Mercury modulates the cytochrome P450 1a1, 1a2 and 1b1 in C57BL/6J mice: In vivo and in vitro studies

Toxicology and Applied Pharmacology

Volumn 266, Issue 3, 2013, Pages 419-429

  Amara, Issa E A ^a   Anwar Mohamed, Anwar ^a   Abdelhamid, Ghada ^a   El Kadi, Ayman O S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

AhR; C57BL 6J; Cyp1a1; Cyp1a2; Cyp1b1; Cyp450s; Hepatocyte; Hg2+; HO 1; Mercury; TCDD; XRE

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; ETHOXYRESORUFIN DEETHYLASE; HEME OXYGENASE 1; HEMOGLOBIN; LUCIFERASE; MERCURY; MESSENGER RNA; METHOXYRESORUFIN; RESORUFIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; GENE EXPRESSION REGULATION; HEMOGLOBIN BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; LIVER; LIVER CELL; MALE; MICROSOME; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING;

ANIMALS; BLOTTING, WESTERN; CYTOCHROME P-450 CYP1A1; HEME OXYGENASE-1; HEMOGLOBINS; HEPATOCYTES; LIVER; MALE; MERCURY; METALLOPORPHYRINS; MICE; MICE, INBRED C57BL; REAL-TIME POLYMERASE CHAIN REACTION; RNA; TETRACHLORODIBENZODIOXIN;

MUS;

EID: 84871896421     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.11.027     Document Type: Article

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