Influence of overexpression of efflux proteins on the function and gene expression of endogenous peptide transporters in MDR-transfected MDCKII cell lines

International Journal of Pharmaceutics

Volumn 441, Issue 1-2, 2013, Pages 40-49

  Wang, Zhiying ^a   Pal, Dhananjay ^a   Patel, Ashaben ^a   Kwatra, Deep ^a   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Efflux pumps; MDCK cells; MDR transfection; Peptide transporters

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; PEPTIDE TRANSPORTER 1; PEPTIDE TRANSPORTER 2; TRITIUM;

ANIMAL CELL; ARTICLE; CELL PH; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG PENETRATION; DRUG TRANSPORT; DRUG UPTAKE; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; IMMUNOBLOTTING; MDCK CELL; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; TEMPERATURE DEPENDENCE; TIGHT JUNCTION; WILD TYPE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; DIPEPTIDES; DOGS; DOWN-REGULATION; GENE EXPRESSION; HUMANS; HYDROGEN-ION CONCENTRATION; MADIN DARBY CANINE KIDNEY CELLS; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; P-GLYCOPROTEIN; REAL-TIME POLYMERASE CHAIN REACTION; SYMPORTERS; TRANSFECTION;

EID: 84871871771     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.12.011     Document Type: Article

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