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Volumn , Issue , 2009, Pages

Antiretroviral-related adipocyte dysfunction and lipodystrophy in HIV-infected patients: Alteration of the PPARγ-dependent pathways

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ABACAVIR; AMPRENAVIR; ANTIRETROVIRUS AGENT; ATAZANAVIR; DIDANOSINE; EFAVIRENZ; INDINAVIR; IRBESARTAN; LAMIN A; LAMIVUDINE; LAMIVUDINE PLUS NEVIRAPINE PLUS STAVUDINE; LAMIVUDINE PLUS ZIDOVUDINE; LOPINAVIR PLUS RITONAVIR; MESSENGER RNA; NELFINAVIR; NEVIRAPINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; PIOGLITAZONE; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; ROSIGLITAZONE; SAQUINAVIR; STAVUDINE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TELMISARTAN; TENOFOVIR; ZIDOVUDINE;

EID: 60049099162     PISSN: 16874757     EISSN: 16874765     Source Type: Journal    
DOI: 10.1155/2009/507141     Document Type: Review
Times cited : (29)

References (103)
  • 1
    • 2342441342 scopus 로고    scopus 로고
    • Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations
    • Gougeon M.-L., Pénicaud L., Fromenty B., Leclercq P., Viard J.-P., Capeau J., Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations Antiviral Therapy 2004 9 2 161 177
    • (2004) Antiviral Therapy , vol.9 , Issue.2 , pp. 161-177
    • Gougeon, M.-L.1    Pénicaud, L.2    Fromenty, B.3    Leclercq, P.4    Viard, J.-P.5    Capeau, J.6
  • 2
    • 36448962356 scopus 로고    scopus 로고
    • Lipodystrophy in HIV 1-infected patients: Lessons for obesity research
    • Villarroya F., Domingo P., Giralt M., Lipodystrophy in HIV 1-infected patients: lessons for obesity research International Journal of Obesity 2007 31 12 1763 1776
    • (2007) International Journal of Obesity , vol.31 , Issue.12 , pp. 1763-1776
    • Villarroya, F.1    Domingo, P.2    Giralt, M.3
  • 3
    • 11344293751 scopus 로고    scopus 로고
    • Cardiovascular risk and body-fat abnormalities in HIV-infected adults
    • Grinspoon S., Carr A., Cardiovascular risk and body-fat abnormalities in HIV-infected adults The New England Journal of Medicine 2005 352 1 48 62
    • (2005) The New England Journal of Medicine , vol.352 , Issue.1 , pp. 48-62
    • Grinspoon, S.1    Carr, A.2
  • 4
    • 11144314750 scopus 로고    scopus 로고
    • Complications associated with NRTI therapy: Update on clinical features and possible pathogenic mechanisms
    • Nolan D., Mallal S., Complications associated with NRTI therapy: update on clinical features and possible pathogenic mechanisms Antiviral Therapy 2004 9 6 849 863
    • (2004) Antiviral Therapy , vol.9 , Issue.6 , pp. 849-863
    • Nolan, D.1    Mallal, S.2
  • 5
    • 33749366275 scopus 로고    scopus 로고
    • HIV-1 infection alters gene expression in adipose tissue, which contributes to HIV-1/HAART-associated lipodystrophy
    • Giralt M., Domingo P., Guallar J. P., HIV-1 infection alters gene expression in adipose tissue, which contributes to HIV-1/HAART-associated lipodystrophy Antiviral Therapy 2006 11 6 729 740
    • (2006) Antiviral Therapy , vol.11 , Issue.6 , pp. 729-740
    • Giralt, M.1    Domingo, P.2    Guallar, J.P.3
  • 7
    • 33750132462 scopus 로고    scopus 로고
    • The long-term consequences of antiretroviral therapy: A review
    • Boyd M., Reiss P., The long-term consequences of antiretroviral therapy: a review Journal of HIV Therapy 2006 11 2 26 35
    • (2006) Journal of HIV Therapy , vol.11 , Issue.2 , pp. 26-35
    • Boyd, M.1    Reiss, P.2
  • 9
    • 26844543445 scopus 로고    scopus 로고
    • Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides
    • Dubé M. P., Parker R. A., Tebas P., Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides AIDS 2005 19 16 1807 1818
    • (2005) AIDS , vol.19 , Issue.16 , pp. 1807-1818
    • Dubé, M.P.1    Parker, R.A.2    Tebas, P.3
  • 10
    • 33847126560 scopus 로고    scopus 로고
    • Less lipoatrophy and better lipid profile with abacavir as compared to stavudine: 96-week results of a randomized study
    • Podzamczer D., Ferrer E., Sanchez P., Less lipoatrophy and better lipid profile with abacavir as compared to stavudine: 96-week results of a randomized study Journal of Acquired Immune Deficiency Syndromes 2007 44 2 139 147
    • (2007) Journal of Acquired Immune Deficiency Syndromes , vol.44 , Issue.2 , pp. 139-147
    • Podzamczer, D.1    Ferrer, E.2    Sanchez, P.3
  • 11
    • 33645962511 scopus 로고    scopus 로고
    • Pronounced lipoatrophy in HIV-infected men receiving HAART for more than 6 years compared with the background population
    • Hansen A.-B. E., Lindegaard B., Obel N., Andersen O., Nielsen H., Gerstoft J., Pronounced lipoatrophy in HIV-infected men receiving HAART for more than 6 years compared with the background population HIV Medicine 2006 7 1 38 45
    • (2006) HIV Medicine , vol.7 , Issue.1 , pp. 38-45
    • Hansen, A.-B.E.1    Lindegaard, B.2    Obel, N.3    Andersen, O.4    Nielsen, H.5    Gerstoft, J.6
  • 12
    • 33646811534 scopus 로고    scopus 로고
    • Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial
    • Mulligan K., Parker R. A., Komarow L., Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial Journal of Acquired Immune Deficiency Syndromes 2006 41 5 590 597
    • (2006) Journal of Acquired Immune Deficiency Syndromes , vol.41 , Issue.5 , pp. 590-597
    • Mulligan, K.1    Parker, R.A.2    Komarow, L.3
  • 13
    • 34548214568 scopus 로고    scopus 로고
    • High-dose lopinavir/ritonavir in highly treatment-experienced HIV-1 patients: Efficacy, safety, and predictors of response
    • Podzamczer D., King M. S., Klein C. E., High-dose lopinavir/ritonavir in highly treatment-experienced HIV-1 patients: efficacy, safety, and predictors of response HIV Clinical Trials 2007 8 4 193 204
    • (2007) HIV Clinical Trials , vol.8 , Issue.4 , pp. 193-204
    • Podzamczer, D.1    King, M.S.2    Klein, C.E.3
  • 15
    • 0033604038 scopus 로고    scopus 로고
    • Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy
    • Brinkman K., Smeitink J. A., Romijn J. A., Reiss P., Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy The Lancet 1999 354 9184 1112 1115
    • (1999) The Lancet , vol.354 , Issue.9184 , pp. 1112-1115
    • Brinkman, K.1    Smeitink, J.A.2    Romijn, J.A.3    Reiss, P.4
  • 16
    • 0242363266 scopus 로고    scopus 로고
    • Mitochondrial toxicity of NRTI antiviral drugs: An integrated cellular perspective
    • Lewis W., Day B. J., Copeland W. C., Mitochondrial toxicity of NRTI antiviral drugs: an integrated cellular perspective Nature Reviews Drug Discovery 2003 2 10 812 822
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.10 , pp. 812-822
    • Lewis, W.1    Day, B.J.2    Copeland, W.C.3
  • 17
    • 7744223038 scopus 로고    scopus 로고
    • The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro
    • Caron M., Auclair M., Lagathu C., The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro AIDS 2004 18 16 2127 2136
    • (2004) AIDS , vol.18 , Issue.16 , pp. 2127-2136
    • Caron, M.1    Auclair, M.2    Lagathu, C.3
  • 18
    • 33644516938 scopus 로고    scopus 로고
    • Uridine abrogates the adverse effects of antiretroviral pyrimidine analogues on adipose cell functions
    • Walker U. A., Auclair M., Lebrecht D., Kornprobst M., Capeau J., Caron M., Uridine abrogates the adverse effects of antiretroviral pyrimidine analogues on adipose cell functions Antiviral Therapy 2006 11 1 25 34
    • (2006) Antiviral Therapy , vol.11 , Issue.1 , pp. 25-34
    • Walker, U.A.1    Auclair, M.2    Lebrecht, D.3    Kornprobst, M.4    Capeau, J.5    Caron, M.6
  • 19
    • 42149172274 scopus 로고    scopus 로고
    • Contribution of mitochondrial dysfunction and oxidative stress to cellular premature senescence induced by antiretroviral thymidine analogues
    • Caron M., Auclair M., Vissian A., Vigouroux C., Capeau J., Contribution of mitochondrial dysfunction and oxidative stress to cellular premature senescence induced by antiretroviral thymidine analogues Antiviral Therapy 2008 13 1 27 38
    • (2008) Antiviral Therapy , vol.13 , Issue.1 , pp. 27-38
    • Caron, M.1    Auclair, M.2    Vissian, A.3    Vigouroux, C.4    Capeau, J.5
  • 20
    • 0034731520 scopus 로고    scopus 로고
    • Suppression of preadipocyte differentiation and promotion of adipocyte death by HIV protease inhibitors
    • Dowell P., Flexner C., Kwiterovich P. O., Lane M. D., Suppression of preadipocyte differentiation and promotion of adipocyte death by HIV protease inhibitors The Journal of Biological Chemistry 2000 275 52 41325 41332
    • (2000) The Journal of Biological Chemistry , vol.275 , Issue.52 , pp. 41325-41332
    • Dowell, P.1    Flexner, C.2    Kwiterovich, P.O.3    Lane, M.D.4
  • 21
    • 0034987343 scopus 로고    scopus 로고
    • The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistance
    • Caron M., Auclair M., Vigouroux C., Glorian M., Forest C., Capeau J., The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistance Diabetes 2001 50 6 1378 1388
    • (2001) Diabetes , vol.50 , Issue.6 , pp. 1378-1388
    • Caron, M.1    Auclair, M.2    Vigouroux, C.3    Glorian, M.4    Forest, C.5    Capeau, J.6
  • 22
    • 1042263432 scopus 로고    scopus 로고
    • Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation
    • Caron M., Auclair M., Sterlingot H., Kornprobst M., Capeau J., Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation AIDS 2003 17 17 2437 2444
    • (2003) AIDS , vol.17 , Issue.17 , pp. 2437-2444
    • Caron, M.1    Auclair, M.2    Sterlingot, H.3    Kornprobst, M.4    Capeau, J.5
  • 23
    • 11144268546 scopus 로고    scopus 로고
    • Antiretroviral drugs with adverse effects on adipocyte lipid metabolism and survival alter the expression and secretion of proinflammatory cytokines and adiponectin in vitro
    • Lagathu C., Bastard J.-P., Auclair M., Antiretroviral drugs with adverse effects on adipocyte lipid metabolism and survival alter the expression and secretion of proinflammatory cytokines and adiponectin in vitro Antiviral Therapy 2004 9 6 911 920
    • (2004) Antiviral Therapy , vol.9 , Issue.6 , pp. 911-920
    • Lagathu, C.1    Bastard, J.-P.2    Auclair, M.3
  • 24
    • 12544256168 scopus 로고    scopus 로고
    • Human immunodeficiency virus protease inhibitors accumulate into cultured human adipocytes and alter expression of adipocytokines
    • Vernochet C., Azoulay S., Duval D., Human immunodeficiency virus protease inhibitors accumulate into cultured human adipocytes and alter expression of adipocytokines The Journal of Biological Chemistry 2005 280 3 2238 2243
    • (2005) The Journal of Biological Chemistry , vol.280 , Issue.3 , pp. 2238-2243
    • Vernochet, C.1    Azoulay, S.2    Duval, D.3
  • 25
    • 33748071105 scopus 로고    scopus 로고
    • Microarray analysis during adipogenesis identifies new genes altered by antiretroviral drugs
    • Pacenti M., Barzon L., Favaretto F., Microarray analysis during adipogenesis identifies new genes altered by antiretroviral drugs AIDS 2006 20 13 1691 1705
    • (2006) AIDS , vol.20 , Issue.13 , pp. 1691-1705
    • Pacenti, M.1    Barzon, L.2    Favaretto, F.3
  • 26
    • 34848842840 scopus 로고    scopus 로고
    • Mitochondrial toxicity of indinavir, stavudine and zidovudine involves multiple cellular targets in white and brown adipocytes
    • Viengchareun S., Caron M., Auclair M., Mitochondrial toxicity of indinavir, stavudine and zidovudine involves multiple cellular targets in white and brown adipocytes Antiviral Therapy 2007 12 6 919 929
    • (2007) Antiviral Therapy , vol.12 , Issue.6 , pp. 919-929
    • Viengchareun, S.1    Caron, M.2    Auclair, M.3
  • 27
    • 0037415059 scopus 로고    scopus 로고
    • Agent and cell-type specificity in the induction of insulin resistance by HIV protease inhibitors
    • Ben-Romano R., Rudich A., Török D., Agent and cell-type specificity in the induction of insulin resistance by HIV protease inhibitors AIDS 2003 17 1 23 32
    • (2003) AIDS , vol.17 , Issue.1 , pp. 23-32
    • Ben-Romano, R.1    Rudich, A.2    Török, D.3
  • 28
    • 13244265683 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance, lipodystrophy and atherosclerosis induced by HIV protease inhibitors
    • Rudich A., Ben-Romano R., Etzion S., Bashan N., Cellular mechanisms of insulin resistance, lipodystrophy and atherosclerosis induced by HIV protease inhibitors Acta Physiologica Scandinavica 2005 183 1 75 88
    • (2005) Acta Physiologica Scandinavica , vol.183 , Issue.1 , pp. 75-88
    • Rudich, A.1    Ben-Romano, R.2    Etzion, S.3    Bashan, N.4
  • 29
    • 0042438992 scopus 로고    scopus 로고
    • Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophy
    • Domingo P., Matias-Guiu X., Pujol R. M., Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophy AIDS 1999 13 16 2261 2267
    • (1999) AIDS , vol.13 , Issue.16 , pp. 2261-2267
    • Domingo, P.1    Matias-Guiu, X.2    Pujol, R.M.3
  • 31
    • 14544281531 scopus 로고    scopus 로고
    • HIV antiretroviral treatment alters adipokine expression and insulin sensitivity of adipose tissue in vitro and in vivo
    • Lagathu C., Kim M., Maachi M., HIV antiretroviral treatment alters adipokine expression and insulin sensitivity of adipose tissue in vitro and in vivo Biochimie 2005 87 1 65 71
    • (2005) Biochimie , vol.87 , Issue.1 , pp. 65-71
    • Lagathu, C.1    Kim, M.2    Maachi, M.3
  • 32
    • 22844452653 scopus 로고    scopus 로고
    • Altered adipokine response in murine 3T3-F442A adipocytes treated with protease inhibitors and nucleoside reverse transcriptase inhibitors
    • Jones S. P., Janneh O., Back D. J., Pirmohamed M., Altered adipokine response in murine 3T3-F442A adipocytes treated with protease inhibitors and nucleoside reverse transcriptase inhibitors Antiviral Therapy 2005 10 2 207 213
    • (2005) Antiviral Therapy , vol.10 , Issue.2 , pp. 207-213
    • Jones, S.P.1    Janneh, O.2    Back, D.J.3    Pirmohamed, M.4
  • 33
    • 34447289419 scopus 로고    scopus 로고
    • Some HIV antiretrovirals increase oxidative stress and alter chemokine, cytokine or adiponectin production in human adipocytes and macrophages
    • Lagathu C., Eustace B., Prot M., Some HIV antiretrovirals increase oxidative stress and alter chemokine, cytokine or adiponectin production in human adipocytes and macrophages Antiviral Therapy 2007 12 4 489 500
    • (2007) Antiviral Therapy , vol.12 , Issue.4 , pp. 489-500
    • Lagathu, C.1    Eustace, B.2    Prot, M.3
  • 34
    • 34548713556 scopus 로고    scopus 로고
    • Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin a accumulation, oxidative stress and premature cellular senescence
    • Caron M., Auclair M., Donadille B., Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence Cell Death and Differentiation 2007 14 10 1759 1767
    • (2007) Cell Death and Differentiation , vol.14 , Issue.10 , pp. 1759-1767
    • Caron, M.1    Auclair, M.2    Donadille, B.3
  • 35
    • 33845628546 scopus 로고    scopus 로고
    • Nelfinavir induces adipocyte insulin resistance through the induction of oxidative stress: Differential protective effect of antioxidant agents
    • Ben-Romano R., Rudich A., Etzion S., Nelfinavir induces adipocyte insulin resistance through the induction of oxidative stress: differential protective effect of antioxidant agents Antiviral Therapy 2006 11 8 1051 1060
    • (2006) Antiviral Therapy , vol.11 , Issue.8 , pp. 1051-1060
    • Ben-Romano, R.1    Rudich, A.2    Etzion, S.3
  • 36
    • 0037161026 scopus 로고    scopus 로고
    • Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance
    • Bastard J.-P., Caron M., Vidal H., Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance The Lancet 2002 359 9311 1026 1031
    • (2002) The Lancet , vol.359 , Issue.9311 , pp. 1026-1031
    • Bastard, J.-P.1    Caron, M.2    Vidal, H.3
  • 37
    • 4344656133 scopus 로고    scopus 로고
    • Altered fat differentiation and adipocytokine expression are inter-related and linked to morphological changes and insulin resistance in HIV-1-infected lipodystrophic patients
    • Jan V., Cervera P., Maachi M., Altered fat differentiation and adipocytokine expression are inter-related and linked to morphological changes and insulin resistance in HIV-1-infected lipodystrophic patients Antiviral Therapy 2004 9 4 555 564
    • (2004) Antiviral Therapy , vol.9 , Issue.4 , pp. 555-564
    • Jan, V.1    Cervera, P.2    Maachi, M.3
  • 38
    • 0037999080 scopus 로고    scopus 로고
    • Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy
    • Nolan D., Hammond E., Martin A., Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy AIDS 2003 17 9 1329 1338
    • (2003) AIDS , vol.17 , Issue.9 , pp. 1329-1338
    • Nolan, D.1    Hammond, E.2    Martin, A.3
  • 39
    • 14744306492 scopus 로고    scopus 로고
    • Increased adipocyte apoptosis in lipoatrophy improves within 48 weeks of switching patient therapy from stavudine to abacavir or zidovudine
    • Cherry C. L., Lal L., Thompson K. A., Increased adipocyte apoptosis in lipoatrophy improves within 48 weeks of switching patient therapy from stavudine to abacavir or zidovudine Journal of Acquired Immune Deficiency Syndromes 2005 38 3 263 267
    • (2005) Journal of Acquired Immune Deficiency Syndromes , vol.38 , Issue.3 , pp. 263-267
    • Cherry, C.L.1    Lal, L.2    Thompson, K.A.3
  • 40
    • 28944434904 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha in fat redistribution syndromes associated with combination antiretroviral therapy in HIV-1-infected patients: Potential role in subcutaneous adipocyte apoptosis
    • Domingo P., Vidal F., Domingo J. C., Tumour necrosis factor alpha in fat redistribution syndromes associated with combination antiretroviral therapy in HIV-1-infected patients: potential role in subcutaneous adipocyte apoptosis European Journal of Clinical Investigation 2005 35 12 771 780
    • (2005) European Journal of Clinical Investigation , vol.35 , Issue.12 , pp. 771-780
    • Domingo, P.1    Vidal, F.2    Domingo, J.C.3
  • 41
    • 14844282050 scopus 로고    scopus 로고
    • Regulation of PPAR γ activity during adipogenesis
    • supplement 1
    • Farmer S. R., Regulation of PPAR γ activity during adipogenesis International Journal of Obesity 2005 29 supplement 1 S13 S16
    • (2005) International Journal of Obesity , vol.29
    • Farmer, S.R.1
  • 42
    • 13744249406 scopus 로고    scopus 로고
    • PPAR γ -mediated insulin sensitization: The importance of fat versus muscle
    • Kintscher U., Law R. E., PPAR γ -mediated insulin sensitization: the importance of fat versus muscle American Journal of Physiology 2005 288 2 E287 E291
    • (2005) American Journal of Physiology , vol.288 , Issue.2
    • Kintscher, U.1    Law, R.E.2
  • 43
    • 34247636362 scopus 로고    scopus 로고
    • PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism
    • Medina-Gomez G., Gray S. L., Yetukuri L., PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism PLoS Genetics 2007 3 4 e64
    • (2007) PLoS Genetics , vol.3 , Issue.4 , pp. 64
    • Medina-Gomez, G.1    Gray, S.L.2    Yetukuri, L.3
  • 44
    • 13944274395 scopus 로고    scopus 로고
    • PPAR γ as a metabolic regulator: Insights from genomics and pharmacology
    • Savage D. B., PPAR γ as a metabolic regulator: insights from genomics and pharmacology Expert Reviews in Molecular Medicine 2005 7 1 1 16
    • (2005) Expert Reviews in Molecular Medicine , vol.7 , Issue.1 , pp. 1-16
    • Savage, D.B.1
  • 46
    • 33745511931 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications
    • Touyz R. M., Schiffrin E. L., Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications Vascular Pharmacology 2006 45 1 19 28
    • (2006) Vascular Pharmacology , vol.45 , Issue.1 , pp. 19-28
    • Touyz, R.M.1    Schiffrin, E.L.2
  • 49
    • 44149120984 scopus 로고    scopus 로고
    • Molecular determinants of brown adipocyte formation and function
    • Farmer S. R., Molecular determinants of brown adipocyte formation and function Genes & Development 2008 22 10 1269 1275
    • (2008) Genes & Development , vol.22 , Issue.10 , pp. 1269-1275
    • Farmer, S.R.1
  • 50
    • 34347354309 scopus 로고    scopus 로고
    • Macrophage-specific PPAR γ controls alternative activation and improves insulin resistance
    • Odegaard J. I., Ricardo-Gonzalez R. R., Goforth M. H., Macrophage-specific PPAR γ controls alternative activation and improves insulin resistance Nature 2007 447 7148 1116 1120
    • (2007) Nature , vol.447 , Issue.7148 , pp. 1116-1120
    • Odegaard, J.I.1    Ricardo-Gonzalez, R.R.2    Goforth, M.H.3
  • 52
    • 10744222119 scopus 로고    scopus 로고
    • Plasticity of human adipose lineage cells toward endothelial cells: Physiological and therapeutic perspectives
    • Planat-Benard V., Silvestre J.-S., Cousin B., Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives Circulation 2004 109 5 656 663
    • (2004) Circulation , vol.109 , Issue.5 , pp. 656-663
    • Planat-Benard, V.1    Silvestre, J.-S.2    Cousin, B.3
  • 53
    • 4344563444 scopus 로고    scopus 로고
    • Genetic variation in PPARG encoding peroxisome proliferator-activated receptor γ associated with carotid atherosclerosis
    • Al-Shali K. Z., House A. A., Hanley A. J. G., Khan H. M. R., Harris S. B., Genetic variation in PPARG encoding peroxisome proliferator-activated receptor γ associated with carotid atherosclerosis Stroke 2004 35 9 2036 2040
    • (2004) Stroke , vol.35 , Issue.9 , pp. 2036-2040
    • Al-Shali, K.Z.1    House, A.A.2    Hanley, A.J.G.3    Khan, H.M.R.4    Harris, S.B.5
  • 54
    • 29244484585 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: How their effects on macrophages can lead to the development of a new drug therapy against atherosclerosis
    • Li A. C., Palinski W., Peroxisome proliferator-activated receptors: how their effects on macrophages can lead to the development of a new drug therapy against atherosclerosis Annual Review of Pharmacology and Toxicology 2006 46 1 39
    • (2006) Annual Review of Pharmacology and Toxicology , vol.46 , pp. 1-39
    • Li, A.C.1    Palinski, W.2
  • 55
    • 33847350685 scopus 로고    scopus 로고
    • Hypotension, lipodystrophy, and insulin resistance in generalized PPAR γ -deficient mice rescued from embryonic lethality
    • Duan S. Z., Ivashchenko C. Y., Whitesall S. E., Hypotension, lipodystrophy, and insulin resistance in generalized PPAR γ -deficient mice rescued from embryonic lethality The Journal of Clinical Investigation 2007 117 3 812 822
    • (2007) The Journal of Clinical Investigation , vol.117 , Issue.3 , pp. 812-822
    • Duan, S.Z.1    Ivashchenko, C.Y.2    Whitesall, S.E.3
  • 58
    • 32144442169 scopus 로고    scopus 로고
    • Nuclear lamin a inhibits adipocyte differentiation: Implications for Dunnigan-type familial partial lipodystrophy
    • Boguslavsky R. L., Stewart C. L., Worman H. J., Nuclear lamin A inhibits adipocyte differentiation: implications for Dunnigan-type familial partial lipodystrophy Human Molecular Genetics 2006 15 4 653 663
    • (2006) Human Molecular Genetics , vol.15 , Issue.4 , pp. 653-663
    • Boguslavsky, R.L.1    Stewart, C.L.2    Worman, H.J.3
  • 59
    • 20444449733 scopus 로고    scopus 로고
    • Altered pre-lamin a processing is a common mechanism leading to lipodystrophy
    • Capanni C., Mattioli E., Columbaro M., Altered pre-lamin A processing is a common mechanism leading to lipodystrophy Human Molecular Genetics 2005 14 11 1489 1502
    • (2005) Human Molecular Genetics , vol.14 , Issue.11 , pp. 1489-1502
    • Capanni, C.1    Mattioli, E.2    Columbaro, M.3
  • 60
    • 50949112676 scopus 로고    scopus 로고
    • The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation
    • Payne V. A., Grimsey N., Tuthill A., The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation Diabetes 2008 57 8 2055 2060
    • (2008) Diabetes , vol.57 , Issue.8 , pp. 2055-2060
    • Payne, V.A.1    Grimsey, N.2    Tuthill, A.3
  • 62
    • 0035692720 scopus 로고    scopus 로고
    • Synergistic antiadipogenic effects of HIV type 1 protease inhibitors with tumor necrosis factor α: sssuppression of extracellular insulin action mediated by extracellular matrix-degrading proteases
    • Mondal D., Larussa V. F., Agrawal K. C., Synergistic antiadipogenic effects of HIV type 1 protease inhibitors with tumor necrosis factor α: suppression of extracellular insulin action mediated by extracellular matrix-degrading proteases AIDS Research and Human Retroviruses 2001 17 17 1569 1584
    • (2001) AIDS Research and Human Retroviruses , vol.17 , Issue.17 , pp. 1569-1584
    • Mondal, D.1    Larussa, V.F.2    Agrawal, K.C.3
  • 63
    • 0037016425 scopus 로고    scopus 로고
    • Effects of antiretroviral drug combinations on the differentiation of adipocytes
    • Roche R., Poizot-Martin I., Yazidi C. M.-E., Effects of antiretroviral drug combinations on the differentiation of adipocytes AIDS 2002 16 1 13 20
    • (2002) AIDS , vol.16 , Issue.1 , pp. 13-20
    • Roche, R.1    Poizot-Martin, I.2    Yazidi, C.M.-E.3
  • 64
    • 0242364719 scopus 로고    scopus 로고
    • Differential effect of HIV protease inhibitors on adipogenesis: Intracellular ritonavir is not sufficient to inhibit differentiation
    • Vernochet C., Azoulay S., Duval D., Guedj R., Ailhaud G., Dani C., Differential effect of HIV protease inhibitors on adipogenesis: intracellular ritonavir is not sufficient to inhibit differentiation AIDS 2003 17 15 2177 2180
    • (2003) AIDS , vol.17 , Issue.15 , pp. 2177-2180
    • Vernochet, C.1    Azoulay, S.2    Duval, D.3    Guedj, R.4    Ailhaud, G.5    Dani, C.6
  • 65
    • 11144259274 scopus 로고    scopus 로고
    • C/EBP α reverses the anti-adipogenic effects of the HIV protease inhibitor nelfinavir
    • Dowell P., Lane M. D., C/EBP α reverses the anti-adipogenic effects of the HIV protease inhibitor nelfinavir Biochemical and Biophysical Research Communications 2005 327 2 571 574
    • (2005) Biochemical and Biophysical Research Communications , vol.327 , Issue.2 , pp. 571-574
    • Dowell, P.1    Lane, M.D.2
  • 66
    • 27144475596 scopus 로고    scopus 로고
    • HIV protease inhibitors block adipocyte differentiation independently of lamin A/C
    • Kudlow B. A., Jameson S. A., Kennedy B. K., HIV protease inhibitors block adipocyte differentiation independently of lamin A/C AIDS 2005 19 15 1565 1573
    • (2005) AIDS , vol.19 , Issue.15 , pp. 1565-1573
    • Kudlow, B.A.1    Jameson, S.A.2    Kennedy, B.K.3
  • 67
    • 33846891112 scopus 로고    scopus 로고
    • HIV protease inhibitor-specific alterations in human adipocyte differentiation and metabolism
    • Kim R. J., Wilson C. G., Wabitsch M., Lazar M. A., Steppan C. M., HIV protease inhibitor-specific alterations in human adipocyte differentiation and metabolism Obesity 2006 14 6 994 1002
    • (2006) Obesity , vol.14 , Issue.6 , pp. 994-1002
    • Kim, R.J.1    Wilson, C.G.2    Wabitsch, M.3    Lazar, M.A.4    Steppan, C.M.5
  • 68
    • 27744510950 scopus 로고    scopus 로고
    • The effect of the HIV protease inhibitor ritonavir on proliferation, differentiation, lipogenesis, gene expression and apoptosis of human preadipocytes and adipocytes
    • Grigem S., Fischer-Posovszky P., Debatin K. M., Loizon E., Vidal H., Wabitsch M., The effect of the HIV protease inhibitor ritonavir on proliferation, differentiation, lipogenesis, gene expression and apoptosis of human preadipocytes and adipocytes Hormone and Metabolic Research 2005 37 10 602 609
    • (2005) Hormone and Metabolic Research , vol.37 , Issue.10 , pp. 602-609
    • Grigem, S.1    Fischer-Posovszky, P.2    Debatin, K.M.3    Loizon, E.4    Vidal, H.5    Wabitsch, M.6
  • 69
    • 33748510777 scopus 로고    scopus 로고
    • Effects of atazanavir/ritonavir and lopinavir/ritonavir on glucose uptake and insulin sensitivity: Demonstrable differences in vitro and clinically
    • Noor M. A., Flint O. P., Maa J.-F., Parker R. A., Effects of atazanavir/ritonavir and lopinavir/ritonavir on glucose uptake and insulin sensitivity: demonstrable differences in vitro and clinically AIDS 2006 20 14 1813 1821
    • (2006) AIDS , vol.20 , Issue.14 , pp. 1813-1821
    • Noor, M.A.1    Flint, O.P.2    Maa, J.-F.3    Parker, R.A.4
  • 70
    • 40449141143 scopus 로고    scopus 로고
    • HIV-protease inhibitors induce expression of suppressor of cytokine signaling-1 in insulin-sensitive tissues and promote insulin resistance and type 2 diabetes mellitus
    • Carper M. J., Cade W. T., Cam M., HIV-protease inhibitors induce expression of suppressor of cytokine signaling-1 in insulin-sensitive tissues and promote insulin resistance and type 2 diabetes mellitus American Journal of Physiology 2008 294 3 E558 E567
    • (2008) American Journal of Physiology , vol.294 , Issue.3
    • Carper, M.J.1    Cade, W.T.2    Cam, M.3
  • 71
    • 33845897434 scopus 로고    scopus 로고
    • Inhibition of human preadipocyte proteasomal activity by HIV protease inhibitors or specific inhibitor lactacystin leads to a defect in adipogenesis, which involves matrix metalloproteinase-9
    • De Barros S., Zakaroff-Girard A., Lafontan M., Galitzky J., Bourlier V., Inhibition of human preadipocyte proteasomal activity by HIV protease inhibitors or specific inhibitor lactacystin leads to a defect in adipogenesis, which involves matrix metalloproteinase-9 Journal of Pharmacology and Experimental Therapeutics 2007 320 1 291 299
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.320 , Issue.1 , pp. 291-299
    • De Barros, S.1    Zakaroff-Girard, A.2    Lafontan, M.3    Galitzky, J.4    Bourlier, V.5
  • 73
    • 0034617191 scopus 로고    scopus 로고
    • The mechanism of insulin resistance caused by HIV protease inhibitor therapy
    • Murata H., Hruz P. W., Mueckler M., The mechanism of insulin resistance caused by HIV protease inhibitor therapy The Journal of Biological Chemistry 2000 275 27 20251 20254
    • (2000) The Journal of Biological Chemistry , vol.275 , Issue.27 , pp. 20251-20254
    • Murata, H.1    Hruz, P.W.2    Mueckler, M.3
  • 74
    • 3142713042 scopus 로고    scopus 로고
    • Nelfinavir-induced insulin resistance is associated with impaired plasma membrane recruitment of the PI 3-kinase effectors Akt/PKB and PKC- ζ
    • Ben-Romano R., Rudich A., Tirosh A., Nelfinavir-induced insulin resistance is associated with impaired plasma membrane recruitment of the PI 3-kinase effectors Akt/PKB and PKC- ζ Diabetologia 2004 47 6 1107 1117
    • (2004) Diabetologia , vol.47 , Issue.6 , pp. 1107-1117
    • Ben-Romano, R.1    Rudich, A.2    Tirosh, A.3
  • 75
    • 33750825285 scopus 로고    scopus 로고
    • Molecular activation of PPAR γ by angiotensin II type 1-receptor antagonists
    • Erbe D. V., Gartrell K., Zhang Y.-L., Molecular activation of PPAR γ by angiotensin II type 1-receptor antagonists Vascular Pharmacology 2006 45 3 154 162
    • (2006) Vascular Pharmacology , vol.45 , Issue.3 , pp. 154-162
    • Erbe, D.V.1    Gartrell, K.2    Zhang, Y.-L.3
  • 76
    • 7744229686 scopus 로고    scopus 로고
    • The effects of HIV protease inhibitors atazanavir and lopinavir/ritonavir on insulin sensitivity in HIV-seronegative healthy adults
    • Noor M. A., Parker R. A., O'Mara E., The effects of HIV protease inhibitors atazanavir and lopinavir/ritonavir on insulin sensitivity in HIV-seronegative healthy adults AIDS 2004 18 16 2137 2144
    • (2004) AIDS , vol.18 , Issue.16 , pp. 2137-2144
    • Noor, M.A.1    Parker, R.A.2    O'Mara, E.3
  • 77
    • 24044478158 scopus 로고    scopus 로고
    • Low density lipoprotein apolipoprotein B metabolism in treatment-naive HIV patients and patients on antiretroviral therapy
    • Umpleby A. M., Das S., Stolinski M., Low density lipoprotein apolipoprotein B metabolism in treatment-naive HIV patients and patients on antiretroviral therapy Antiviral Therapy 2005 10 5 663 670
    • (2005) Antiviral Therapy , vol.10 , Issue.5 , pp. 663-670
    • Umpleby, A.M.1    Das, S.2    Stolinski, M.3
  • 79
    • 0036537888 scopus 로고    scopus 로고
    • A novel interaction between lamin a and SREBP1: Implications for partial lipodystrophy and other laminopathies
    • Lloyd D. J., Trembath R. C., Shackleton S., A novel interaction between lamin A and SREBP1: implications for partial lipodystrophy and other laminopathies Human Molecular Genetics 2002 11 7 769 777
    • (2002) Human Molecular Genetics , vol.11 , Issue.7 , pp. 769-777
    • Lloyd, D.J.1    Trembath, R.C.2    Shackleton, S.3
  • 80
    • 0033823256 scopus 로고    scopus 로고
    • Lessons from lipodystrophy: LMNA, encoding lamin A/C, in HIV therapy-associated lipodystrophy
    • Behrens G. M. N., Lloyd D., Schmidt H. H.-J., Schmidt R. E., Trembath R. C., Lessons from lipodystrophy: LMNA, encoding lamin A/C, in HIV therapy-associated lipodystrophy AIDS 2000 14 12 1854 1855
    • (2000) AIDS , vol.14 , Issue.12 , pp. 1854-1855
    • Behrens, G.M.N.1    Lloyd, D.2    Schmidt, H.H.-J.3    Schmidt, R.E.4    Trembath, R.C.5
  • 81
    • 33645507099 scopus 로고    scopus 로고
    • In combination, nucleoside reverse transcriptase inhibitors have significant effects on 3T3-L1 adipocyte lipid accumulation and survival
    • Kosmiski L. A., Miller H. L., Klemm D. J., In combination, nucleoside reverse transcriptase inhibitors have significant effects on 3T3-L1 adipocyte lipid accumulation and survival Antiviral Therapy 2006 11 2 187 195
    • (2006) Antiviral Therapy , vol.11 , Issue.2 , pp. 187-195
    • Kosmiski, L.A.1    Miller, H.L.2    Klemm, D.J.3
  • 82
    • 34147136152 scopus 로고    scopus 로고
    • Relationship of mitochondrial DNA depletion and respiratory chain activity in preadipocytes treated with nucleoside reverse transcriptase inhibitors
    • Stankov M. V., Lücke T., Das A. M., Schmidt R. E., Behrens G. M. N., Relationship of mitochondrial DNA depletion and respiratory chain activity in preadipocytes treated with nucleoside reverse transcriptase inhibitors Antiviral Therapy 2007 12 2 205 216
    • (2007) Antiviral Therapy , vol.12 , Issue.2 , pp. 205-216
    • Stankov, M.V.1    Lücke, T.2    Das, A.M.3    Schmidt, R.E.4    Behrens, G.M.N.5
  • 83
    • 14844328611 scopus 로고    scopus 로고
    • Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1- α
    • supplement 1
    • Puigserver P., Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1- α International Journal of Obesity 2005 29 supplement 1 5 9
    • (2005) International Journal of Obesity , vol.29 , pp. 5-9
    • Puigserver, P.1
  • 84
    • 53049085274 scopus 로고    scopus 로고
    • PGC-1 α integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscle
    • Pagel-Langenickel I., Bao J., Joseph J. J., PGC-1 α integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscle The Journal of Biological Chemistry 2008 283 33 22464 22472
    • (2008) The Journal of Biological Chemistry , vol.283 , Issue.33 , pp. 22464-22472
    • Pagel-Langenickel, I.1    Bao, J.2    Joseph, J.J.3
  • 85
    • 2442593038 scopus 로고    scopus 로고
    • In vitro suppression of the lipogenic pathway by the nonnucleoside reverse transcriptase inhibitor efavirenz in 3T3 and human preadipocytes or adipocytes
    • El Hadri K., Glorian M., Monsempes C., In vitro suppression of the lipogenic pathway by the nonnucleoside reverse transcriptase inhibitor efavirenz in 3T3 and human preadipocytes or adipocytes The Journal of Biological Chemistry 2004 279 15 15130 15141
    • (2004) The Journal of Biological Chemistry , vol.279 , Issue.15 , pp. 15130-15141
    • El Hadri, K.1    Glorian, M.2    Monsempes, C.3
  • 86
    • 0035813195 scopus 로고    scopus 로고
    • HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleus
    • Riddle T. M., Kuhel D. G., Woollett L. A., Fichtenbaum C. J., Hui D. Y., HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleus The Journal of Biological Chemistry 2001 276 40 37514 37519
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.40 , pp. 37514-37519
    • Riddle, T.M.1    Kuhel, D.G.2    Woollett, L.A.3    Fichtenbaum, C.J.4    Hui, D.Y.5
  • 87
    • 33644828770 scopus 로고    scopus 로고
    • Ritonavir impairs lipoprotein lipase-mediated lipolysis and decreases uptake of fatty acids in adipose tissue
    • den Boer M. A. M., Berbée J. F. P., Reiss P., Ritonavir impairs lipoprotein lipase-mediated lipolysis and decreases uptake of fatty acids in adipose tissue Arteriosclerosis, Thrombosis, and Vascular Biology 2006 26 1 124 129
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.1 , pp. 124-129
    • Den Boer, M.A.M.1    Berbée, J.F.P.2    Reiss, P.3
  • 88
    • 0346101500 scopus 로고    scopus 로고
    • HIV protease inhibitor ritonavir induces lipoatrophy in male mice
    • Goetzman E. S., Tian L., Nagy T. R., HIV protease inhibitor ritonavir induces lipoatrophy in male mice AIDS Research and Human Retroviruses 2003 19 12 1141 1150
    • (2003) AIDS Research and Human Retroviruses , vol.19 , Issue.12 , pp. 1141-1150
    • Goetzman, E.S.1    Tian, L.2    Nagy, T.R.3
  • 89
    • 33845243670 scopus 로고    scopus 로고
    • Long-term treatment with lopinavir-ritonavir induces a reduction in peripheral adipose depots in mice
    • Prot M., Heripret L., Cardot-Leccia N., Long-term treatment with lopinavir-ritonavir induces a reduction in peripheral adipose depots in mice Antimicrobial Agents and Chemotherapy 2006 50 12 3998 4004
    • (2006) Antimicrobial Agents and Chemotherapy , vol.50 , Issue.12 , pp. 3998-4004
    • Prot, M.1    Heripret, L.2    Cardot-Leccia, N.3
  • 90
    • 20844435624 scopus 로고    scopus 로고
    • In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA
    • Mallon P. W. G., Unemori P., Sedwell R., In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA Journal of Infectious Diseases 2005 191 10 1686 1696
    • (2005) Journal of Infectious Diseases , vol.191 , Issue.10 , pp. 1686-1696
    • Mallon, P.W.G.1    Unemori, P.2    Sedwell, R.3
  • 91
    • 0042732970 scopus 로고    scopus 로고
    • Expression of adipogenic transcription factors, peroxisome proliferator-activated receptor gamma co-activator 1, IL-6 and CD45 in subcutaneous adipose tissue in lipodystrophy associated with highly active antiretroviral therapy
    • Kannisto K., Sutinen J., Korsheninnikova E., Expression of adipogenic transcription factors, peroxisome proliferator-activated receptor gamma co-activator 1, IL-6 and CD45 in subcutaneous adipose tissue in lipodystrophy associated with highly active antiretroviral therapy AIDS 2003 17 12 1753 1762
    • (2003) AIDS , vol.17 , Issue.12 , pp. 1753-1762
    • Kannisto, K.1    Sutinen, J.2    Korsheninnikova, E.3
  • 92
    • 27944487106 scopus 로고    scopus 로고
    • Assessment of adipokine expression and mitochondrial toxicity in HIV patients with lipoatrophy on stavudine-and zidovudine-containing regimens
    • Jones S. P., Qazi N., Morelese J., Assessment of adipokine expression and mitochondrial toxicity in HIV patients with lipoatrophy on stavudine-and zidovudine-containing regimens Journal of Acquired Immune Deficiency Syndromes 2005 40 5 565 572
    • (2005) Journal of Acquired Immune Deficiency Syndromes , vol.40 , Issue.5 , pp. 565-572
    • Jones, S.P.1    Qazi, N.2    Morelese, J.3
  • 93
    • 0042410593 scopus 로고    scopus 로고
    • Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients
    • Pace C. S., Martin A. M., Hammond E. L., Mamotte C. D., Nolan D. A., Mallal S. A., Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients Antiviral Therapy 2003 8 4 323 331
    • (2003) Antiviral Therapy , vol.8 , Issue.4 , pp. 323-331
    • Pace, C.S.1    Martin, A.M.2    Hammond, E.L.3    Mamotte, C.D.4    Nolan, D.A.5    Mallal, S.A.6
  • 94
    • 20944447671 scopus 로고    scopus 로고
    • Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy
    • Chaparro J., Reeds D. N., Wen W., Alterations in thigh subcutaneous adipose tissue gene expression in protease inhibitor-based highly active antiretroviral therapy Metabolism 2005 54 5 561 567
    • (2005) Metabolism , vol.54 , Issue.5 , pp. 561-567
    • Chaparro, J.1    Reeds, D.N.2    Wen, W.3
  • 95
    • 38049072577 scopus 로고    scopus 로고
    • A 6-month interruption of antiretroviral therapy improves adipose tissue function in HIV-infected patients: The ANRS EP29 Lipostop Study
    • Kim M. J., Leclercq P., Lanoy E., A 6-month interruption of antiretroviral therapy improves adipose tissue function in HIV-infected patients: the ANRS EP29 Lipostop Study Antiviral Therapy 2007 12 8 1273 1283
    • (2007) Antiviral Therapy , vol.12 , Issue.8 , pp. 1273-1283
    • Kim, M.J.1    Leclercq, P.2    Lanoy, E.3
  • 96
    • 0042869786 scopus 로고    scopus 로고
    • Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy
    • Vigouroux C., Maachi M., Nguyen T.-H., Serum adipocytokines are related to lipodystrophy and metabolic disorders in HIV-infected men under antiretroviral therapy AIDS 2003 17 10 1503 1511
    • (2003) AIDS , vol.17 , Issue.10 , pp. 1503-1511
    • Vigouroux, C.1    Maachi, M.2    Nguyen, T.-H.3
  • 97
    • 2442641811 scopus 로고    scopus 로고
    • Effects of rosiglitazone on gene expression in subcutaneous adipose tissue in highly active antiretroviral therapy-associated lipodystrophy
    • Sutinen J., Kannisto K., Korsheninnikova E., Effects of rosiglitazone on gene expression in subcutaneous adipose tissue in highly active antiretroviral therapy-associated lipodystrophy American Journal of Physiology 2004 286 6 E941 E949
    • (2004) American Journal of Physiology , vol.286 , Issue.6
    • Sutinen, J.1    Kannisto, K.2    Korsheninnikova, E.3
  • 98
    • 42149084966 scopus 로고    scopus 로고
    • Effect of pioglitazone on HIV-1-related lipodystrophy: A randomized double-blind placebo-controlled trial (ANRS 113)
    • Slama L., Lanoy E., Valantin M.-A., Effect of pioglitazone on HIV-1-related lipodystrophy: a randomized double-blind placebo-controlled trial (ANRS 113) Antiviral Therapy 2008 13 1 67 76
    • (2008) Antiviral Therapy , vol.13 , Issue.1 , pp. 67-76
    • Slama, L.1    Lanoy, E.2    Valantin, M.-A.3
  • 99
    • 43149105759 scopus 로고    scopus 로고
    • Differential gene expression indicates that 'buffalo hump' is a distinct adipose tissue disturbance in HIV-1-associated lipodystrophy
    • Guallar J. P., Gallego-Escuredo J. M., Domingo J. C., Differential gene expression indicates that 'buffalo hump' is a distinct adipose tissue disturbance in HIV-1-associated lipodystrophy AIDS 2008 22 5 575 584
    • (2008) AIDS , vol.22 , Issue.5 , pp. 575-584
    • Guallar, J.P.1    Gallego-Escuredo, J.M.2    Domingo, J.C.3
  • 100
    • 23044503686 scopus 로고    scopus 로고
    • Reverse transcriptase inhibitors alter uncoupling protein-1 and mitochondrial biogenesis in brown adipocytes
    • Rodríguez de la Concepción M. L., Yubero P., Domingo J. C., Reverse transcriptase inhibitors alter uncoupling protein-1 and mitochondrial biogenesis in brown adipocytes Antiviral Therapy 2005 10 4 515 526
    • (2005) Antiviral Therapy , vol.10 , Issue.4 , pp. 515-526
    • Rodríguez De La Concepción, M.L.1    Yubero, P.2    Domingo, J.C.3
  • 101
  • 102
    • 47149096915 scopus 로고    scopus 로고
    • Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity
    • Heilbronn L. K., Campbell L. V., Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity Current Pharmaceutical Design 2008 14 12 1225 1230
    • (2008) Current Pharmaceutical Design , vol.14 , Issue.12 , pp. 1225-1230
    • Heilbronn, L.K.1    Campbell, L.V.2
  • 103
    • 0037312029 scopus 로고    scopus 로고
    • HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages
    • Dressman J., Kincer J., Matveev S. V., HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by increasing CD36-dependent cholesteryl ester accumulation in macrophages The Journal of Clinical Investigation 2003 111 3 389 397
    • (2003) The Journal of Clinical Investigation , vol.111 , Issue.3 , pp. 389-397
    • Dressman, J.1    Kincer, J.2    Matveev, S.V.3


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