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Volumn 37, Issue 1, 2013, Pages 1-7

Impact of Altered Methylation in Cytokine Signaling and Proteasome Function in Alcohol and Viral-Mediated Diseases

Author keywords

Alcohol; Cytokine; Methylation; Viral

Indexed keywords

BETAINE; CYCLIC AMP; CYTOCHROME P450 2E1; CYTOKINE; HISTONE; INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PHOSPHODIESTERASE IV; PROTEASOME; S ADENOSYLMETHIONINE; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84871964152     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2012.01840.x     Document Type: Review
Times cited : (11)

References (57)
  • 1
    • 65649102188 scopus 로고    scopus 로고
    • Nuclear effects of ethanol-induced proteasome inhibition in liver cells
    • Bardag-Gorce F (2009) Nuclear effects of ethanol-induced proteasome inhibition in liver cells. World J Gastroenterol 15:1163-1167.
    • (2009) World J Gastroenterol , vol.15 , pp. 1163-1167
    • Bardag-Gorce, F.1
  • 2
    • 77950809233 scopus 로고    scopus 로고
    • Effects of ethanol on the proteasome interacting proteins
    • Bardag-Gorce F (2010) Effects of ethanol on the proteasome interacting proteins. World J Gastroenterol 16:1349-1357.
    • (2010) World J Gastroenterol , vol.16 , pp. 1349-1357
    • Bardag-Gorce, F.1
  • 3
    • 79957801753 scopus 로고    scopus 로고
    • Proteasome inhibitor treatment in alcoholic liver disease
    • Bardag-Gorce F (2011) Proteasome inhibitor treatment in alcoholic liver disease. World J Gastroenterol 17:5.
    • (2011) World J Gastroenterol , vol.17 , pp. 5
    • Bardag-Gorce, F.1
  • 4
    • 34548213726 scopus 로고    scopus 로고
    • Mallory body formation is associated with epigenetic phenotypic change in hepatocytes in vivo
    • Bardag-Gorce F, Dedes J, French BA, Oliva JV, Li J, French SW (2007) Mallory body formation is associated with epigenetic phenotypic change in hepatocytes in vivo. Exp Mol Pathol 83:160-168.
    • (2007) Exp Mol Pathol , vol.83 , pp. 160-168
    • Bardag-Gorce, F.1    Dedes, J.2    French, B.A.3    Oliva, J.V.4    Li, J.5    French, S.W.6
  • 5
    • 33750505407 scopus 로고    scopus 로고
    • CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation
    • Bardag-Gorce F, French BA, Nan L, Song H, Nguyen SK, Yong H, Dede J, French SW (2006) CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation. Exp Mol Pathol 81:191-201.
    • (2006) Exp Mol Pathol , vol.81 , pp. 191-201
    • Bardag-Gorce, F.1    French, B.A.2    Nan, L.3    Song, H.4    Nguyen, S.K.5    Yong, H.6    Dede, J.7    French, S.W.8
  • 6
    • 77952554640 scopus 로고    scopus 로고
    • SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model
    • Bardag-Gorce F, Oliva J, Li J, French BA, French SW (2010) SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model. Exp Mol Pathol 88:353-362.
    • (2010) Exp Mol Pathol , vol.88 , pp. 353-362
    • Bardag-Gorce, F.1    Oliva, J.2    Li, J.3    French, B.A.4    French, S.W.5
  • 7
    • 78650710068 scopus 로고    scopus 로고
    • Proteasome inhibition up regulates liver antioxidant enzymes in a rat model of alcoholic liver disease
    • Bardag-Gorce F, Oliva J, Lin A, Li J, French BA, French SW (2011) Proteasome inhibition up regulates liver antioxidant enzymes in a rat model of alcoholic liver disease. Exp Mol Pathol 90:123-130.
    • (2011) Exp Mol Pathol , vol.90 , pp. 123-130
    • Bardag-Gorce, F.1    Oliva, J.2    Lin, A.3    Li, J.4    French, B.A.5    French, S.W.6
  • 9
    • 0017282816 scopus 로고
    • Left ventricular angiocardiography in coronary artery disease
    • Bjork L (1976) Left ventricular angiocardiography in coronary artery disease. Radiologe 16:105-109.
    • (1976) Radiologe , vol.16 , pp. 105-109
    • Bjork, L.1
  • 10
    • 0002705479 scopus 로고    scopus 로고
    • S-adenosylmethionine-dependent methyltransferases
    • Carmel R, Jacobsen DW eds), Cambridge University Press, Cambridge.
    • Clarke S, Banfield K (2001) S-adenosylmethionine-dependent methyltransferases, in Homocysteine in Health and Disease (Carmel R, Jacobsen DW eds), pp 63-78. Cambridge University Press, Cambridge.
    • (2001) Homocysteine in Health and Disease , pp. 63-78
    • Clarke, S.1    Banfield, K.2
  • 11
    • 34447265905 scopus 로고    scopus 로고
    • Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling
    • Conti M, Beavo J (2007) Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Annu Rev Biochem 76:481-511.
    • (2007) Annu Rev Biochem , vol.76 , pp. 481-511
    • Conti, M.1    Beavo, J.2
  • 12
    • 27544457323 scopus 로고    scopus 로고
    • Recombinant Hep G2 cells that express alcohol dehydrogenase and cytochrome P450 2E1 as a model of ethanol-elicited cytotoxicity
    • Donohue TM, Osna NA, Clemens DL (2006) Recombinant Hep G2 cells that express alcohol dehydrogenase and cytochrome P450 2E1 as a model of ethanol-elicited cytotoxicity. Int J Biochem Cell Biol 38:92-101.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 92-101
    • Donohue, T.M.1    Osna, N.A.2    Clemens, D.L.3
  • 15
    • 84871941740 scopus 로고    scopus 로고
    • Ethanol induced proteasome inhibition is associated with changes in methylation: effect of S-adenosylmethionine
    • Abstract S230.
    • French SW, Oliva J, Li J, French BA, Bardag-Gorce F (2010) Ethanol induced proteasome inhibition is associated with changes in methylation: effect of S-adenosylmethionine. Alcohol Clin Exp Res 34:73A, Abstract S230.
    • (2010) Alcohol Clin Exp Res , vol.34
    • French, S.W.1    Oliva, J.2    Li, J.3    French, B.A.4    Bardag-Gorce, F.5
  • 17
    • 57349120536 scopus 로고    scopus 로고
    • Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease
    • Gobejishvili L, Barve S, Joshi-Barve S, McClain C (2008) Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease. Am J Physiol Gastrointest Liver Physiol 295:G718-G724.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.295
    • Gobejishvili, L.1    Barve, S.2    Joshi-Barve, S.3    McClain, C.4
  • 18
    • 33749447720 scopus 로고    scopus 로고
    • Chronic ethanol-mediated decrease in cAMP primes macrophages to enhanced LPS-inducible NF-kappaB activity and TNF expression: relevance to alcoholic liver disease
    • Gobejishvili L, Barve S, Joshi-Barve S, Uriarte S, Song Z, McClain C (2006) Chronic ethanol-mediated decrease in cAMP primes macrophages to enhanced LPS-inducible NF-kappaB activity and TNF expression: relevance to alcoholic liver disease. Am J Physiol Gastrointest Liver Physiol 291:G681-G688.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.291
    • Gobejishvili, L.1    Barve, S.2    Joshi-Barve, S.3    Uriarte, S.4    Song, Z.5    McClain, C.6
  • 20
    • 75749117558 scopus 로고    scopus 로고
    • Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown
    • Houslay MD (2010) Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown. Trends Biochem Sci 35:91-100.
    • (2010) Trends Biochem Sci , vol.35 , pp. 91-100
    • Houslay, M.D.1
  • 21
    • 70349335528 scopus 로고    scopus 로고
    • Mechanisms of transcriptional repression by histone lysne methylation
    • Hublitz P, Albert M, Peters AH (2009) Mechanisms of transcriptional repression by histone lysne methylation. Int J Dev Biol 53:335-354.
    • (2009) Int J Dev Biol , vol.53 , pp. 335-354
    • Hublitz, P.1    Albert, M.2    Peters, A.H.3
  • 22
    • 0037188511 scopus 로고    scopus 로고
    • Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-alpha responses
    • Jin SL, Conti M (2002) Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-alpha responses. Proc Natl Acad Sci U S A 99:7628-7633.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 7628-7633
    • Jin, S.L.1    Conti, M.2
  • 23
    • 22544470866 scopus 로고    scopus 로고
    • Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages
    • Jin SL, Lan L, Zoudilova M, Conti M (2005) Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages. J Immunol 175:1523-1531.
    • (2005) J Immunol , vol.175 , pp. 1523-1531
    • Jin, S.L.1    Lan, L.2    Zoudilova, M.3    Conti, M.4
  • 24
    • 67649980707 scopus 로고    scopus 로고
    • Alcoholic liver disease and methionine metabolism
    • Kharbanda KK (2009) Alcoholic liver disease and methionine metabolism. Semin Liver Dis 29:155-165.
    • (2009) Semin Liver Dis , vol.29 , pp. 155-165
    • Kharbanda, K.K.1
  • 25
    • 34247562178 scopus 로고    scopus 로고
    • Defects in methionine metabolism: Its role in ethanol-induced liver injury
    • Preedy VR, Watson RR eds), Elsevier Academic Press, San Diego, CA.
    • Kharbanda KK, Barak AJ (2005) Defects in methionine metabolism: Its role in ethanol-induced liver injury, in Comprehensive Handbook of Alcohol-Related Pathology, Vol 2 (Preedy VR, Watson RR eds), pp 735-747. Elsevier Academic Press, San Diego, CA.
    • (2005) Comprehensive Handbook of Alcohol-Related Pathology , vol.2 , pp. 735-747
    • Kharbanda, K.K.1    Barak, A.J.2
  • 26
    • 34347327136 scopus 로고    scopus 로고
    • Proteasome activity modulates chromatin modifications and RNA polymerase II phosphorylation to enhance glucocorticoid receptor-mediated transcription
    • Kinyamu HK, Archer TK (2007) Proteasome activity modulates chromatin modifications and RNA polymerase II phosphorylation to enhance glucocorticoid receptor-mediated transcription. Mol Cell Biol 27:4891-4904.
    • (2007) Mol Cell Biol , vol.27 , pp. 4891-4904
    • Kinyamu, H.K.1    Archer, T.K.2
  • 27
    • 0036532202 scopus 로고    scopus 로고
    • Histone methylation in transcriptional control
    • Kouzarides T (2002) Histone methylation in transcriptional control. Curr Opin Genet Dev 12:198-209.
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 198-209
    • Kouzarides, T.1
  • 28
    • 39549103864 scopus 로고    scopus 로고
    • S-adenosylmethionine prevents Mallory Denk body formation in drug-primed mice by inhibiting the epigenetic memory
    • Li J, Bardag-Gorce F, Dedes J, French BA, Amidi F, Oliva J, French SW (2008) S-adenosylmethionine prevents Mallory Denk body formation in drug-primed mice by inhibiting the epigenetic memory. Hepatology 47:613-624.
    • (2008) Hepatology , vol.47 , pp. 613-624
    • Li, J.1    Bardag-Gorce, F.2    Dedes, J.3    French, B.A.4    Amidi, F.5    Oliva, J.6    French, S.W.7
  • 30
    • 0024587645 scopus 로고
    • Increased tumor necrosis factor production by monocytes in alcoholic hepatitis
    • McClain CJ, Cohen DA (1989) Increased tumor necrosis factor production by monocytes in alcoholic hepatitis. Hepatology 9:349-351.
    • (1989) Hepatology , vol.9 , pp. 349-351
    • McClain, C.J.1    Cohen, D.A.2
  • 33
    • 0027453813 scopus 로고
    • Immunohistochemical detection of tumor necrosis factor-alpha, other cytokines and adhesion molecules in human livers with alcoholic hepatitis
    • Ohlinger W, Dinges HP, Zatloukal K, Mair S, Gollowitsch F, Denk H (1993) Immunohistochemical detection of tumor necrosis factor-alpha, other cytokines and adhesion molecules in human livers with alcoholic hepatitis. Virchows Arch A Pathol Anat Histopathol 423:169-176.
    • (1993) Virchows Arch A Pathol Anat Histopathol , vol.423 , pp. 169-176
    • Ohlinger, W.1    Dinges, H.P.2    Zatloukal, K.3    Mair, S.4    Gollowitsch, F.5    Denk, H.6
  • 35
    • 77954032981 scopus 로고    scopus 로고
    • The role of cytokines in UbD promoter regulation and Mallory-Denk body-like aggresomes
    • Oliva J, Bardag-Gorce F, Lin A, French BA, French SW (2010a) The role of cytokines in UbD promoter regulation and Mallory-Denk body-like aggresomes. Exp Mol Pathol 89:1-8.
    • (2010) Exp Mol Pathol , vol.89 , pp. 1-8
    • Oliva, J.1    Bardag-Gorce, F.2    Lin, A.3    French, B.A.4    French, S.W.5
  • 36
    • 65649100057 scopus 로고    scopus 로고
    • Epigenetics of proteasome inhibition in the liver of rats fed ethanol chronically
    • Oliva J, Dedes J, Li J, French SW, Bardag-Gorce F (2009b) Epigenetics of proteasome inhibition in the liver of rats fed ethanol chronically. World J Gastroenterol 15:705-712.
    • (2009) World J Gastroenterol , vol.15 , pp. 705-712
    • Oliva, J.1    Dedes, J.2    Li, J.3    French, S.W.4    Bardag-Gorce, F.5
  • 37
    • 84871952536 scopus 로고    scopus 로고
    • Proteasome inhibitor treatment reduces hepatic steatosis by decreasing lipogenic enzyme gene expression
    • Abstract #308.
    • Oliva J, Lin A, Li J, French BA, French SW, Bardag-Gorce F (2010b) Proteasome inhibitor treatment reduces hepatic steatosis by decreasing lipogenic enzyme gene expression. Alcohol Clin Exp Res 34:87A, Abstract #308.
    • (2010) Alcohol Clin Exp Res , vol.34
    • Oliva, J.1    Lin, A.2    Li, J.3    French, B.A.4    French, S.W.5    Bardag-Gorce, F.6
  • 38
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002: new surprises in the Jak/Stat pathway
    • O'Shea JJ, Gadina M, Schreiber RD (2002) Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell 109(Suppl):S121-S131.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • O'Shea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 39
    • 30944453568 scopus 로고    scopus 로고
    • Ethanol metabolism alters interferon gamma signaling in recombinant HepG2 cells
    • Osna NA, Clemens DL, Donohue TM Jr (2005) Ethanol metabolism alters interferon gamma signaling in recombinant HepG2 cells. Hepatology 42:1109-1117.
    • (2005) Hepatology , vol.42 , pp. 1109-1117
    • Osna, N.A.1    Clemens, D.L.2    Donohue Jr., T.M.3
  • 40
    • 34848860810 scopus 로고    scopus 로고
    • Implication of altered proteasome function in alcoholic liver injury
    • Osna NA, Donohue TM Jr (2007) Implication of altered proteasome function in alcoholic liver injury. World J Gastroenterol 13:4931-4937.
    • (2007) World J Gastroenterol , vol.13 , pp. 4931-4937
    • Osna, N.A.1    Donohue Jr., T.M.2
  • 41
    • 67649934683 scopus 로고    scopus 로고
    • Ethanol and hepatitis C viral proteins regulate interferon signaling in liver cells via impaired methylation of STAT1
    • Osna N, Donohue T, White R, Beard M, Kharbanda K (2008) Ethanol and hepatitis C viral proteins regulate interferon signaling in liver cells via impaired methylation of STAT1. Hepatology 48:75A.
    • (2008) Hepatology , vol.48
    • Osna, N.1    Donohue, T.2    White, R.3    Beard, M.4    Kharbanda, K.5
  • 43
    • 65449181938 scopus 로고    scopus 로고
    • Ethanol metabolism alters major histocompatibility complex class I-restricted antigen presentation in liver cells
    • Osna NA, White RL, Thiele GM, Donohue TM Jr (2009) Ethanol metabolism alters major histocompatibility complex class I-restricted antigen presentation in liver cells. Hepatology 49:1308-1315.
    • (2009) Hepatology , vol.49 , pp. 1308-1315
    • Osna, N.A.1    White, R.L.2    Thiele, G.M.3    Donohue Jr., T.M.4
  • 44
    • 33846333917 scopus 로고    scopus 로고
    • Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine
    • Ou X, Yang H, Ramani K, Ara AI, Chen H, Mato JM, Lu SC (2007) Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine. Biochem J 401:87-96.
    • (2007) Biochem J , vol.401 , pp. 87-96
    • Ou, X.1    Yang, H.2    Ramani, K.3    Ara, A.I.4    Chen, H.5    Mato, J.M.6    Lu, S.C.7
  • 45
    • 34548527262 scopus 로고    scopus 로고
    • Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes
    • Pal-Bhadra M, Bhadra U, Jackson DE, Mamatha L, Park PH, Shukla SD (2007) Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes. Life Sci 81:979-987.
    • (2007) Life Sci , vol.81 , pp. 979-987
    • Pal-Bhadra, M.1    Bhadra, U.2    Jackson, D.E.3    Mamatha, L.4    Park, P.H.5    Shukla, S.D.6
  • 47
    • 33749394256 scopus 로고    scopus 로고
    • Epigenetic effects of ethanol on liver and gastrointestinal injury
    • Shukla SD, Aroor AR (2006) Epigenetic effects of ethanol on liver and gastrointestinal injury. World J Gastroenterol 12:5265-5271.
    • (2006) World J Gastroenterol , vol.12 , pp. 5265-5271
    • Shukla, S.D.1    Aroor, A.R.2
  • 49
    • 17444400829 scopus 로고    scopus 로고
    • S-adenosylmethionine (SAMe) modulates interleukin-10 and interleukin-6, but not TNF, production via the adenosine (A2) receptor
    • Song Z, Uriarte S, Sahoo R, Chen T, Barve S, Hill D, McClain C (2005) S-adenosylmethionine (SAMe) modulates interleukin-10 and interleukin-6, but not TNF, production via the adenosine (A2) receptor. Biochim Biophys Acta 1743:205-213.
    • (2005) Biochim Biophys Acta , vol.1743 , pp. 205-213
    • Song, Z.1    Uriarte, S.2    Sahoo, R.3    Chen, T.4    Barve, S.5    Hill, D.6    McClain, C.7
  • 50
  • 51
    • 33845645536 scopus 로고    scopus 로고
    • The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells
    • Szutorisz H, Georgiou A, Tora L, Dillon N (2006) The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells. Cell 127:1375-1388.
    • (2006) Cell , vol.127 , pp. 1375-1388
    • Szutorisz, H.1    Georgiou, A.2    Tora, L.3    Dillon, N.4
  • 52
    • 3242671568 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5′-methylthioadenosine
    • Veal N, Hsieh CL, Xiong S, Mato JM, Lu S, Tsukamoto H (2004) Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5′-methylthioadenosine. Am J Physiol Gastrointest Liver Physiol 287:G352-G362.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287
    • Veal, N.1    Hsieh, C.L.2    Xiong, S.3    Mato, J.M.4    Lu, S.5    Tsukamoto, H.6
  • 53
    • 37849038662 scopus 로고    scopus 로고
    • Combination of oxidative stress and steatosis is a risk factor for fibrosis in alcohol-drinking patients with chronic hepatitis C
    • Vidali M, Occhino G, Ivaldi A, Rigamonti C, Sartori M, Albano E (2008) Combination of oxidative stress and steatosis is a risk factor for fibrosis in alcohol-drinking patients with chronic hepatitis C. Am J Gastroenterol 103:147-153.
    • (2008) Am J Gastroenterol , vol.103 , pp. 147-153
    • Vidali, M.1    Occhino, G.2    Ivaldi, A.3    Rigamonti, C.4    Sartori, M.5    Albano, E.6
  • 54
    • 0141992115 scopus 로고    scopus 로고
    • mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression
    • Wang H, An W, Cao R, Xia L, Erdjument-Bromage H, Chatton B, Tempst P, Roeder RG, Zhang Y (2003) mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression. Mol Cell 12:475-487.
    • (2003) Mol Cell , vol.12 , pp. 475-487
    • Wang, H.1    An, W.2    Cao, R.3    Xia, L.4    Erdjument-Bromage, H.5    Chatton, B.6    Tempst, P.7    Roeder, R.G.8    Zhang, Y.9
  • 55
    • 0033567294 scopus 로고    scopus 로고
    • S-adenosylmethionine attenuates the lipopolysaccharide-induced expression of the gene for tumour necrosis factor alpha
    • Watson WH, Zhao Y, Chawla RK (1999) S-adenosylmethionine attenuates the lipopolysaccharide-induced expression of the gene for tumour necrosis factor alpha. Biochem J 342:21-25.
    • (1999) Biochem J , vol.342 , pp. 21-25
    • Watson, W.H.1    Zhao, Y.2    Chawla, R.K.3
  • 56
    • 37449013810 scopus 로고    scopus 로고
    • Expression pattern, regulation, and functions of methionine adenosyltransferase 2beta splicing variants in hepatoma cells
    • Yang H, Ara AI, Magilnick N, Xia M, Ramani K, Chen H, Lee TD, Mato JM, Lu SC (2008) Expression pattern, regulation, and functions of methionine adenosyltransferase 2beta splicing variants in hepatoma cells. Gastroenterology 134:281-291.
    • (2008) Gastroenterology , vol.134 , pp. 281-291
    • Yang, H.1    Ara, A.I.2    Magilnick, N.3    Xia, M.4    Ramani, K.5    Chen, H.6    Lee, T.D.7    Mato, J.M.8    Lu, S.C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.