-
1
-
-
0018621289
-
Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons
-
Woods SC, Lotter EC, McKay LD, Porte D Jr. Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons. Nature 282:503-505, 1979.
-
(1979)
Nature
, vol.282
, pp. 503-505
-
-
Woods, S.C.1
Lotter, E.C.2
McKay, L.D.3
Porte D., Jr.4
-
2
-
-
0032577376
-
Signals that regulate food intake and energy homeostasis
-
Woods S, Seeley RJ, Porte D Jr., Schwartz MW. Signals that regulate food intake and energy homeostasis. Science 280:1378-1383, 1998.
-
(1998)
Science
, vol.280
, pp. 1378-1383
-
-
Woods, S.1
Seeley, R.J.2
Porte D., Jr.3
Schwartz, M.W.4
-
3
-
-
0033857975
-
Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs
-
Kaiyala KJ, Prigeon RL, Kahn SE, Woods SC, Schwartz MW. Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs. Diabetes 49:1525-1533, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 1525-1533
-
-
Kaiyala, K.J.1
Prigeon, R.L.2
Kahn, S.E.3
Woods, S.C.4
Schwartz, M.W.5
-
4
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432, 1994.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
5
-
-
0015792424
-
Effects of parabiosis of obese with diabetes and normal mice
-
Coleman DL. Effects of parabiosis of obese with diabetes and normal mice. Diabetologia 9:294-298, 1973.
-
(1973)
Diabetologia
, vol.9
, pp. 294-298
-
-
Coleman, D.L.1
-
6
-
-
0034703229
-
Role of brain insulin receptor in control of body weight and reproduction
-
Bruning JC, Gautam D, Burks DJ, Schubert M, Orban PC, Klein R, Krone W, Muller-Wieland D, Kahn CR. Role of brain insulin receptor in control of body weight and reproduction. Science 289:2122-2125, 2000.
-
(2000)
Science
, vol.289
, pp. 2122-2125
-
-
Bruning, J.C.1
Gautam, D.2
Burks, D.J.3
Schubert, M.4
Orban, P.C.5
Klein, R.6
Krone, W.7
Muller-Wieland, D.8
Kahn, C.R.9
-
7
-
-
0029946644
-
Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
-
Erickson JC, Clegg KE, Palmiter RD. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 381:415-418, 1996.
-
(1996)
Nature
, vol.381
, pp. 415-418
-
-
Erickson, J.C.1
Clegg, K.E.2
Palmiter, R.D.3
-
8
-
-
0034674684
-
Behavioral characterization of neuropeptide Y knockout mice
-
Bannon AW, Seda J, Carmouche M, Francis JM, Norman MH, Karbon B, McCaleb ML. Behavioral characterization of neuropeptide Y knockout mice. Brain Res 868:79-87, 2000.
-
(2000)
Brain Res
, vol.868
, pp. 79-87
-
-
Bannon, A.W.1
Seda, J.2
Carmouche, M.3
Francis, J.M.4
Norman, M.H.5
Karbon, B.6
McCaleb, M.L.7
-
9
-
-
0029706921
-
The melanocortin receptors: Agonists, antagonists, and the hormonal control of pigmentation
-
Cone RD, Lu D, Koppula S, Vage D, Klungland H, Boston B, Chen W, Orth DN, Pouton C, Kesterson RA. The melanocortin receptors: agonists, antagonists, and the hormonal control of pigmentation. Rec Prog Horm Res 5:287-318, 1996.
-
(1996)
Rec Prog Horm Res
, vol.5
, pp. 287-318
-
-
Cone, R.D.1
Lu, D.2
Koppula, S.3
Vage, D.4
Klungland, H.5
Boston, B.6
Chen, W.7
Orth, D.N.8
Pouton, C.9
Kesterson, R.A.10
-
10
-
-
0030614331
-
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
-
Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385:165-168, 1997.
-
(1997)
Nature
, vol.385
, pp. 165-168
-
-
Fan, W.1
Boston, B.A.2
Kesterson, R.A.3
Hruby, V.J.4
Cone, R.D.5
-
11
-
-
0030775971
-
Leptin increases hypothalamic proopiomelanocortin (POMC) mRNA expression in the rostral arcuate nucleus
-
Schwartz MW, Seeley RJ, Woods SC, Weigle DS, Campfield LA, Burn P, Baskin DG. Leptin increases hypothalamic proopiomelanocortin (POMC) mRNA expression in the rostral arcuate nucleus. Diabetes 46:2119-2123, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 2119-2123
-
-
Schwartz, M.W.1
Seeley, R.J.2
Woods, S.C.3
Weigle, D.S.4
Campfield, L.A.5
Burn, P.6
Baskin, D.G.7
-
12
-
-
0030928715
-
Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus
-
Cheung CC, Clifton DK, Steinier RA. Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus. Endocrinology 138:4489-4492, 1997.
-
(1997)
Endocrinology
, vol.138
, pp. 4489-4492
-
-
Cheung, C.C.1
Clifton, D.K.2
Steinier, R.A.3
-
13
-
-
0026710057
-
Inhibition of hypothalamic neuropeptide Y gene expression by insulin
-
Schwartz MW, Sipols AJ, Marks JL, Sanacora G, White JD, Scheurinck A, Kahn SE, Baskin DG, Woods SC, Figlewicz DP, Porte D Jr. Inhibition of hypothalamic neuropeptide Y gene expression by insulin. Endocrinology 130:3608-1616, 1992.
-
(1992)
Endocrinology
, vol.130
, pp. 3608-1616
-
-
Schwartz, M.W.1
Sipols, A.J.2
Marks, J.L.3
Sanacora, G.4
White, J.D.5
Scheurinck, A.6
Kahn, S.E.7
Baskin, D.G.8
Woods, S.C.9
Figlewicz, D.P.10
Porte D., Jr.11
-
14
-
-
0029739970
-
Identification of targets of leptin action in rat hypothalamus
-
Schwartz MW, Seeley RJ, Campfield LA, Burn P, Baskin DG. Identification of targets of leptin action in rat hypothalamus. J Clin Invest 98:1108-1106, 1996.
-
(1996)
J Clin Invest
, vol.98
, pp. 1108-1106
-
-
Schwartz, M.W.1
Seeley, R.J.2
Campfield, L.A.3
Burn, P.4
Baskin, D.G.5
-
15
-
-
0029098589
-
The role of neuropeptide Y in the antiobesity action of the obese gene product
-
Stephens TW, Bashinski M, Bristow PK, Bue-Vallesky JM, Burgetti SG, Craft L, Prater J, Hoffman J, Huang HM, Kriasticinas A, Mackeltar W, Rostack PR, Schoner B, Smith D, Tinarley FC, Zhang XY, Metman M. The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 377:530-534, 1995.
-
(1995)
Nature
, vol.377
, pp. 530-534
-
-
Stephens, T.W.1
Bashinski, M.2
Bristow, P.K.3
Bue-Vallesky, J.M.4
Burgetti, S.G.5
Craft, L.6
Prater, J.7
Hoffman, J.8
Huang, H.M.9
Kriasticinas, A.10
Mackeltar, W.11
Rostack, P.R.12
Schoner, B.13
Smith, D.14
Tinarley, F.C.15
Zhang, X.Y.16
Metman, M.17
-
16
-
-
13344280346
-
Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice
-
Schwartz MW, Baskin DG, Bukowski TR, Kuijper JL, Foster D, Lasser G, Prunkard DE, Porte D Jr, Woods SC, Seeley RJ, Weigle DS. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 45:531-535, 1996.
-
(1996)
Diabetes
, vol.45
, pp. 531-535
-
-
Schwartz, M.W.1
Baskin, D.G.2
Bukowski, T.R.3
Kuijper, J.L.4
Foster, D.5
Lasser, G.6
Prunkard, D.E.7
Porte D., Jr.8
Woods, S.C.9
Seeley, R.J.10
Weigle, D.S.11
-
17
-
-
0034611732
-
Central nervous system control of food intake
-
Schwartz MW. Central nervous system control of food intake. Nature 404:661-671, 2000.
-
(2000)
Nature
, vol.404
, pp. 661-671
-
-
Schwartz, M.W.1
-
18
-
-
0033559446
-
Role of the CNS melanocortin system in the response to overfeeding
-
Hagan MM, Rushing PA, Schwartz MW, Yagaloff KA, Burn P, Woods SC, Seeley RJ. Role of the CNS melanocortin system in the response to overfeeding. J Neurosci 196:2362-2367, 1999.
-
(1999)
J Neurosci
, vol.196
, pp. 2362-2367
-
-
Hagan, M.M.1
Rushing, P.A.2
Schwartz, M.W.3
Yagaloff, K.A.4
Burn, P.5
Woods, S.C.6
Seeley, R.J.7
-
19
-
-
0030764741
-
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
-
Ollmann MM, Wilson BD, Yang Y, Kerns JA, Chen Y, Gantz I, Barsh GS. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278:135-138, 1997.
-
(1997)
Science
, vol.278
, pp. 135-138
-
-
Ollmann, M.M.1
Wilson, B.D.2
Yang, Y.3
Kerns, J.A.4
Chen, Y.5
Gantz, I.6
Barsh, G.S.7
-
20
-
-
0032130554
-
Coexpression of AgRP and NPY in fasting-activated hypothalamic neurons
-
Hahn TM, Breininger JF, Baskin DG, Schwartz MW. Coexpression of AgRP and NPY in fasting-activated hypothalamic neurons. Nat Neurosci 1:271-272, 1998.
-
(1998)
Nat Neurosci
, vol.1
, pp. 271-272
-
-
Hahn, T.M.1
Breininger, J.F.2
Baskin, D.G.3
Schwartz, M.W.4
-
21
-
-
0034527518
-
Chronic blockade of the melanocortin 4 receptor subtype leads to obesity independently of neuropeptide Y action, with no adverse effects on the gonadotropic and somatotropic axes
-
Raposinho PD, Castillo E, d'Alleves V, Broqua P, Pralong FP, Aubert ML. Chronic blockade of the melanocortin 4 receptor subtype leads to obesity independently of neuropeptide Y action, with no adverse effects on the gonadotropic and somatotropic axes. Endocrinology 141:4419-4427, 2000.
-
(2000)
Endocrinology
, vol.141
, pp. 4419-4427
-
-
Raposinho, P.D.1
Castillo, E.2
D'Alleves, V.3
Broqua, P.4
Pralong, F.P.5
Aubert, M.L.6
-
22
-
-
0032863468
-
Obesity in the mouse model of proopiomelanocortin deficiency responds to peripheral melanocortin
-
Yaswen L, Diehl N, Brennam MB, Hochgeschwender V. Obesity in the mouse model of proopiomelanocortin deficiency responds to peripheral melanocortin. Nat Med 5:1066-1070, 1999.
-
(1999)
Nat Med
, vol.5
, pp. 1066-1070
-
-
Yaswen, L.1
Diehl, N.2
Brennam, M.B.3
Hochgeschwender, V.4
-
23
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88:131-141, 1997.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
Burn, P.13
Lee, F.14
-
25
-
-
0032577309
-
The search for human obesity genes
-
Comuzie AG, Allison DB. The search for human obesity genes. Science 280:1374-1377, 1998.
-
(1998)
Science
, vol.280
, pp. 1374-1377
-
-
Comuzie, A.G.1
Allison, D.B.2
-
26
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman PG. Obesity as a medical problem. Nature 404:635-643, 2000.
-
(2000)
Nature
, vol.404
, pp. 635-643
-
-
Kopelman, P.G.1
|