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Volumn 128, Issue 6 SUPPL., 2005, Pages 585S-590S

Transforming growth factor-β signal transduction in angiogenesis and vascular disorders

Author keywords

Angiogenesis; Endothelial cells; Hereditary hemorrhagic telangiectasia; Smad; Transforming growth factor

Indexed keywords

ACTIVIN RECEPTOR; ACTIVIN RECEPTOR LIKE KINASE 1 RECEPTOR; ACTIVIN RECEPTOR LIKE KINASE 5 RECEPTOR; PHOSPHOTRANSFERASE; PROTEIN SERINE THREONINE KINASE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNCLASSIFIED DRUG;

EID: 30144440059     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.128.6_suppl.585S     Document Type: Conference Paper
Times cited : (234)

References (28)
  • 1
    • 0036904895 scopus 로고    scopus 로고
    • Genetic analysis of the mammalian transforming growth factor-β superfamily
    • Chang H, Brown CW, Matzuk MM. Genetic analysis of the mammalian transforming growth factor-β superfamily. Endocr Rev 2002; 23:787-823
    • (2002) Endocr Rev , vol.23 , pp. 787-823
    • Chang, H.1    Brown, C.W.2    Matzuk, M.M.3
  • 2
    • 0141594935 scopus 로고    scopus 로고
    • From developmental disorder to heritable cancer: It's all in the BMP/TGF-β family
    • Waite KA, Eng C. From developmental disorder to heritable cancer: it's all in the BMP/TGF-β family. Nat Rev Genet 2003; 4:763-773
    • (2003) Nat Rev Genet , vol.4 , pp. 763-773
    • Waite, K.A.1    Eng, C.2
  • 3
    • 0141428794 scopus 로고    scopus 로고
    • Controlling the angiogenic switch: A balance between two distinct TGF-β receptor signaling pathways
    • Goumans MJ, Lebrin F, Valdimarsdottir G. Controlling the angiogenic switch: a balance between two distinct TGF-β receptor signaling pathways. Trends Cardiovasc Med 2003; 13:301-307
    • (2003) Trends Cardiovasc Med , vol.13 , pp. 301-307
    • Goumans, M.J.1    Lebrin, F.2    Valdimarsdottir, G.3
  • 4
    • 2342488852 scopus 로고    scopus 로고
    • New insights into TGF-β-Smad signalling
    • ten Dijke P, Hill CS. New insights into TGF-β-Smad signalling. Trends Biochem Sci 2004; 29:265-273
    • (2004) Trends Biochem Sci , vol.29 , pp. 265-273
    • Ten Dijke, P.1    Hill, C.S.2
  • 5
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000; 6:389-395
    • (2000) Nat Med , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 6
    • 0043164827 scopus 로고    scopus 로고
    • Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFβ coreceptor
    • Sorensen LK, Brooke BS, Li DY, et al. Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFβ coreceptor. Dev Biol 2003; 261:235-250
    • (2003) Dev Biol , vol.261 , pp. 235-250
    • Sorensen, L.K.1    Brooke, B.S.2    Li, D.Y.3
  • 7
    • 0027176133 scopus 로고
    • Biphasic effect of transforming growth factor-β 1 on in vitro angiogenesis
    • Pepper MS, Vassalli JD, Orci L, et al. Biphasic effect of transforming growth factor-β 1 on in vitro angiogenesis. Exp Cell Res 1993; 204:356-363
    • (1993) Exp Cell Res , vol.204 , pp. 356-363
    • Pepper, M.S.1    Vassalli, J.D.2    Orci, L.3
  • 8
    • 12944273545 scopus 로고    scopus 로고
    • Activin receptor-like kinase 1 modulates transforming growth factor-β 1 signaling in the regulation of angiogenesis
    • Oh SP, Seki T, Goss KA, et al. Activin receptor-like kinase 1 modulates transforming growth factor-β 1 signaling in the regulation of angiogenesis. Proc Natl Acad Sci U S A 2000; 97:2626-2631
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 2626-2631
    • Oh, S.P.1    Seki, T.2    Goss, K.A.3
  • 9
    • 0242330126 scopus 로고    scopus 로고
    • Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFβ/ALK5 signaling
    • Goumans MJ, Valdimarsdottir G, Itoh S, et al. Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFβ/ALK5 signaling. Mol Cell 2003; 12:817-828
    • (2003) Mol Cell , vol.12 , pp. 817-828
    • Goumans, M.J.1    Valdimarsdottir, G.2    Itoh, S.3
  • 10
    • 0036888627 scopus 로고    scopus 로고
    • Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-β in human umbilical vein endothelial cells
    • Ota T, Fujii M, Sugizaki T, et al. Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-β in human umbilical vein endothelial cells. J Cell Physiol 2002; 193:299-318
    • (2002) J Cell Physiol , vol.193 , pp. 299-318
    • Ota, T.1    Fujii, M.2    Sugizaki, T.3
  • 11
    • 0037007226 scopus 로고    scopus 로고
    • Balancing the activation state of the endothelium via two distinct TGF-β type I receptors
    • Goumans MJ, Valdimarsdottir G, Itoh S, et al. Balancing the activation state of the endothelium via two distinct TGF-β type I receptors. EMBO J 2002; 21:1743-1753
    • (2002) EMBO J , vol.21 , pp. 1743-1753
    • Goumans, M.J.1    Valdimarsdottir, G.2    Itoh, S.3
  • 12
    • 0347363474 scopus 로고    scopus 로고
    • TGF-β receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells
    • Watabe T, Nishihara A, Mishima K, et al. TGF-β receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells. J Cell Biol 2003; 163:1303-1311
    • (2003) J Cell Biol , vol.163 , pp. 1303-1311
    • Watabe, T.1    Nishihara, A.2    Mishima, K.3
  • 13
    • 0037076796 scopus 로고    scopus 로고
    • Mature vascular endothelium can give rise to smooth muscle cells via endothelial-mesenchymal transdifferentiation: In vitro analysis
    • Frid MG, Kale VA, Stenmark KR. Mature vascular endothelium can give rise to smooth muscle cells via endothelial-mesenchymal transdifferentiation: in vitro analysis. Circ Res 2002; 90:1189-1196
    • (2002) Circ Res , vol.90 , pp. 1189-1196
    • Frid, M.G.1    Kale, V.A.2    Stenmark, K.R.3
  • 14
    • 0032847679 scopus 로고    scopus 로고
    • Similarities and differences in smooth muscle a-actin induction by TGF-β in smooth muscle versus non-smooth muscle cells
    • Hautmann MB, Adam PJ, Owens GK. Similarities and differences in smooth muscle a-actin induction by TGF-β in smooth muscle versus non-smooth muscle cells. Arterioscler Thromb Vasc Biol 1999; 19:2049-2058
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2049-2058
    • Hautmann, M.B.1    Adam, P.J.2    Owens, G.K.3
  • 15
    • 0036828120 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-β activity decreases angiogenesis in a human prostate cancer-reactive stroma xenograft model
    • Tuxhorn JA, McAlhany SJ, Yang F, et al. Inhibition of transforming growth factor-β activity decreases angiogenesis in a human prostate cancer-reactive stroma xenograft model. Cancer Res 2002; 62:6021-6025
    • (2002) Cancer Res , vol.62 , pp. 6021-6025
    • Tuxhorn, J.A.1    McAlhany, S.J.2    Yang, F.3
  • 16
    • 0038725471 scopus 로고    scopus 로고
    • CD105 is important for angiogenesis: Evidence and potential applications
    • Duff SE, Li C, Garland JM, et al. CD105 is important for angiogenesis: evidence and potential applications. FASEB J 2003; 17:984-992
    • (2003) FASEB J , vol.17 , pp. 984-992
    • Duff, S.E.1    Li, C.2    Garland, J.M.3
  • 17
    • 0037404842 scopus 로고    scopus 로고
    • Endoglin (CD105): A target for anti-angiogenetic cancer therapy
    • Fonsatti E, Altomonte M, Arslan P, et al. Endoglin (CD105): a target for anti-angiogenetic cancer therapy. Curr Drug Targets 2003; 4:291-296
    • (2003) Curr Drug Targets , vol.4 , pp. 291-296
    • Fonsatti, E.1    Altomonte, M.2    Arslan, P.3
  • 18
    • 0242708765 scopus 로고    scopus 로고
    • Endoglin (CD105): A powerful therapeutic target on tumor-associated angiogenetic blood vessels
    • Fonsatti E, Altomonte M, Nicotra MR, et al. Endoglin (CD105): a powerful therapeutic target on tumor-associated angiogenetic blood vessels. Oncogene 2003; 22:6557-6563
    • (2003) Oncogene , vol.22 , pp. 6557-6563
    • Fonsatti, E.1    Altomonte, M.2    Nicotra, M.R.3
  • 19
    • 12144286738 scopus 로고    scopus 로고
    • A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 (SMAD4)
    • Gallione CJ, Repetto GM, Legius E, et al. A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 (SMAD4). Lancet 2004; 363:852-859
    • (2004) Lancet , vol.363 , pp. 852-859
    • Gallione, C.J.1    Repetto, G.M.2    Legius, E.3
  • 20
    • 0033621804 scopus 로고    scopus 로고
    • Endoglin, an ancillary TGFβ receptor, is required for extraembryonic angiogenesis and plays a key role in heart development
    • Arthur HM, Ure J, Smith AJ, et al. Endoglin, an ancillary TGFβ receptor, is required for extraembryonic angiogenesis and plays a key role in heart development. Dev Biol 2000; 217:42-53
    • (2000) Dev Biol , vol.217 , pp. 42-53
    • Arthur, H.M.1    Ure, J.2    Smith, A.J.3
  • 21
    • 0032720393 scopus 로고    scopus 로고
    • A murine model of hereditary hemorrhagic telangiectasia
    • Bourdeau A, Dumont DJ, Letarte M. A murine model of hereditary hemorrhagic telangiectasia. J Clin Invest 1999; 104:1343-1351
    • (1999) J Clin Invest , vol.104 , pp. 1343-1351
    • Bourdeau, A.1    Dumont, D.J.2    Letarte, M.3
  • 22
    • 0037341510 scopus 로고    scopus 로고
    • A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2
    • Srmivasan S, Hanes MA, Dickens T, et al. A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2. Hum Mol Genet 2003; 12:473-482
    • (2003) Hum Mol Genet , vol.12 , pp. 473-482
    • Srmivasan, S.1    Hanes, M.A.2    Dickens, T.3
  • 23
    • 0033612141 scopus 로고    scopus 로고
    • Defective angiogenesis in mice lacking endoglin
    • Li DY, Sorensen LK, Brooke BS, et al. Defective angiogenesis in mice lacking endoglin. Science 1999; 284:1534-1537
    • (1999) Science , vol.284 , pp. 1534-1537
    • Li, D.Y.1    Sorensen, L.K.2    Brooke, B.S.3
  • 24
    • 0033817459 scopus 로고    scopus 로고
    • Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension: The International PPH Consortium
    • Lane KB, Machado RD, Pauciulo MW, et al. Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension: The International PPH Consortium. Nat Genet 2000; 26:81-84
    • (2000) Nat Genet , vol.26 , pp. 81-84
    • Lane, K.B.1    Machado, R.D.2    Pauciulo, M.W.3
  • 25
    • 0035797556 scopus 로고    scopus 로고
    • Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia
    • Trembath RC, Thomson JR, Machado RD, et al. Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia. N Engl J Med 2001; 345:325-334
    • (2001) N Engl J Med , vol.345 , pp. 325-334
    • Trembath, R.C.1    Thomson, J.R.2    Machado, R.D.3
  • 26
    • 1042266621 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces abnormal microvasculature in the endoglin heterozygous mouse brain
    • Xu B, Wu YQ, Huey M, et al. Vascular endothelial growth factor induces abnormal microvasculature in the endoglin heterozygous mouse brain. J Cereb Blood Flow Metab 2004; 24:237-244
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 237-244
    • Xu, B.1    Wu, Y.Q.2    Huey, M.3
  • 27
    • 4444231521 scopus 로고    scopus 로고
    • Isolation of a regulatory region of activin receptor-like kinase 1 gene sufficient for arterial endothelium-specific expression
    • Seki T, Hong KH, Yun J, et al. Isolation of a regulatory region of activin receptor-like kinase 1 gene sufficient for arterial endothelium-specific expression. Circ Res 2004; 94:e72-77
    • (2004) Circ Res , vol.94
    • Seki, T.1    Hong, K.H.2    Yun, J.3
  • 28
    • 0036517380 scopus 로고    scopus 로고
    • Exogenous application of transforming growth factor β 1 stimulates arteriogenesis in the peripheral circulation
    • van Royen N, Hoefer I, Buschmann I, et al. Exogenous application of transforming growth factor β 1 stimulates arteriogenesis in the peripheral circulation. FASEB J 2002; 16:432-434
    • (2002) FASEB J , vol.16 , pp. 432-434
    • Van Royen, N.1    Hoefer, I.2    Buschmann, I.3


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