Intrathecal shRNA-AAV9 inhibits target protein expression in the spinal cord and dorsal root ganglia of adult mice

Human Gene Therapy Methods

Volumn 23, Issue 2, 2012, Pages 119-127

  Hirai, Takashi ^a   Enomoto, Mitsuhiro ^a   Machida, Akira ^a   Yamamoto, Mariko ^a   Kuwahara, Hiroya ^a   Tajiri, Mio ^a   Hirai, Yukihiko ^b   Sotome, Shinichi ^a   Mizusawa, Hidehiro ^a   Shinomiya, Kenichi ^a   Okawa, Atsushi ^a   Yokota, Takanori ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; SHORT HAIRPIN RNA; PRIMER DNA; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DIAGNOSIS RELATED GROUP; DORSAL ROOT; DRUG EFFECT; FEMALE; GENE SEQUENCE; GENE SILENCING; LUMBAR SPINAL CORD; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; SPINAL GANGLION; ANIMAL; GENE EXPRESSION REGULATION; GENE THERAPY; GENE VECTOR; GENETICS; HEAT; INSTITUTE FOR CANCER RESEARCH MOUSE; INTRASPINAL DRUG ADMINISTRATION; METABOLISM; METHODOLOGY; NORTHERN BLOTTING; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; ROTAROD TEST; SPINAL CORD; STIMULATION; TOUCH; WESTERN BLOTTING;

ADENO-ASSOCIATED VIRUS; MUS;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; DEPENDOVIRUS; DNA PRIMERS; FEMALE; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; GENETIC THERAPY; GENETIC VECTORS; HOT TEMPERATURE; INJECTIONS, SPINAL; MICE; MICE, INBRED ICR; PHYSICAL STIMULATION; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; ROTAROD PERFORMANCE TEST; SPINAL CORD; SUPEROXIDE DISMUTASE; TOUCH;

EID: 84872047670     PISSN: 19466536     EISSN: 19466544     Source Type: Journal    
DOI: 10.1089/hgtb.2012.035     Document Type: Article

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