Nonreceptor tyrosine phosphatase Shp2 promotes adipogenesis through inhibition of p38 MAP kinase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 1, 2013, Pages

  He, Zhao ^a   Zhu, Helen H ^a   Bauler, Timothy J ^b   Wang, Jing ^a   Ciaraldi, Theodore ^c   Alderson, Nazilla ^a   Li, Shuangwei ^a   Raquil, Marie Astrid ^a   Ji, Kaihong ^a   Wang, Shufen ^a   Shao, Jianhua ^d   Henry, Robert R ^c   King, Philip D ^b   Feng, Gen Sheng ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Dephosphorylation; Preadipocyte; Substrate trapping; Transduction

Indexed keywords

E1A ASSOCIATED P300 PROTEIN; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN TYROSINE PHOSPHATASE SHP 2;

ADIPOGENESIS; ADIPOSE TISSUE; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CELL DIFFERENTIATION; CONTROLLED STUDY; DISEASE SEVERITY; EMBRYONIC STEM CELL; ENZYME INHIBITION; ERYTHROCYTOSIS; FATTY LIVER; HUMAN; LIPODYSTROPHY; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; WHITE ADIPOSE TISSUE;

ADIPOGENESIS; ADIPOSE TISSUE; ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; DNA PRIMERS; E1A-ASSOCIATED P300 PROTEIN; GENE DELETION; LEPTIN; LIPODYSTROPHY; MICE; MICE, KNOCKOUT; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PPAR GAMMA; PROTEIN KINASES; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANIMALIA; MAMMALIA; MUS;

EID: 84871987193     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1213000110     Document Type: Article

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