In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 6, 1997, Pages 2699-2704

  Sibson, N R ^a   Dhankhar, A ^a   Mason, G F ^b   Behar, K L ^a   Rothman, D L ^a   Shulman, R G ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Detoxification; Hyperammonemia; Neurotransmitter cycle

Indexed keywords

ANIMALIA;

AMMONIA; CARBON; GLUCOSE; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; GLUTAMINE; CARBON 13;

ANIMAL; ARTICLE; BRAIN; CHEMICAL MODEL; CITRIC ACID CYCLE; DRUG EFFECT; KINETICS; MALE; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; SPRAGUE DAWLEY RAT; THEORETICAL MODEL; AMINO ACID METABOLISM; ANIMAL EXPERIMENT; BRAIN METABOLISM; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DETOXIFICATION; ENZYME ACTIVITY; HYPERAMMONEMIA; ISOTOPE LABELING; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL;

AMMONIA; ANIMALS; BRAIN; CARBON ISOTOPES; CITRIC ACID CYCLE; GLUCOSE; GLUTAMATE-AMMONIA LIGASE; GLUTAMIC ACID; GLUTAMINE; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MODELS, CHEMICAL; MODELS, THEORETICAL; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030615222     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.6.2699     Document Type: Article

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