Effects of exogenous leptin on satiety and satiation in patients with lipodystrophy and leptin insufficiency

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 9, 2004, Pages 4258-4263

  McDuffie, Jennifer R ^a   Riggs, Patti A ^b   Calis, Karim A ^b   Freedman, Renee J ^a   Oral, Elif A ^c   DePaoli, Alex M ^d   Yanovski, Jack A ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

A 100; ACARBOSE; ATORVASTATIN; ENALAPRIL; FENOFIBRATE; GEMFIBROZIL; INSULIN; LEPTIN; LISINOPRIL; METFORMIN; PIOGLITAZONE; RECOMBINANT LEPTIN; RECOMBINANT METHIONYLLEPTIN; ROSIGLITAZONE; TETRAHYDROLIPSTATIN; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET RESTRICTION; DISEASE MODEL; DRUG EFFECT; EATING DISORDER; FEMALE; FOOD INTAKE; HORMONE DEFICIENCY; HUMAN; HUNGER; LIPODYSTROPHY; PRIORITY JOURNAL; SATIETY;

ADOLESCENT; ADULT; ENERGY METABOLISM; FEMALE; HUMANS; LEPTIN; LIPODYSTROPHY; SATIATION;

EID: 4544286790     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-031868     Document Type: Article

References (29)

1. Petersen KF, Oral EA, Dufour S, Befroy D, Ariyan C, Yu C, Cline GW, DePaoli AM, Taylor SI, Corden P, Shulman GJ 2002 Leprin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. J Clin Invest 109:1345-1350
2. Havel PJ 2002 Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin. Curr Opin Lipidol 13:51-59
3. Havel PJ, Townsend R, Chaump L, Teff K 1999 High-fat meals reduce 24-h circulating leptin concentrations in women. Diabetes 48:334-341
4. Weigle DS, Cummings DE, Newby PD, Breen PA, Frayo RS, Matthys CC, Callahan HS, Purnell JQ 2003 Roles of leptin and ghrelin in the loss of body weight caused by a low fat, high carbohydrate diet. J Clin Endocrinol Metab 88:1577-1586
5. Schwartz MW 2001 Brain pathways controlling food intake and body weight. Exp Biol Med 226:978-981
6. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM 1995 Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546
7. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F 1995 Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543
8. Farooqi IS, Jebb SA, Langmack G, Lawrence E, Cheetham CH, Prentice AM, Hughes JA, McCamish MA, O'Rahilly S 1999 Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med 341:879-884
9. Farooqi IS, Matarese G, Lord GM, Keogh JM, Lawrence E, Agwu C, Sanna V, Jebb SA, Perna F, Fontana S, Lechler RI, DePaoli AM, O'Rahilly S 2002 Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 110:1093-1303
10. Blundell JE, Goodson S, Halford JC 2001 Regulation of appetite: role of leptin in signalling systems for drive and satiety. Int J Obes Relat Metab Disord 25 Suppl 1:S29-S34
11. Rolls BJ, Hetherington M, Burley VJ 1988 The specificity of satiety: the influence of foods of different macronutrient content on the development of satiety. Physiol Behav 43:145-153
12. Heini AF, Lara-Castro C, Kirk KA, Considine RV, Caro JF, Weinsier RL 1998 Association of leptin and hunger-satiety ratings in obese women. Int J Obes Relat Metab Disord 22:1084-1087
13. Keim NL, Stern JS, Havel PJ 1998 Relation between circulating leptin concentrations and appetite during a prolonged, moderate energy deficit in women. Am J Clin Nutr 68:794-801
14. Peters AL, Schriger DL 1998 The new diagnostic criteria for diabetes: the impact on management of diabetes and macrovascular risk factors. Am J Med 105:155-193
15. Oral EA, Simha V, Ruiz E, Andewelt A, Premkumar A, Snell P, Wagner AJ, DePaoli AM, Reitman ML, Taylor SI, Gorden P, Garg A 2002 Leptin-replacement therapy for lipodystrophy. N Engl J Med 346:570-578
16. Hadigan CM, Kissileff HR, Walsh BT 1989 Patterns of food selection during meals in women with bulimia. Am J Clin Nutr 50:759-766
17. Hetherington MM, Altemus M, Nelson ML, Bernat AS, Gold PW 1994 Eating behavior in bulimia nervosa: multiple meal analyses. Am J Clin Nutr 60: 864-873
18. Sepple CP, Read NW 1989 Gastrointestinal correlates of the development of hunger in man. Appetite 13:183-191
19. Kissileff HR, Walsh BT, Kral JG, Cassidy SM 1986 Laboratory studies of eating behavior in women with bulimia. Physiol Behav 38:563-570
20. Hochberg Y 1988 A sharper Bonferroni procedure for multiple tests of significance. Biometrika 75:800-803
21. 2000 Position of the American Dietetic Association, Dietitians of Canada, and the American College of Sports Medicine: Nutrition and athletic performance. J Am Diet Assoc 100:1543-1556
22. Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, Weigle DS 2001 A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 50:1714-1719
23. Barazzoni R, Zanetti M, Stebel M, Biolo G, Cattin L, Guarnieri G 2003 Hyperleptinemia prevents increased plasma ghrelin concentration during short-term moderate caloric restriction in rats. Gastroenterology 124:1188-1192
24. Barrachina MD, Martinez V, Wang L, Wei JY, Tache Y 1997 Synergistic interaction between leptin and cholecystokinin to reduce short-term food intake in lean mice. Proc Natl Acad Sci USA 94:10455-10460
25. McMinn JE, Sindelar DK, Havel PJ, Schwartz MW 2000 Leptin deficiency induced by fasting impairs the satiety response to cholecystokinin. Endocrinology 141:4442-4448
26. Baskin DG, Blevins JE, Schwartz MW 2001 How the brain regulates food intake and body weight: the role of leptin. J Pediatr Endocrinol Metab 14(Suppl 6):1417-1429
27. Romon M, Lebel P, Velly C, Marecaux N, Fruchart JC, Dallongeville J 1999 Leptin response to carbohydrate or fat meal and association with subsequent satiety and energy intake. Am J Physiol 277:E855-E861
28. Matzinger D, Degen L, Drewe J, Meuli J, Duebendorfer R, Ruckstuhl N, D'Amato M, Rovati L, Beglinger C 2000 The role of long chain fatty acids in regulating food intake and cholecystokinin release in humans. Gut 46:688-693
29. Jequier E 2002 Leptin signaling, adiposity, and energy balance. Ann NY Acad Sci 967:379-388