Metabonomic investigation of liver profiles of nonpolar metabolites obtained from alcohol-dosed rats and mice using high mass accuracy MS n analysis

Journal of Proteome Research

Volumn 10, Issue 2, 2011, Pages 705-713

  Loftus, Neil ^a   Barnes, Alan ^a   Ashton, Simon ^a   Michopoulos, Filippos ^b,c   Theodoridis, Georgios ^b   Wilson, Ian ^c   Ji, Cheng ^d   Kaplowitz, Neil ^d  

^a SHIMADZU CORPORATION   (United Kingdom)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^c ASTRAZENECA   (United Kingdom)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Alcohol; Ethanol; LC MS; Lipids; Liver; Metabolite profiling; Metabolomics; Metabonomics

Indexed keywords

ADRENIC ACID; ALCOHOL; ARACHIDONIC ACID; CHOLESTEROL; DOCOSAHEXAENOIC ACID; DOCOSAPENTAENOIC ACID; FATTY ACID ESTER; GAMMA LINOLENIC ACID; GLYCEROLIPID; GLYCEROPHOSPHOLIPID; ICOSAPENTAENOIC ACID; ICOSATRIENOIC ACID; LINOLEIC ACID ETHYL ESTER; OLEIC ACID ETHYL ESTER; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; RETINOL; RETINOL PALMITATE; TRIACYLGLYCEROL;

ALCOHOL CONSUMPTION; ALCOHOL LIVER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; LIQUID CHROMATOGRAPHY; LIVER; MALE; MASS SPECTROMETRY; METABOLITE; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; QUALITY CONTROL; RAT; UPREGULATION;

ALCOHOL DRINKING; ANIMALS; CHROMATOGRAPHY, LIQUID; ETHANOL; LIPID METABOLISM; LIVER; MALE; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; MICE; MICE, INBRED C57BL; OLEIC ACIDS; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, WISTAR;

ANIMALIA; MUS; RATTUS; RODENTIA;

EID: 79955371604     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr100885w     Document Type: Article

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