-
1
-
-
0032493914
-
Choline, a vital amine
-
Blusztajn JK.Choline, a vital amine.Science 1998;281(5378):794-795.
-
(1998)
Science
, vol.281
, Issue.5378
, pp. 794-795
-
-
Blusztajn, J.K.1
-
2
-
-
31144450053
-
Current pharmacotherapy for Alzheimer's disease
-
Lleo A, Greenberg SM, Growdon JH.Current pharmacotherapy for Alzheimer's disease.Annu Rev Med 2006;57:513-533.
-
(2006)
Annu Rev Med
, vol.57
, pp. 513-533
-
-
Lleo, A.1
Greenberg, S.M.2
Growdon, J.H.3
-
3
-
-
66849138226
-
Changes in choline metabolism as potential biomarkers of phospholipase C gamma 1 inhibition in human prostate cancer cells
-
Beloueche-Babari M, Peak JC, Jackson LE, Tiet MY, Leach MO, Eccles SA.Changes in choline metabolism as potential biomarkers of phospholipase C gamma 1 inhibition in human prostate cancer cells.Mol Cancer Ther 2009;8(5):1305-1311.
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.5
, pp. 1305-1311
-
-
Beloueche-Babari, M.1
Peak, J.C.2
Jackson, L.E.3
Tiet, M.Y.4
Leach, M.O.5
Eccles, S.A.6
-
4
-
-
0037151369
-
Clinical utility of proton magnetic resonance spectroscopy in characterizing breast lesions
-
Katz-Brull R, Lavin PT, Lenkinski RE.Clinical utility of proton magnetic resonance spectroscopy in characterizing breast lesions.J Natl Cancer Inst 2002;94(16):1197-1203.
-
(2002)
J Natl Cancer Inst
, vol.94
, Issue.16
, pp. 1197-1203
-
-
Katz-Brull, R.1
Lavin, P.T.2
Lenkinski, R.E.3
-
5
-
-
60449120319
-
The correlation between H-1 MRS choline concentrations and MR diffusion trace values in human brain tumors
-
Wagnerova D, Jiru F, Dezortova M, Vargova L, Sykova E, Hajek M.The correlation between H-1 MRS choline concentrations and MR diffusion trace values in human brain tumors.Magn Reson Mater Phys Biol Med 2009;22(1):19-31.
-
(2009)
Magn Reson Mater Phys Biol Med
, vol.22
, Issue.1
, pp. 19-31
-
-
Wagnerova, D.1
Jiru, F.2
Dezortova, M.3
Vargova, L.4
Sykova, E.5
Hajek, M.6
-
6
-
-
31544473808
-
Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models
-
Al-Saffar NMS, Troy H, de Molina AR, Jackson LE, Madhu B, Griffiths JR, Leach MO, Workman P, Lacal JC, Judson IR, Chung YL.Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.Cancer Res 2006;66(1):427-434.
-
(2006)
Cancer Res
, vol.66
, Issue.1
, pp. 427-434
-
-
Al-Saffar, N.M.S.1
Troy, H.2
de Molina, A.R.3
Jackson, L.E.4
Madhu, B.5
Griffiths, J.R.6
Leach, M.O.7
Workman, P.8
Lacal, J.C.9
Judson, I.R.10
Chung, Y.L.11
-
7
-
-
17144420870
-
Magnetic resonance spectroscopy monitoring of mitogen-activated protein kinase signaling inhibition
-
Beloueche-Babari M, Jackson LE, Al-Saffar NM, Workman P, Leach MO, Ronen SM.Magnetic resonance spectroscopy monitoring of mitogen-activated protein kinase signaling inhibition.Cancer Res 2005;65(8):3356-3363.
-
(2005)
Cancer Res
, vol.65
, Issue.8
, pp. 3356-3363
-
-
Beloueche-Babari, M.1
Jackson, L.E.2
Al-Saffar, N.M.3
Workman, P.4
Leach, M.O.5
Ronen, S.M.6
-
8
-
-
28244464886
-
RNA interference-mediated choline kinase suppression in breast cancer cells induces differentiation and reduces proliferation
-
Glunde K, Raman V, Mori N, Bhujwalla ZM.RNA interference-mediated choline kinase suppression in breast cancer cells induces differentiation and reduces proliferation.Cancer Res 2005;65(23):11034-11043.
-
(2005)
Cancer Res
, vol.65
, Issue.23
, pp. 11034-11043
-
-
Glunde, K.1
Raman, V.2
Mori, N.3
Bhujwalla, Z.M.4
-
9
-
-
0030017723
-
Kinetics of choline transport and phosphorylation in human breast cancer cells; NMR application of the zero trans method
-
Katz-Brull R, Degani H.Kinetics of choline transport and phosphorylation in human breast cancer cells; NMR application of the zero trans method.Anticancer Res 1996;16:1375-1380.
-
(1996)
Anticancer Res
, vol.16
, pp. 1375-1380
-
-
Katz-Brull, R.1
Degani, H.2
-
10
-
-
0038124366
-
Investigations of a common genetic methyltransferase (BHMT) variant in betaine-homocysteine in coronary artery disease
-
Weisberg IS, Park E, Ballman KV, Berger P, Nunn M, Suh DS, Breksa AP, Garrow TA, Rozen R.Investigations of a common genetic methyltransferase (BHMT) variant in betaine-homocysteine in coronary artery disease.Atherosclerosis 2003;167(2):205-214.
-
(2003)
Atherosclerosis
, vol.167
, Issue.2
, pp. 205-214
-
-
Weisberg, I.S.1
Park, E.2
Ballman, K.V.3
Berger, P.4
Nunn, M.5
Suh, D.S.6
Breksa, A.P.7
Garrow, T.A.8
Rozen, R.9
-
11
-
-
20444382748
-
Direct detection of brain acetylcholine synthesis by magnetic resonance spectroscopy
-
Katz-Brull R, Koudinov AR, Degani H.Direct detection of brain acetylcholine synthesis by magnetic resonance spectroscopy.Brain Res 2005;1048(1-2):202-210.
-
(2005)
Brain Res
, vol.1048
, Issue.1-2
, pp. 202-210
-
-
Katz-Brull, R.1
Koudinov, A.R.2
Degani, H.3
-
12
-
-
0034952347
-
Differential routing of choline in implanted breast cancer and normal organs
-
Katz-Brull R, Margalit R, Degani H.Differential routing of choline in implanted breast cancer and normal organs.Magn Reson Med 2001;46(1):31-38.
-
(2001)
Magn Reson Med
, vol.46
, Issue.1
, pp. 31-38
-
-
Katz-Brull, R.1
Margalit, R.2
Degani, H.3
-
13
-
-
0042763165
-
Increase in signal-to-noise ratio of>10,000 times in liquid-state NMR
-
Ardenkjaer-Larsen JH, Fridlund B, Gram A, Hansson G, Hansson L, Lerche MH, Servin R, Thaning M, Golman K.Increase in signal-to-noise ratio of>10, 000 times in liquid-state NMR.Proc Natl Acad Sci USA 2003;100(18):10158-10163.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.18
, pp. 10158-10163
-
-
Ardenkjaer-Larsen, J.H.1
Fridlund, B.2
Gram, A.3
Hansson, G.4
Hansson, L.5
Lerche, M.H.6
Servin, R.7
Thaning, M.8
Golman, K.9
-
14
-
-
34547746449
-
In vivo (13)carbon metabolic imaging at 3T with hyperpolarized C-13-1-pyruvate
-
Kohler SJ, Yen Y, Wolber J, Chen AP, Albers MJ, Bok R, Zhang V, Tropp J, Nelson S, Vigneron DB, Kurhanewicz J, Hurd RE.In vivo (13)carbon metabolic imaging at 3T with hyperpolarized C-13-1-pyruvate.Magn Reson Med 2007;58(1):65-69.
-
(2007)
Magn Reson Med
, vol.58
, Issue.1
, pp. 65-69
-
-
Kohler, S.J.1
Yen, Y.2
Wolber, J.3
Chen, A.P.4
Albers, M.J.5
Bok, R.6
Zhang, V.7
Tropp, J.8
Nelson, S.9
Vigneron, D.B.10
Kurhanewicz, J.11
Hurd, R.E.12
-
15
-
-
73949133557
-
Production of hyperpolarized [1,4-C-13(2)]malate from [1,4-C-13(2)]fumarate is a marker of cell necrosis and treatment response in tumors
-
Gallagher FA, Kettunen MI, Hu DE, Jensen PR, in't Zandt R, Karlsson M, Gisselsson A, Nelson SK, Witney TH, Bohndiek SE, Hansson G, Peitersen T, Lerche MH, Brindle KM.Production of hyperpolarized [1, 4-C-13(2)]malate from [1, 4-C-13(2)]fumarate is a marker of cell necrosis and treatment response in tumors.Proc Natl Acad Sci USA 2009;106(47):19801-19806.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.47
, pp. 19801-19806
-
-
Gallagher, F.A.1
Kettunen, M.I.2
Hu, D.E.3
Jensen, P.R.4
in't Zandt, R.5
Karlsson, M.6
Gisselsson, A.7
Nelson, S.K.8
Witney, T.H.9
Bohndiek, S.E.10
Hansson, G.11
Peitersen, T.12
Lerche, M.H.13
Brindle, K.M.14
-
16
-
-
79959546848
-
Cerebral perfusion imaging with a hyperpolarized freely diffusible contrast agent
-
Grant A, Vinogradov E, Wang X, Alsop D.Cerebral perfusion imaging with a hyperpolarized freely diffusible contrast agent.Proc Int Soc Mag Reson Med 2010; (18):3289.
-
(2010)
Proc Int Soc Mag Reson Med
, Issue.18
, pp. 3289
-
-
Grant, A.1
Vinogradov, E.2
Wang, X.3
Alsop, D.4
-
17
-
-
79959563103
-
In vivo detection of rat brain metabolism using hyperpolarized acetate
-
Mishkovsky M, Comment A, Gruetter R.In vivo detection of rat brain metabolism using hyperpolarized acetate.Proc Int Soc Mag Reson Med 2010; (18):3278.
-
(2010)
Proc Int Soc Mag Reson Med
, Issue.18
, pp. 3278
-
-
Mishkovsky, M.1
Comment, A.2
Gruetter, R.3
-
18
-
-
72249086965
-
Hyperpolarized [2-C-13]-fructose: a hemiketal DNP substrate for in vivo metabolic imaging
-
Keshari KR, Wilson DM, Chen AP, Bok R, Larson PEZ, Hu S, Van Criekinge M, Macdonald JM, Vigneron DB, Kurhanewicz J.Hyperpolarized [2-C-13]-fructose: a hemiketal DNP substrate for in vivo metabolic imaging.J Am Chem Soc 2009;131(48):17591-17596.
-
(2009)
J Am Chem Soc
, vol.131
, Issue.48
, pp. 17591-17596
-
-
Keshari, K.R.1
Wilson, D.M.2
Chen, A.P.3
Bok, R.4
Larson, P.E.Z.5
Hu, S.6
Van Criekinge, M.7
Macdonald, J.M.8
Vigneron, D.B.9
Kurhanewicz, J.10
-
19
-
-
77954450961
-
Imaging of branched chain amino acid metabolism in tumors with hyperpolarized 13C ketoisocaproate
-
Karlsson M, Jensen PR, t Zandt R, Gisselsson A, Hansson G, Duus JØ, Meier S, Lerche MH.Imaging of branched chain amino acid metabolism in tumors with hyperpolarized 13C ketoisocaproate.Int J Cancer 2009;127(3):729-736.
-
(2009)
Int J Cancer
, vol.127
, Issue.3
, pp. 729-736
-
-
Karlsson, M.1
Jensen, P.R.2
t Zandt, R.3
Gisselsson, A.4
Hansson, G.5
Duus, J.6
Meier, S.7
Lerche, M.H.8
-
20
-
-
33846965675
-
Deuterium substitution effect on relaxation times (Desert) and its application to study of conformation of some purine nucleoside derivatives
-
Akasaka K, Imoto T, Shibata S, Hatano H.Deuterium substitution effect on relaxation times (Desert) and its application to study of conformation of some purine nucleoside derivatives.J Magn Res 1975;18(2):328-343.
-
(1975)
J Magn Res
, vol.18
, Issue.2
, pp. 328-343
-
-
Akasaka, K.1
Imoto, T.2
Shibata, S.3
Hatano, H.4
-
22
-
-
0016468979
-
Rapid radiochemical method for determination of choline-acetyltransferase
-
Fonnum F.Rapid radiochemical method for determination of choline-acetyltransferase.J Neurochem 1975;24(2):407-409.
-
(1975)
J Neurochem
, vol.24
, Issue.2
, pp. 407-409
-
-
Fonnum, F.1
-
23
-
-
0022366311
-
Comparative enzymatic acetylation of carnitine and choline by human placenta syncytiotrophoblast membrane vesicles
-
Jarmer S, Shoaf AR, Harbison RD.Comparative enzymatic acetylation of carnitine and choline by human placenta syncytiotrophoblast membrane vesicles.Teratog Carcinog Mutagen 1985;5(6):445-461.
-
(1985)
Teratog Carcinog Mutagen
, vol.5
, Issue.6
, pp. 445-461
-
-
Jarmer, S.1
Shoaf, A.R.2
Harbison, R.D.3
-
24
-
-
41849121889
-
Therapeutic target metabolism observed using hyperpolarized N-15 choline
-
Gabellieri C, Reynolds S, Lavie A, Payne GS, Leach MO, Eykyn TR.Therapeutic target metabolism observed using hyperpolarized N-15 choline.J Am Chem Soc 2008;130(14):4598-4599.
-
(2008)
J Am Chem Soc
, vol.130
, Issue.14
, pp. 4598-4599
-
-
Gabellieri, C.1
Reynolds, S.2
Lavie, A.3
Payne, G.S.4
Leach, M.O.5
Eykyn, T.R.6
-
25
-
-
77952914139
-
Feasibility of in vivo N-15 MRS detection of hyperpolarized N-15 labeled choline in rats
-
Cudalbu C, Comment A, Kurdzesau F, van Heeswijk RB, Uffmann K, Jannin S, Denisov V, Kirik D, Gruetter R.Feasibility of in vivo N-15 MRS detection of hyperpolarized N-15 labeled choline in rats.Phys Chem Chem Phys12(22):5818-5823.
-
Phys Chem Chem Phys
, vol.12
, Issue.22
, pp. 5818-5823
-
-
Cudalbu, C.1
Comment, A.2
Kurdzesau, F.3
van Heeswijk, R.B.4
Uffmann, K.5
Jannin, S.6
Denisov, V.7
Kirik, D.8
Gruetter, R.9
-
26
-
-
70450202944
-
Proton NMR of 15N-choline metabolites enhanced by dynamic nuclear polarization
-
Sarkar R, Comment A, Vasos PR, Jannin S, Gruetter R, Bodenhausen G, Hall H, Kirik D, Denisov VP.Proton NMR of 15N-choline metabolites enhanced by dynamic nuclear polarization.J Am Chem Soc 2009;131(44):16014-16015.
-
(2009)
J Am Chem Soc
, vol.131
, Issue.44
, pp. 16014-16015
-
-
Sarkar, R.1
Comment, A.2
Vasos, P.R.3
Jannin, S.4
Gruetter, R.5
Bodenhausen, G.6
Hall, H.7
Kirik, D.8
Denisov, V.P.9
-
27
-
-
0016290837
-
Mechanism of action of choline acetyltransferase
-
Currier SF, Mautner HG.Mechanism of action of choline acetyltransferase.Proc Natl Acad Sci USA 1974;71(9):3355-3358.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, Issue.9
, pp. 3355-3358
-
-
Currier, S.F.1
Mautner, H.G.2
-
28
-
-
0035116915
-
Characterization of the blood-brain barrier choline transporter using the in situ rat brain perfusion technique
-
Allen DD, Smith QR.Characterization of the blood-brain barrier choline transporter using the in situ rat brain perfusion technique.J Neurochem 2001;76(4):1032-1041.
-
(2001)
J Neurochem
, vol.76
, Issue.4
, pp. 1032-1041
-
-
Allen, D.D.1
Smith, Q.R.2
-
29
-
-
0028893043
-
3,4-Diaminopyridine and choline increase in vivo acetylcholine release in rat striatum
-
Buyukuysal RL, Ulus IH, Aydin S, Kiran BK.3, 4-Diaminopyridine and choline increase in vivo acetylcholine release in rat striatum.Eur J Pharmacol 1995;281(2):179-185.
-
(1995)
Eur J Pharmacol
, vol.281
, Issue.2
, pp. 179-185
-
-
Buyukuysal, R.L.1
Ulus, I.H.2
Aydin, S.3
Kiran, B.K.4
-
30
-
-
0021057355
-
Labeled choline and phosphorylcholine - body distribution and brain autoradiography - concise communication
-
Friedland RP, Mathis CA, Budinger TF, Moyer BR, Rosen M.Labeled choline and phosphorylcholine - body distribution and brain autoradiography - concise communication.J Nucl Med 1983;24(9):812-815.
-
(1983)
J Nucl Med
, vol.24
, Issue.9
, pp. 812-815
-
-
Friedland, R.P.1
Mathis, C.A.2
Budinger, T.F.3
Moyer, B.R.4
Rosen, M.5
-
31
-
-
0016209722
-
The distribution in the rabbit of choline administered by injection or infusion
-
Gardiner JE, Gwee MCE.The distribution in the rabbit of choline administered by injection or infusion.J Physiol Lond 1974;239(3):459-476.
-
(1974)
J Physiol Lond
, vol.239
, Issue.3
, pp. 459-476
-
-
Gardiner, J.E.1
Gwee, M.C.E.2
-
32
-
-
0016736953
-
Distribution and metabolism of intravenously administered choline[methyl- 3-H] and synthesis in vivo of acetylcholine in various tissues of guinea pigs
-
Haubrich DR, Wang PF, Wedeking PW.Distribution and metabolism of intravenously administered choline[methyl- 3-H] and synthesis in vivo of acetylcholine in various tissues of guinea pigs.J Pharmacol Exp Ther 1975;193(1):246-255.
-
(1975)
J Pharmacol Exp Ther
, vol.193
, Issue.1
, pp. 246-255
-
-
Haubrich, D.R.1
Wang, P.F.2
Wedeking, P.W.3
-
33
-
-
0028938534
-
Choline enhances scopolamine-induced acetylcholine-release in dorsal hippocampus of conscious
-
Jackson DA, Kischka U, Wurtman RJ.Choline enhances scopolamine-induced acetylcholine-release in dorsal hippocampus of conscious, freely-moving rats. Life Sci 1994;56(1):45-49.
-
(1994)
freely-moving rats. Life Sci
, vol.56
, Issue.1
, pp. 45-49
-
-
Jackson, D.A.1
Kischka, U.2
Wurtman, R.J.3
-
34
-
-
0030886327
-
Acetylcholine release and choline availability in rat hippocampus: effects of exogenous choline and nicotinamide
-
Koppen A, Klein J, Erb C, Loffelholz K.Acetylcholine release and choline availability in rat hippocampus: effects of exogenous choline and nicotinamide.J Pharmacol Exp Ther 1997;282(3):1139-1145.
-
(1997)
J Pharmacol Exp Ther
, vol.282
, Issue.3
, pp. 1139-1145
-
-
Koppen, A.1
Klein, J.2
Erb, C.3
Loffelholz, K.4
-
35
-
-
0037720339
-
Intravenously injected CDP-choline increases blood pressure and reverses hypotension in haemorhagic shock: effect is mediated by central cholinergic activation
-
Savci V, Goktalay G, Cansev M, Cavun S, Yilmaz MS, Ulus IH.Intravenously injected CDP-choline increases blood pressure and reverses hypotension in haemorhagic shock: effect is mediated by central cholinergic activation.Eur J Pharmacol 2003;468(2):129-139.
-
(2003)
Eur J Pharmacol
, vol.468
, Issue.2
, pp. 129-139
-
-
Savci, V.1
Goktalay, G.2
Cansev, M.3
Cavun, S.4
Yilmaz, M.S.5
Ulus, I.H.6
-
36
-
-
70349264451
-
Choline acetyltransferase activity in vascular dementia and stroke
-
Sharp SI, Francis PT, Elliott MSJ, Kalaria RN, Bajic N, Hortobagyi T, Ballard CG.Choline acetyltransferase activity in vascular dementia and stroke.Dement Geriatr Cogn Disord 2009;28(3):233-238.
-
(2009)
Dement Geriatr Cogn Disord
, vol.28
, Issue.3
, pp. 233-238
-
-
Sharp, S.I.1
Francis, P.T.2
Elliott, M.S.J.3
Kalaria, R.N.4
Bajic, N.5
Hortobagyi, T.6
Ballard, C.G.7
-
38
-
-
0020579903
-
Dissimilar effects in acute toxicity studies of CDP-choline and choline
-
Agut J, Font E, Sacristan A, Ortiz JA.Dissimilar effects in acute toxicity studies of CDP-choline and choline.Arznemittel Forsch 1983;33(7a):1016-1018.
-
(1983)
Arznemittel Forsch
, vol.33 a
, Issue.7
, pp. 1016-1018
-
-
Agut, J.1
Font, E.2
Sacristan, A.3
Ortiz, J.A.4
-
39
-
-
34447504777
-
Applications of DNP-NMR for the measurement of heteronuclear T-1 relaxation times
-
Day IJ, Mitchell JC, Snowden MJ, Davis AL.Applications of DNP-NMR for the measurement of heteronuclear T-1 relaxation times.J Magn Reson 2007;187(2):216-224.
-
(2007)
J Magn Reson
, vol.187
, Issue.2
, pp. 216-224
-
-
Day, I.J.1
Mitchell, J.C.2
Snowden, M.J.3
Davis, A.L.4
-
40
-
-
34249290676
-
Nitrogen-15 magnetic resonance spectroscopy. I. Chemical Shifts
-
Lambert JB, Binsch G, Roberts JD.Nitrogen-15 magnetic resonance spectroscopy. I. Chemical Shifts.Proc Natl Acad Sci USA 1964;51(5):735-737.
-
(1964)
Proc Natl Acad Sci USA
, vol.51
, Issue.5
, pp. 735-737
-
-
Lambert, J.B.1
Binsch, G.2
Roberts, J.D.3
-
41
-
-
0020858714
-
N-14 nuclear magnetic resonance spectroscopy of mammalian tissues
-
Balaban RS, Knepper MA.N-14 nuclear magnetic resonance spectroscopy of mammalian tissues.Am J Physiol 1983;245(5):439-444.
-
(1983)
Am J Physiol
, vol.245
, Issue.5
, pp. 439-444
-
-
Balaban, R.S.1
Knepper, M.A.2
|