TRIF modulates TLR5-dependent responses by inducing proteolytic degradation of TLR5

Journal of Biological Chemistry

Volumn 285, Issue 28, 2010, Pages 21382-21390

  Choi, Yoon Jeong ^a   Im, Eunok ^a   Pothoulakis, Charalabos ^a   Rhee, Sang Hoon ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR MOLECULE; CASPASE INHIBITORS; CASPASES; CATHEPSIN B; CELLULAR EVENTS; CELLULAR LEVELS; CELLULAR PROTEINS; EPITHELIAL CELLS; EXTRACELLULAR DOMAINS; HEK-293; HUMAN EMBRYONIC KIDNEYS; INFLAMMATORY RESPONSE; MRNA LEVEL; OVER-EXPRESSION; PATTERN RECOGNITION RECEPTORS; PROTEASOMES; PROTEIN DEGRADATION; PROTEOLYTIC DEGRADATION; REACTIVE OXYGEN SPECIES; SPECIFIC INHIBITORS; UBIQUITIN;

KETONES; MOLECULES; OXYGEN; PATTERN RECOGNITION; PROTEINS; SIGNALING;

DEGRADATION;

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CATHEPSIN B INHIBITOR; FLAGELLIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; PROTEASOME; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; UBIQUITIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; COLON MUCOSA; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIUM CELL; GENE OVEREXPRESSION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CASPASES; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; MICE; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER; TOLL-LIKE RECEPTOR 5;

EID: 77954381441     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.115022     Document Type: Article

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