Alkaline phosphatase as a treatment of sepsis-associated acute kidney injury

Journal of Pharmacology and Experimental Therapeutics

Volumn 344, Issue 1, 2013, Pages 2-7

  Peters, Esther ^a,b   Van Elsas, Andrea ^c   Heemskerk, Suzanne ^a,b   Jonk, Luigi ^c   Van Der Hoeven, Johannes ^a   Arend, Jacques ^c   Masereeuw, Rosalinde ^b   Pickkers, Peter ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c AM Pharma   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; ALKALINE PHOSPHATASE; ALPHA TOCOPHEROL; BACTERIUM LIPOPOLYSACCHARIDE; BOVINE INTESTINAL ALKALINE PHOSPHATASE; C REACTIVE PROTEIN; CREATININE; ENDOTOXIN; FUROSEMIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 18; INTERLEUKIN 6; KIDNEY INJURY MOLECULE 1; LIPOPOLYSACCHARIDE BINDING PROTEIN; NITRIC OXIDE; NUCLEOTIDASE; PLACEBO; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ABDOMINAL PRESSURE; ACUTE KIDNEY FAILURE; CONTINUOUS INFUSION; CONTRAST INDUCED NEPHROPATHY; CREATININE BLOOD LEVEL; CRITICALLY ILL PATIENT; DEPHOSPHORYLATION; DETOXIFICATION; DISEASE ASSOCIATION; DRUG CLEARANCE; DRUG MECHANISM; DRUG RESEARCH; DRUG SAFETY; DRUG TARGETING; ENDOTOXEMIA; ENZYME BLOOD LEVEL; ENZYMURIA; HEMOFILTRATION; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; INFLAMMATION; INTENSIVE CARE UNIT; KIDNEY FUNCTION; KIDNEY VASCULAR RESISTANCE; LIVER CLEARANCE; LOADING DRUG DOSE; NEPHROTOXICITY; PATHOGENESIS; PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; REVIEW; SEPSIS; SODIUM RETENTION; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT; VASOCONSTRICTION; VASODILATATION; WATER RETENTION;

ACUTE KIDNEY INJURY; ADENOSINE TRIPHOSPHATE; ALKALINE PHOSPHATASE; ANIMALS; CLINICAL TRIALS AS TOPIC; CLINICAL TRIALS, PHASE II AS TOPIC; HUMANS; LIPOPOLYSACCHARIDES; SEPSIS;

EID: 84871672707     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.198226     Document Type: Review

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