Activation of S6K1 (p70 ribosomal protein S6 kinase 1) requires an initial calcium-dependent priming event involving formation of a high-molecular-mass signalling complex

Biochemical Journal

Volumn 370, Issue 2, 2003, Pages 469-477

  Hannan, Katherine M ^a   Thomas, George ^b   Pearson, Richard B ^a  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

Calcium; Phosphoinositide dependent kinase 1; Phosphorylation; Protein interactions; S6 kinase 1; Signal transduction

Indexed keywords

CALCIUM; CHELATION; COMPLEXATION; HYDROPHOBICITY;

PHOSPHORYLATION REACTIONS;

PROTEINS;

CALCIUM; ISOENZYME; P70 RIBOSOMAL PROTEIN S6 KINASE 1; THREONINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHELATION; CONTROLLED STUDY; EMBRYO; ENZYME REGULATION; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROPHOBICITY; IMMUNOPRECIPITATION; MOLECULAR BIOLOGY; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

CALCIUM; CARRIER PROTEINS; CELL LINE; ENZYME ACTIVATION; HUMANS; MACROMOLECULAR SUBSTANCES; PHOSPHORYLATION; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037337449     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021709     Document Type: Article

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