Alkaline phosphatases reduce toxicity of lipopolysaccharides in vivo and in vitro through dephosphorylation

Clinical Biochemistry

Volumn 35, Issue 6, 2002, Pages 455-461

  Koyama, Iwao ^a   Matsunaga, Toshiyuki ^a   Harada, Tsuyoshi ^a   Hokari, Shigeru ^a   Komoda, Tsugikazu ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Alkaline phosphatase; Cell culture; Inducible nitric oxide synthase; Interleukin 6; Lipopolysaccharide; Surfactant like particle

Indexed keywords

ALKALINE PHOSPHATASE; BACTERIUM LIPOPOLYSACCHARIDE; ISOENZYME; PHENYLALANINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD LEVEL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DEPHOSPHORYLATION; ENDOTHELIUM CELL; ESCHERICHIA COLI; GASTROINTESTINAL TRACT; HOST RESISTANCE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; TOXICITY;

ADMINISTRATION, ORAL; ALKALINE PHOSPHATASE; ANIMALS; ANTIGENS, NEOPLASM; BLOTTING, WESTERN; DUODENUM; LIPOPOLYSACCHARIDES; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; RATS; RATS, WISTAR;

EID: 0036754165     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(02)00330-2     Document Type: Article

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