메뉴 건너뛰기




Volumn 11, Issue , 2011, Pages 169-198

Magnetic resonance spectroscopic methods for the assessment of metabolic functions in the diseased brain

Author keywords

13C 15N; Alzheimer s disease; Brain; Metabolism; Neurodegeneration; Parkinson s disease

Indexed keywords

4 AMINOBUTYRIC ACID; CREATINE; CREATINE PHOSPHATE; GLUCOSE; INOSITOL; LACTIC ACID; LIPID; N ACETYLASPARTIC ACID; PHOSPHORYLCHOLINE; TAURINE; ASPARTIC ACID; ISOTOPE; N-ACETYLASPARTATE; PROTON;

EID: 84872084552     PISSN: 18663370     EISSN: 18663389     Source Type: Book Series    
DOI: 10.1007/7854_2011_166     Document Type: Article
Times cited : (13)

References (155)
  • 1
    • 74149085154 scopus 로고    scopus 로고
    • The epidemiology of dementia associated with Parkinson disease
    • Aarsland D, Kurz MW (2010) The epidemiology of dementia associated with Parkinson disease. J Neurol Sci 289(1-2): 18-22. doi: S0022-510X(09)00819-3[pii]10. 1016/j. jns. 2009. 08. 034
    • (2010) J Neurol Sci , vol.289 , Issue.1 , pp. 18-22
    • Aarsland, D.1    Kurz, M.W.2
  • 2
    • 20444435798 scopus 로고    scopus 로고
    • Hippocampal metabolic abnormalities in mild cognitive impairment and Alzheimer's disease
    • Ackl N, Ising M, Schreiber YA, Atiya M, Sonntag A, Auer DP (2005) Hippocampal metabolic abnormalities in mild cognitive impairment and Alzheimer's disease. Neurosci Lett 384(1-2): 23-28. doi: 10. 1016/j. neulet. 2005. 04. 035
    • (2005) Neurosci Lett , vol.384 , Issue.2 , pp. 23-28
    • Ackl, N.1    Ising, M.2    Schreiber, Y.A.3    Atiya, M.4    Sonntag, A.5    Auer, D.P.6
  • 3
    • 77955190917 scopus 로고    scopus 로고
    • Current therapies and new strategies for the management of Alzheimer's disease
    • Aderinwale OG, Ernst HW, Mousa SA (2010) Current therapies and new strategies for the management of Alzheimer's disease. Am J Alzheimers Dis Other Demen 25(5): 414-424. doi: 10. 1177/1533317510372372
    • (2010) Am J Alzheimers Dis Other Demen , vol.25 , Issue.5 , pp. 414-424
    • Aderinwale, O.G.1    Ernst, H.W.2    Mousa, S.A.3
  • 5
    • 0021257757 scopus 로고
    • Changes of biogenic amines and their metabolites in postmortem brains from patients with Alzheimer-type dementia
    • Arai H, Kosaka K, Iizuka R (1984) Changes of biogenic amines and their metabolites in postmortem brains from patients with Alzheimer-type dementia. J Neurochem 43: 388-393
    • (1984) J Neurochem , vol.43 , pp. 388-393
    • Arai, H.1    Kosaka, K.2    Iizuka, R.3
  • 7
    • 46849088379 scopus 로고    scopus 로고
    • Proton spectroscopy in Alzheimer's disease and cognitive impairment no dementia: a communitybased study
    • Azevedo D, Tatsch M, Hototian SR, Bazzarella MC, Castro CC, Bottino CM (2008) Proton spectroscopy in Alzheimer's disease and cognitive impairment no dementia: a communitybased study. Dement Geriatr Cogn Disord 25(6): 491-500. doi: 10. 1159/000128275
    • (2008) Dement Geriatr Cogn Disord , vol.25 , Issue.6 , pp. 491-500
    • Azevedo, D.1    Tatsch, M.2    Hototian, S.R.3    Bazzarella, M.C.4    Castro, C.C.5    Bottino, C.M.6
  • 8
    • 0032802545 scopus 로고    scopus 로고
    • Factors affecting the quantification of short echo in vivo 1H MR spectra: prior knowledge, peak elimination, and filtering
    • Bartha R, Drost DJ, Williamson PC (1999) Factors affecting the quantification of short echo in vivo 1H MR spectra: prior knowledge, peak elimination, and filtering. NMR Biomed 12(4): 205-216
    • (1999) NMR Biomed , vol.12 , Issue.4 , pp. 205-216
    • Bartha, R.1    Drost, D.J.2    Williamson, P.C.3
  • 9
    • 0037409849 scopus 로고    scopus 로고
    • N-acetylaspartate in the vertebrate brain: metabolism and function
    • Baslow MH (2003) N-acetylaspartate in the vertebrate brain: metabolism and function. Neurochem Res 28(6): 941-953
    • (2003) Neurochem Res , vol.28 , Issue.6 , pp. 941-953
    • Baslow, M.H.1
  • 10
    • 0025923743 scopus 로고
    • 13C NMR for the assessment of human brain glucose metabolism in vivo
    • Beckmann N, Turkalj I, Seelig J, Keller U (1991) 13C NMR for the assessment of human brain glucose metabolism in vivo. Biochem 30(26): 6362-6366
    • (1991) Biochem , vol.30 , Issue.26 , pp. 6362-6366
    • Beckmann, N.1    Turkalj, I.2    Seelig, J.3    Keller, U.4
  • 11
    • 0033798938 scopus 로고    scopus 로고
    • The role of magnetic resonance imaging and spectroscopy in transplantation: from animal models to man
    • Beckmann N, Hof RP, Rudin M (2000) The role of magnetic resonance imaging and spectroscopy in transplantation: from animal models to man. NMR Biomed 13(6): 329-348. doi: 10. 1002/1099-1492(200010)13: 6\329: AID-NBM653[3. 0. CO; 2-W[pii]
    • (2000) NMR Biomed , vol.13 , Issue.6 , pp. 329-348
    • Beckmann, N.1    Hof, R.P.2    Rudin, M.3
  • 12
    • 35748954370 scopus 로고    scopus 로고
    • GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations
    • Ben-Ari Y, Gaiarsa JL, Tyzio R, Khazipov R (2007) GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations. Physiol Rev 87(4): 1215-1284. doi: 87/4/1215[pii]10. 1152/physrev. 00017. 2006
    • (2007) Physiol Rev , vol.87 , Issue.4 , pp. 1215-1284
    • Ben-Ari, Y.1    Gaiarsa, J.L.2    Tyzio, R.3    Khazipov, R.4
  • 13
    • 0019872434 scopus 로고
    • Selective loss of neurones of origin of adrenergic projection to cerebral cortex (nucleus locus coeruleus) in senile dementia
    • Bondareff W, Mountjoy CQ, Roth M (1981) Selective loss of neurones of origin of adrenergic projection to cerebral cortex (nucleus locus coeruleus) in senile dementia. Lancet 1: 783-784
    • (1981) Lancet , vol.1 , pp. 783-784
    • Bondareff, W.1    Mountjoy, C.Q.2    Roth, M.3
  • 14
    • 7944233769 scopus 로고    scopus 로고
    • Cognitive dysfunction and dementia in Parkinson's disease
    • Bosboom JL, Stoffers D, Wolters E (2004) Cognitive dysfunction and dementia in Parkinson's disease. J Neural Transm 111(10-11): 1303-1315. doi: 10. 1007/s00702-004-0168-1
    • (2004) J Neural Transm , vol.111 , Issue.10 , pp. 1303-1315
    • Bosboom, J.L.1    Stoffers, D.2    Wolters, E.3
  • 15
    • 64949132814 scopus 로고    scopus 로고
    • Absolute metabolite concentrations calibrated using the total water signal in brain (1) H MRS
    • Brief EE, Moll R, Li DK, Mackay AL (2009) Absolute metabolite concentrations calibrated using the total water signal in brain (1) H MRS. NMRBiomed 22(3): 349-354. doi: 10. 1002/nbm. 1349
    • (2009) NMRBiomed , vol.22 , Issue.3 , pp. 349-354
    • Brief, E.E.1    Moll, R.2    Li, D.K.3    Mackay, A.L.4
  • 16
    • 0038727935 scopus 로고    scopus 로고
    • PET studies on the function of dopamine in health and Parkinson's disease
    • Brooks DJ (2003) PET studies on the function of dopamine in health and Parkinson's disease. Ann N Y Acad Sci 991: 22-35
    • (2003) Ann N Y Acad Sci , vol.991 , pp. 22-35
    • Brooks, D.J.1
  • 19
    • 1542328813 scopus 로고    scopus 로고
    • Similar 1H magnetic resonance spectroscopic metabolic pattern in the medial temporal lobes of patients with mild cognitive impairment and Alzheimer disease
    • Chantal S, Braun CM, Bouchard RW, Labelle M, Boulanger Y (2004) Similar 1H magnetic resonance spectroscopic metabolic pattern in the medial temporal lobes of patients with mild cognitive impairment and Alzheimer disease. Brain Res 1003(1-2): 26-35. doi: 10. 1016/j. brainres. 2003. 11. 074
    • (2004) Brain Res , vol.1003 , Issue.2 , pp. 26-35
    • Chantal, S.1    Braun, C.M.2    Bouchard, R.W.3    Labelle, M.4    Boulanger, Y.5
  • 20
    • 62649084065 scopus 로고    scopus 로고
    • Multimodal neuroimaging provides a highly consistent picture of energy metabolism, validating 31P MRS for measuring brain ATP synthesis
    • Chaumeil MM, Valette J, Guillermier M, Brouillet E, Boumezbeur F, Herard AS, Bloch G, Hantraye P, Lebon V (2009) Multimodal neuroimaging provides a highly consistent picture of energy metabolism, validating 31P MRS for measuring brain ATP synthesis. Proc Nat Acad Sci U S A 106 (10): 3988-3993. doi: 10. 1073/pnas. 0806516106
    • (2009) Proc Nat Acad Sci U S A , vol.106 , Issue.10 , pp. 3988-3993
    • Chaumeil, M.M.1    Valette, J.2    Guillermier, M.3    Brouillet, E.4    Boumezbeur, F.5    Herard, A.S.6    Bloch, G.7    Hantraye, P.8    Lebon, V.9
  • 21
    • 0032471783 scopus 로고    scopus 로고
    • Neuronal laterality in Parkinson's disease with unilateral symptom by in vivo 1H magnetic resonance spectroscopy
    • Choe BY, Park JW, Lee KS, Son BC, Kim MC, Kim BS, Suh TS, Lee HK, Shinn KS (1998) Neuronal laterality in Parkinson's disease with unilateral symptom by in vivo 1H magnetic resonance spectroscopy. Invest Radiol 33(8): 450-455
    • (1998) Invest Radiol , vol.33 , Issue.8 , pp. 450-455
    • Choe, B.Y.1    Park, J.W.2    Lee, K.S.3    Son, B.C.4    Kim, M.C.5    Kim, B.S.6    Suh, T.S.7    Lee, H.K.8    Shinn, K.S.9
  • 22
    • 0344850193 scopus 로고    scopus 로고
    • Noninvasive measurements of [1-(13)C]glycogen concentrations and metabolism in rat brain in vivo
    • Choi IY, Tkac I, Ugurbil K, Gruetter R (1999) Noninvasive measurements of [1-(13)C]glycogen concentrations and metabolism in rat brain in vivo. J Neurochem 73(3): 1300-1308
    • (1999) J Neurochem , vol.73 , Issue.3 , pp. 1300-1308
    • Choi, I.Y.1    Tkac, I.2    Ugurbil, K.3    Gruetter, R.4
  • 23
    • 34249704131 scopus 로고    scopus 로고
    • Application of MRS to mouse models of neurodegenerative illness
    • Choi JK, Dedeoglu A, Jenkins BG (2007) Application of MRS to mouse models of neurodegenerative illness. NMR Biomed 20(3): 216-237. doi: 10. 1002/nbm. 1145
    • (2007) NMR Biomed , vol.20 , Issue.3 , pp. 216-237
    • Choi, J.K.1    Dedeoglu, A.2    Jenkins, B.G.3
  • 24
    • 0031731910 scopus 로고    scopus 로고
    • N-acetyl aspartate: a marker for neuronal loss or mitochondrial dysfunction
    • Clark JB (1998) N-acetyl aspartate: a marker for neuronal loss or mitochondrial dysfunction. Dev Neurosci 20(4-5): 271-276. doi: dne20271[pii]
    • (1998) Dev Neurosci , vol.20 , Issue.5 , pp. 271-276
    • Clark, J.B.1
  • 25
    • 0034477117 scopus 로고    scopus 로고
    • Basal ganglia metabolite concentrations in idiopathic Parkinson's disease and multiple system atrophy measured by proton magnetic resonance spectroscopy
    • Clarke CE, Lowry M (2000) Basal ganglia metabolite concentrations in idiopathic Parkinson's disease and multiple system atrophy measured by proton magnetic resonance spectroscopy. Eur J Neurol 7(6): 661-665. doi: ene111[pii]
    • (2000) Eur J Neurol , vol.7 , Issue.6 , pp. 661-665
    • Clarke, C.E.1    Lowry, M.2
  • 26
    • 0035554364 scopus 로고    scopus 로고
    • Systematic review of proton magnetic resonance spectroscopy of the striatum in parkinsonian syndromes
    • Clarke CE, Lowry M (2001) Systematic review of proton magnetic resonance spectroscopy of the striatum in parkinsonian syndromes. Eur J Neurol Soc 8(6): 573-577
    • (2001) Eur J Neurol Soc , vol.8 , Issue.6 , pp. 573-577
    • Clarke, C.E.1    Lowry, M.2
  • 28
    • 33748577363 scopus 로고    scopus 로고
    • Selective neuronal degeneration in Huntington's disease
    • Cowan CM, Raymond LA (2006) Selective neuronal degeneration in Huntington's disease. Curr Top Dev Biol 75: 25-71. doi: S0070-2153(06)75002-5[pii]10. 1016/S0070-2153(06)75002-5
    • (2006) Curr Top Dev Biol , vol.75 , pp. 25-71
    • Cowan, C.M.1    Raymond, L.A.2
  • 29
    • 0030440081 scopus 로고    scopus 로고
    • Development and applications of in vivo clinical magnetic resonance spectroscopy
    • Cox IJ (1996) Development and applications of in vivo clinical magnetic resonance spectroscopy. Prog Biophys Mol Biol 65(1-2): 45-81. doi: S0079-6107(96)00006-5[pii]
    • (1996) Prog Biophys Mol Biol , vol.65 , Issue.2 , pp. 45-81
    • Cox, I.J.1
  • 33
    • 0025127226 scopus 로고
    • Improved quantification of in vivo 1H NMR spectra by optimization of signal acquisition and processing and by incorporation of prior knowledge into the spectral fitting
    • de Graaf AA, Bovee WM (1990) Improved quantification of in vivo 1H NMR spectra by optimization of signal acquisition and processing and by incorporation of prior knowledge into the spectral fitting. Magn Reson Med 15(2): 305-319
    • (1990) Magn Reson Med , vol.15 , Issue.2 , pp. 305-319
    • de Graaf, A.A.1    Bovee, W.M.2
  • 34
    • 0348149164 scopus 로고    scopus 로고
    • In vivo 1H-[13C]-NMR spectroscopy of cerebral metabolism
    • de Graaf RA, Mason GF, Patel AB, Behar KL, Rothman DL (2003) In vivo 1H-[13C]-NMR spectroscopy of cerebral metabolism. NMR Biomed 16(6-7): 339-357. doi: 10. 1002/nbm. 847
    • (2003) NMR Biomed , vol.16 , Issue.7 , pp. 339-357
    • de Graaf, R.A.1    Mason, G.F.2    Patel, A.B.3    Behar, K.L.4    Rothman, D.L.5
  • 36
    • 0036787479 scopus 로고    scopus 로고
    • Longitudinal quantitative proton magnetic resonance spectroscopy of the hippocampus in Alzheimer's disease
    • Dixon RM, Bradley KM, Budge MM, Styles P, Smith AD (2002) Longitudinal quantitative proton magnetic resonance spectroscopy of the hippocampus in Alzheimer's disease. Brain J Neurol 125(Pt 10): 2332-2341
    • (2002) Brain J Neurol , vol.125 , pp. 2332-2341
    • Dixon, R.M.1    Bradley, K.M.2    Budge, M.M.3    Styles, P.4    Smith, A.D.5
  • 37
    • 0032556505 scopus 로고    scopus 로고
    • Prediction of cognitive decline in early Alzheimer's disease
    • Doraiswamy PM, Charles HC, Krishnan KR (1998) Prediction of cognitive decline in early Alzheimer's disease. Lancet 352(9141): 1678. doi: 10. 1016/S0140-6736(05)61449-3
    • (1998) Lancet , vol.352 , Issue.9141 , pp. 1678
    • Doraiswamy, P.M.1    Charles, H.C.2    Krishnan, K.R.3
  • 38
    • 33846088914 scopus 로고    scopus 로고
    • Efficient in vivo 31P magnetization transfer approach for noninvasively determining multiple kinetic parameters and metabolic fluxes of ATPmetabolism in the human brain
    • Du F, Zhu XH, Qiao H, Zhang X, Chen W (2007) Efficient in vivo 31P magnetization transfer approach for noninvasively determining multiple kinetic parameters and metabolic fluxes of ATPmetabolism in the human brain. Magn Reson Med57(1): 103-114. doi: 10. 1002/mrm. 21107
    • (2007) Magn Reson Med , vol.57 , Issue.1 , pp. 103-114
    • Du, F.1    Zhu, X.H.2    Qiao, H.3    Zhang, X.4    Chen, W.5
  • 40
    • 0030840579 scopus 로고    scopus 로고
    • Changes in putamen N-acetylaspartate and choline ratios in untreated and levodopa-treated Parkinson's disease: a proton magnetic resonance spectroscopy study
    • Ellis CM, Lemmens G, Williams SC, Simmons A, Dawson J, Leigh PN, Chaudhuri KR (1997) Changes in putamen N-acetylaspartate and choline ratios in untreated and levodopa-treated Parkinson's disease: a proton magnetic resonance spectroscopy study. Neurology 49(2): 438-444
    • (1997) Neurology , vol.49 , Issue.2 , pp. 438-444
    • Ellis, C.M.1    Lemmens, G.2    Williams, S.C.3    Simmons, A.4    Dawson, J.5    Leigh, P.N.6    Chaudhuri, K.R.7
  • 41
    • 42449147949 scopus 로고    scopus 로고
    • A modern hypothesis: The distinct pathologies of dementia associated with Parkinson's disease versus Alzheimer's disease
    • Farlow MR, Cummings J (2008) A modern hypothesis: The distinct pathologies of dementia associated with Parkinson's disease versus Alzheimer's disease. Dement Geriatr Cogn Disord 25(4): 301-308. doi: 10. 1159/000119104
    • (2008) Dement Geriatr Cogn Disord , vol.25 , Issue.4 , pp. 301-308
    • Farlow, M.R.1    Cummings, J.2
  • 42
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: substantia nigra regional selectivity
    • Fearnley JM, Lees AJ (1991) Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain J Neurol 114(Pt 5): 2283-2301
    • (1991) Brain J Neurol , vol.114 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 43
    • 0036979072 scopus 로고    scopus 로고
    • A comprehensive review of proton magnetic resonance spectroscopy studies in dementia and Parkinson's disease
    • Firbank MJ, Harrison RM, O'Brien JT (2002) A comprehensive review of proton magnetic resonance spectroscopy studies in dementia and Parkinson's disease. Dement Geriatr Cogn Disord 14(2): 64-76
    • (2002) Dement Geriatr Cogn Disord , vol.14 , Issue.2 , pp. 64-76
    • Firbank, M.J.1    Harrison, R.M.2    O'Brien, J.T.3
  • 44
    • 0016823810 scopus 로고
    • Mini-mental state. A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR (1975) Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12(3): 189-198
    • (1975) J Psychiatr Res , vol.12 , Issue.3 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 45
    • 0021330769 scopus 로고
    • Glutamate: a neurotransmitter in mammalian brain
    • Fonnum F (1984) Glutamate: a neurotransmitter in mammalian brain. J Neurochem 42(1): 1-11
    • (1984) J Neurochem , vol.42 , Issue.1 , pp. 1-11
    • Fonnum, F.1
  • 48
    • 0011799357 scopus 로고    scopus 로고
    • In vivo molecular imaging: ligand development and research applications
    • Davis KL, Charney D, Coyle JT, Nemeroff C (eds), Lippincott Williams & Wilkins, Philadelphia
    • Fumita M, Innis RB (2002) In vivo molecular imaging: ligand development and research applications. In: Davis KL, Charney D, Coyle JT, Nemeroff C (eds) Neuropsychopharmacology-the fifth generation of progress. Lippincott Williams & Wilkins, Philadelphia
    • (2002) Neuropsychopharmacology-the fifth generation of progress
    • Fumita, M.1    Innis, R.B.2
  • 49
    • 41849121889 scopus 로고    scopus 로고
    • Therapeutic target metabolism observed using hyperpolarized 15N choline
    • Gabellieri C, Reynolds S, Lavie A, Payne GS, Leach MO, Eykyn TR (2008) Therapeutic target metabolism observed using hyperpolarized 15N choline. J Am Chem Soc 130(14): 4598-4599. doi: 10. 1021/ja8001293
    • (2008) J Am Chem Soc , vol.130 , Issue.14 , pp. 4598-4599
    • Gabellieri, C.1    Reynolds, S.2    Lavie, A.3    Payne, G.S.4    Leach, M.O.5    Eykyn, T.R.6
  • 56
    • 33746625531 scopus 로고    scopus 로고
    • Real-time metabolic imaging
    • Golman K, in'tZandt R, Thaning M (2006a) Real-time metabolic imaging. Proc Natl Acad Sci U S A 103(30): 11270-11275. doi: 0601319103[pii]10. 1073/pnas. 0601319103
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.30 , pp. 11270-11275
    • Golman, K.1    in'tZandt, R.2    Thaning, M.3
  • 57
    • 33845292936 scopus 로고    scopus 로고
    • Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis
    • Golman K, Zandt RI, Lerche M, Pehrson R, Ardenkjaer-Larsen JH (2006b) Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis. Cancer Res 66(22): 10855-10860. doi: 66/22/10855[pii]10. 1158/0008-5472. CAN-06-2564
    • (2006) Cancer Res , vol.66 , Issue.22 , pp. 10855-10860
    • Golman, K.1    Zandt, R.I.2    Lerche, M.3    Pehrson, R.4    Ardenkjaer-Larsen, J.H.5
  • 59
    • 55549124222 scopus 로고    scopus 로고
    • Brain metabolism differs in Alzheimer's disease and Parkinson's disease dementia
    • Griffith HR, den Hollander JA, Okonkwo OC, O'Brien T, Watts RL, Marson DC (2008) Brain metabolism differs in Alzheimer's disease and Parkinson's disease dementia. Alzheimers Dement 4(6): 421-427. doi: S1552-5260(08)00128-3[pii]10. 1016/j. jalz. 2008. 04. 008
    • (2008) Alzheimers Dement , vol.4 , Issue.6 , pp. 421-427
    • Griffith, H.R.1    den Hollander, J.A.2    Okonkwo, O.C.3    O'Brien, T.4    Watts, R.L.5    Marson, D.C.6
  • 60
    • 66249134238 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy in dementias and mild cognitive impairment
    • Griffith HR, Stewart CC, den Hollander JA (2009) Proton magnetic resonance spectroscopy in dementias and mild cognitive impairment. Int Rev Neurobiol 84: 105-131. doi: S0074-7742(09) 00406-1[pii]10. 1016/S0074-7742(09)00406-1
    • (2009) Int Rev Neurobiol , vol.84 , pp. 105-131
    • Griffith, H.R.1    Stewart, C.C.2    den Hollander, J.A.3
  • 61
    • 0037311513 scopus 로고    scopus 로고
    • High-resolution 3D proton spectroscopic imaging of the human brain at 3 T: SNR issues and application for anatomy-matched voxel sizes
    • Gruber S, Mlynarik V, Moser E (2003) High-resolution 3D proton spectroscopic imaging of the human brain at 3 T: SNR issues and application for anatomy-matched voxel sizes. Magn Reson Med 49: 299-306
    • (2003) Magn Reson Med , vol.49 , pp. 299-306
    • Gruber, S.1    Mlynarik, V.2    Moser, E.3
  • 64
    • 33748901821 scopus 로고    scopus 로고
    • Chronic highfrequency stimulation of the subthalamic nucleus and L-DOPA treatment in experimental parkinsonism: effects on motor behaviour and striatal glutamate transmission
    • Gubellini P, Eusebio A, Oueslati A, Melon C, Kerkerian-Le Goff L, Salin P (2006) Chronic highfrequency stimulation of the subthalamic nucleus and L-DOPA treatment in experimental parkinsonism: effects on motor behaviour and striatal glutamate transmission. Eur J Neurosci 24(6): 1802-1814. doi: EJN5047[pii]10. 1111/j. 1460-9568. 2006. 05047. x
    • (2006) Eur J Neurosci , vol.24 , Issue.6 , pp. 1802-1814
    • Gubellini, P.1    Eusebio, A.2    Oueslati, A.3    Melon, C.4    Kerkerian-Le Goff, L.5    Salin, P.6
  • 65
    • 78651227735 scopus 로고    scopus 로고
    • Kinetics from indirectly detected hyperpolarized NMR spectroscopy by using spatially selective coherence transfers
    • Harris T, Giraudeau P, Frydman L (2010) Kinetics from indirectly detected hyperpolarized NMR spectroscopy by using spatially selective coherence transfers. Chemistry. doi: 10. 1002/chem. 201002151
    • (2010) Chemistry
    • Harris, T.1    Giraudeau, P.2    Frydman, L.3
  • 66
    • 72649106290 scopus 로고    scopus 로고
    • Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease
    • Hattingen E, Magerkurth J, Pilatus U, Mozer A, Seifried C, Steinmetz H, Zanella F, Hilker R (2009) Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease. Brain 132(Pt 12): 3285-3297. doi: awp293[pii]10. 1093/brain/awp293
    • (2009) Brain , vol.132 , pp. 3285-3297
    • Hattingen, E.1    Magerkurth, J.2    Pilatus, U.3    Mozer, A.4    Seifried, C.5    Steinmetz, H.6    Zanella, F.7    Hilker, R.8
  • 67
    • 57749101148 scopus 로고    scopus 로고
    • Multinuclear magnetic resonance spectroscopy for in vivo assessment of mitochondrial dysfunction in Parkinson's disease
    • Henchcliffe C, Shungu DC, Mao X, Huang C, Nirenberg MJ, Jenkins BG, Beal MF (2008) Multinuclear magnetic resonance spectroscopy for in vivo assessment of mitochondrial dysfunction in Parkinson's disease. Ann N Y Acad Sci 1147: 206-220. doi: NYAS1147037[-pii]10. 1196/annals. 1427. 037
    • (2008) Ann N Y Acad Sci , vol.1147 , pp. 206-220
    • Henchcliffe, C.1    Shungu, D.C.2    Mao, X.3    Huang, C.4    Nirenberg, M.J.5    Jenkins, B.G.6    Beal, M.F.7
  • 68
    • 43549110738 scopus 로고    scopus 로고
    • Positron emission tomography imaging in dementia
    • Herholz K, Carter SF, Jones M (2007) Positron emission tomography imaging in dementia. Br J Radiol 80 Spec No 2: S160-167. doi: 80/Special_Issue_2/S160 [pii] 10. 1259/bjr/97295129
    • (2007) Br J Radiol 80 Spec No , vol.2 , pp. S160-S167
    • Herholz, K.1    Carter, S.F.2    Jones, M.3
  • 69
    • 0036771737 scopus 로고    scopus 로고
    • 1H and 31P spectroscopy and bioenergetics in the lateralization of seizures in temporal lobe epilepsy
    • Hetherington HP, Pan JW, Spencer DD (2002) 1H and 31P spectroscopy and bioenergetics in the lateralization of seizures in temporal lobe epilepsy. J Magn Reson Imaging 16(4): 477-483. doi: 10. 1002/jmri. 10177
    • (2002) J Magn Reson Imaging , vol.16 , Issue.4 , pp. 477-483
    • Hetherington, H.P.1    Pan, J.W.2    Spencer, D.D.3
  • 70
    • 0023740954 scopus 로고
    • Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease
    • Hirsch E, Graybiel AM, Agid YA (1988) Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature 334(6180): 345-348. doi: 10. 1038/334345a0
    • (1988) Nature , vol.334 , Issue.6180 , pp. 345-348
    • Hirsch, E.1    Graybiel, A.M.2    Agid, Y.A.3
  • 73
    • 0036116239 scopus 로고    scopus 로고
    • How can we measure substrate, metabolite and neurotransmitter concentrations in the human brain?
    • Hutchinson PJ, O'Connell MT, Kirkpatrick PJ, Pickard JD (2002) How can we measure substrate, metabolite and neurotransmitter concentrations in the human brain? Physiol Meas 23(2): R75-109
    • (2002) Physiol Meas , vol.23 , Issue.2 , pp. R75-109
    • Hutchinson, P.J.1    O'Connell, M.T.2    Kirkpatrick, P.J.3    Pickard, J.D.4
  • 74
    • 84934435185 scopus 로고    scopus 로고
    • Dynamic imaging of brain function
    • Hyder F (2009) Dynamic imaging of brain function. Methods Mol Biol 489: 3-21. doi: 10. 1007/978-1-59745-543-5_1
    • (2009) Methods Mol Biol , vol.489 , pp. 3-21
    • Hyder, F.1
  • 76
    • 23944432134 scopus 로고    scopus 로고
    • A comparative study of the different N-acetylaspartate measures of the medial temporal lobe in Alzheimer's disease
    • Jessen F, Traeber F, Freymann N, Maier W, Schild H, Heun R, Block W (2005) A comparative study of the different N-acetylaspartate measures of the medial temporal lobe in Alzheimer's disease. Dement Geriatr Cogn Disord 20(2-3): 178-183
    • (2005) Dement Geriatr Cogn Disord , vol.20 , Issue.3 , pp. 178-183
    • Jessen, F.1    Traeber, F.2    Freymann, N.3    Maier, W.4    Schild, H.5    Heun, R.6    Block, W.7
  • 77
    • 33747038088 scopus 로고    scopus 로고
    • Treatment monitoring and response prediction with proton MR spectroscopy in AD
    • Jessen F, Traeber F, Freymann K, Maier W, Schild HH, Block W (2006) Treatment monitoring and response prediction with proton MR spectroscopy in AD. Neurology 67(3): 528-530. doi: 10. 1212/01. wnl. 0000228218. 68451. 31
    • (2006) Neurology , vol.67 , Issue.3 , pp. 528-530
    • Jessen, F.1    Traeber, F.2    Freymann, K.3    Maier, W.4    Schild, H.H.5    Block, W.6
  • 81
    • 20444382748 scopus 로고    scopus 로고
    • Direct detection of brain acetylcholine synthesis by magnetic resonance spectroscopy
    • Katz-Brull R, Koudinov AR, Degani H (2005) Direct detection of brain acetylcholine synthesis by magnetic resonance spectroscopy. Brain Res 1048(1-2): 202-210. doi: S0006-8993(05)00684-0[pii]10. 1016/j. brainres. 2005. 04. 080
    • (2005) Brain Res , vol.1048 , Issue.2 , pp. 202-210
    • Katz-Brull, R.1    Koudinov, A.R.2    Degani, H.3
  • 82
    • 0028129578 scopus 로고
    • Nuclear magnetic resonance spectroscopy studies of the brain
    • Kauppinen RA, Williams SR (1994) Nuclear magnetic resonance spectroscopy studies of the brain. Prog Neurobiol 44(1): 87-118. doi: 0301-0082(94)90058-2[pii]
    • (1994) Prog Neurobiol , vol.44 , Issue.1 , pp. 87-118
    • Kauppinen, R.A.1    Williams, S.R.2
  • 86
    • 57149097868 scopus 로고    scopus 로고
    • Efficient 1H to 31P polarization transfer on a clinical 3T MR system
    • Klomp DW, Wijnen JP, Scheenen TW, Heerschap A (2008) Efficient 1H to 31P polarization transfer on a clinical 3T MR system. Magn Reson Med 60(6): 1298-1305. doi: 10. 1002/mrm. 21733
    • (2008) Magn Reson Med , vol.60 , Issue.6 , pp. 1298-1305
    • Klomp, D.W.1    Wijnen, J.P.2    Scheenen, T.W.3    Heerschap, A.4
  • 87
    • 0009364134 scopus 로고
    • Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease
    • Kosik KS, Joachim CL, Selkoe DJ (1986) Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease. Proc Nat Acad Sci U S A 83(11): 4044-4048
    • (1986) Proc Nat Acad Sci U S A , vol.83 , Issue.11 , pp. 4044-4048
    • Kosik, K.S.1    Joachim, C.L.2    Selkoe, D.J.3
  • 89
    • 1842830710 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of the effects of donepezil on neuronal markers and hippocampal volumes in Alzheimer's disease
    • Krishnan KR, Charles HC, Doraiswamy PM, Mintzer J, Weisler R, Yu X, Perdomo C, Ieni JR, Rogers S (2003) Randomized, placebo-controlled trial of the effects of donepezil on neuronal markers and hippocampal volumes in Alzheimer's disease. Am J Psychiatry 160(11): 2003-2011
    • (2003) Am J Psychiatry , vol.160 , Issue.11 , pp. 2003-2011
    • Krishnan, K.R.1    Charles, H.C.2    Doraiswamy, P.M.3    Mintzer, J.4    Weisler, R.5    Yu, X.6    Perdomo, C.7    Ieni, J.R.8    Rogers, S.9
  • 90
    • 78649988282 scopus 로고    scopus 로고
    • Neurochemical profile of the developing mouse cortex determined by in vivo 1H NMR spectroscopy at 14. 1 T and the effect of recurrent anaesthesia
    • Kulak A, Duarte JM, Do KQ, Gruetter R (2010) Neurochemical profile of the developing mouse cortex determined by in vivo 1H NMR spectroscopy at 14. 1 T and the effect of recurrent anaesthesia. J Neurochem 115(6): 1466-1477. doi: 10. 1111/j. 1471-4159. 2010. 07051. x
    • (2010) J Neurochem , vol.115 , Issue.6 , pp. 1466-1477
    • Kulak, A.1    Duarte, J.M.2    Do, K.Q.3    Gruetter, R.4
  • 91
    • 77955103840 scopus 로고    scopus 로고
    • Neurochemical profile of the mouse hypothalamus using in vivo 1H MRS at 14. 1 T
    • Lei H, Poitry-Yamate C, Preitner F, Thorens B, Gruetter R (2010) Neurochemical profile of the mouse hypothalamus using in vivo 1H MRS at 14. 1 T. NMR Biomed 23(6): 578-583. doi: 10. 1002/nbm. 1498
    • (2010) NMR Biomed , vol.23 , Issue.6 , pp. 578-583
    • Lei, H.1    Poitry-Yamate, C.2    Preitner, F.3    Thorens, B.4    Gruetter, R.5
  • 92
    • 0025367229 scopus 로고
    • Effects of hypernatremia on organic brain osmoles
    • Lien YH, Shapiro JI, Chan L (1990) Effects of hypernatremia on organic brain osmoles. J Clin Invest 85(5): 1427-1435. doi: 10. 1172/JCI114587
    • (1990) J Clin Invest , vol.85 , Issue.5 , pp. 1427-1435
    • Lien, Y.H.1    Shapiro, J.I.2    Chan, L.3
  • 93
    • 16344364888 scopus 로고    scopus 로고
    • Efficacy of proton magnetic resonance spectroscopy in neurological diagnosis and neurotherapeutic decision making
    • Lin A, Ross BD, Harris K, Wong W (2005) Efficacy of proton magnetic resonance spectroscopy in neurological diagnosis and neurotherapeutic decision making. NeuroRx 2(2): 197-214
    • (2005) NeuroRx , vol.2 , Issue.2 , pp. 197-214
    • Lin, A.1    Ross, B.D.2    Harris, K.3    Wong, W.4
  • 95
    • 0030051604 scopus 로고    scopus 로고
    • Alzheimer disease and subcortical ischemic vascular dementia: evaluation by combining MR imaging segmentation and H-1 MR spectroscopic imaging
    • MacKay S, Ezekiel F, Di Sclafani V, Meyerhoff DJ, Gerson J, Norman D, Fein G, Weiner MW (1996) Alzheimer disease and subcortical ischemic vascular dementia: evaluation by combining MR imaging segmentation and H-1 MR spectroscopic imaging. Radiology 198(2): 537-545
    • (1996) Radiology , vol.198 , Issue.2 , pp. 537-545
    • MacKay, S.1    Ezekiel, F.2    Di Sclafani, V.3    Meyerhoff, D.J.4    Gerson, J.5    Norman, D.6    Fein, G.7    Weiner, M.W.8
  • 98
    • 34447100593 scopus 로고    scopus 로고
    • MR spectroscopy in neurodegenerative disease
    • Martin WR (2007) MR spectroscopy in neurodegenerative disease. Mol Imaging Biol 9(4): 196-203. doi: 10. 1007/s11307-007-0087-2
    • (2007) Mol Imaging Biol , vol.9 , Issue.4 , pp. 196-203
    • Martin, W.R.1
  • 99
    • 0029811226 scopus 로고    scopus 로고
    • Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease
    • Masliah E, Alford M, DeTeresa R, Mallory M, Hansen L (1996) Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease. Ann Neurol 40(5): 759-766. doi: 10. 1002/ana. 410400512
    • (1996) Ann Neurol , vol.40 , Issue.5 , pp. 759-766
    • Masliah, E.1    Alford, M.2    DeTeresa, R.3    Mallory, M.4    Hansen, L.5
  • 100
    • 0034963584 scopus 로고    scopus 로고
    • MR spectroscopy quantitation: a review of frequency domain methods
    • Mierisova S, Ala-Korpela M (2001) MR spectroscopy quantitation: a review of frequency domain methods. NMR Biomed 14(4): 247-259
    • (2001) NMR Biomed , vol.14 , Issue.4 , pp. 247-259
    • Mierisova, S.1    Ala-Korpela, M.2
  • 101
    • 52949130629 scopus 로고    scopus 로고
    • 1H NMR spectroscopy of rat brain in vivo at 14. 1Tesla: improvements in quantification of the neurochemical profile
    • Mlynarik V, Cudalbu C, Xin L, Gruetter R (2008a) 1H NMR spectroscopy of rat brain in vivo at 14. 1Tesla: improvements in quantification of the neurochemical profile. J Magn Reson 194 (2): 163-168. doi: S1090-7807(08)00205-X [pii] 10. 1016/j. jmr. 2008. 06. 019
    • (2008) J Magn Reson , vol.194 , Issue.2 , pp. 163-168
    • Mlynarik, V.1    Cudalbu, C.2    Xin, L.3    Gruetter, R.4
  • 102
    • 37549048204 scopus 로고    scopus 로고
    • Quantitative proton spectroscopic imaging of the neurochemical profile in rat brain with microliter resolution at ultra-short echo times
    • Mlynarik V, Kohler I, Gambarota G, Vaslin A, Clarke PG, Gruetter R (2008b) Quantitative proton spectroscopic imaging of the neurochemical profile in rat brain with microliter resolution at ultra-short echo times. Magn Reson Med 59(1): 52-58. doi: 10. 1002/mrm. 21447
    • (2008) Magn Reson Med , vol.59 , Issue.1 , pp. 52-58
    • Mlynarik, V.1    Kohler, I.2    Gambarota, G.3    Vaslin, A.4    Clarke, P.G.5    Gruetter, R.6
  • 103
    • 16844365618 scopus 로고    scopus 로고
    • Conversion from mild cognitive impairment to probable Alzheimer's disease predicted by brain magnetic resonance spectroscopy
    • Modrego PJ, Fayed N, Pina MA (2005) Conversion from mild cognitive impairment to probable Alzheimer's disease predicted by brain magnetic resonance spectroscopy. Am J Psychiatry 162(4): 667-675. doi: 10. 1176/appi. ajp. 162. 4. 667
    • (2005) Am J Psychiatry , vol.162 , Issue.4 , pp. 667-675
    • Modrego, P.J.1    Fayed, N.2    Pina, M.A.3
  • 104
    • 33749245441 scopus 로고    scopus 로고
    • Changes in metabolite ratios after treatment with rivastigmine in Alzheimer's disease: a nonrandomised controlled trial with magnetic resonance spectroscopy
    • Modrego PJ, Pina MA, Fayed N, Diaz M (2006) Changes in metabolite ratios after treatment with rivastigmine in Alzheimer's disease: a nonrandomised controlled trial with magnetic resonance spectroscopy. CNS Drugs 20(10): 867-877
    • (2006) CNS Drugs , vol.20 , Issue.10 , pp. 867-877
    • Modrego, P.J.1    Pina, M.A.2    Fayed, N.3    Diaz, M.4
  • 106
    • 0035089253 scopus 로고    scopus 로고
    • Direct determination of the N-acetyl-L-aspartate synthesis rate in the human brain by (13)C MRS and [1-(13)C]glucose infusion
    • Moreno A, Ross BD, Bluml S (2001) Direct determination of the N-acetyl-L-aspartate synthesis rate in the human brain by (13)C MRS and [1-(13)C]glucose infusion. J Neurochem 77(1): 347-350
    • (2001) J Neurochem , vol.77 , Issue.1 , pp. 347-350
    • Moreno, A.1    Ross, B.D.2    Bluml, S.3
  • 108
    • 0029981856 scopus 로고    scopus 로고
    • An [18F]dopa-PET and clinical study of the rate of progression in Parkinson's disease
    • Morrish PK, Sawle GV, Brooks DJ (1996) An [18F]dopa-PET and clinical study of the rate of progression in Parkinson's disease. Brain 119(Pt 2): 585-591
    • (1996) Brain , vol.119 , pp. 585-591
    • Morrish, P.K.1    Sawle, G.V.2    Brooks, D.J.3
  • 109
    • 0021328595 scopus 로고
    • Parkinson's disease: neuron loss in the nucleus basalis without concomitant Alzheimer's disease
    • Nakano I, Hirano A (1984) Parkinson's disease: neuron loss in the nucleus basalis without concomitant Alzheimer's disease. Ann Neurol 15(5): 415-418. doi: 10. 1002/ana. 410150503
    • (1984) Ann Neurol , vol.15 , Issue.5 , pp. 415-418
    • Nakano, I.1    Hirano, A.2
  • 112
    • 51249181873 scopus 로고
    • Dopaminergic deficiency is more pronounced in putamen than in nucleus caudatus in Parkinson's disease
    • Nyberg P, Nordberg A, Wester P, Winblad B (1983) Dopaminergic deficiency is more pronounced in putamen than in nucleus caudatus in Parkinson's disease. Neurochem Pathology 1(3): 193-202. doi: 10. 1007/BF02834244
    • (1983) Neurochem Pathology , vol.1 , Issue.3 , pp. 193-202
    • Nyberg, P.1    Nordberg, A.2    Wester, P.3    Winblad, B.4
  • 113
    • 0030041034 scopus 로고    scopus 로고
    • Fetal nigral transplantation as a therapy for Parkinson's disease
    • Olanow CW, Kordower JH, Freeman TB (1996) Fetal nigral transplantation as a therapy for Parkinson's disease. Trends Neurosci 19(3): 102-109
    • (1996) Trends Neurosci , vol.19 , Issue.3 , pp. 102-109
    • Olanow, C.W.1    Kordower, J.H.2    Freeman, T.B.3
  • 114
    • 0036707663 scopus 로고    scopus 로고
    • Quantitative 1H magnetic resonance spectroscopy and MRI of Parkinson's disease
    • O'Neill J, Schuff N, Marks WJ Jr, Feiwell R, Aminoff MJ, Weiner MW (2002) Quantitative 1H magnetic resonance spectroscopy and MRI of Parkinson's disease. Mov Disord 17(5): 917-927. doi: 10. 1002/mds. 10214
    • (2002) Mov Disord , vol.17 , Issue.5 , pp. 917-927
    • O'Neill, J.1    Schuff, N.2    Marks, W.J.3    Feiwell, R.4    Aminoff, M.J.5    Weiner, M.W.6
  • 116
    • 32544449312 scopus 로고    scopus 로고
    • Proton MRS of the unilateral substantia nigra in the human brain at 4 tesla: detection of high GABA concentrations
    • Oz G, Terpstra M, Tkac I, Aia P, Lowary J, Tuite PJ, Gruetter R (2006) Proton MRS of the unilateral substantia nigra in the human brain at 4 tesla: detection of high GABA concentrations. Magn Reson Med 55(2): 296-301. doi: 10. 1002/mrm. 20761
    • (2006) Magn Reson Med , vol.55 , Issue.2 , pp. 296-301
    • Oz, G.1    Terpstra, M.2    Tkac, I.3    Aia, P.4    Lowary, J.5    Tuite, P.J.6    Gruetter, R.7
  • 119
    • 77955318369 scopus 로고    scopus 로고
    • A selective 15N-to-(1)H polarization transfer sequence for more sensitive detection of 15N-choline
    • Pfeilsticker JA, Ollerenshaw JE, Norton VA, Weitekamp DP (2010) A selective 15N-to-(1)H polarization transfer sequence for more sensitive detection of 15N-choline. J Magn Reson 205(1): 125-129. doi: S1090-7807(10)00112-6[pii]10. 1016/j. jmr. 2010. 04. 010
    • (2010) J Magn Reson , vol.205 , Issue.1 , pp. 125-129
    • Pfeilsticker, J.A.1    Ollerenshaw, J.E.2    Norton, V.A.3    Weitekamp, D.P.4
  • 120
    • 0033226834 scopus 로고    scopus 로고
    • Toward an in vivo neurochemical profile: quantification of 18 metabolites in short-echo-time (1)H NMR spectra of the rat brain
    • Pfeuffer J, Tkac I, Provencher SW, Gruetter R (1999) Toward an in vivo neurochemical profile: quantification of 18 metabolites in short-echo-time (1)H NMR spectra of the rat brain. J Magn Reson 141(1): 104-120. doi: 10. 1006/jmre. 1999. 1895S1090-7807(99)91895-5[pii]
    • (1999) J Magn Reson , vol.141 , Issue.1 , pp. 104-120
    • Pfeuffer, J.1    Tkac, I.2    Provencher, S.W.3    Gruetter, R.4
  • 122
    • 0034959727 scopus 로고    scopus 로고
    • Automatic quantitation of localized in vivo 1H spectra with LC Model
    • Provencher SW (2001) Automatic quantitation of localized in vivo 1H spectra with LC Model. NMR biomed 14(4): 260-264
    • (2001) NMR biomed , vol.14 , Issue.4 , pp. 260-264
    • Provencher, S.W.1
  • 123
    • 0037248298 scopus 로고    scopus 로고
    • Neurodegeneration: what is it and where are we?
    • Przedborski S, Vila M, Jackson-Lewis V (2003) Neurodegeneration: what is it and where are we? J Clin Invest 111(1): 3-10. doi: 10. 1172/JCI17522
    • (2003) J Clin Invest , vol.111 , Issue.1 , pp. 3-10
    • Przedborski, S.1    Vila, M.2    Jackson-Lewis, V.3
  • 124
    • 34548716597 scopus 로고    scopus 로고
    • In vivo 31P MRS of human brain at high/ultrahigh fields: a quantitative comparison of NMR detection sensitivity and spectral resolution between 4 T and 7 T
    • Qiao H, Zhang X, Zhu XH, Du F, Chen W (2006) In vivo 31P MRS of human brain at high/ultrahigh fields: a quantitative comparison of NMR detection sensitivity and spectral resolution between 4 T and 7 T. Magn Reson Imaging 24(10): 1281-1286. doi: 10. 1016/j. mri. 2006. 08. 002
    • (2006) Magn Reson Imaging , vol.24 , Issue.10 , pp. 1281-1286
    • Qiao, H.1    Zhang, X.2    Zhu, X.H.3    Du, F.4    Chen, W.5
  • 125
    • 0022476631 scopus 로고
    • The use of NMR spectroscopy for the understanding of disease
    • Radda GK (1986) The use of NMR spectroscopy for the understanding of disease. Science 233(4764): 640-645
    • (1986) Science , vol.233 , Issue.4764 , pp. 640-645
    • Radda, G.K.1
  • 127
    • 34250718053 scopus 로고    scopus 로고
    • Recent advances in magnetic resonance neurospectroscopy
    • Rosen Y, Lenkinski RE (2007) Recent advances in magnetic resonance neurospectroscopy. Neurotherapeutics 4(3): 330-345. doi: S1933-7213(07)00082-7[pii]10. 1016/j. nurt. 2007. 04. 009
    • (2007) Neurotherapeutics , vol.4 , Issue.3 , pp. 330-345
    • Rosen, Y.1    Lenkinski, R.E.2
  • 128
    • 0035871761 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy of the human brain
    • Ross B, Bluml S (2001) Magnetic resonance spectroscopy of the human brain. Anat Rec 265(2): 54-84. doi: 10. 1002/ar. 1058[pii]
    • (2001) Anat Rec , vol.265 , Issue.2 , pp. 54-84
    • Ross, B.1    Bluml, S.2
  • 129
    • 0032800442 scopus 로고    scopus 로고
    • In vivo magnetic resonance spectroscopy of human fetal neural transplants
    • Ross BD, Hoang TQ, Bluml S, Dubowitz D, Kopyov OV, Jacques DB, Lin A, Seymour K, Tan J (1999) In vivo magnetic resonance spectroscopy of human fetal neural transplants. NMR Biomed 12(4): 221-236. doi: 10. 1002/(SICI)1099-1492(199906)12: 4\221: AID-NBM582[3. 0. CO; 2-Q[pii]
    • (1999) NMR Biomed , vol.12 , Issue.4 , pp. 221-236
    • Ross, B.D.1    Hoang, T.Q.2    Bluml, S.3    Dubowitz, D.4    Kopyov, O.V.5    Jacques, D.B.6    Lin, A.7    Seymour, K.8    Tan, J.9
  • 130
    • 75749098159 scopus 로고    scopus 로고
    • Hyperpolarized MR imaging: neurologic applications of hyperpolarized metabolism
    • Ross BD, Bhattacharya P, Wagner S, Tran T, Sailasuta N (2010) Hyperpolarized MR imaging: neurologic applications of hyperpolarized metabolism. AJNR Am J Neuroradiol 31(1): 24-33. doi: ajnr. A1790[pii]10. 3174/ajnr. A1790
    • (2010) AJNR Am J Neuroradiol , vol.31 , Issue.1 , pp. 24-33
    • Ross, B.D.1    Bhattacharya, P.2    Wagner, S.3    Tran, T.4    Sailasuta, N.5
  • 132
    • 0027411599 scopus 로고
    • The role of positron emission tomography in the assessment of human neurotransplantation
    • Sawle GV, Myers R (1993) The role of positron emission tomography in the assessment of human neurotransplantation. Trends Neurosci 16(5): 172-176
    • (1993) Trends Neurosci , vol.16 , Issue.5 , pp. 172-176
    • Sawle, G.V.1    Myers, R.2
  • 133
    • 52049104684 scopus 로고    scopus 로고
    • Magnetic resonance imaging and spectroscopy
    • Schaeffter T, Dahnke H (2008) Magnetic resonance imaging and spectroscopy. Handb Exp Pharmacol (185 Pt 1): 75-90. doi: 10. 1007/978-3-540-72718-7_4
    • (2008) Handb Exp Pharmacol , vol.185 , pp. 75-90
    • Schaeffter, T.1    Dahnke, H.2
  • 134
    • 78049471319 scopus 로고    scopus 로고
    • Short echo time proton magnetic resonance spectroscopy in Alzheimer's disease: a longitudinal multiple time point study
    • Schott JM, Frost C, MacManus DG, Ibrahim F, Waldman AD, Fox NC (2010) Short echo time proton magnetic resonance spectroscopy in Alzheimer's disease: a longitudinal multiple time point study. Brain J Neurol 133(11): 3315-3322. doi: 10. 1093/brain/awq208
    • (2010) Brain J Neurol , vol.133 , Issue.11 , pp. 3315-3322
    • Schott, J.M.1    Frost, C.2    MacManus, D.G.3    Ibrahim, F.4    Waldman, A.D.5    Fox, N.C.6
  • 135
    • 73449121913 scopus 로고    scopus 로고
    • Normal cortical energy metabolism in migrainous stroke: A 31P-MR spectroscopy study
    • Schulz UG, Blamire AM, Davies P, Styles P, Rothwell PM (2009) Normal cortical energy metabolism in migrainous stroke: A 31P-MR spectroscopy study. Stroke J cereb circ 40(12): 3740-3744. doi: 10. 1161/STROKEAHA. 109. 558163
    • (2009) Stroke J cereb circ , vol.40 , Issue.12 , pp. 3740-3744
    • Schulz, U.G.1    Blamire, A.M.2    Davies, P.3    Styles, P.4    Rothwell, P.M.5
  • 136
    • 34547670228 scopus 로고    scopus 로고
    • A decrease in N-acetylaspartate and an increase in myoinositol in the anterior cingulate gyrus are associated with behavioral and psychological symptoms in Alzheimer's disease
    • Shinno H, Inagaki T, Miyaoka T, Okazaki S, Kawamukai T, Utani E, Inami Y, Horiguchi J (2007) A decrease in N-acetylaspartate and an increase in myoinositol in the anterior cingulate gyrus are associated with behavioral and psychological symptoms in Alzheimer's disease. J Neurol Sci 260(1-2): 132-138. doi: 10. 1016/j. jns. 2007. 04. 017
    • (2007) J Neurol Sci , vol.260 , Issue.2 , pp. 132-138
    • Shinno, H.1    Inagaki, T.2    Miyaoka, T.3    Okazaki, S.4    Kawamukai, T.5    Utani, E.6    Inami, Y.7    Horiguchi, J.8
  • 137
    • 3242737585 scopus 로고    scopus 로고
    • Energetic basis of brain activity: implications for neuroimaging
    • Shulman RG, Rothman DL, Behar KL, Hyder F (2004) Energetic basis of brain activity: implications for neuroimaging. Trends Neurosci 27(8): 489-495. doi: 10. 1016/j. tins. 2004. 06. 005
    • (2004) Trends Neurosci , vol.27 , Issue.8 , pp. 489-495
    • Shulman, R.G.1    Rothman, D.L.2    Behar, K.L.3    Hyder, F.4
  • 138
    • 0030615222 scopus 로고    scopus 로고
    • In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling
    • Sibson NR, Dhankhar A, Mason GF, Behar KL, Rothman DL, Shulman RG (1997) In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling. Proc Natl Acad Sci U S A 94(6): 2699-2704
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.6 , pp. 2699-2704
    • Sibson, N.R.1    Dhankhar, A.2    Mason, G.F.3    Behar, K.L.4    Rothman, D.L.5    Shulman, R.G.6
  • 140
    • 0029014638 scopus 로고
    • The use of a priori knowledge to quantify short echo in vivo 1H MR spectra
    • Stanley JA, Drost DJ, Williamson PC, Thompson RT (1995) The use of a priori knowledge to quantify short echo in vivo 1H MR spectra. Magn Reson Med 34(1): 17-24
    • (1995) Magn Reson Med , vol.34 , Issue.1 , pp. 17-24
    • Stanley, J.A.1    Drost, D.J.2    Williamson, P.C.3    Thompson, R.T.4
  • 142
    • 34447095438 scopus 로고    scopus 로고
    • Animal models of neurodegenerative disease: insights from in vivo imaging studies
    • Strome EM, Doudet DJ (2007) Animal models of neurodegenerative disease: insights from in vivo imaging studies. Mol Imaging Biol 9(4): 186-195. doi: 10. 1007/s11307-007-0093-4
    • (2007) Mol Imaging Biol , vol.9 , Issue.4 , pp. 186-195
    • Strome, E.M.1    Doudet, D.J.2
  • 146
    • 0018004393 scopus 로고
    • High-resolution 13C nuclear magnetic resonance studies of glucose metabolism in Escherichia coli
    • Ugurbil K, Brown TR, den Hollander JA, Glynn P, Shulman RG (1978) High-resolution 13C nuclear magnetic resonance studies of glucose metabolism in Escherichia coli. Proc Natl Acad Sci U S A 75(8): 3742-3746
    • (1978) Proc Natl Acad Sci U S A , vol.75 , Issue.8 , pp. 3742-3746
    • Ugurbil, K.1    Brown, T.R.2    den Hollander, J.A.3    Glynn, P.4    Shulman, R.G.5
  • 148
    • 0027450301 scopus 로고
    • Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types
    • Urenjak J, Williams SR, Gadian DG, Noble M (1993) Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types. J Neurosci 13(3): 981-989
    • (1993) J Neurosci , vol.13 , Issue.3 , pp. 981-989
    • Urenjak, J.1    Williams, S.R.2    Gadian, D.G.3    Noble, M.4
  • 149
    • 0024273006 scopus 로고
    • Cerebral lactate detected by regional proton magnetic-resonance spectroscopy in a patient with cerebral infarction
    • Vandersprenkel JWB, Luyten PR, Vanrijen PC, Tulleken CAF, Denhollander JA (1988) Cerebral lactate detected by regional proton magnetic-resonance spectroscopy in a patient with cerebral infarction. Stroke 19(12): 1556-1560
    • (1988) Stroke , vol.19 , Issue.12 , pp. 1556-1560
    • Vandersprenkel, J.W.B.1    Luyten, P.R.2    Vanrijen, P.C.3    Tulleken, C.A.F.4    Denhollander, J.A.5
  • 150
    • 0034963583 scopus 로고    scopus 로고
    • MR spectroscopy quantitation: a review of time-domain methods
    • Vanhamme L, Sundin T, Hecke PV, Huffel SV (2001) MR spectroscopy quantitation: a review of time-domain methods. NMR Biomed 14(4): 233-246
    • (2001) NMR Biomed , vol.14 , Issue.4 , pp. 233-246
    • Vanhamme, L.1    Sundin, T.2    Hecke, P.V.3    Huffel, S.V.4
  • 151
    • 0042827614 scopus 로고    scopus 로고
    • The relationship between cognitive impairment and in vivo metabolite ratios in patients with clinical Alzheimer's disease and vascular dementia: a proton magnetic resonance spectroscopy study
    • Waldman AD, Rai GS (2003) The relationship between cognitive impairment and in vivo metabolite ratios in patients with clinical Alzheimer's disease and vascular dementia: a proton magnetic resonance spectroscopy study. Neuroradiol 45(8): 507-512. doi: 10. 1007/s00234-003-1040-y
    • (2003) Neuroradiol , vol.45 , Issue.8 , pp. 507-512
    • Waldman, A.D.1    Rai, G.S.2
  • 152
    • 0020072221 scopus 로고
    • Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain
    • Whitehouse PJ, Price DL, Struble RG, Clark AW, Coyle JT, Delon MR (1982) Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science 215(4537): 1237-1239
    • (1982) Science , vol.215 , Issue.4537 , pp. 1237-1239
    • Whitehouse, P.J.1    Price, D.L.2    Struble, R.G.3    Clark, A.W.4    Coyle, J.T.5    Delon, M.R.6
  • 153
    • 78651519725 scopus 로고    scopus 로고
    • 31P magnetic resonance spectroscopic imaging with polarisation transfer of phosphomono-and diesters at 3 T in the human brain: relation with age and spatial differences
    • Wijnen JP, Scheenen TW, Klomp DW, Heerschap A (2010) 31P magnetic resonance spectroscopic imaging with polarisation transfer of phosphomono-and diesters at 3 T in the human brain: relation with age and spatial differences. NMR Biomed 23(8): 968-976. doi: 10. 1002/nbm. 1523
    • (2010) NMR Biomed , vol.23 , Issue.8 , pp. 968-976
    • Wijnen, J.P.1    Scheenen, T.W.2    Klomp, D.W.3    Heerschap, A.4
  • 154
    • 47549094930 scopus 로고    scopus 로고
    • Use of 31P magnetic resonance spectroscopy to study the effect of cortical magnesium and energy metabolism after subarachnoid hemorrhage
    • Yang H, Tang X, Tan L, Zeng L, Hu Z (2008) Use of 31P magnetic resonance spectroscopy to study the effect of cortical magnesium and energy metabolism after subarachnoid hemorrhage. Cerebrovasc Dis 26(3): 223-230. doi: 10. 1159/000147448
    • (2008) Cerebrovasc Dis , vol.26 , Issue.3 , pp. 223-230
    • Yang, H.1    Tang, X.2    Tan, L.3    Zeng, L.4    Hu, Z.5
  • 155
    • 84934435318 scopus 로고    scopus 로고
    • Advanced in vivo heteronuclear MRS approaches for studying brain bioenergetics driven by mitochondria
    • Zhu XH, Du F, Zhang N, Zhang Y, Lei H, Zhang X, Qiao H, Ugurbil K, Chen W (2009) Advanced in vivo heteronuclear MRS approaches for studying brain bioenergetics driven by mitochondria. Methods Mol Biol 489: 317-357. doi: 10. 1007/978-1-59745-543-5_15
    • (2009) Methods Mol Biol , vol.489 , pp. 317-357
    • Zhu, X.H.1    Du, F.2    Zhang, N.3    Zhang, Y.4    Lei, H.5    Zhang, X.6    Qiao, H.7    Ugurbil, K.8    Chen, W.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.