메뉴 건너뛰기




Volumn 39, Issue 1, 2010, Pages 69-79

Pharmacologic Therapies for Obesity

Author keywords

Obesity treatment; Pharmacology treatments obesity; Weight loss medication

Indexed keywords

1,25 DIHYDROXYERGOCALCIFEROL; 2,4 THIAZOLIDINEDIONE DERIVATIVE; AMFEBUTAMONE; AMFEPRAMONE; ANTIHYPERTENSIVE AGENT; BENZPHETAMINE; CLOZAPINE; DEXFENFLURAMINE; EPHEDRINE; EXENDIN 4; FENFLURAMINE; LORCASERIN; METFORMIN; MONOAMINE OXIDASE INHIBITOR; NALTREXONE; OLANZAPINE; PHENDIMETRAZINE; PHENTERMINE; PHENYLPROPANOLAMINE; PLACEBO; PSYCHOTROPIC AGENT; SEROTONIN UPTAKE INHIBITOR; SIBUTRAMINE; STEROID HORMONE; SULFONYLUREA; TETRAHYDROLIPSTATIN; TOPIRAMATE; UNINDEXED DRUG; VALPROATE SEMISODIUM; ZONISAMIDE;

EID: 77349115193     PISSN: 08898553     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gtc.2010.01.001     Document Type: Review
Times cited : (77)

References (39)
  • 1
    • 56249146307 scopus 로고    scopus 로고
    • Medications for weight reduction
    • Bray G.A. Medications for weight reduction. Endocrinol Metab Clin North Am 37 (2008) 923-942
    • (2008) Endocrinol Metab Clin North Am , vol.37 , pp. 923-942
    • Bray, G.A.1
  • 2
    • 64349117818 scopus 로고    scopus 로고
    • Pharmacotherapy of obesity: emerging drugs and targets
    • Chakrabarti R. Pharmacotherapy of obesity: emerging drugs and targets. Expert Opin Ther Targets 13 (2009) 195-207
    • (2009) Expert Opin Ther Targets , vol.13 , pp. 195-207
    • Chakrabarti, R.1
  • 3
    • 55849122229 scopus 로고    scopus 로고
    • Lifestyle and pharmacological approaches to weight loss: efficacy and safety
    • Bray G.A. Lifestyle and pharmacological approaches to weight loss: efficacy and safety. J Clin Endocrinol Metab 93 (2008) S81-S88
    • (2008) J Clin Endocrinol Metab , vol.93
    • Bray, G.A.1
  • 4
    • 0346250180 scopus 로고    scopus 로고
    • Long-term pharmacotherapy for overweight and obesity: a systematic review and meta-analysis of randomized controlled trials
    • Padwal R., Li S.K., and Lau D.C. Long-term pharmacotherapy for overweight and obesity: a systematic review and meta-analysis of randomized controlled trials. Int J Obes Relat Metab Disord 27 (2003) 1437-1446
    • (2003) Int J Obes Relat Metab Disord , vol.27 , pp. 1437-1446
    • Padwal, R.1    Li, S.K.2    Lau, D.C.3
  • 5
    • 34249821944 scopus 로고    scopus 로고
    • Pharmacological treatment of the overweight patient
    • Bray G.A., and Greenway F.L. Pharmacological treatment of the overweight patient. Pharmacol Rev 59 (2007) 151-184
    • (2007) Pharmacol Rev , vol.59 , pp. 151-184
    • Bray, G.A.1    Greenway, F.L.2
  • 6
  • 7
    • 0032162184 scopus 로고    scopus 로고
    • Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults-the evidence report. National Institutes of Health
    • Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults-the evidence report. National Institutes of Health. Obes Res 6 Suppl 2 (1998) 51S-209S
    • (1998) Obes Res , vol.6 , Issue.SUPPL. 2
  • 8
    • 0037279371 scopus 로고    scopus 로고
    • Weight management and current options in pharmacotherapy: orlistat and sibutramine
    • Leung W.Y., Thomas G.N., Chan J.C., et al. Weight management and current options in pharmacotherapy: orlistat and sibutramine. Clin Ther 25 (2003) 58-80
    • (2003) Clin Ther , vol.25 , pp. 58-80
    • Leung, W.Y.1    Thomas, G.N.2    Chan, J.C.3
  • 9
    • 0036778351 scopus 로고    scopus 로고
    • Bupropion SR vs. placebo for weight loss in obese patients with depressive symptoms
    • Jain A.K., Kaplan R.A., Gadde K.M., et al. Bupropion SR vs. placebo for weight loss in obese patients with depressive symptoms. Obes Res 10 (2002) 1049-1056
    • (2002) Obes Res , vol.10 , pp. 1049-1056
    • Jain, A.K.1    Kaplan, R.A.2    Gadde, K.M.3
  • 10
    • 23844436916 scopus 로고    scopus 로고
    • Metformin and weight loss in obese women with polycystic ovary syndrome: comparison of doses
    • Harborne L.R., Sattar N., Norman J.E., et al. Metformin and weight loss in obese women with polycystic ovary syndrome: comparison of doses. J Clin Endocrinol Metab 90 (2005) 4593-4598
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 4593-4598
    • Harborne, L.R.1    Sattar, N.2    Norman, J.E.3
  • 11
    • 40749161446 scopus 로고    scopus 로고
    • Exenatide as a treatment for diabetes and obesity: implications for cardiovascular risk reduction
    • Mafong D.D., and Henry R.R. Exenatide as a treatment for diabetes and obesity: implications for cardiovascular risk reduction. Curr Atheroscler Rep 10 (2008) 55-60
    • (2008) Curr Atheroscler Rep , vol.10 , pp. 55-60
    • Mafong, D.D.1    Henry, R.R.2
  • 12
    • 15544384618 scopus 로고    scopus 로고
    • Topiramate: a new potential pharmacological treatment for obesity
    • Astrup A., and Toubro S. Topiramate: a new potential pharmacological treatment for obesity. Obes Res 12 Suppl (2004) 167S-173S
    • (2004) Obes Res , vol.12 , Issue.SUPPL
    • Astrup, A.1    Toubro, S.2
  • 13
    • 0038516857 scopus 로고    scopus 로고
    • Zonisamide for weight loss in obese adults: a randomized controlled trial
    • Gadde K.M., Franciscy D.M., Wagner II H.R., et al. Zonisamide for weight loss in obese adults: a randomized controlled trial. JAMA 289 (2003) 1820-1825
    • (2003) JAMA , vol.289 , pp. 1820-1825
    • Gadde, K.M.1    Franciscy, D.M.2    Wagner II, H.R.3
  • 14
    • 34247891784 scopus 로고    scopus 로고
    • Drug treatment of the overweight patient
    • Bray G.A., and Ryan D.H. Drug treatment of the overweight patient. Gastroenterology 132 (2007) 2239-2252
    • (2007) Gastroenterology , vol.132 , pp. 2239-2252
    • Bray, G.A.1    Ryan, D.H.2
  • 15
    • 49649101096 scopus 로고    scopus 로고
    • Head-to-head studies evaluating efficacy of pharmaco-therapy for obesity: a systematic review and meta-analysis
    • Neovius M., Johansson K., and Rossner S. Head-to-head studies evaluating efficacy of pharmaco-therapy for obesity: a systematic review and meta-analysis. Obes Rev 9 (2008) 420-427
    • (2008) Obes Rev , vol.9 , pp. 420-427
    • Neovius, M.1    Johansson, K.2    Rossner, S.3
  • 16
    • 0030876952 scopus 로고    scopus 로고
    • Valvular heart disease associated with fenfluramine-phentermine
    • Connolly H.M., Crary J.L., McGoon M.D., et al. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med 337 (1997) 581-588
    • (1997) N Engl J Med , vol.337 , pp. 581-588
    • Connolly, H.M.1    Crary, J.L.2    McGoon, M.D.3
  • 17
    • 0037133534 scopus 로고    scopus 로고
    • Regression and progression of valvulopathy associated with fenfluramine and phentermine
    • Dahl C.F., and Allen M.R. Regression and progression of valvulopathy associated with fenfluramine and phentermine. Ann Intern Med 136 (2002) 489
    • (2002) Ann Intern Med , vol.136 , pp. 489
    • Dahl, C.F.1    Allen, M.R.2
  • 18
    • 0035218345 scopus 로고    scopus 로고
    • Aortic and mitral fenfluramine-phentermine valvulopathy in 64 patients treated with anorectic agents
    • Volmar K.E., and Hutchins G.M. Aortic and mitral fenfluramine-phentermine valvulopathy in 64 patients treated with anorectic agents. Arch Pathol Lab Med 125 (2001) 1555-1561
    • (2001) Arch Pathol Lab Med , vol.125 , pp. 1555-1561
    • Volmar, K.E.1    Hutchins, G.M.2
  • 19
    • 57749204131 scopus 로고    scopus 로고
    • Cost-effectiveness of pharmacological anti-obesity treatments: a systematic review
    • Neovius M., and Narbro K. Cost-effectiveness of pharmacological anti-obesity treatments: a systematic review. Int J Obes (Lond) 32 (2008) 1752-1763
    • (2008) Int J Obes (Lond) , vol.32 , pp. 1752-1763
    • Neovius, M.1    Narbro, K.2
  • 20
    • 27844487932 scopus 로고    scopus 로고
    • Randomized trial of lifestyle modification and pharmacotherapy for obesity
    • Wadden T.A., Berkowitz R.I., Womble L.G., et al. Randomized trial of lifestyle modification and pharmacotherapy for obesity. N Engl J Med 353 (2005) 2111-2120
    • (2005) N Engl J Med , vol.353 , pp. 2111-2120
    • Wadden, T.A.1    Berkowitz, R.I.2    Womble, L.G.3
  • 21
    • 40349113439 scopus 로고    scopus 로고
    • Are non-prescription medications needed for weight control?
    • Bray G.A. Are non-prescription medications needed for weight control?. Obesity (Silver Spring) 16 (2008) 509-514
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 509-514
    • Bray, G.A.1
  • 22
    • 34250842579 scopus 로고    scopus 로고
    • Weight loss and metabolic effects of topiramate in overweight and obese type 2 diabetic patients: randomized double-blind placebo-controlled trial
    • Eliasson B., Gudbjornsdottir S., Cederholm J., et al. Weight loss and metabolic effects of topiramate in overweight and obese type 2 diabetic patients: randomized double-blind placebo-controlled trial. Int J Obes (Lond) 31 (2007) 1140-1147
    • (2007) Int J Obes (Lond) , vol.31 , pp. 1140-1147
    • Eliasson, B.1    Gudbjornsdottir, S.2    Cederholm, J.3
  • 23
    • 56149124659 scopus 로고    scopus 로고
    • Sustained weight loss following 12-month pramlintide treatment as an adjunct to lifestyle intervention in obesity
    • Smith S.R., Aronne L.J., Burns C.M., et al. Sustained weight loss following 12-month pramlintide treatment as an adjunct to lifestyle intervention in obesity. Diabetes Care 31 (2008) 1816-1823
    • (2008) Diabetes Care , vol.31 , pp. 1816-1823
    • Smith, S.R.1    Aronne, L.J.2    Burns, C.M.3
  • 24
    • 68749091398 scopus 로고    scopus 로고
    • Current pharmacotherapeutic concepts for the treatment of obesity in adults
    • Idelevich E., Kirch W., and Schindler C. Current pharmacotherapeutic concepts for the treatment of obesity in adults. Ther Adv Cardiovasc Dis 3 (2009) 75-90
    • (2009) Ther Adv Cardiovasc Dis , vol.3 , pp. 75-90
    • Idelevich, E.1    Kirch, W.2    Schindler, C.3
  • 25
    • 68949205198 scopus 로고    scopus 로고
    • Promising strategies for obesity pharmacotherapy: melanocortin-4 (MC-4) receptor agonists and melanin concentrating hormone (MCH) receptor-1 antagonists
    • Jeon M.K., and Cheon H.G. Promising strategies for obesity pharmacotherapy: melanocortin-4 (MC-4) receptor agonists and melanin concentrating hormone (MCH) receptor-1 antagonists. Curr Top Med Chem 9 (2009) 504-538
    • (2009) Curr Top Med Chem , vol.9 , pp. 504-538
    • Jeon, M.K.1    Cheon, H.G.2
  • 26
    • 65549160462 scopus 로고    scopus 로고
    • Recent advances in obesity pharmacotherapy
    • Mayer M.A., Hocht C., Puyo A., et al. Recent advances in obesity pharmacotherapy. Curr Clin Pharmacol 4 (2009) 53-61
    • (2009) Curr Clin Pharmacol , vol.4 , pp. 53-61
    • Mayer, M.A.1    Hocht, C.2    Puyo, A.3
  • 27
    • 68149166586 scopus 로고    scopus 로고
    • Naltrexone for the treatment of obesity: review and update
    • Lee M.W., and Fujioka K. Naltrexone for the treatment of obesity: review and update. Expert Opin Pharmacother 10 (2009) 1841-1845
    • (2009) Expert Opin Pharmacother , vol.10 , pp. 1841-1845
    • Lee, M.W.1    Fujioka, K.2
  • 28
    • 71849113008 scopus 로고    scopus 로고
    • Comparison of combined bupropion and naltrexone therapy for obesity with monotherapy and placebo
    • Greenway F.L., Dunayevich E., Tollefson G., et al. Comparison of combined bupropion and naltrexone therapy for obesity with monotherapy and placebo. J Clin Endocrinol Metab 94 (2009) 4898-4906
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 4898-4906
    • Greenway, F.L.1    Dunayevich, E.2    Tollefson, G.3
  • 29
    • 70349757017 scopus 로고    scopus 로고
    • Contrave, a bupropion and naltrexone combination therapy for the potential treatment of obesity
    • Padwal R. Contrave, a bupropion and naltrexone combination therapy for the potential treatment of obesity. Curr Opin Investig Drugs 10 (2009) 1117-1125
    • (2009) Curr Opin Investig Drugs , vol.10 , pp. 1117-1125
    • Padwal, R.1
  • 30
    • 67649641596 scopus 로고    scopus 로고
    • Bupropion and naltrexone: a review of their use individually and in combination for the treatment of obesity
    • Plodkowski R.A., Nguyen Q., Sundaram U., et al. Bupropion and naltrexone: a review of their use individually and in combination for the treatment of obesity. Expert Opin Pharmacother 10 (2009) 1069-1081
    • (2009) Expert Opin Pharmacother , vol.10 , pp. 1069-1081
    • Plodkowski, R.A.1    Nguyen, Q.2    Sundaram, U.3
  • 31
    • 84874677540 scopus 로고    scopus 로고
    • Drugs in the pipeline for the obesity market
    • Klonoff D.C., and Greenway F. Drugs in the pipeline for the obesity market. J Diabetes Sci Technol 2 (2008) 913-918
    • (2008) J Diabetes Sci Technol , vol.2 , pp. 913-918
    • Klonoff, D.C.1    Greenway, F.2
  • 32
  • 33
    • 69249217866 scopus 로고    scopus 로고
    • Drug treatment of obesity: established and emerging therapies
    • Isidro M.L., and Cordido F. Drug treatment of obesity: established and emerging therapies. Mini Rev Med Chem 9 (2009) 664-673
    • (2009) Mini Rev Med Chem , vol.9 , pp. 664-673
    • Isidro, M.L.1    Cordido, F.2
  • 34
    • 0026544763 scopus 로고
    • Long-term weight control study. IV (weeks 156 to 190). The second double-blind phase
    • Weintraub M., Sundaresan P.R., Schuster B., et al. Long-term weight control study. IV (weeks 156 to 190). The second double-blind phase. Clin Pharmacol Ther 51 (1992) 608-614
    • (1992) Clin Pharmacol Ther , vol.51 , pp. 608-614
    • Weintraub, M.1    Sundaresan, P.R.2    Schuster, B.3
  • 35
    • 0037187883 scopus 로고    scopus 로고
    • Implementation of the comprehensive methamphetamine control of 1996; regulation of pseudoephedrine, phenylpropanolamine, and combination ephedrine drug products and reports of certain transactions to nonregulated persons. Final rule
    • Drug Enforcement Administration (DEA), Justice. Implementation of the comprehensive methamphetamine control of 1996; regulation of pseudoephedrine, phenylpropanolamine, and combination ephedrine drug products and reports of certain transactions to nonregulated persons. Final rule. Fed Regist 67 (2002) 14853-14862
    • (2002) Fed Regist , vol.67 , pp. 14853-14862
    • Drug Enforcement Administration (DEA), Justice,1
  • 36
    • 1542349221 scopus 로고    scopus 로고
    • Final rule declaring dietary supplements containing ephedrine alkaloids adulterated because they present an unreasonable risk. Final rule
    • Food and Drug Administration, HHS. Final rule declaring dietary supplements containing ephedrine alkaloids adulterated because they present an unreasonable risk. Final rule. Fed Regist 69 (2004) 6787-6854
    • (2004) Fed Regist , vol.69 , pp. 6787-6854
    • Food and Drug Administration, HHS,1
  • 37
    • 44049089150 scopus 로고    scopus 로고
    • Molecular pharmacodynamics, clinical therapeutics, and pharmacokinetics of topiramate
    • Shank R.P., and Maryanoff B.E. Molecular pharmacodynamics, clinical therapeutics, and pharmacokinetics of topiramate. CNS Neurosci Ther 14 (2008) 120-142
    • (2008) CNS Neurosci Ther , vol.14 , pp. 120-142
    • Shank, R.P.1    Maryanoff, B.E.2
  • 38
    • 5044242948 scopus 로고    scopus 로고
    • Bariatric surgery: a systematic review and meta-analysis
    • Buchwald H., Avidor Y., Braunwald E., et al. Bariatric surgery: a systematic review and meta-analysis. JAMA 292 (2004) 1724-1737
    • (2004) JAMA , vol.292 , pp. 1724-1737
    • Buchwald, H.1    Avidor, Y.2    Braunwald, E.3
  • 39
    • 57949100659 scopus 로고    scopus 로고
    • Capacity for physical activity predicts weight loss after Roux-en-Y gastric bypass
    • Hatoum I.J., Stein H.K., Merrifield B.F., et al. Capacity for physical activity predicts weight loss after Roux-en-Y gastric bypass. Obesity (Silver Spring) 17 (2009) 92-99
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 92-99
    • Hatoum, I.J.1    Stein, H.K.2    Merrifield, B.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.