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Volumn 33, Issue 2, 2013, Pages 281-292

Novel role for SHP-2 in nutrient-responsive control of S6 kinase 1 signaling

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; INOSITOL 1,4,5 TRISPHOSPHATE; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE C; PHOSPHOLIPASE C BETA4; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE SHP 2; S6 KINASE; S6 KINASE 1; SERINE; THREONINE; UNCLASSIFIED DRUG;

EID: 84871901272     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01285-12.     Document Type: Article
Times cited : (21)

References (66)
  • 1
    • 84859778293 scopus 로고    scopus 로고
    • mTOR signaling in growth control and disease
    • Laplante M, Sabatini DM. 2012. mTOR signaling in growth control and disease. Cell 149:274-293.
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 2
    • 78649348967 scopus 로고    scopus 로고
    • Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
    • Sengupta S, Peterson TR, Sabatini DM. 2010. Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol. Cell 40:310-322.
    • (2010) Mol. Cell , vol.40 , pp. 310-322
    • Sengupta, S.1    Peterson, T.R.2    Sabatini, D.M.3
  • 3
    • 3342895823 scopus 로고    scopus 로고
    • Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptorindependent pathway that regulates the cytoskeleton
    • Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument- Bromage H, Tempst P, Sabatini DM. 2004. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptorindependent pathway that regulates the cytoskeleton. Curr. Biol. 14: 1296-1302.
    • (2004) Curr. Biol. , vol.14 , pp. 1296-1302
    • Sarbassov, D.D.1    Ali, S.M.2    Kim, D.H.3    Guertin, D.A.4    Latek, R.R.5    Erdjument-bromage, H.6    Tempst, P.7    Sabatini, D.M.8
  • 4
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. 2005. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307:1098-1101.
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 5
    • 67349217986 scopus 로고    scopus 로고
    • Molecular mechanisms of mTOR-mediated translational control
    • Ma XM, Blenis J. 2009. Molecular mechanisms of mTOR-mediated translational control. Nat. Rev. Mol. Cell Biol. 10:307-318.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 307-318
    • Ma, X.M.1    Blenis, J.2
  • 6
    • 13444259647 scopus 로고    scopus 로고
    • Regulation of cap-dependent translation by eIF4E inhibitory proteins
    • Richter JD, Sonenberg N. 2005. Regulation of cap-dependent translation by eIF4E inhibitory proteins. Nature 433:477- 480.
    • (2005) Nature , vol.433
    • Richter, J.D.1    Sonenberg, N.2
  • 7
    • 0043127125 scopus 로고    scopus 로고
    • Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
    • Inoki K, Li Y, Xu T, Guan KL. 2003. Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes Dev. 17:1829- 1834.
    • (2003) Genes Dev. , vol.17
    • Inoki, K.1    Li, Y.2    Xu, T.3    Guan, K.L.4
  • 8
    • 0042701991 scopus 로고    scopus 로고
    • Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
    • Tee AR, Manning BD, Roux PP, Cantley LC, Blenis J. 2003. Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb. Curr. Biol. 13:1259-1268.
    • (2003) Curr. Biol. , vol.13 , pp. 1259-1268
    • Tee, A.R.1    Manning, B.D.2    Roux, P.P.3    Cantley, L.C.4    Blenis, J.5
  • 9
    • 77951768486 scopus 로고    scopus 로고
    • Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
    • Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM. 2010. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell 141:290-303.
    • (2010) Cell , vol.141 , pp. 290-303
    • Sancak, Y.1    Bar-peled, L.2    Zoncu, R.3    Markhard, A.L.4    Nada, S.5    Sabatini, D.M.6
  • 11
    • 25444457577 scopus 로고    scopus 로고
    • hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase
    • Byfield MP, Murray JT, Backer JM. 2005. hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase. J. Biol. Chem. 280: 33076-33082.
    • (2005) J. Biol. Chem. , vol.280 , pp. 33076-33082
    • Byfield, M.P.1    Murray, J.T.2    Backer, J.M.3
  • 13
    • 0031019664 scopus 로고    scopus 로고
    • An intracellular calcium signal activates p70 but not p90 ribosomal S6 kinase in liver epithelial cells
    • Graves LM, He Y, Lambert J, Hunter D, Li X, Earp HS. 1997. An intracellular calcium signal activates p70 but not p90 ribosomal S6 kinase in liver epithelial cells. J. Biol. Chem. 272:1920-1928.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1920-1928
    • Graves, L.M.1    He, Y.2    Lambert, J.3    Hunter, D.4    Li, X.5    Earp, H.S.6
  • 14
    • 0037337449 scopus 로고    scopus 로고
    • Activation of S6K1 (p70 ribosomal protein S6 kinase 1) requires an initial calcium-dependent priming event involving formation of a high-molecular-mass signalling complex
    • Hannan KM, Thomas G, Pearson RB. 2003. Activation of S6K1 (p70 ribosomal protein S6 kinase 1) requires an initial calcium-dependent priming event involving formation of a high-molecular-mass signalling complex. Biochem. J. 370:469-477.
    • (2003) Biochem. J. , vol.370 , pp. 469-477
    • Hannan, K.M.1    Thomas, G.2    Pearson, R.B.3
  • 15
    • 0033604644 scopus 로고    scopus 로고
    • Shp-2 tyrosine phosphatase: signaling one cell or many
    • Feng GS. 1999. Shp-2 tyrosine phosphatase: signaling one cell or many. Exp. Cell Res. 253:47-54.
    • (1999) Exp. Cell Res. , vol.253 , pp. 47-54
    • Feng, G.S.1
  • 16
    • 0038771965 scopus 로고    scopus 로고
    • The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
    • Neel BG, Gu H, Pao L. 2003. The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem. Sci. 28:284-293.
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 284-293
    • Neel, B.G.1    Gu, H.2    Pao, L.3
  • 18
    • 79953698416 scopus 로고    scopus 로고
    • The tyrosine phosphatase Shp-2 interacts with the dopamine D(1) receptor and triggers D(1)-mediated Erk signaling in striatal neurons
    • Fiorentini C, Mattanza C, Collo G, Savoia P, Spano P, Missale C. 2011. The tyrosine phosphatase Shp-2 interacts with the dopamine D(1) receptor and triggers D(1)-mediated Erk signaling in striatal neurons. J. Neurochem. 117:253-263.
    • (2011) J. Neurochem. , vol.117 , pp. 253-263
    • Fiorentini, C.1    Mattanza, C.2    Collo, G.3    Savoia, P.4    Spano, P.5    Missale, C.6
  • 19
    • 0142059890 scopus 로고    scopus 로고
    • Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signaling
    • Agazie YM, Hayman MJ. 2003. Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signaling. Mol. Cell. Biol. 23:7875- 7886.
    • (2003) Mol. Cell. Biol. , vol.23
    • Agazie, Y.M.1    Hayman, M.J.2
  • 20
    • 0032238275 scopus 로고    scopus 로고
    • Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway
    • Cleghon V, Feldmann P, Ghiglione C, Copeland TD, Perrimon N, Hughes DA, Morrison DK. 1998. Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway. Mol. Cell 2:719-727.
    • (1998) Mol. Cell , vol.2 , pp. 719-727
    • Cleghon, V.1    Feldmann, P.2    Ghiglione, C.3    Copeland, T.D.4    Perrimon, N.5    Hughes, D.A.6    Morrison, D.K.7
  • 23
    • 34147142287 scopus 로고    scopus 로고
    • SHP-2 regulates cell growth by controlling the mTOR/S6 kinase 1 pathway
    • Zito CI, Qin H, Blenis J, Bennett AM. 2007. SHP-2 regulates cell growth by controlling the mTOR/S6 kinase 1 pathway. J. Biol. Chem. 282:6946- 6953.
    • (2007) J. Biol. Chem. , vol.282
    • Zito, C.I.1    Qin, H.2    Blenis, J.3    Bennett, A.M.4
  • 24
  • 25
    • 0036091468 scopus 로고    scopus 로고
    • Role of SHP-2 in fibroblast growth factor receptor-mediated suppression of myogenesis in C2C12 myoblasts
    • Kontaridis MI, Liu X, Zhang L, Bennett AM. 2002. Role of SHP-2 in fibroblast growth factor receptor-mediated suppression of myogenesis in C2C12 myoblasts. Mol. Cell. Biol. 22:3875-3891.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3875-3891
    • Kontaridis, M.I.1    Liu, X.2    Zhang, L.3    Bennett, A.M.4
  • 27
    • 0035094978 scopus 로고    scopus 로고
    • Role of leucine in the regulation of mTOR by amino acids: revelations from structure-activity studies
    • Lynch CJ. 2001. Role of leucine in the regulation of mTOR by amino acids: revelations from structure-activity studies. J. Nutr. 131:861S- 865S.
    • (2001) J. Nutr. , vol.131
    • Lynch, C.J.1
  • 29
    • 56249147509 scopus 로고    scopus 로고
    • Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
    • Choo AY, Yoon SO, Kim SG, Roux PP, Blenis J. 2008. Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation. Proc. Natl. Acad. Sci. U. S. A. 105:17414- 17419.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105
    • Choo, A.Y.1    Yoon, S.O.2    Kim, S.G.3    Roux, P.P.4    Blenis, J.5
  • 32
    • 0037191045 scopus 로고    scopus 로고
    • Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide- 3-OH kinase is mTOR independent
    • Jaeschke A, Hartkamp J, Saitoh M, Roworth W, Nobukuni T, Hodges A, Sampson J, Thomas G, Lamb R. 2002. Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide- 3-OH kinase is mTOR independent. J. Cell Biol. 159:217-224.
    • (2002) J. Cell Biol. , vol.159 , pp. 217-224
    • Jaeschke, A.1    Hartkamp, J.2    Saitoh, M.3    Roworth, W.4    Nobukuni, T.5    Hodges, A.6    Sampson, J.7    Thomas, G.8    Lamb, R.9
  • 33
    • 1842525884 scopus 로고    scopus 로고
    • SHP-2 regulates the phosphatidylinositide 3=-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis
    • Ivins Zito C, Kontaridis MI, Fornaro M, Feng GS, Bennett AM. 2004. SHP-2 regulates the phosphatidylinositide 3=-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis. J. Cell. Physiol. 199:227-236.
    • (2004) J. Cell. Physiol. , vol.199 , pp. 227-236
    • Ivins Zito, C.1    Kontaridis, M.I.2    Fornaro, M.3    Feng, G.S.4    Bennett, A.M.5
  • 34
    • 13544270759 scopus 로고    scopus 로고
    • DOK1 mediates SHP-2 binding to the alphaVbeta3 integrin and thereby regulates insulin-like growth factor I signaling in cultured vascular smooth muscle cells
    • Ling Y, Maile LA, Badley-Clarke J, Clemmons DR. 2005. DOK1 mediates SHP-2 binding to the alphaVbeta3 integrin and thereby regulates insulin-like growth factor I signaling in cultured vascular smooth muscle cells. J. Biol. Chem. 280:3151-3158.
    • (2005) J. Biol. Chem. , vol.280 , pp. 3151-3158
    • Ling, Y.1    Maile, L.A.2    Badley-clarke, J.3    Clemmons, D.R.4
  • 35
    • 0033761488 scopus 로고    scopus 로고
    • The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase
    • Maroun CR, Naujokas MA, Holgado-Madruga M, Wong AJ, Park M. 2000. The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase. Mol. Cell. Biol. 20: 8513-8525.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8513-8525
    • Maroun, C.R.1    Naujokas, M.A.2    Holgado-madruga, M.3    Wong, A.J.4    Park, M.5
  • 36
    • 0037064549 scopus 로고    scopus 로고
    • Role of the SHP-2 tyrosine phosphatase in cytokineinduced signaling and cellular response
    • Qu CK. 2002. Role of the SHP-2 tyrosine phosphatase in cytokineinduced signaling and cellular response. Biochim. Biophys. Acta 1592: 297-301.
    • (2002) Biochim. Biophys. Acta , vol.1592 , pp. 297-301
    • Qu, C.K.1
  • 39
    • 0032548942 scopus 로고    scopus 로고
    • Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k
    • Conus NM, Hemmings BA, Pearson RB. 1998. Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k. J. Biol. Chem. 273:4776-4782.
    • (1998) J. Biol. Chem. , vol.273 , pp. 4776-4782
    • Conus, N.M.1    Hemmings, B.A.2    Pearson, R.B.3
  • 41
    • 37149029370 scopus 로고    scopus 로고
    • Calcium signaling
    • Clapham DE. 2007. Calcium signaling. Cell 131:1047-1058.
    • (2007) Cell , vol.131 , pp. 1047-1058
    • Clapham, D.E.1
  • 42
    • 0026009773 scopus 로고
    • Ryanodine receptor protein is expressed during differentiation in the muscle cell lines BC3H1 and C2C12
    • Airey JA, Baring MD, Sutko JL. 1991. Ryanodine receptor protein is expressed during differentiation in the muscle cell lines BC3H1 and C2C12. Dev. Biol. 148:365-374.
    • (1991) Dev. Biol. , vol.148 , pp. 365-374
    • Airey, J.A.1    Baring, M.D.2    Sutko, J.L.3
  • 45
    • 0028971813 scopus 로고
    • Phosphoinositide-specific phospholipase C and mitogenic signaling
    • Noh DY, Shin SH, Rhee SG. 1995. Phosphoinositide-specific phospholipase C and mitogenic signaling. Biochim. Biophys. Acta 1242:99-113.
    • (1995) Biochim. Biophys. Acta , vol.1242 , pp. 99-113
    • Noh, D.Y.1    Shin, S.H.2    Rhee, S.G.3
  • 46
    • 0028283331 scopus 로고
    • Activation of phospholipase C beta 4 by heterotrimeric GTP-binding proteins
    • Jiang H, Wu D, Simon MI. 1994. Activation of phospholipase C beta 4 by heterotrimeric GTP-binding proteins. J. Biol. Chem. 269:7593-7596.
    • (1994) J. Biol. Chem. , vol.269 , pp. 7593-7596
    • Jiang, H.1    Wu, D.2    Simon, M.I.3
  • 47
    • 0025793981 scopus 로고
    • Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq
    • Smrcka AV, Hepler JR, Brown KO, Sternweis PC. 1991. Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq. Science 251:804-807.
    • (1991) Science , vol.251 , pp. 804-807
    • Smrcka, A.V.1    Hepler, J.R.2    Brown, K.O.3    Sternweis, P.C.4
  • 48
    • 0025860413 scopus 로고
    • Activation of the beta 1 isozyme of phospholipase C by alpha subunits of the Gq class of G proteins
    • Taylor SJ, Chae HZ, Rhee SG, Exton JH. 1991. Activation of the beta 1 isozyme of phospholipase C by alpha subunits of the Gq class of G proteins. Nature 350:516-518.
    • (1991) Nature , vol.350 , pp. 516-518
    • Taylor, S.J.1    Chae, H.Z.2    Rhee, S.G.3    Exton, J.H.4
  • 49
    • 0030936370 scopus 로고    scopus 로고
    • Proteintyrosine phosphatase SHP2 is positively linked to proteinase-activated receptor 2-mediated mitogenic pathway
    • Yu Z, Ahmad S, Schwartz J-L, Banville D, Shen S-H. 1997. Proteintyrosine phosphatase SHP2 is positively linked to proteinase-activated receptor 2-mediated mitogenic pathway. J. Biol. Chem. 272:7519-7524.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7519-7524
    • Yu, Z.1    Ahmad, S.2    Schwartz, J.L.3    Banville, D.4    Shen, S.H.5
  • 51
    • 0028899789 scopus 로고
    • Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
    • Blommaart EF, Luiken JJ, Blommaart PJ, van Woerkom GM, Meijer AJ. 1995. Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes. J. Biol. Chem. 270:2320-2326.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2320-2326
    • Blommaart, E.F.1    Luiken, J.J.2    Blommaart, P.J.3    van Woerkom, G.M.4    Meijer, A.J.5
  • 54
    • 79952104568 scopus 로고    scopus 로고
    • mTOR couples cellular nutrient sensing to organismal metabolic homeostasis
    • Howell JJ, Manning BD. 2011. mTOR couples cellular nutrient sensing to organismal metabolic homeostasis. Trends Endocrinol. Metab. 22:94- 102.
    • (2011) Trends Endocrinol. Metab. , vol.22
    • Howell, J.J.1    Manning, B.D.2
  • 55
    • 79958285227 scopus 로고    scopus 로고
    • PLCbeta1-SHP-2 complex, PLCbeta1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling? J
    • Calo LA, Bordin L, Davis PA, Pagnin E, Dal Maso L, Rossi GP, Pessina AC, Clari G. 2011. PLCbeta1-SHP-2 complex, PLCbeta1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling? J. Biomed. Sci. 18:38.
    • (2011) Biomed. Sci. , vol.18 , pp. 38
    • Calo, L.A.1    Bordin, L.2    Davis, P.A.3    Pagnin, E.4    Dal Maso, L.5    Rossi, G.P.6    Pessina, A.C.7    Clari, G.8
  • 56
    • 61449235398 scopus 로고    scopus 로고
    • Not all substrates are treated equally: implications for mTOR, rapamycin-resistance and cancer therapy
    • Choo AY, Blenis J. 2009. Not all substrates are treated equally: implications for mTOR, rapamycin-resistance and cancer therapy. Cell Cycle 8:567-572.
    • (2009) Cell Cycle , vol.8 , pp. 567-572
    • Choo, A.Y.1    Blenis, J.2
  • 57
    • 0033118334 scopus 로고    scopus 로고
    • Molecular tinkering of G protein-coupled receptors: an evolutionary success
    • Bockaert J, Pin JP. 1999. Molecular tinkering of G protein-coupled receptors: an evolutionary success. EMBO J. 18:1723-1729.
    • (1999) EMBO J. , vol.18 , pp. 1723-1729
    • Bockaert, J.1    Pin, J.P.2
  • 58
    • 77954244300 scopus 로고    scopus 로고
    • Broad-spectrum amino acid-sensing class C G-protein coupled receptors: molecular mechanisms, physiological significance and options for drug development
    • Conigrave AD, Hampson DR. 2010. Broad-spectrum amino acid-sensing class C G-protein coupled receptors: molecular mechanisms, physiological significance and options for drug development. Pharmacol. Ther. 127: 252-260.
    • (2010) Pharmacol. Ther. , vol.127 , pp. 252-260
    • Conigrave, A.D.1    Hampson, D.R.2
  • 60


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