Effect of mercury on aryl hydrocarbon receptor-regulated genes in the extrahepatic tissues of C57BL/6 mice

Food and Chemical Toxicology

Volumn 50, Issue 7, 2012, Pages 2325-2334

  Amara, Issa E A ^a   Anwar Mohamed, Anwar ^a   Abdelhamid, Ghada ^a   El Kadi, Ayman O S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Aryl hydrocarbon receptor; Cyp1a1; Gene expression; In vivo; Mercury; Nqo1

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; GLUTATHIONE TRANSFERASE A1; HEME OXYGENASE 1; MERCURY; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE) 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARYL HYDROCARBON RECEPTOR GENE; BIOCATALYSIS; CONTROLLED STUDY; CYTOCHROME P450 1A1 GENE; CYTOCHROME P450 1A2 GENE; CYTOCHROME P450 1B1 GENE; ENZYME ACTIVITY; ENZYME MECHANISM; GENE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE EXPRESSION SYSTEM; GENE INDUCTION; GLUTATHIONE S TRANSFERASE A1 GENE; HEME OXYGENASE 1 GENE; IN VIVO STUDY; MALE; MOUSE; NAD(P)H QUINONE OXIDOREDUCTASE 1 GENE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INDUCTION; RECEPTOR GENE; TOXICITY TESTING;

ANIMALS; BASE SEQUENCE; BIOCATALYSIS; BLOTTING, WESTERN; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; DRUG SYNERGISM; ENZYME INDUCTION; GENE EXPRESSION REGULATION; HEART; KIDNEY; LUNG; MERCURY; MICE; MICE, INBRED C57BL; MYOCARDIUM; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ARYL HYDROCARBON; TETRACHLORODIBENZODIOXIN;

MUS;

EID: 84861449032     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.04.028     Document Type: Article

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