Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: A prospective randomized double-blind placebo-controlled trial

Critical Care

Volumn 16, Issue 1, 2012, Pages

  Pickkers, Peter ^a   Heemskerk, Suzanne ^a   Schouten, Jeroen ^b   Laterre, Pierre François ^c   Vincent, Jean Louis ^d   Beishuizen, Albertus ^e   Jorens, Philippe G ^f   Spapen, Herbert ^g   Bulitta, Michael ^h   Peters, Wilbert H M ^a   van der Hoeven, Johannes G ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CANISIUS WILHELMINA HOSPITAL   (Netherlands)

^c CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^d ERASME HOSPITAL   (Belgium)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^f Department of Intensive Care Medicine   (Belgium)

^g UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^h CRM Biometrics GmbH   (Germany)

Author keywords

Acute renal failure; Sepsis; Septic shock; Systemic inflammatory response syndrome; Therapy

Indexed keywords

ALKALINE PHOSPHATASE; C REACTIVE PROTEIN; CREATININE; INTERLEUKIN 18; INTERLEUKIN 6; KIDNEY INJURY MOLECULE 1; LIPOPOLYSACCHARIDE BINDING PROTEIN; PLACEBO;

ABDOMINAL PAIN; ACUTE KIDNEY FAILURE; AGED; ARTICLE; BRADYCARDIA; BRAIN TUMOR; CALCIUM BLOOD LEVEL; CLINICAL ARTICLE; COMA; CONSCIOUSNESS DISORDER; CONSTIPATION; CONTINUOUS INFUSION; CONTROLLED STUDY; CREATININE CLEARANCE; CRITICALLY ILL PATIENT; DECUBITUS; DELIRIUM; DIALYSIS; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG FEVER; DRUG SAFETY; ECG ABNORMALITY; ELECTROLYTE DISTURBANCE; FEMALE; GALLBLADDER NECROSIS; HEART ARREST; HEART ATRIUM FIBRILLATION; HEART ATRIUM FLUTTER; HUMAN; HYPERLACTATEMIA; HYPOTENSION; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY TUBULE DAMAGE; LIVER NECROSIS; MALE; OSTEOMYELITIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; QT PROLONGATION; RANDOMIZED CONTROLLED TRIAL; RENAL REPLACEMENT THERAPY; RESPIRATORY FAILURE; RESTLESSNESS; SEPTIC SHOCK; SIDE EFFECT; STOMACH EMPTYING; TREATMENT DURATION; TREATMENT OUTCOME; UREMIA; URINARY EXCRETION; CONTROLLED CLINICAL TRIAL; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHASE 2 CLINICAL TRIAL; SEPSIS; VERY ELDERLY;

ACUTE KIDNEY INJURY; AGED; AGED, 80 AND OVER; ALKALINE PHOSPHATASE; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SEPSIS; TREATMENT OUTCOME;

EID: 84856047126     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc11159     Document Type: Article

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