-
1
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
DOI 10.1056/NEJMoa065213
-
Larsen, C. M., Faulenbach, M., Vaag, A., Vølund, A., Ehses, J. A., Seifert, B., Mandrup-Poulsen, T., and Donath, M. Y. (2007) Interleukin-1- receptor antagonist in type 2 diabetes mellitus. N. Engl. J. Med. 356, 1517-1526 (Pubitemid 46588416)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.15
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
Volund, A.4
Ehses, J.A.5
Seifert, B.6
Mandrup-Poulsen, T.7
Donath, M.Y.8
-
2
-
-
42449091550
-
The antiinflammatory cytokine interleukin-1 receptor antagonist protects from high-fat diet-induced hyperglycemia
-
DOI 10.1210/en.2007-1059
-
Sauter, N. S., Schulthess, F. T., Galasso, R., Castellani, L. W., and Maedler, K. (2008) The antiinflammatory cytokine interleukin-1 receptor antagonist protects from high-fat diet-induced hyperglycemia. Endocrinology 149, 2208-2218 (Pubitemid 351574505)
-
(2008)
Endocrinology
, vol.149
, Issue.5
, pp. 2208-2218
-
-
Sauter, N.S.1
Schulthess, F.T.2
Galasso, R.3
Castellani, L.W.4
Maedler, K.5
-
3
-
-
58949097266
-
Kupffer cell products and interleukin 1β directly promote VLDL secretion and apoB mRNA up-regulation in rodent hepatocytes
-
Bartolomé, N., Arteta, B., Martínez, M. J., Chico, Y., and Ochoa, B. (2008) Kupffer cell products and interleukin 1β directly promote VLDL secretion and apoB mRNA up-regulation in rodent hepatocytes. Innate Immun. 14, 255-266
-
(2008)
Innate Immun.
, vol.14
, pp. 255-266
-
-
Bartolomé, N.1
Arteta, B.2
Martínez, M.J.3
Chico, Y.4
Ochoa, B.5
-
4
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL- 1 signaling
-
DOI 10.1126/science.278.5343.1612
-
Muzio, M., Ni, J., Feng, P., and Dixit, V. M. (1997) IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 278, 1612-1615 (Pubitemid 27516277)
-
(1997)
Science
, vol.278
, Issue.5343
, pp. 1612-1615
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
5
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
DOI 10.1016/S1074-7613(00)80402-1
-
Wesche, H., Henzel, W. J., Shillinglaw, W., Li, S., and Cao, Z. (1997) MyD88. An adapter that recruits IRAK to the IL-1 receptor complex. Immunity 7, 837-847 (Pubitemid 28064897)
-
(1997)
Immunity
, vol.7
, Issue.6
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.5
-
6
-
-
0033580466
-
The kinase TAK1 can activate the NIK-I κB as well as the MAP kinase cascade in the IL-1 signalling pathway
-
Ninomiya-Tsuji, J., Kishimoto, K., Hiyama, A., Inoue, J., Cao, Z., and Matsumoto, K. (1999) The kinase TAK1 can activate the NIK-I κB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398, 252-256
-
(1999)
Nature
, vol.398
, pp. 252-256
-
-
Ninomiya-Tsuji, J.1
Kishimoto, K.2
Hiyama, A.3
Inoue, J.4
Cao, Z.5
Matsumoto, K.6
-
7
-
-
4444272893
-
Expression of neutral sphingomyelinase-2 (NSMase-2) in primary rat hepatocytes modulates IL-β-induced JNK activation
-
DOI 10.1096/fj.03-0875fje
-
Karakashian, A. A., Giltiay, N. V., Smith, G. M., and Nikolova-Karakashian, M. N. (2004) Expression of neutral sphingomyelinase-2 (nSMase-2) in primary rat hepatocytes modulates IL-β-induced JNK activation. FASEB J. 18, 968-970 (Pubitemid 39561494)
-
(2004)
FASEB Journal
, vol.18
, Issue.9
, pp. 968-970
-
-
Karakashian, A.A.1
Giltiay, N.V.2
Smith, G.M.3
Nikolova-Karakashian, M.N.4
-
8
-
-
27444433461
-
Ceramide- and ERK-dependent pathway for the activation of CCAAT/enhancer binding protein by interleukin-1β in hepatocytes
-
DOI 10.1194/jlr.M500337-JLR200
-
Giltiay, N. V., Karakashian, A. A., Alimov, A. P., Ligthle, S., and Nikolova-Karakashian, M. N. (2005) Ceramide- and ERK-dependent pathway for the activation of CCAAT/enhancer binding protein by interleukin-1β in hepatocytes. J. Lipid Res. 46, 2497-2505 (Pubitemid 41532538)
-
(2005)
Journal of Lipid Research
, vol.46
, Issue.11
, pp. 2497-2505
-
-
Giltiay, N.V.1
Karakashian, A.A.2
Alimov, A.P.3
Ligthle, S.4
Nikolova-Karakashian, M.N.5
-
9
-
-
80052757589
-
Protein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1β
-
Dobierzewska, A., Giltiay, N. V., Sabapathi, S., Karakashian, A. A., and Nikolova-Karakashian, M. N. (2011) Protein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1β. J. Biol. Chem. 286, 32064-32073
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 32064-32073
-
-
Dobierzewska, A.1
Giltiay, N.V.2
Sabapathi, S.3
Karakashian, A.A.4
Nikolova-Karakashian, M.N.5
-
10
-
-
45749133797
-
FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice
-
DOI 10.1172/JCI32914
-
Kamagate, A., Qu, S., Perdomo, G., Su, D., Kim, D. H., Slusher, S., Meseck, M., and Dong, H. H. (2008) FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice. J. Clin. Invest. 118, 2347-2364 (Pubitemid 351872351)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.6
, pp. 2347-2364
-
-
Kamagate, A.1
Qu, S.2
Perdomo, G.3
Su, D.4
Dae, H.K.5
Slusher, S.6
Meseck, M.7
Dong, H.H.8
-
11
-
-
34548349302
-
Impaired Regulation of Hepatic Glucose Production in Mice Lacking the Forkhead Transcription Factor Foxo1 in Liver
-
DOI 10.1016/j.cmet.2007.08.006, PII S1550413107002288
-
Matsumoto, M., Pocai, A., Rossetti, L., Depinho, R. A., and Accili, D. (2007) Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor FoxO1 in liver. Cell Metab 6, 208-216 (Pubitemid 47336849)
-
(2007)
Cell Metabolism
, vol.6
, Issue.3
, pp. 208-216
-
-
Matsumoto, M.1
Pocai, A.2
Rossetti, L.3
DePinho, R.A.4
Accili, D.5
-
12
-
-
79251557845
-
Targeting Forkhead box O1 from the concept to metabolic diseases: Lessons from mouse models
-
Cheng, Z., and White, M. F. (2011) Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models. Antioxid. Redox Signal. 14, 649-661
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 649-661
-
-
Cheng, Z.1
White, M.F.2
-
13
-
-
34548289502
-
Dynamic FoxO transcription factors
-
DOI 10.1242/jcs.001222
-
Huang, H., and Tindall, D. J. (2007) Dynamic FoxO transcription factors. J. Cell Sci. 120, 2479-2487 (Pubitemid 47323857)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.15
, pp. 2479-2487
-
-
Huang, H.1
Tindall, D.J.2
-
14
-
-
27844497945
-
FOXO transcription factors at the interface between longevity and tumor suppression
-
DOI 10.1038/sj.onc.1209086, PII 1209086
-
Greer, E. L., and Brunet, A. (2005) FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24, 7410-7425 (Pubitemid 41637981)
-
(2005)
Oncogene
, vol.24
, Issue.50
, pp. 7410-7425
-
-
Greer, E.L.1
Brunet, A.2
-
15
-
-
33644865024
-
The forkhead transcription factor FoxO1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation
-
Kawamori, D., Kaneto, H., Nakatani, Y., Matsuoka, T. A., Matsuhisa, M., Hori, M., and Yamasaki, Y. (2006) The forkhead transcription factor FoxO1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation. J. Biol. Chem. 281, 1091-1098
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1091-1098
-
-
Kawamori, D.1
Kaneto, H.2
Nakatani, Y.3
Matsuoka, T.A.4
Matsuhisa, M.5
Hori, M.6
Yamasaki, Y.7
-
16
-
-
34848899559
-
ERK2-mediated C-terminal serine phosphorylation of p300 is vital to the regulation of epidermal growth factor-induced keratin 16 gene expression
-
DOI 10.1074/jbc.M700264200
-
Chen, Y.-J., Wang, Y.-N., and Chang, W.-C. (2007) ERK2-mediated C-terminal serine phosphorylation of p300 is vital to the regulation of epidermal growth factor-induced keratin 16 gene expression. J. Biol. Chem. 282, 27215-27228 (Pubitemid 47501975)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.37
, pp. 27215-27228
-
-
Chen, Y.-J.1
Wang, Y.-N.2
Chang, W.-C.3
-
17
-
-
0034462121
-
Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN
-
DOI 10.1128/MCB.20.23.8969-8982.2000
-
Nakamura, N., Ramaswamy, S., Vazquez, F., Signoretti, S., Loda, M., and Sellers, W. R. (2000) Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. Mol. Cell. Biol. 20, 8969-8982 (Pubitemid 32245927)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.23
, pp. 8969-8982
-
-
Nakamura, N.1
Ramaswamy, S.2
Vazquez, F.3
Signoretti, S.4
Loda, M.5
Sellers, W.R.6
-
18
-
-
79957815888
-
P300 acetyltransferase activity differentially regulates the localization and activity of the FOXO homologues in skeletal muscle
-
Senf, S. M., Sandesara, P. B., Reed, S. A., and Judge, A. R. (2011) p300 acetyltransferase activity differentially regulates the localization and activity of the FOXO homologues in skeletal muscle. Am. J. Physiol. Cell Physiol. 300, C1490-C1501
-
(2011)
Am. J. Physiol. Cell Physiol.
, vol.300
-
-
Senf, S.M.1
Sandesara, P.B.2
Reed, S.A.3
Judge, A.R.4
-
19
-
-
0030795329
-
Bimodal regulation of ceramidase by interleukin-1β. Implications for the regulation of cytochrome P450 2C11 (CYP2C11)
-
DOI 10.1074/jbc.272.30.18718
-
Nikolova-Karakashian, M., Morgan, E. T., Alexander, C., Liotta, D. C., and Merrill, A. H., Jr. (1997) Bimodal regulation of ceramidase by interleukin-1β. Implications for the regulation of cytochrome p450 2C11. J. Biol. Chem. 272, 18718-18724 (Pubitemid 27318216)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.30
, pp. 18718-18724
-
-
Nikolova-Karakashian, M.1
Morgan, E.T.2
Alexander, C.3
Liotta, D.C.4
Merrill Jr., A.H.5
-
20
-
-
34547520207
-
Aging in rat causes hepatic hyperresposiveness to interleukin-1β which is mediated by neutral sphingomyelinase-2
-
DOI 10.1002/hep.21777
-
Rutkute, K., Karakashian, A. A., Giltiay, N. V., Dobierzewska, A., and Nikolova-Karakashian, M. N. (2007) Aging in rat causes hepatic hyperresposiveness to interleukin-1β which is mediated by neutral sphingomyelinase-2. Hepatology 46, 1166-1176 (Pubitemid 350144781)
-
(2007)
Hepatology
, vol.46
, Issue.4
, pp. 1166-1176
-
-
Rutkute, K.1
Karakashian, A.A.2
Giltiay, N.V.3
Dobierzewska, A.4
Nikolova-Karakashian, M.N.5
-
21
-
-
35848937327
-
Regulation of neutral sphingomyelinase-2 by GSH: A new insight to the role of oxidative stress in aging-associated inflammation
-
DOI 10.1194/jlr.M700227-JLR200
-
Rutkute, K., Asmis, R. H., and Nikolova-Karakashian, M. N. (2007) Regulation of neutral sphingomyelinase-2 by GSH. A new insight to the role of oxidative stress in aging-associated inflammation. J. Lipid Res. 48, 2443-2452 (Pubitemid 350058755)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.11
, pp. 2443-2452
-
-
Rutkute, K.1
Asmis, R.H.2
Nikolova-Karakashian, M.N.3
-
22
-
-
0037135626
-
The ceramide-centric universe of lipid-mediated cell regulation: Stress encounters of the lipid kind
-
DOI 10.1074/jbc.R200008200
-
Hannun, Y. A., and Obeid, L. M. (2002) The ceramide-centric universe of lipid-mediated cell regulation. Stress encounters of the lipid kind. J. Biol. Chem. 277, 25847-25850 (Pubitemid 34967060)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.29
, pp. 25847-25850
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
23
-
-
34547513908
-
Regulation of insulin-like growth factor binding protein-1 expression during aging
-
DOI 10.1016/j.bbrc.2007.06.079, PII S0006291X07013095
-
Rutkute, K., and Nikolova-Karakashian, M. N. (2007) Regulation of insulin-like growth factor binding protein-1 expression during aging. Biochem. Biophys. Res. Commun. 361, 263-269 (Pubitemid 47187253)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.361
, Issue.2
, pp. 263-269
-
-
Rutkute, K.1
Nikolova-Karakashian, M.N.2
-
24
-
-
0027989676
-
Interleukin-1 receptor antagonist prevents low dose streptozotocin induced diabetes in mice
-
Sandberg, J. O., Andersson, A., Eizirik, D. L., and Sandler, S. (1994) Interleukin-1 receptor antagonist prevents low dose streptozotocin induced diabetes in mice. Biochem. Biophys. Res. Commun. 202, 543-548
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.202
, pp. 543-548
-
-
Sandberg, J.O.1
Andersson, A.2
Eizirik, D.L.3
Sandler, S.4
-
25
-
-
0035979775
-
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkβ
-
DOI 10.1126/science.1061620
-
Yuan, M., Konstantopoulos, N., Lee, J., Hansen, L., Li, Z.-W., Karin, M., and Shoelson, S. E. (2001) Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IKKβ. Science 293, 1673-1677 (Pubitemid 32807849)
-
(2001)
Science
, vol.293
, Issue.5535
, pp. 1673-1677
-
-
Yuan, M.1
Konstantopoulos, N.2
Lee, J.3
Hansen, L.4
Li, Z.-W.5
Karin, M.6
Shoelson, S.E.7
-
26
-
-
0028825748
-
Tumor necrosis factor α-induced phosphorylation of insulin receptor substrate-1 (IRS-1)
-
Kanety, H., Feinstein, R., Papa, M. Z., Hemi, R., and Karasik, A. (1995) Tumor necrosis factor α-induced phosphorylation of insulin receptor substrate-1 (IRS-1). J. Biol. Chem. 270, 23780-23784
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23780-23784
-
-
Kanety, H.1
Feinstein, R.2
Papa, M.Z.3
Hemi, R.4
Karasik, A.5
-
27
-
-
0037153158
-
A central, role for JNK in obesity and insulin resistance
-
DOI 10.1038/nature01137
-
Hirosumi, J., Tuncman, G., Chang, L., Görgün, C. Z., Uysal, K. T., Maeda, K., Karin, M., and Hotamisligil, G. S. (2002) A central role for JNK in obesity and insulin resistance. Nature 420, 333-336 (Pubitemid 35398190)
-
(2002)
Nature
, vol.420
, Issue.6913
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Gorgun, C.Z.4
Uysal, K.T.5
Maeda, K.6
Karin, M.7
Hotamisligil, G.S.8
-
28
-
-
33845873659
-
Interleukin-1β-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression
-
DOI 10.1210/en.2006-0692
-
Jager, J., Grémeaux, T., Cormont, M., Le Marchand-Brustel, Y., and Tanti, J. F. (2007) Interleukin-1β-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression. Endocrinology 148, 241-251 (Pubitemid 46021456)
-
(2007)
Endocrinology
, vol.148
, Issue.1
, pp. 241-251
-
-
Jager, J.1
Gremeaux, T.2
Cormont, M.3
Le M.-Brustel, Y.4
Tanti, J.-F.5
-
29
-
-
34250004321
-
2-ceramide in CAD cells
-
DOI 10.1111/j.1460-9568.2007.05557.x
-
Arboleda, G., Huang, T. J., Waters, C., Verkhratsky, A., Fernyhough, P., and Gibson, R. M. (2007) Insulin-like growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase-Akt pathway is inhibited by C2-ceramide in CAD cells. Eur. J. Neurosci. 25, 3030-3038 (Pubitemid 46888810)
-
(2007)
European Journal of Neuroscience
, vol.25
, Issue.10
, pp. 3030-3038
-
-
Arboleda, G.1
Huang, T.-J.2
Waters, C.3
Verkhratsky, A.4
Fernyhough, P.5
Gibson, R.M.6
-
30
-
-
40449097575
-
Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide
-
DOI 10.1042/BJ20070936
-
Hajduch, E., Turban, S., Le Liepvre, X., Le Lay, S., Lipina, C., Dimopoulos, N., Dugail, I., and Hundal, H. S. (2008) Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide. Biochem. J. 410, 369-379 (Pubitemid 351346195)
-
(2008)
Biochemical Journal
, vol.410
, Issue.2
, pp. 369-379
-
-
Hajduch, E.1
Turban, S.2
Le, L.X.3
Le, L.S.4
Lipina, C.5
Dimopoulos, N.6
Dugail, I.7
Hundal, H.S.8
-
31
-
-
34250344614
-
Ceramide recruits and activates protein kinase C ζ (PKCζ) within structured membrane microdomains
-
DOI 10.1074/jbc.M700082200
-
Fox, T. E., Houck, K. L., O'Neill, S. M., Nagarajan, M., Stover, T. C., Pomianowski, P. T., Unal, O., Yun, J. K., Naides, S. J., and Kester, M. (2007) Ceramide recruits and activates protein kinase Cζ (PKCζ) within structured membrane microdomains. J. Biol. Chem. 282, 12450-12457 (Pubitemid 47100622)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.17
, pp. 12450-12457
-
-
Fox, T.E.1
Houck, K.L.2
O'Neill, S.M.3
Nagarajan, M.4
Stover, T.C.5
Pomianowski, P.T.6
Unal, O.7
Yun, J.K.8
Naides, S.J.9
Kester, M.10
-
32
-
-
4344614649
-
Regulation of insulin action by ceramide: Dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B
-
DOI 10.1074/jbc.M406499200
-
Stratford, S., Hoehn, K. L., Liu, F., and Summers, S. A. (2004) Regulation of insulin action by ceramide. Dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B. J. Biol. Chem. 279, 36608-36615 (Pubitemid 39129005)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.35
, pp. 36608-36615
-
-
Stratford, S.1
Hoehn, K.L.2
Liu, F.3
Summers, S.A.4
-
33
-
-
0034607914
-
Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473
-
DOI 10.1074/jbc.275.18.13330
-
Schubert, K. M., Scheid, M. P., and Duronio, V. (2000) Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473. J. Biol. Chem. 275, 13330-13335 (Pubitemid 30257390)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.18
, pp. 13330-13335
-
-
Schubert, K.M.1
Scheid, M.P.2
Duronio, V.3
-
34
-
-
0035281991
-
Ceramide dissociates 3′-phosphoinositide production from pleckstrin homology domain translocation
-
DOI 10.1042/0264-6021:3540359
-
Stratford, S., DeWald, D. B., and Summers, S. A. (2001) Ceramide dissociates 3′-phosphoinositide production from pleckstrin homology domain translocation. Biochem. J. 354, 359-368 (Pubitemid 32209874)
-
(2001)
Biochemical Journal
, vol.354
, Issue.2
, pp. 359-368
-
-
Stratford, S.1
DeWald, D.B.2
Summers, S.A.3
-
35
-
-
20744448048
-
Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by mouse Pelle-like kinase/interleukin-1 receptor-associated kinase
-
Kim, J.-A., Yeh, D. C., Ver, M., Li, Y., Carranza, A., Conrads, T. P., Veenstra, T. D., Harrington, M. A., and Quon, M. J. (2005) Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by mouse Pelle-like kinase/interleukin-1 receptor-associated kinase. J. Biol. Chem. 280, 23173-23183
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 23173-23183
-
-
Kim, J.-A.1
Yeh, D.C.2
Ver, M.3
Li, Y.4
Carranza, A.5
Conrads, T.P.6
Veenstra, T.D.7
Harrington, M.A.8
Quon, M.J.9
-
36
-
-
84866122780
-
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
-
Copps, K. D., and White, M. F. (2012) Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2. Diabetologia 55, 2565-2582
-
(2012)
Diabetologia
, vol.55
, pp. 2565-2582
-
-
Copps, K.D.1
White, M.F.2
-
37
-
-
4143050204
-
Insulin resistance due to phosphorylation of insulin receptor substrate-1 at serine 302
-
DOI 10.1074/jbc.M405203200
-
Werner, E. D., Lee, J., Hansen, L., Yuan, M., and Shoelson, S. E. (2004) Insulin resistance Due to phosphorylation of insulin receptor substrate-1 at serine 302. J. Biol. Chem. 279, 35298-35305 (Pubitemid 39100527)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.34
, pp. 35298-35305
-
-
Werner, E.D.1
Lee, J.2
Hansen, L.3
Yuan, M.4
Shoelson, S.E.5
-
38
-
-
78649783839
-
Tumor necrosis factor-α regulates p27 kip expression and apoptosis in smooth muscle cells of human carotid plaques via forkhead transcription factor O1
-
Jia, G., Aggarwal, A., Tyndall, S. H., and Agrawal, D. K. (2011) Tumor necrosis factor-α regulates p27 kip expression and apoptosis in smooth muscle cells of human carotid plaques via forkhead transcription factor O1. Exp. Mol. Pathol. 90, 1-8
-
(2011)
Exp. Mol. Pathol.
, vol.90
, pp. 1-8
-
-
Jia, G.1
Aggarwal, A.2
Tyndall, S.H.3
Agrawal, D.K.4
-
39
-
-
43149103684
-
PP2A regulates the pro-apoptotic activity of FOXO1
-
Yan, L., Lavin, V. A., Moser, L. R., Cui, Q., Kanies, C., and Yang, E. (2008) PP2A regulates the pro-apoptotic activity of FOXO1. J. Biol. Chem. 283, 7411-7420
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 7411-7420
-
-
Yan, L.1
Lavin, V.A.2
Moser, L.R.3
Cui, Q.4
Kanies, C.5
Yang, E.6
-
40
-
-
15444371989
-
JNK regulates lifespan in Caenorhabiditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
-
DOI 10.1073/pnas.0500749102
-
Oh, S. W., Mukhopadhyay, A., Svrzikapa, N., Jiang, F., Davis, R. J., and Tissenbaum, H. A. (2005) JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. Proc. Natl. Acad. Sci. U.S.A. 102, 4494-4499 (Pubitemid 40397140)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.12
, pp. 4494-4499
-
-
Oh, S.W.1
Mukhopadhyay, A.2
Svrzikapa, N.3
Jiang, F.4
Davis, R.J.5
Tissenbaum, H.A.6
-
41
-
-
17044408768
-
JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling
-
Wang, M. C., Bohmann, D., and Jasper, H. (2005) JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Cell 121, 115-125
-
(2005)
Cell
, vol.121
, pp. 115-125
-
-
Wang, M.C.1
Bohmann, D.2
Jasper, H.3
-
42
-
-
11244320393
-
FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK
-
DOI 10.1038/sj.emboj.7600476
-
Essers, M. A., Weijzen, S., de Vries-Smits, A. M., Saarloos, I., de Ruiter, N. D., Bos, J. L., and Burgering, B. M. (2004) FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. EMBO J. 23, 4802-4812 (Pubitemid 40069710)
-
(2004)
EMBO Journal
, vol.23
, Issue.24
, pp. 4802-4812
-
-
Essers, M.A.G.1
Weijzen, S.2
De Vries-Smits, A.M.M.3
Saarloos, I.4
De Ruiter, N.D.5
Bos, J.L.6
Burgering, B.M.T.7
-
43
-
-
22944479314
-
JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3
-
DOI 10.1083/jcb.200409117
-
Sunayama, J., Tsuruta, F., Masuyama, N., and Gotoh, Y. (2005) JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3. J. Cell Biol. 170, 295-304 (Pubitemid 41043811)
-
(2005)
Journal of Cell Biology
, vol.170
, Issue.2
, pp. 295-304
-
-
Sunayama, J.1
Tsuruta, F.2
Masuyama, N.3
Gotoh, Y.4
-
44
-
-
2442429306
-
JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins
-
DOI 10.1038/sj.emboj.7600194
-
Tsuruta, F., Sunayama, J., Mori, Y., Hattori, S., Shimizu, S., Tsujimoto, Y., Yoshioka, K., Masuyama, N., and Gotoh, Y. (2004) JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins. EMBO J. 23, 1889-1899 (Pubitemid 38649651)
-
(2004)
EMBO Journal
, vol.23
, Issue.8
, pp. 1889-1899
-
-
Tsuruta, F.1
Sunayama, J.2
Mori, Y.3
Hattori, S.4
Shimizu, S.5
Tsujimoto, Y.6
Yoshioka, K.7
Masuyama, N.8
Gotoh, Y.9
-
45
-
-
14744301343
-
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage
-
DOI 10.1038/ncb1228
-
Yoshida, K., Yamaguchi, T., Natsume, T., Kufe, D., and Miki, Y. (2005) JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage. Nat. Cell Biol. 7, 278-285 (Pubitemid 40331129)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.3
, pp. 278-285
-
-
Yoshida, K.1
Yamaguchi, T.2
Natsume, T.3
Kufe, D.4
Miki, Y.5
|