrinol 2008; 159: 381-388.
-
(2008)
Eur J Endocrinol
, vol.159
, pp. 381-388
-
-
De Waele, K.1
Ishkanian, S.L.2
Bogarin, R.3
Miranda, C.A.4
Ghatei, M.A.5
Bloom, S.R.6
-
160
-
-
70350619609
-
Effects of liraglutide in the treatment of obesity: A randomised, double-blind, placebo-controlled study
-
Astrup A, Rossner S, Van Gaal L, Rissanen A, Niskanen L, Al Hakim M etal. Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study. Lancet 2009; 374: 1606-1616.
-
(2009)
Lancet
, vol.374
, pp. 1606-1616
-
-
Astrup, A.1
Rossner, S.2
Van Gaal, L.3
Rissanen, A.4
Niskanen, L.5
Al Hakim, M.6
-
161
-
-
67650066860
-
Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met + TZD)
-
Zinman B, Gerich J, Buse JB, Lewin A, Schwartz S, Raskin P et al. Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met + TZD). Diabetes Care 2009; 32: 1224-1230.
-
(2009)
Diabetes Care
, vol.32
, pp. 1224-1230
-
-
Zinman, B.1
Gerich, J.2
Buse, J.B.3
Lewin, A.4
Schwartz, S.5
Raskin, P.6
-
162
-
-
69949117621
-
Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met + SU): A randomised controlled trial
-
Russell-Jones D, Vaag A, Schmitz O, Sethi BK, Lalic N, Antic S et al. Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met + SU): a randomised controlled trial. Diabetologia 2009; 52: 2046-2055.
-
(2009)
Diabetologia
, vol.52
, pp. 2046-2055
-
-
Russell-Jones, D.1
Vaag, A.2
Schmitz, O.3
Sethi, B.K.4
Lalic, N.5
Antic, S.6
-
163
-
-
67649523294
-
Treatment with the human once-weekly glucagon-like peptide-1 analog taspoglutide in combina-tion with metformin improves glycemic control and lowers body weight in patients with type 2 diabetes inadequately controlled with metformin alone: A double-blind placebo-controlled study
-
Nauck MA, Ratner RE, Kapitza C, Berria R, Boldrin M, Balena R. Treatment with the human once-weekly glucagon-like peptide-1 analog taspoglutide in combina-tion with metformin improves glycemic control and lowers body weight in patients with type 2 diabetes inadequately controlled with metformin alone: a double-blind placebo-controlled study. Diabetes Care 2009; 32: 1237-1243.
-
(2009)
Diabetes Care
, vol.32
, pp. 1237-1243
-
-
Nauck, M.A.1
Ratner, R.E.2
Kapitza, C.3
Berria, R.4
Boldrin, M.5
Balena, R.6
-
164
-
-
62449169287
-
Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: The LEAD (liraglutide effect and action in diabetes)-2 study
-
Nauck M, Frid A, Hermansen K, Shah NS, Tankova T, Mitha IH et al. Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study. Diabetes Care 2009; 32: 84-90.
-
(2009)
Diabetes Care
, vol.32
, pp. 84-90
-
-
Nauck, M.1
Frid, A.2
Hermansen, K.3
Shah, N.S.4
Tankova, T.5
Mitha, I.H.6
-
165
-
-
59449101432
-
Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): A randomised, 52-week, phase III, double-blind, parallel-treat-ment trial
-
Garber A, Henry R, Ratner R, Garcia-Hernandez PA, Rodriguez-Pattzi H, Olvera-Alvarez I et al. Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treat-ment trial. Lancet 2009; 373: 473-481.
-
(2009)
Lancet
, vol.373
, pp. 473-481
-
-
Garber, A.1
Henry, R.2
Ratner, R.3
Garcia-Hernandez, P.A.4
Rodriguez-Pattzi, H.5
Olvera-Alvarez, I.6
-
166
-
-
79958268386
-
Exenatide once weekly treatment maintained improvements in glycemic control and weight loss over 2 years
-
Taylor K, Gurney K, Han J, Pencek R, Walsh B, Trautmann M. Exenatide once weekly treatment maintained improvements in glycemic control and weight loss over 2 years. BMC Endocr Disord 2011; 11: 9.
-
(2011)
BMC Endocr Disord
, vol.11
, pp. 9
-
-
Taylor, K.1
Gurney, K.2
Han, J.3
Pencek, R.4
Walsh, B.5
Trautmann, M.6
-
167
-
-
77956090389
-
Effects of exenatide and lifestyle modification on body weight and glucose tolerance in obese subjects with and without pre-diabetes
-
Rosenstock J, Klaff LJ, Schwartz S, Northrup J, Holcombe JH, Wilhelm K et al. Effects of exenatide and lifestyle modification on body weight and glucose tolerance in obese subjects with and without pre-diabetes. Diabetes Care 2010; 33: 1173-1175.
-
(2010)
Diabetes Care
, vol.33
, pp. 1173-1175
-
-
Rosenstock, J.1
Klaff, L.J.2
Schwartz, S.3
Northrup, J.4
Holcombe, J.H.5
Wilhelm, K.6
-
168
-
-
84856242456
-
Exenatide as a weight-loss therapy in extreme pediatric obesity: A randomized, controlled pilot study
-
Kelly AS, Metzig AM, Rudser KD, Fitch AK, Fox CK, Nathan BM et al. Exenatide as a weight-loss therapy in extreme pediatric obesity: a randomized, controlled pilot study. Obesity (Silver Spring) 2012; 20: 364-370.
-
(2012)
Obesity (Silver Spring)
, vol.20
, pp. 364-370
-
-
Kelly, A.S.1
Metzig, A.M.2
Rudser, K.D.3
Fitch, A.K.4
Fox, C.K.5
Nathan, B.M.6
-
169
-
-
84872112680
-
-
US Food and Drug Administration Orlistat Update Accessed: 30 March 2012
-
Mathis LL. US Food and Drug Administration. Pediatric Advisory Committee Meeting March 22, 2010. Orlistat Update. http://www.fda.gov/downloads/Advi-sory Committees/Committees Meeting Materials/Pediatric Advisory Committee/ UCM205380.pdf. Accessed: 30 March 2012.
-
(2010)
Pediatric Advisory Committee Meeting March
, vol.22
-
-
Mathis, L.L.1
-
170
-
-
0036633087
-
Three-month tolerability of orlistat in adolescents with obesity-related comorbid conditions
-
Mc Duffie JR, Calis KA, Uwaifo GI, Sebring NG, Fallon EM, Hubbard VS et al. Three-month tolerability of orlistat in adolescents with obesity-related comorbid conditions. Obes Res 2002; 10: 642-650.
-
(2002)
Obes Res
, vol.10
, pp. 642-650
-
-
Mc Duffie, J.R.1
Calis, K.A.2
Uwaifo, G.I.3
Sebring, N.G.4
Fallon, E.M.5
Hubbard, V.S.6
-
171
-
-
0141988881
-
The effect ofshort-term (21-day) orlistat treatment on the physiologic balance of six selected macrominerals and microminerals in obese adolescents
-
Zhi J, Moore R, Kanitra L. The effect ofshort-term (21-day) orlistat treatment on the physiologic balance of six selected macrominerals and microminerals in obese adolescents. J Am Coll Nutr 2003; 22: 357-362.
-
(2003)
J Am Coll Nutr
, vol.22
, pp. 357-362
-
-
Zhi, J.1
Moore, R.2
Kanitra, L.3
-
172
-
-
0042375748
-
Orlistat treatment in obese prepubertal children: A pilot study
-
Norgren S, Danielsson P, Jurold R, Lotborn M, Marcus C. Orlistat treatment in obese prepubertal children: a pilot study. Acta Paediatr 2003; 92: 666-670.
-
(2003)
Acta Paediatr
, vol.92
, pp. 666-670
-
-
Norgren, S.1
Danielsson, P.2
Jurold, R.3
Lotborn, M.4
Marcus, C.5
-
173
-
-
11244356604
-
Addition of orlistat to conventional treatment in adolescents with severe obesity
-
Ozkan B, Bereket A, Turan S, Keskin S. Addition of orlistat to conventional treatment in adolescents with severe obesity. Eur J Pediatr 2004; 163: 738-741.
-
(2004)
Eur J Pediatr
, vol.163
, pp. 738-741
-
-
Ozkan, B.1
Bereket, A.2
Turan, S.3
Keskin, S.4
-
174
-
-
3142701722
-
Efficacy of orlistat as an adjunct to behavioral treatment in overweight African American and Caucasian adolescents with obesity-related co-morbid conditions
-
Mc Duffie JR, Calis KA, Uwaifo GI, Sebring NG, Fallon EM, Frazer TE et al. Efficacy of orlistat as an adjunct to behavioral treatment in overweight African American and Caucasian adolescents with obesity-related co-morbid conditions. J Pediatr Endocrinol Metab 2004; 17: 307-319.
-
(2004)
J Pediatr Endocrinol Metab
, vol.17
, pp. 307-319
-
-
Mc Duffie, J.R.1
Calis, K.A.2
Uwaifo, G.I.3
Sebring, N.G.4
Fallon, E.M.5
Frazer, T.E.6
-
175
-
-
20444446770
-
Effect of orlistat on weight and body composition in obese adolescents: A randomized controlled trial
-
Chanoine JP, Hampl S, Jensen C, Boldrin M, Hauptman J. Effect of orlistat on weight and body composition in obese adolescents: a randomized controlled trial. Jama 2005; 293: 2873-2883.
-
(2005)
JAMA
, vol.293
, pp. 2873-2883
-
-
Chanoine, J.P.1
Hampl, S.2
Jensen, C.3
Boldrin, M.4
Hauptman, J.5
-
176
-
-
33646842569
-
Randomized, double-blind, placebo-controlled trial of orlistat for weight loss in adolescents
-
Maahs D, de Serna DG, Kolotkin RL, Ralston S, Sandate J, Qualls C et al. Randomized, double-blind, placebo-controlled trial of orlistat for weight loss in adolescents. Endocr Pract 2006; 12: 18-28.
-
(2006)
Endocr Pract
, vol.12
, pp. 18-28
-
-
Maahs, D.1
De Serna, D.G.2
Kolotkin, R.L.3
Ralston, S.4
Sandate, J.5
Qualls, C.6
-
177
-
-
79957468976
-
Early weight loss and outcome at one year in obese adolescents treated with orlistat or placebo
-
Chanoine JP, Richard M. Early weight loss and outcome at one year in obese adolescents treated with orlistat or placebo. Int J Pediatr Obes 2011; 6: 95-101.
-
(2011)
Int J Pediatr Obes
, vol.6
, pp. 95-101
-
-
Chanoine, J.P.1
Richard, M.2
-
178
-
-
84872118968
-
A randomized placebo-controlled trial of the effects of orlistat on body weight and body composition in african american and caucasian adolescents with obesity-related comorbid conditions
-
Yanovski JA, Mc Duffie JR, Salaita CS, Tanofsky-Kraff M, Sebring NG, Young-Hyman D et al. A randomized, placebo-controlled trial of the effects of orlistat on body weight and body composition in African American and Caucasian adolescents with obesity-related comorbid conditions. Obesity2008; 16(Suppl. 1): S63.
-
(2008)
Obesity
, vol.16
, Issue.SUPPL. 1
-
-
Yanovski, J.A.1
Mc Duffie, J.R.2
Salaita, C.S.3
Tanofsky-Kraff, M.4
Sebring, N.G.5
Young-Hyman, D.6
-
180
-
-
70449534919
-
Pattern of orlistat exposures in children aged 5 years or less
-
Forrester MB. Pattern of orlistat exposures in children aged 5 years or less. J Emerg Med 2009; 37: 396-399.
-
(2009)
J Emerg Med
, vol.37
, pp. 396-399
-
-
Forrester, M.B.1
-
181
-
-
77954424747
-
An Orlistat 'overdose' in a child
-
O'Connor MB. An orlistat 'overdose' in a child. Ir JMed Sci 2010; 179: 315.
-
(2010)
Ir JMed Sci
, vol.179
, pp. 315
-
-
O'Connor, M.B.1
-
182
-
-
1042303480
-
XENical in the prevention of diabetes in obese subjects (XENDOS) study: A randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients
-
Torgerson JS, Hauptman J, Boldrin MN, Sjostrom L. XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care 2004; 27: 155-161.
-
(2004)
Diabetes Care
, vol.27
, pp. 155-161
-
-
Torgerson, J.S.1
Hauptman, J.2
Boldrin, M.N.3
Sjostrom, L.4
-
183
-
-
0035990352
-
Effects of orlistat on fat-soluble vitamins in obese adolescents
-
Mc Duffie JR, Calis KA, Booth SL, Uwaifo GI, Yanovski JA. Effects of orlistat on fat-soluble vitamins in obese adolescents. Pharmacotherapy 2002; 22: 814-822.
-
(2002)
Pharmacotherapy
, vol.22
, pp. 814-822
-
-
Mc Duffie, J.R.1
Calis, K.A.2
Booth, S.L.3
Uwaifo, G.I.4
Yanovski, J.A.5
-
184
-
-
37549010380
-
-
FDA Accessed: 9 July 2012
-
FDA. Approves Orlistat for Over-the-Counter Use. http://www.fda.gov/News Events/Newsroom/Press Announcements/2007/ucm108839.htm. Accessed: 9 July 2012.
-
Approves Orlistat for Over-the-Counter Use
-
-
-
185
-
-
33847261129
-
Cetilistat (ATL-962), a novel lipase inhibitor: A 12-week randomized, placebo-controlled study of weight reduction in obese patients
-
Kopelman P, Bryson A, Hickling R, Rissanen A, Rossner S, Toubro S et al. Cetilistat (ATL-962), a novel lipase inhibitor: a 12-week randomized, placebo-controlled study of weight reduction in obese patients. Int J Obes (Lond) 2007; 31: 494-499.
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 494-499
-
-
Kopelman, P.1
Bryson, A.2
Hickling, R.3
Rissanen, A.4
Rossner, S.5
Toubro, S.6
-
186
-
-
73949084345
-
Weight loss, Hb A 1c reduction, and tolerability of cetilistat in a randomized, placebo-controlled phase 2 trial in obese diabetics: Comparison with orlistat (xenical)
-
Kopelman P, Groot Gde H, Groot G, Rissanen A, Rossner S, Toubro S et al. Weight loss, Hb A 1c reduction, and tolerability of cetilistat in a randomized, placebo-controlled phase 2 trial in obese diabetics: comparison with orlistat (xenical). Obesity2010; 18: 108-115.
-
(2010)
Obesity
, vol.18
, pp. 108-115
-
-
Kopelman, P.1
Groot Gde, H.2
Groot, G.3
Rissanen, A.4
Rossner, S.5
Toubro, S.6
-
187
-
-
73949084345
-
Weight loss, Hb A1c reduction, and tolerability of cetilistat in a randomized, placebo-controlled phase 2 trial in obese diabetics: Comparison with orlistat (Xenical)
-
Kopelman P, Groot Gde H, Rissanen A, Rossner S, Toubro S, Palmer R et al. Weight loss, Hb A1c reduction, and tolerability of cetilistat in a randomized, placebo-controlled phase 2 trial in obese diabetics: comparison with orlistat (Xenical). Obesity (Silver Spring) 2010; 18: 108-115.
-
(2010)
Obesity (Silver Spring)
, vol.18
, pp. 108-115
-
-
Kopelman, P.1
Groot Gde, H.2
Rissanen, A.3
Rossner, S.4
Toubro, S.5
Palmer, R.6
-
188
-
-
0030066421
-
Pharmacokinetic-pharmacodynamic relationships of Acarbose
-
Salvatore T, Giugliano D. Pharmacokinetic-pharmacodynamic relationships of Acarbose. Clin Pharmacokinet 1996; 30: 94-106.
-
(1996)
Clin Pharmacokinet
, vol.30
, pp. 94-106
-
-
Salvatore, T.1
Giugliano, D.2
-
189
-
-
83455220076
-
Effects of acarbose versus glibenclamide on glycemic excursion and oxidative stress in type 2 diabetic patients inadequately controlled by metformin: A 24-week, randomized, open-label, parallel-group comparison
-
Wang JS, Lin SD, Lee WJ, Su SL, Lee IT, Tu ST et al. Effects of acarbose versus glibenclamide on glycemic excursion and oxidative stress in type 2 diabetic patients inadequately controlled by metformin: a 24-week, randomized, open-label, parallel-group comparison. Clin Ther 2011; 33: 1932-1942.
-
(2011)
Clin Ther
, vol.33
, pp. 1932-1942
-
-
Wang, J.S.1
Lin, S.D.2
Lee, W.J.3
Su, S.L.4
Lee, I.T.5
Tu, S.T.6
-
190
-
-
0030870853
-
Small weight loss on long-term acarbose therapy with no change in dietary pattern or nutrient intake of individuals with non-insulin-dependent diabetes
-
Wolever TM, Chiasson JL, Josse RG, Hunt JA, Palmason C, Rodger NW et al. Small weight loss on long-term acarbose therapy with no change in dietary pattern or nutrient intake of individuals with non-insulin-dependent diabetes. Int J Obes Relat Metab Disord 1997; 21: 756-763.
-
(1997)
Int J Obes Relat Metab Disord
, vol.21
, pp. 756-763
-
-
Wolever, T.M.1
Chiasson, J.L.2
Josse, R.G.3
Hunt, J.A.4
Palmason, C.5
Rodger, N.W.6
-
191
-
-
52949100161
-
Clinical, endocrine, and metabolic effects of acarbose, a alpha-glucosidase inhibitor, in overweight and nonoverweight patients with polycystic ovarian syndrome
-
Tugrul S, Kutlu T, Pekin O, Baglam E, Kiyak H, Oral O. Clinical, endocrine, and metabolic effects of acarbose, a alpha-glucosidase inhibitor, in overweight and nonoverweight patients with polycystic ovarian syndrome. Fertil Steril 2008; 90: 1144-1148.
-
(2008)
Fertil Steril
, vol.90
, pp. 1144-1148
-
-
Tugrul, S.1
Kutlu, T.2
Pekin, O.3
Baglam, E.4
Kiyak, H.5
Oral, O.6
-
192
-
-
77953734934
-
Single-dose pharmacokinetics and pharmacodynamics of sergliflozin eta-bonate, a novel inhibitor of glucose reabsorption, in healthy volunteers and patients with type 2 diabetes mellitus
-
Hussey EK, Clark RV, Amin DM, Kipnes MS, O'Connor-Semmes RL, O'Driscoll EC et al. Single-dose pharmacokinetics and pharmacodynamics of sergliflozin eta-bonate, a novel inhibitor of glucose reabsorption, in healthy volunteers and patients with type 2 diabetes mellitus. J Clin Pharmacol 2010; 50: 623-635.
-
(2010)
J Clin Pharmacol
, vol.50
, pp. 623-635
-
-
Hussey, E.K.1
Clark, R.V.2
Amin, D.M.3
Kipnes, M.S.4
O'Connor-Semmes, R.L.5
O'Driscoll, E.C.6
-
193
-
-
77953801665
-
Multiple-dose pharmacokinetics and pharmacodynamics of sergliflozin etabonate, a novel inhibitor ofglucose reabsorption, in healthy overweight and obese subjects: A randomized double-blind study
-
Hussey EK, Dobbins RL, Stoltz RR, Stockman NL, O'Connor-Semmes RL, Kapur A et al. Multiple-dose pharmacokinetics and pharmacodynamics of sergliflozin etabonate, a novel inhibitor ofglucose reabsorption, in healthy overweight and obese subjects: a randomized double-blind study. J Clin Pharmacol 2010; 50: 636-646.
-
(2010)
J Clin Pharmacol
, vol.50
, pp. 636-646
-
-
Hussey, E.K.1
Dobbins, R.L.2
Stoltz, R.R.3
Stockman, N.L.4
O'Connor-Semmes, R.L.5
Kapur, A.6
-
194
-
-
67349180574
-
Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects
-
Komoroski B, Vachharajani N, Boulton D, Kornhauser D, Geraldes M, Li L et al. Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects. Clin Pharmacol Ther 2009; 85: 520-526.
-
(2009)
Clin Pharmacol Ther
, vol.85
, pp. 520-526
-
-
Komoroski, B.1
Vachharajani, N.2
Boulton, D.3
Kornhauser, D.4
Geraldes, M.5
Li, L.6
-
195
-
-
77953181310
-
Dapagliflozin treatment in patients with different stages oftype 2 diabetes mellitus: Effects on glycaemic control and body weight
-
Zhang L, Feng Y, List J, Kasichayanula S, Pfister M. Dapagliflozin treatment in patients with different stages oftype 2 diabetes mellitus: effects on glycaemic control and body weight. Diabetes Obes Metab 2010; 12: 510-516.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 510-516
-
-
Zhang, L.1
Feng, Y.2
List, J.3
Kasichayanula, S.4
Pfister, M.5
-
196
-
-
80052524011
-
Effect of dapagli-flozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: A randomized, 24-week, double-blind, placebo-controlled trial
-
Strojek K, Yoon KH, Hruba V, Elze M, Langkilde AM, Parikh S. Effect of dapagli-flozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomized, 24-week, double-blind, placebo-controlled trial. Diabetes Obes Metab 2011; 13: 928-938.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 928-938
-
-
Strojek, K.1
Yoon, K.H.2
Hruba, V.3
Elze, M.4
Langkilde, A.M.5
Parikh, S.6
-
197
-
-
80155124676
-
Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: A randomized, 52-week, double-blind, active-controlled noninferiority trial
-
Nauck MA, Del Prato S, Meier JJ, Duran-Garcia S, Rohwedder K, Elze M et al. Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: a randomized, 52-week, double-blind, active-controlled noninferiority trial. Diabetes Care 2011; 34: 2015-2022.
-
(2011)
Diabetes Care
, vol.34
, pp. 2015-2022
-
-
Nauck, M.A.1
Del Prato, S.2
Meier, J.J.3
Duran-Garcia, S.4
Rohwedder, K.5
Elze, M.6
-
198
-
-
84858020943
-
Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin
-
Bolinder J, Ljunggren O, Kullberg J, Johansson L, Wilding J, Langkilde AM et al. Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin. J Clin Endocrinol Metab 2012; 97: 1020-1031.
-
(2012)
J Clin Endocrinol Metab
, vol.97
, pp. 1020-1031
-
-
Bolinder, J.1
Ljunggren, O.2
Kullberg, J.3
Johansson, L.4
Wilding, J.5
Langkilde, A.M.6
-
199
-
-
84872109163
-
-
Pharma Times Online. Published on-line 07/20/2011 Accessed: 25 November 2011
-
Grogan K. FDA panel rejects B-MS/AZ's diabetes drug...but only just. Pharma Times Online. Published on-line 07/20/2011 http://www.pharmatimes.com/ Arti-cle/11-07-20/FDA-panel-rejects-B-MS-AZ-s-diabetes-drug-but-only-just.aspx. Accessed: 25 November 2011.
-
FDA Panel Rejects B-MS/AZ's Diabetes Drug..But only Just
-
-
Grogan, K.1
-
200
-
-
0034968529
-
Metformin, the rebirth of a biguanide: Mechanism of action and place in the prevention and treatment of insulin resistance
-
Mehnert H. Metformin, the rebirth of a biguanide: mechanism of action and place in the prevention and treatment of insulin resistance. Exp Clin Endocrinol Diabetes 2001; 109(Suppl 2): S259-S264.
-
(2001)
Exp Clin Endocrinol Diabetes
, vol.109
, Issue.SUPPL. 2
-
-
Mehnert, H.1
-
201
-
-
0041736553
-
Metformin: New understandings, new uses
-
Hundal RS, Inzucchi SE. Metformin: new understandings, new uses. Drugs 2003; 63: 1879-1894.
-
(2003)
Drugs
, vol.63
, pp. 1879-1894
-
-
Hundal, R.S.1
Inzucchi, S.E.2
-
202
-
-
20544470723
-
Addressing theglobal cardiovascular riskofhypertension, dyslipidemia, diabetes mellitus, and the metabolic syndrome in the southeastern United States, part II: Treatment recommendations for management of the global cardiovascular risk of hypertension, dyslipidemia, diabetes mellitus, and the metabolic syndrome
-
Bestermann W, Houston MC, Basile J, Egan B, Ferrario CM, Lackland D et al. Addressing theglobal cardiovascular riskofhypertension, dyslipidemia, diabetes mellitus, and the metabolic syndrome in the southeastern United States, part II: treatment recommendations for management of the global cardiovascular risk of hypertension, dyslipidemia, diabetes mellitus, and the metabolic syndrome. Am J Med Sci 2005; 329: 292-305.
-
(2005)
Am J Med Sci
, vol.329
, pp. 292-305
-
-
Bestermann, W.1
Houston, M.C.2
Basile, J.3
Egan, B.4
Ferrario, C.M.5
Lackland, D.6
-
203
-
-
0037034257
-
Reduction in the incidence oftype 2 diabetes with lifestyle intervention or metformin
-
Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA et al. Reduction in the incidence oftype 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002; 346: 393-403.
-
(2002)
N Engl J Med
, vol.346
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
Hamman, R.F.4
Lachin, J.M.5
Walker, E.A.6
-
204
-
-
78649638455
-
A randomized, triple masked, placebo-controlled clinical trial for controlling childhood obesity
-
Rezvanian H, Hashemipour M, Kelishadi R,Tavakoli N, Poursafa P. A randomized, triple masked, placebo-controlled clinical trial for controlling childhood obesity. World J Pediatr 2010;6:317-322.
-
(2010)
World J Pediatr
, vol.6
, pp. 317-322
-
-
Rezvanian, H.1
Hashemipour, M.2
Kelishadi, R.3
Tavakoli, N.4
Poursafa, P.5
-
205
-
-
0035321014
-
The effects of metformin on body mass index and glu-cose tolerance in obese adolescents with fasting hyperinsulinemia and a family history of type 2 diabetes
-
Freemark M, Bursey D. The effects of metformin on body mass index and glu-cose tolerance in obese adolescents with fasting hyperinsulinemia and a family history of type 2 diabetes. Pediatrics 2001; 107: E55.
-
(2001)
Pediatrics
, vol.107
-
-
Freemark, M.1
Bursey, D.2
-
206
-
-
75849124826
-
Metformin extended release treatment of adolescent obesity: A 48-week randomized, double-blind, placebo-controlled trial with 48-week follow-up
-
Wilson DM, Abrams SH, Aye T, Lee PD, Lenders C, Lustig RH et al. Metformin extended release treatment of adolescent obesity: a 48-week randomized, double-blind, placebo-controlled trial with 48-week follow-up. Arch Pediatr Adolesc Med 2010; 164: 116-123.
-
(2010)
Arch Pediatr Adolesc Med
, vol.164
, pp. 116-123
-
-
Wilson, D.M.1
Abrams, S.H.2
Aye, T.3
Lee, P.D.4
Lenders, C.5
Lustig, R.H.6
-
207
-
-
79551597310
-
Effects of metformin on body weight and body composition in obese insulin-resistant children: A randomized clinical trial
-
Yanovski JA, Krakoff J, Salaita CG, Mc Duffie JR, Kozlosky M, Sebring NG et al. Effects of metformin on body weight and body composition in obese insulin-resistant children: a randomized clinical trial. Diabetes 2011; 60: 477-485.
-
(2011)
Diabetes
, vol.60
, pp. 477-485
-
-
Yanovski, J.A.1
Krakoff, J.2
Salaita, C.G.3
Mc Duffie, J.R.4
Kozlosky, M.5
Sebring, N.G.6
-
208
-
-
33845809235
-
Prevalence of the metabolic syndrome in Zhejiang Chinese obese children and adolescents and the effect of metformin combined with lifestyle intervention
-
Fu JF, Liang L, Zou CC, Hong F, Wang CL, Wang XM et al. Prevalence of the metabolic syndrome in Zhejiang Chinese obese children and adolescents and the effect of metformin combined with lifestyle intervention. Int J Obes (Lond) 2007; 31: 15-22.
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 15-22
-
-
Fu, J.F.1
Liang, L.2
Zou, C.C.3
Hong, F.4
Wang, C.L.5
Wang, X.M.6
-
209
-
-
44949253252
-
Use of metformin in obese adolescents with hyper-insulinemia: A 6-month, randomized, double-blind, placebo-controlled clinical trial
-
Atabek ME, Pirgon O. Use of metformin in obese adolescents with hyper-insulinemia: a 6-month, randomized, double-blind, placebo-controlled clinical trial. J Pediatr Endocrinol Metab 2008; 21: 339-348.
-
(2008)
J Pediatr Endocrinol Metab
, vol.21
, pp. 339-348
-
-
Atabek, M.E.1
Pirgon, O.2
-
210
-
-
70349578941
-
Metformin in combination with structured lifestyle intervention improved body mass index in obese adolescents, but did not improve insulin resistance
-
Clarson CL, Mahmud FH, Baker JE, Clark HE, Mc Kay WM, Schauteet VD et al. Metformin in combination with structured lifestyle intervention improved body mass index in obese adolescents, but did not improve insulin resistance. Endocrine 2009; 36: 141-146.
-
(2009)
Endocrine
, vol.36
, pp. 141-146
-
-
Clarson, C.L.1
Mahmud, F.H.2
Baker, J.E.3
Clark, H.E.4
Mc Kay, W.M.5
Schauteet, V.D.6
-
211
-
-
77957117682
-
Met-formin and placebo therapy both improve weight management and fasting insulin in obese insulin-resistant adolescents: A prospective, placebo-controlled, randomized study
-
Wiegand S, l'Allemand D, Hubel H, Krude H, Burmann M, Martus P et al. Met-formin and placebo therapy both improve weight management and fasting insulin in obese insulin-resistant adolescents: a prospective, placebo-controlled, randomized study. Eur J Endocrinol 2010; 163: 585-592.
-
(2010)
Eur J Endocrinol
, vol.163
, pp. 585-592
-
-
Wiegand, S.1
L'Allemand, D.2
Hubel, H.3
Krude, H.4
Burmann, M.5
Martus, P.6
-
212
-
-
57349135982
-
Impact of metformin, oral contraceptives, and lifestyle modification on polycystic ovary syndrome in obese adolescent women: Do we need a new drug?
-
Legro RS. Impact of metformin, oral contraceptives, and lifestyle modification on polycystic ovary syndrome in obese adolescent women: do we need a new drug? J Clin Endocrinol Metab 2008; 93: 4218-4220.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4218-4220
-
-
Legro, R.S.1
-
213
-
-
31644449390
-
Effects of two forms of combined oral contraceptives on carbohydrate metabolism in adolescents with polycystic ovary syndrome
-
Mastorakos G, Koliopoulos C, Deligeoroglou E, Diamanti-Kandarakis E, Creatsas G. Effects of two forms of combined oral contraceptives on carbohydrate metabolism in adolescents with polycystic ovary syndrome. Fertil Steril 2006; 85: 420-427.
-
(2006)
Fertil Steril
, vol.85
, pp. 420-427
-
-
Mastorakos, G.1
Koliopoulos, C.2
Deligeoroglou, E.3
Diamanti-Kandarakis, E.4
Creatsas, G.5
-
214
-
-
57349113274
-
The impact of metformin, oral contraceptives, and lifestyle modification on polycystic ovary syndrome in obese adolescent women in two randomized, placebo-controlled clinical trials
-
Hoeger K, Davidson K, Kochman L, Cherry T, Kopin L, Guzick DS. The impact of metformin, oral contraceptives, and lifestyle modification on polycystic ovary syndrome in obese adolescent women in two randomized, placebo-controlled clinical trials. J Clin Endocrinol Metab 2008; 93: 4299-4306.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4299-4306
-
-
Hoeger, K.1
Davidson, K.2
Kochman, L.3
Cherry, T.4
Kopin, L.5
Guzick, D.S.6
-
215
-
-
11144354560
-
Ethinylestradiol-drospirenone, flutamide-metformin, or both for adolescents and women with hyperinsulinemic hyperandrogenism: Opposite effects on adipocytokines and body adiposity
-
Ibanez L, de Zegher F. Ethinylestradiol-drospirenone, flutamide-metformin, or both for adolescents and women with hyperinsulinemic hyperandrogenism: opposite effects on adipocytokines and body adiposity. J Clin Endocrinol Metab 2004; 89: 1592-1597.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1592-1597
-
-
Ibanez, L.1
De Zegher, F.2
-
216
-
-
33644868321
-
Randomized placebo-controlled trial of metformin for adolescents with polycystic ovary syndrome
-
Bridger T, Mac Donald S, Baltzer F, Rodd C. Randomized placebo-controlled trial of metformin for adolescents with polycystic ovary syndrome. Arch Pediatr Adolesc Med 2006; 160: 241-246.
-
(2006)
Arch Pediatr Adolesc Med
, vol.160
, pp. 241-246
-
-
Bridger, T.1
Mac Donald, S.2
Baltzer, F.3
Rodd, C.4
-
217
-
-
24944480071
-
Rando-mized controlled trial evaluating response to metformin versus standard therapy in the treatment of adolescents with polycystic ovary syndrome
-
Allen HF, Mazzoni C, Heptulla RA, Murray MA, Miller N, Koenigs L et al. Rando-mized controlled trial evaluating response to metformin versus standard therapy in the treatment of adolescents with polycystic ovary syndrome. J Pediatr Endocrinol Metab 2005; 18: 761-768.
-
(2005)
J Pediatr Endocrinol Metab
, vol.18
, pp. 761-768
-
-
Allen, H.F.1
Mazzoni, C.2
Heptulla, R.A.3
Murray, M.A.4
Miller, N.5
Koenigs, L.6
-
218
-
-
0036283875
-
Metformin therapy in obese adolescents with polycystic ovary syndrome and impaired glucose tolerance: Amelioration of exaggerated adrenal response to adrenocorticotropin with reduction of insulinemia/insulin resistance
-
Arslanian SA, Lewy V, Danadian K, Saad R. Metformin therapy in obese adolescents with polycystic ovary syndrome and impaired glucose tolerance: amelioration of exaggerated adrenal response to adrenocorticotropin with reduction of insulinemia/insulin resistance. J Clin Endocrinol Metab 2002; 87: 1555-1559.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1555-1559
-
-
Arslanian, S.A.1
Lewy, V.2
Danadian, K.3
Saad, R.4
-
219
-
-
33846294762
-
A randomized, double-blind, placebo-controlled trial of metformin treatment of weight gain associated with initiation of atypical antipsychotic therapy in children and adolescents
-
Klein DJ, Cottingham EM, Sorter M, Barton BA, Morrison JA. A randomized, double-blind, placebo-controlled trial of metformin treatment of weight gain associated with initiation of atypical antipsychotic therapy in children and adolescents. Am J Psychiatry 2006; 163: 2072-2079.
-
(2006)
Am J Psychiatry
, vol.163
, pp. 2072-2079
-
-
Klein, D.J.1
Cottingham, E.M.2
Sorter, M.3
Barton, B.A.4
Morrison, J.A.5
-
220
-
-
79251617420
-
Metformin for weight reduction in non-diabetic patients on antipsychotic drugs: A systematic review and meta-analysis
-
Bjorkhem-Bergman L, Asplund AB, Lindh JD. Metformin for weight reduction in non-diabetic patients on antipsychotic drugs: a systematic review and meta-analysis. J Psychopharmacol 2011; 25: 299-305.
-
(2011)
J Psychopharmacol
, vol.25
, pp. 299-305
-
-
Bjorkhem-Bergman, L.1
Asplund, A.B.2
Lindh, J.D.3
-
221
-
-
84859027506
-
Association of bio-chemical B12 deficiency with metformin therapy and vitamin B12 supplements: The national health and nutrition examination survey, 1999-2006
-
Reinstatler L, Qi YP, Williamson RS, Garn JV, Oakley Jr. GP . Association of bio-chemical B12 deficiency with metformin therapy and vitamin B12 supplements: the national health and nutrition examination survey, 1999-2006. Diabetes Care 2012; 35: 327-333.
-
(2012)
Diabetes Care
, vol.35
, pp. 327-333
-
-
Reinstatler, L.1
Qi, Y.P.2
Williamson, R.S.3
Garn, J.V.4
Oakley Jr., G.P.5
-
223
-
-
23044445736
-
Efficacy of octreotide-LAR in dieting women with abdominal obesity and polycystic ovary syndrome
-
Gambineri A, Patton L, De Iasio R, Cantelli B, Cognini GE, Filicori M et al. Efficacy of octreotide-LAR in dieting women with abdominal obesity and polycystic ovary syndrome. J Clin Endocrinol Metab 2005; 90: 3854-3862.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 3854-3862
-
-
Gambineri, A.1
Patton, L.2
De Iasio, R.3
Cantelli, B.4
Cognini, G.E.5
Filicori, M.6
-
224
-
-
0042885664
-
Circulating ghrelin levels are suppressed by meals and octreotide therapy in children with Prader-Willi syndrome
-
Haqq AM, Stadler DD, Rosenfeld RG, Pratt KL, Weigle DS, Frayo RS et al. Circulating ghrelin levels are suppressed by meals and octreotide therapy in children with Prader-Willi syndrome. J Clin Endocrinol Metab 2003; 88: 3573-3576.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 3573-3576
-
-
Haqq, A.M.1
Stadler, D.D.2
Rosenfeld, R.G.3
Pratt, K.L.4
Weigle, D.S.5
Frayo, R.S.6
-
225
-
-
0025915596
-
Growth hormone alters lipolysis and hormone-sensitive lipase activity in 3T3-F442A adipocytes
-
Dietz J, Schwartz J. Growth hormone alters lipolysis and hormone-sensitive lipase activity in 3T3-F442A adipocytes. Metabolism 1991; 40: 800-806.
-
(1991)
Metabolism
, vol.40
, pp. 800-806
-
-
Dietz, J.1
Schwartz, J.2
-
226
-
-
0028895104
-
Resting metabolic rate, body composition and related hormonal parameters in growth hormone-deficient adults before and after growth hormone replace-ment therapy
-
Snel YE, Doerga ME, Brummer RJ, Zelissen PM, Zonderland ML, Koppeschaar HP. Resting metabolic rate, body composition and related hormonal parameters in growth hormone-deficient adults before and after growth hormone replace-ment therapy. Eur J Endocrinol 1995; 133: 445-450.
-
(1995)
Eur J Endocrinol
, vol.133
, pp. 445-450
-
-
Snel, Y.E.1
Doerga, M.E.2
Brummer, R.J.3
Zelissen, P.M.4
Zonderland, M.L.5
Koppeschaar, H.P.6
-
227
-
-
0025808935
-
Changes in body composition and energy expenditure after six weeks' growth hormone treat-ment
-
Gregory JW, Greene SA, Jung RT, Scrimgeour CM, Rennie MJ. Changes in body composition and energy expenditure after six weeks' growth hormone treat-ment. Arch Dis Child 1991; 66: 598-602.
-
(1991)
Arch Dis Child
, vol.66
, pp. 598-602
-
-
Gregory, J.W.1
Greene, S.A.2
Jung, R.T.3
Scrimgeour, C.M.4
Rennie, M.J.5
-
228
-
-
0038305741
-
Short-term effects of growth hormone on body composition as a predictor of growth
-
Hoos MB, Westerterp KR, Gerver WJ. Short-term effects of growth hormone on body composition as a predictor of growth. J Clin Endocrinol Metab 2003; 88: 2569-2572.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 2569-2572
-
-
Hoos, M.B.1
Westerterp, K.R.2
Gerver, W.J.3
-
229
-
-
0344826523
-
Effects of growth hor-mone (GH) on ghrelin, leptin, and adiponectin in GH-deficient patients
-
Eden Engstrom B, Burman P, Holdstock C, Karlsson FA. Effects of growth hor-mone (GH) on ghrelin, leptin, and adiponectin in GH-deficient patients. J Clin Endocrinol Metab 2003; 88: 5193-5198.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 5193-5198
-
-
Eden Engstrom, B.1
Burman, P.2
Holdstock, C.3
Karlsson, F.A.4
-
230
-
-
0037656509
-
Growth hormone treatment improves body composition in adults with Prader-Willi syndrome
-
Hoybye C, Hilding A, Jacobsson H, Thoren M. Growth hormone treatment improves body composition in adults with Prader-Willi syndrome. Clin Endocrinol (Oxf) 2003; 58: 653-661.
-
(2003)
Clin Endocrinol (Oxf)
, vol.58
, pp. 653-661
-
-
Hoybye, C.1
Hilding, A.2
Jacobsson, H.3
Thoren, M.4
-
232
-
-
0033966287
-
Leptin concentrations in Prader-Willi syndrome before and after growth hormone replacement
-
Myers SE, Davis A, Whitman BY, Santiago JV, Landt M. Leptin concentrations in Prader-Willi syndrome before and after growth hormone replacement. Clin Endocrinol (Oxf) 2000; 52: 101-105.
-
(2000)
Clin Endocrinol (Oxf)
, vol.52
, pp. 101-105
-
-
Myers, S.E.1
Davis, A.2
Whitman, B.Y.3
Santiago, J.V.4
Landt, M.5
-
233
-
-
0043231590
-
Effects of growth hormone administration in human obesity
-
Shadid S, Jensen MD. Effects of growth hormone administration in human obesity. Obes Res 2003; 11: 170-175.
-
(2003)
Obes Res
, vol.11
, pp. 170-175
-
-
Shadid, S.1
Jensen, M.D.2
-
234
-
-
75149150720
-
Long-term safety of recombinant human growth hormone in children
-
Bell J, Parker KL, Swinford RD, Hoffman AR, Maneatis T, Lippe B. Long-term safety of recombinant human growth hormone in children. J Clin Endocrinol Metab 2010; 95: 167-177.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 167-177
-
-
Bell, J.1
Parker, K.L.2
Swinford, R.D.3
Hoffman, A.R.4
Maneatis, T.5
Lippe, B.6
-
235
-
-
34247195576
-
-
[Changes in carbohydrate metabolism and insulin resistance in patients with Prader-Willi Syndrome (PWS) under growth hormone therapy]
-
Lammer C, Weimann E. [Changes in carbohydrate metabolism and insulin resistance in patients with Prader-Willi Syndrome (PWS) under growth hormone therapy]. Wien Med Wochenschr 2007; 157: 82-88.
-
(2007)
Wien Med Wochenschr
, vol.157
, pp. 82-88
-
-
Lammer, C.1
Weimann, E.2
-
236
-
-
79151480433
-
Effects ofgrowth hormone therapy on cardiac dimensions in children and adolescents with Prader-Willi syndrome
-
Hauffa BP, Knaup K, Lehmann N, Neudorf U, Nagel B. Effects ofgrowth hormone therapy on cardiac dimensions in children and adolescents with Prader-Willi syndrome. Horm Res Paediatr 2011; 75: 56-62.
-
(2011)
Horm Res Paediatr
, vol.75
, pp. 56-62
-
-
Hauffa, B.P.1
Knaup, K.2
Lehmann, N.3
Neudorf, U.4
Nagel, B.5
-
237
-
-
32544436250
-
Short-term effects of growth hormone on sleep abnormalities in Prader-Willi syndrome
-
Miller J, Silverstein J, Shuster J, Driscoll DJ, Wagner M. Short-term effects of growth hormone on sleep abnormalities in Prader-Willi syndrome. J Clin Endo-crinol Metab 2006; 91: 413-417.
-
(2006)
J Clin Endo-crinol Metab
, vol.91
, pp. 413-417
-
-
Miller, J.1
Silverstein, J.2
Shuster, J.3
Driscoll, D.J.4
Wagner, M.5
-
238
-
-
33845472885
-
Hokken-Koelega AC Sleep-related breathing disorders in prepubertal children with Prader-Willi syndrome and effects of growth hormone treatment
-
Festen DA, de Weerd AW, van den Bossche RA, Joosten K, Hoeve H, Hokken-Koelega AC Sleep-related breathing disorders in prepubertal children with Prader-Willi syndrome and effects of growth hormone treatment. J Clin Endo-crinol Metab 2006; 91: 4911-4915.
-
(2006)
J Clin Endo-crinol Metab
, vol.91
, pp. 4911-4915
-
-
Festen, D.A.1
De Weerd, A.W.2
Van Den Bossche, R.A.3
Joosten, K.4
Hoeve, H.5
-
239
-
-
84872104221
-
-
Genotropin (somatropin [r DNA origin] for injection) Accessed: 10 Jyly 2012
-
Genotropin (somatropin [r DNA origin] for injection). http://www.fda.gov/Safety/ Med Watch/Safety Information/Safety Alertsfor Human Medical Products/ucm153317. htm. Accessed: 10 Jyly 2012.
-
-
-
-
240
-
-
84872111418
-
-
US Food Drug Administration. Med Watch The FDA Safety Information and Adverse Event Reporting Program. Recombinant Human Growth Hormone (somatropin): Ongoing Safety Review - Possible Increased Risk of Death. Posted 12/22/2010 Accessed: 30 March 2012
-
US Food and Drug Administration. Med Watch The FDA Safety Information and Adverse Event Reporting Program. Recombinant Human Growth Hormone (somatropin): Ongoing Safety Review - Possible Increased Risk of Death. Posted 12/22/2010. http://www.fda.gov/Safety/Med Watch/Safety Information/Safety Alerts for Human Medical Products/ucm237969.htm. Accessed: 30 March 2012.
-
-
-
-
241
-
-
0033305646
-
Current and potential drugs for treatment of obesity
-
Bray GA, Greenway FL. Current and potential drugs for treatment of obesity. Endocr Rev 1999; 20: 805-875.
-
(1999)
Endocr Rev
, vol.20
, pp. 805-875
-
-
Bray, G.A.1
Greenway, F.L.2
-
242
-
-
0033942504
-
Thyroid hormones and treatment of obesity
-
Krotkiewski M. Thyroid hormones and treatment of obesity. Int J Obes Relat Metab Disord 2000; 24(Suppl 2): S116-S119.
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, Issue.SUPPL. 2
-
-
Krotkiewski, M.1
-
244
-
-
1942453725
-
Selective activation of thyroid hormone signaling pathways by GC-1: A new approach to controlling cholesterol and body weight
-
Baxter JD, Webb P, Grover G, Scanlan TS. Selective activation of thyroid hormone signaling pathways by GC-1: a new approach to controlling cholesterol and body weight. Trends Endocrinol Metab 2004; 15: 154-157.
-
(2004)
Trends Endocrinol Metab
, vol.15
, pp. 154-157
-
-
Baxter, J.D.1
Webb, P.2
Grover, G.3
Scanlan, T.S.4
-
245
-
-
38649135692
-
The thyroid hormone mimetic compound KB2115 lowers plasma LDLcholesterol and stimulates bile acid synthesis without cardiac effects in humans
-
Berkenstam A, Kristensen J, Mellstrom K, Carlsson B, Malm J, Rehnmark S et al. The thyroid hormone mimetic compound KB2115 lowers plasma LDLcholesterol and stimulates bile acid synthesis without cardiac effects in humans. Proc Natl Acad Sci USA 2008; 105: 663-667.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 663-667
-
-
Berkenstam, A.1
Kristensen, J.2
Mellstrom, K.3
Carlsson, B.4
Malm, J.5
Rehnmark, S.6
-
246
-
-
0036783754
-
Effect of a 28-d treatment with L-796568, a novel beta (3)-adrenergic receptor agonist, on energy expenditure and body composition in obese men
-
Larsen TM, Toubro S, van Baak MA, Gottesdiener KM, Larson P, Saris WH et al. Effect of a 28-d treatment with L-796568, a novel beta(3)-adrenergic receptor agonist, on energy expenditure and body composition in obese men. Am J Clin Nutr 2002; 76: 780-788.
-
(2002)
Am J Clin Nutr
, vol.76
, pp. 780-788
-
-
Larsen, T.M.1
Toubro, S.2
Van Baak, M.A.3
Gottesdiener, K.M.4
Larson, P.5
Saris, W.H.6
-
247
-
-
33846961446
-
Lack of an effect of a novel beta3-adrenoceptor agonist, TAK-677, on energy metabo-lism in obese individuals: A double-blind, placebo-controlled randomized study
-
Redman LM, de Jonge L, Fang X, Gamlin B, Recker D, Greenway FL et al. Lack of an effect of a novel beta3-adrenoceptor agonist, TAK-677, on energy metabo-lism in obese individuals: a double-blind, placebo-controlled randomized study. J Clin Endocrinol Metab 2007; 92: 527-531.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 527-531
-
-
Redman, L.M.1
De Jonge, L.2
Fang, X.3
Gamlin, B.4
Recker, D.5
Greenway, F.L.6
-
248
-
-
0033653610
-
Effects of the two beta3-agonists, ZD7114 and ZD2079 on 24 hour energy expenditure and respiratory quotient in obese subjects
-
Buemann B, Toubro S, Astrup A. Effects of the two beta3-agonists, ZD7114 and ZD2079 on 24 hour energy expenditure and respiratory quotient in obese subjects. Int J Obes Relat Metab Disord 2000; 24: 1553-1560.
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, pp. 1553-1560
-
-
Buemann, B.1
Toubro, S.2
Astrup, A.3
-
249
-
-
0033763692
-
Thermogenic drugs as a strategy for treatment of obesity
-
Astrup A. Thermogenic drugs as a strategy for treatment of obesity. Endocrine 2000; 13: 207-212.
-
(2000)
Endocrine
, vol.13
, pp. 207-212
-
-
Astrup, A.1
-
250
-
-
0036261335
-
Herbal ephedra/caffeine for weight loss: A 6-month randomized safety and efficacy trial
-
Boozer CN, Daly PA, Homel P, Solomon JL, Blanchard D, Nasser JA et al. Herbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trial. Int J Obes Relat Metab Disord 2002; 26: 593-604.
-
(2002)
Int J Obes Relat Metab Disord
, vol.26
, pp. 593-604
-
-
Boozer, C.N.1
Daly, P.A.2
Homel, P.3
Solomon, J.L.4
Blanchard, D.5
Nasser, J.A.6
-
251
-
-
64749097994
-
Treatment of hypothalamic obesity with caffeine and ephedrine
-
Greenway FL, Bray GA. Treatment of hypothalamic obesity with caffeine and ephedrine. Endocr Pract 2008; 14: 697-703.
-
(2008)
Endocr Pract
, vol.14
, pp. 697-703
-
-
Greenway, F.L.1
Bray, G.A.2
-
252
-
-
0033646869
-
Safety and efficacy of treatment with an ephedrine/caffeine mixture. The first double-blind placebo-controlled pilot study in adolescents
-
Molnar D, Torok K, Erhardt E, Jeges S. Safety and efficacy of treatment with an ephedrine/caffeine mixture. The first double-blind placebo-controlled pilot study in adolescents. Int J Obes Relat Metab Disord 2000; 24: 1573-1578.
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, pp. 1573-1578
-
-
Molnar, D.1
Torok, K.2
Erhardt, E.3
Jeges, S.4
-
253
-
-
0345831912
-
Elec-trocardiographic and hemodynamic effects of a multicomponent dietary sup-plement containing ephedra and caffeine: A randomized controlled trial
-
Mc Bride BF, Karapanos AK, Krudysz A, Kluger J, Coleman CI, White CM. Elec-trocardiographic and hemodynamic effects of a multicomponent dietary sup-plement containing ephedra and caffeine: a randomized controlled trial. JAMA 2004; 291: 216-221.
-
(2004)
JAMA
, vol.291
, pp. 216-221
-
-
Mc Bride, B.F.1
Karapanos, A.K.2
Krudysz, A.3
Kluger, J.4
Coleman, C.I.5
White, C.M.6
-
254
-
-
0030728020
-
The effectiveness of long-term supplementation of carbohydrate, chromium, fibre and caffeine on weight maintenance
-
Pasman WJ, Westerterp-Plantenga MS, Saris WH. The effectiveness of long-term supplementation of carbohydrate, chromium, fibre and caffeine on weight maintenance. Int JObes Relat Metab Disord 1997; 21: 1143-1151.
-
(1997)
Int J Obes Relat Metab Disord
, vol.21
, pp. 1143-1151
-
-
Pasman, W.J.1
Westerterp-Plantenga, M.S.2
Saris, W.H.3
-
255
-
-
0027419299
-
Ephedrine, caffeine and aspirin: Safety and efficacy for treatment of human obesity
-
Daly PA, Krieger DR, Dulloo AG, Young JB, Landsberg L. Ephedrine, caffeine and aspirin: safety and efficacy for treatment of human obesity. Int J Obes Relat Metab Disord 1993; 17(Suppl 1): S73-S78.
-
(1993)
Int J Obes Relat Metab Disord
, vol.17
, Issue.SUPPL. 1
-
-
Daly, P.A.1
Krieger, D.R.2
Dulloo, A.G.3
Young, J.B.4
Landsberg, L.5
-
256
-
-
33749121586
-
Multinutrient supplement containing ephedra and caffeine causes weight loss and improves metabolic risk factors in obese women: A randomized controlled trial
-
Hackman RM, Havel PJ, Schwartz HJ, Rutledge JC, Watnik MR, Noceti EM et al. Multinutrient supplement containing ephedra and caffeine causes weight loss and improves metabolic risk factors in obese women: a randomized controlled trial. Int J Obes (Lond) 2006; 30: 1545-1556.
-
(2006)
Int J Obes (Lond)
, vol.30
, pp. 1545-1556
-
-
Hackman, R.M.1
Havel, P.J.2
Schwartz, H.J.3
Rutledge, J.C.4
Watnik, M.R.5
Noceti, E.M.6
-
257
-
-
0027483543
-
Safety and efficacy of long-term treatment with ephedrine, caffeine and an ephedrine/caffeine mixture
-
Toubro S, Astrup AV, Breum L, Quaade F. Safety and efficacy of long-term treatment with ephedrine, caffeine and an ephedrine/caffeine mixture. Int JObes Relat Metab Disord 1993; 17(Suppl 1): S69-S72.
-
(1993)
Int JObes Relat Metab Disord
, vol.17
, Issue.SUPPL. 1
-
-
Toubro, S.1
Astrup, A.V.2
Breum, L.3
Quaade, F.4
-
258
-
-
0030471122
-
The effect of ephedrine plus caffeine on smoking cessation and postcessation weight gain
-
Norregaard J, Jorgensen S, Mikkelsen KL, Tonnesen P, Iversen E, Sorensen T et al. The effect of ephedrine plus caffeine on smoking cessation and postcessation weight gain. Clin Pharmacol Ther 1996; 60: 679-686.
-
(1996)
Clin Pharmacol Ther
, vol.60
, pp. 679-686
-
-
Norregaard, J.1
Jorgensen, S.2
Mikkelsen, K.L.3
Tonnesen, P.4
Iversen, E.5
Sorensen, T.6
-
259
-
-
33845765350
-
Body fat loss achieved by stimulation of ther-mogenesis by a combination ofbioactivefood ingredients: A placebo-controlled, double-blind 8-week intervention in obese subjects
-
Belza A, Frandsen E, Kondrup J. Body fat loss achieved by stimulation of ther-mogenesis by a combination ofbioactivefood ingredients: a placebo-controlled, double-blind 8-week intervention in obese subjects. Int J Obes (Lond) 2007; 31: 121-130.
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 121-130
-
-
Belza, A.1
Frandsen, E.2
Kondrup, J.3
-
260
-
-
0035427921
-
The safety and efficacy of pharmaceutical and herbal caffeine and ephedrine use as a weight loss agent
-
Greenway FL. The safety and efficacy of pharmaceutical and herbal caffeine and ephedrine use as a weight loss agent. Obes Rev2001; 2: 199-211.
-
(2001)
Obes Rev
, vol.2
, pp. 199-211
-
-
Greenway, F.L.1
-
261
-
-
0026517115
-
Long-term weight control: The National Heart, Lung, and Blood Insti-tute funded multimodal intervention study
-
Weintraub M. Long-term weight control: the National Heart, Lung, and Blood Insti-tute funded multimodal intervention study. Clin Pharmacol Ther 1992; 51: 581-585.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 581-585
-
-
Weintraub, M.1
-
262
-
-
0026544763
-
Long-term weight control study IV (weeks 156to190). The second double-blind phase
-
Weintraub M, Sundaresan PR, Schuster B, Averbuch M, Stein EC, Cox C et al. Long-term weight control study. IV (weeks 156to190). The second double-blind phase. Clin Pharmacol Ther 1992; 51: 608-614.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 608-614
-
-
Weintraub, M.1
Sundaresan, P.R.2
Schuster, B.3
Averbuch, M.4
Stein, E.C.5
Cox, C.6
-
263
-
-
79954561234
-
Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): A randomised, placebo-controlled, phase 3 trial
-
Gadde KM, Allison DB, Ryan DH, Peterson CA, Troupin B, Schwiers ML et al. Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial. Lancet 2011; 377: 1341-1352.
-
(2011)
Lancet
, vol.377
, pp. 1341-1352
-
-
Gadde, K.M.1
Allison, D.B.2
Ryan, D.H.3
Peterson, C.A.4
Troupin, B.5
Schwiers, M.L.6
-
264
-
-
84856388467
-
Two-year sustained weight loss and metabolic benefits with controlled-release phenter-mine/topiramate in obese and overweight adults (SEQUEL): A randomized, pla-cebo-controlled, phase 3 extension study
-
Garvey WT, Ryan DH, Look M, Gadde KM, Allison DB, Peterson CA et al. Two-year sustained weight loss and metabolic benefits with controlled-release phenter-mine/topiramate in obese and overweight adults (SEQUEL): a randomized, pla-cebo-controlled, phase 3 extension study. Am J Clin Nutr 2012; 95: 297-308.
-
(2012)
Am J Clin Nutr
, vol.95
, pp. 297-308
-
-
Garvey, W.T.1
Ryan, D.H.2
Look, M.3
Gadde, K.M.4
Allison, D.B.5
Peterson, C.A.6
-
265
-
-
84856246606
-
Controlled-release phentermine/topiramate in severely obese adults: A rando-mized controlled trial (EQUIP)
-
Allison DB, Gadde KM, Garvey WT, Peterson CA, Schwiers ML, Najarian T et al. Controlled-release phentermine/topiramate in severely obese adults: a rando-mized controlled trial (EQUIP). Obesity (Silver Spring) 2011; 2: 330-342.
-
(2011)
Obesity (Silver Spring)
, vol.2
, pp. 330-342
-
-
Allison, D.B.1
Gadde, K.M.2
Garvey, W.T.3
Peterson, C.A.4
Schwiers, M.L.5
Najarian, T.6
-
266
-
-
0029919239
-
Adiposity and body mass indices in children: Benn's index and other weight for height indices as measures of relative adip-osity
-
Lazarus R, Baur L, Webb K, Blyth F. Adiposity and body mass indices in children: Benn's index and other weight for height indices as measures of relative adip-osity. Int J Obes Relat Metab Disord 1996; 20: 406-412.
-
(1996)
Int J Obes Relat Metab Disord
, vol.20
, pp. 406-412
-
-
Lazarus, R.1
Baur, L.2
Webb, K.3
Blyth, F.4
-
267
-
-
84872109172
-
-
FDA. approves weight-management drug Qsymia Accessed: 18 July 2012
-
FDA. approves weight-management drug Qsymia. http://www.fda.gov/News Events/Newsroom/Press Announcements/ucm312468.htm. Accessed: 18 July 2012.
-
-
-
-
268
-
-
34548549373
-
Combination therapy of zonisa-mide and bupropion for weight reduction in obese women: A preliminary, randomized, open-label study
-
Gadde KM, Yonish GM, Foust MS, Wagner HR. Combination therapy of zonisa-mide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study. J Clin Psychiatry 2007; 68: 1226-1229.
-
(2007)
J Clin Psychiatry
, vol.68
, pp. 1226-1229
-
-
Gadde, K.M.1
Yonish, G.M.2
Foust, M.S.3
Wagner, H.R.4
-
269
-
-
57949112266
-
Rational design of a combination medication forthetreatmentof obesity
-
Greenway FL, Whitehouse MJ, Guttadauria M, Anderson JW, Atkinson RL, Fujioka Ketal. Rational design of a combination medication forthetreatmentof obesity. Obesity (Silver Spring) 2009; 17: 30-39.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 30-39
-
-
Greenway, F.L.1
Whitehouse, M.J.2
Guttadauria, M.3
Anderson, J.W.4
Atkinson, R.L.5
Fujioka, K.6
-
270
-
-
0029665733
-
Impaired glucose toler-ance in patients with chronic hypoxic pulmonary disease
-
Hjalmarsen A, Aasebo U, Birkeland K, Sager G, Jorde R. Impaired glucose toler-ance in patients with chronic hypoxic pulmonary disease. Diabetes Metab 1996; 22: 37-42.
-
(1996)
Diabetes Metab
, vol.22
, pp. 37-42
-
-
Hjalmarsen, A.1
Aasebo, U.2
Birkeland, K.3
Sager, G.4
Jorde, R.5
-
272
-
-
77956904326
-
Weight loss with naltrexone SR/Bupropion SR combination therapy as an adjunct to behavior modification: The COR-BMOD trial
-
Wadden TA, Foreyt JP, Foster GD, Hill JO, Klein S, O'Neil PM et al. Weight loss with naltrexone SR/Bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial. Obesity (Silver Spring) 2011; 19: 110-120.
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 110-120
-
-
Wadden, T.A.1
Foreyt, J.P.2
Foster, G.D.3
Hill, J.O.4
Klein, S.5
O'Neil, P.M.6
-
273
-
-
77956057548
-
Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): A multicentre, randomised, double-blind, placebo-con-trolled, phase 3 trial
-
Greenway FL, Fujioka K, Plodkowski RA, Mudaliar S, Guttadauria M, Erickson J et al. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-con-trolled, phase 3 trial. Lancet 2010; 376: 595-605.
-
(2010)
Lancet
, vol.376
, pp. 595-605
-
-
Greenway, F.L.1
Fujioka, K.2
Plodkowski, R.A.3
Mudaliar, S.4
Guttadauria, M.5
Erickson, J.6
-
274
-
-
77956904326
-
Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to beha-vior modification: The COR-BMOD trial
-
Wadden TA, Foreyt JP, Foster GD, Hill JO, Klein S, O'Neil PM et al. Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to beha-vior modification: the COR-BMOD trial. Obesity (Silver Spring) 2011; 19: 110-120.
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 110-120
-
-
Wadden, T.A.1
Foreyt, J.P.2
Foster, G.D.3
Hill, J.O.4
Klein, S.5
O'Neil, P.M.6
-
275
-
-
70349757017
-
Contrave, a bupropion and naltrexone combination therapy for the potential treatment of obesity
-
Padwal R. Contrave, a bupropion and naltrexone combination therapy for the potential treatment of obesity. Curr Opin Investig Drugs 2009; 10: 1117-1125.
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 1117-1125
-
-
Padwal, R.1
-
276
-
-
84872108687
-
-
U.S. Food and Drug Administration Centerfor Drug Evaluation and Research. U.S. Food and Drug Administration Silver Spring, Maryland Accessed: 5 November 2011
-
Tran PT, Thomas A. Summary Minutes of the Endocrinologic and Metabolic Drugs Advisory Committee. U.S. Food and Drug Administration Centerfor Drug Evaluation and Research. U.S. Food and Drug Administration Silver Spring, Maryland, 2010, pp 1-8http://www.fda.gov/Advisory Committees/Committees Meeting Materials/ Drugs/Endocrinologicand Metabolic Drugs Advisory Committee/ucm191113. htm. Accessed: 5 November 2011.
-
(2010)
Summary Minutes of the Endocrinologic and Metabolic Drugs Advisory Committee
, pp. 1-8
-
-
Tran, P.T.1
Thomas, A.2
-
279
-
-
69749086148
-
Enhanced weight loss with pramlintide/metreleptin: An integrated neurohormonal approach to obesity pharmacotherapy
-
Ravussin E, Smith SR, Mitchell JA, Shringarpure R, Shan K, Maier H et al. Enhanced weight loss with pramlintide/metreleptin: an integrated neurohormonal approach to obesity pharmacotherapy. Obesity (Silver Spring) 2009; 17: 1736-1743.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 1736-1743
-
-
Ravussin, E.1
Smith, S.R.2
Mitchell, J.A.3
Shringarpure, R.4
Shan, K.5
Maier, H.6
-
280
-
-
44449175729
-
Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies
-
Roth JD, Roland BL, Cole RL, Trevaskis JL, Weyer C, Koda JE et al. Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies. Proc Natl Acad Sci USA 2008; 105: 7257-7262.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 7257-7262
-
-
Roth, J.D.1
Roland, B.L.2
Cole, R.L.3
Trevaskis, J.L.4
Weyer, C.5
Koda, J.E.6
-
281
-
-
49449114438
-
Antiobesity effects of the beta-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats
-
Roth JD, Trevaskis JL, Wilson J, Lei C, Athanacio J, Mack C et al. Antiobesity effects of the beta-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats. Int J Obes (Lond) 2008; 32: 1201-1210.
-
(2008)
Int J Obes (Lond)
, vol.32
, pp. 1201-1210
-
-
Roth, J.D.1
Trevaskis, J.L.2
Wilson, J.3
Lei, C.4
Athanacio, J.5
MacK, C.6
-
282
-
-
77956094570
-
Enhanced weight loss fol-lowing coadministration of pramlintide with sibutramine or phentermine in a multicenter trial
-
Aronne LJ, Halseth AE, Burns CM, Miller S, Shen LZ. Enhanced weight loss fol-lowing coadministration of pramlintide with sibutramine or phentermine in a multicenter trial. Obesity (Silver Spring) 2010; 18: 1739-1746.
-
(2010)
Obesity (Silver Spring)
, vol.18
, pp. 1739-1746
-
-
Aronne, L.J.1
Halseth, A.E.2
Burns, C.M.3
Miller, S.4
Shen, L.Z.5
-
283
-
-
78049337953
-
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
-
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010; 42: 937-948.
-
(2010)
Nat Genet
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
Monda, K.L.4
Thorleifsson, G.5
Jackson, A.U.6
-
284
-
-
78049249912
-
Genetic susceptibility to obesity and related traits in childhood and adolescence: Influ-ence of loci identified by genome-wide association studies
-
den Hoed M, Ekelund U, Brage S, Grontved A, Zhao JH, Sharp SJ et al. Genetic susceptibility to obesity and related traits in childhood and adolescence: influ-ence of loci identified by genome-wide association studies. Diabetes 2010; 59: 2980-2988.
-
(2010)
Diabetes
, vol.59
, pp. 2980-2988
-
-
Den Hoed, M.1
Ekelund, U.2
Brage, S.3
Grontved, A.4
Zhao, J.H.5
Sharp, S.J.6
-
285
-
-
81855221882
-
Role of BMI-associated loci identified in GWAS meta-analyses in the context of common child-hood obesity in European Americans
-
Zhao J, Bradfield JP, Zhang H, Sleiman PM, Kim CE, Glessner JT et al. Role of BMI-associated loci identified in GWAS meta-analyses in the context of common child-hood obesity in European Americans. Obesity (Silver Spring) 2011; 19: 2436-2439.
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 2436-2439
-
-
Zhao, J.1
Bradfield, J.P.2
Zhang, H.3
Sleiman, P.M.4
Kim, C.E.5
Glessner, J.T.6
-
286
-
-
70449851433
-
Reappraisal of European guidelines on hypertension management: A European Society of Hypertension Task Force document
-
Mancia G, Laurent S, Agabiti-Rosei E, Ambrosioni E, Burnier M, Caulfield MJ et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document.J Hypertens 2009; 27: 2121-2158.
-
(2009)
J Hypertens
, vol.27
, pp. 2121-2158
-
-
Mancia, G.1
Laurent, S.2
Agabiti-Rosei, E.3
Ambrosioni, E.4
Burnier, M.5
Caulfield, M.J.6
-
287
-
-
79955039550
-
Attrition in paediatric weight management: A review of the literature and new directions
-
Skelton JA, Beech BM. Attrition in paediatric weight management: a review of the literature and new directions. Obes Rev 2011; 12: e273-e281.
-
(2011)
Obes Rev
, vol.12
-
-
Skelton, J.A.1
Beech, B.M.2
-
288
-
-
77950189829
-
CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials
-
Schulz KF, Altman DG, Moher D. CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. Bmj 2010; 340: c332.
-
(2010)
Bmj
, vol.340
-
-
Schulz, K.F.1
Altman, D.G.2
Moher, D.3
-
289
-
-
15544363770
-
What is the best measure of adiposity change in growing children: BMI, BMI %, BMI z-score or BMI centile?
-
Cole TJ, Faith MS, Pietrobelli A, Heo M. What is the best measure of adiposity change in growing children: BMI, BMI %, BMI z-score or BMI centile? Eur J Clin Nutr 2005; 59: 419-425.
-
(2005)
Eur J Clin Nutr
, vol.59
, pp. 419-425
-
-
Cole, T.J.1
Faith, M.S.2
Pietrobelli, A.3
Heo, M.4
-
290
-
-
33845519508
-
Adiposity in adolescents: Change in actual BMI works better than change in BMI z score for longitudinal studies
-
Berkey CS, Colditz GA. Adiposity in adolescents: change in actual BMI works better than change in BMI z score for longitudinal studies. Ann Epidemiol 2007; 17: 44-50.
-
(2007)
Ann Epidemiol
, vol.17
, pp. 44-50
-
-
Berkey, C.S.1
Colditz, G.A.2
-
291
-
-
85047695511
-
Pharmacotherapy for obesity: A quantitative analysis offour decades ofpublished randomized clinical trials
-
Haddock CK, Poston WS, Dill PL, Foreyt JP, Ericsson M. Pharmacotherapy for obesity: a quantitative analysis offour decades ofpublished randomized clinical trials. Int J Obes Relat Metab Disord 2002; 26: 262-273.
-
(2002)
Int J Obes Relat Metab Disord
, vol.26
, pp. 262-273
-
-
Haddock, C.K.1
Poston, W.S.2
Dill, P.L.3
Foreyt, J.P.4
Ericsson, M.5
-
292
-
-
34648836960
-
Weight-loss outcomes: A systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up
-
Franz MJ, Van Wormer JJ, Crain AL, Boucher JL, Histon T, Caplan W et al. Weight-loss outcomes: a systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up. J Am Diet Assoc 2007; 107: 1755-1767.
-
(2007)
J Am Diet Assoc
, vol.107
, pp. 1755-1767
-
-
Franz, M.J.1
Van Wormer, J.J.2
Crain, A.L.3
Boucher, J.L.4
Histon, T.5
Caplan, W.6
-
293
-
-
62449129181
-
Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD-1 SU)
-
Marre M, Shaw J, Brandle M, Bebakar WM, Kamaruddin NA, Strand J et al. Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD-1 SU). Diabet Med 2009; 26: 268-278.
-
(2009)
Diabet Med
, vol.26
, pp. 268-278
-
-
Marre, M.1
Shaw, J.2
Brandle, M.3
Bebakar, W.M.4
Kamaruddin, N.A.5
Strand, J.6
-
294
-
-
67649666737
-
Liraglutide once a day versus exenatide twice a day for type 2 diabetes: A 26-week ran-domised, parallel-group, multinational, open-label trial (LEAD-6)
-
Buse JB, Rosenstock J, Sesti G, Schmidt WE, Montanya E, Brett JH et al. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week ran-domised, parallel-group, multinational, open-label trial (LEAD-6). Lancet 2009; 374: 39-47.
-
(2009)
Lancet
, vol.374
, pp. 39-47
-
-
Buse, J.B.1
Rosenstock, J.2
Sesti, G.3
Schmidt, W.E.4
Montanya, E.5
Brett, J.H.6
-
295
-
-
34548016826
-
Sitagliptin: A novel drug for the treatment of type 2 diabetes
-
Choy M, Lam S. Sitagliptin: a novel drug for the treatment of type 2 diabetes. Cardiol Rev 2007; 15: 264-271.
-
(2007)
Cardiol Rev
, vol.15
, pp. 264-271
-
-
Choy, M.1
Lam, S.2
-
296
-
-
80051872773
-
Efficacy and safety of sitagliptin and the fixed-dose combination of sitagliptin and metformin vs. pioglitazone in drug-naive patients with type 2 diabetes
-
Perez-Monteverde A, Seck T, Xu L, Lee MA, Sisk CM, Williams-Herman DE et al. Efficacy and safety of sitagliptin and the fixed-dose combination of sitagliptin and metformin vs. pioglitazone in drug-naive patients with type 2 diabetes. Int J Clin Pract 2011; 65: 930-938.
-
(2011)
Int J Clin Pract
, vol.65
, pp. 930-938
-
-
Perez-Monteverde, A.1
Seck, T.2
Xu, L.3
Lee, M.A.4
Sisk, C.M.5
Williams-Herman, D.E.6
-
297
-
-
34547639141
-
Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acid concentration in obese males
-
Sloth B, Davidsen L, Holst JJ, Flint A, Astrup A. Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acid concentration in obese males. Am J Physiol Endocrinol Metab 2007; 293: E604-E609.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
-
-
Sloth, B.1
Davidsen, L.2
Holst, J.J.3
Flint, A.4
Astrup, A.5
-
298
-
-
34249862701
-
Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults
-
Gantz I, Erondu N, Mallick M, Musser B, Krishna R, Tanaka WK et al. Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults. J Clin Endocrinol Metab 2007; 92: 1754-1757.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1754-1757
-
-
Gantz, I.1
Erondu, N.2
Mallick, M.3
Musser, B.4
Krishna, R.5
Tanaka, W.K.6
-
299
-
-
77953857048
-
Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: A randomised, double-blind, placebo-controlled trial
-
Bailey CJ, Gross JL, Pieters A, Bastien A, List JF. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial. Lancet 2010; 375: 2223-2233.
-
(2010)
Lancet
, vol.375
, pp. 2223-2233
-
-
Bailey, C.J.1
Gross, J.L.2
Pieters, A.3
Bastien, A.4
List, J.F.5
|