Beneficial effects of alkaline phosphatase in septic shock

Critical Care Medicine

Volumn 34, Issue 8, 2006, Pages 2182-2187

  Su, Fuhong ^a   Brands, Ruud ^c   Wang, Zhen ^a   Verdant, Colin ^a   Bruhn, Alejandro ^a   Cai, Ying ^b   Raaben, Willem ^c   Wulferink, Marty ^c   Vincent, Jean Louis ^a  

^a ERASME HOSPITAL   (Belgium)

^b FREE UNIVERSITY OF BRUSSELS   (Belgium)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Gas exchange; Lipopolysaccharide; Peritonitis; Sheep

Indexed keywords

ALKALINE PHOSPHATASE; HETASTARCH; INTERLEUKIN 6; RINGER LACTATE SOLUTION; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEATH; DIURESIS; DRUG EFFECT; DRUG EFFICACY; FEMALE; GAS EXCHANGE; HEMODYNAMICS; HYPOVOLEMIA; MORTALITY; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SEPTIC SHOCK; SHEEP; STATISTICAL SIGNIFICANCE; SURVIVAL TIME; ANIMAL; BLOOD; DISEASE MODEL; INTRAVENOUS DRUG ADMINISTRATION; LUNG GAS EXCHANGE; RANDOMIZATION; SURVIVAL;

ALKALINE PHOSPHATASE; ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; INFUSIONS, INTRAVENOUS; INTERLEUKIN-6; OXYGEN; PULMONARY GAS EXCHANGE; RANDOM ALLOCATION; SHEEP; SHOCK, SEPTIC; SURVIVAL ANALYSIS;

EID: 33748108004     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000229887.70579.29     Document Type: Article

References (35)

1. Opal SM, Scannon PJ, Vincent JL, et al: Relationship between plasma levels of lipopolysaccharide (LPS) and LPS-binding protein in patients with severe sepsis and septic shock. J Infect Dis 1999; 180:1584-1589
2. Corriveau CC, Danner RL: Endotoxin as a therapeutic target in septic shock. Infect Agents Dis 1993; 2:35-43
3. McComb RB, Bowers GN, Posen S. Distribution in nature. In: Alkaline Phosphatase. McComb RB, Bowers GN, Posen S (Eds). New York, Plenum Press, 1979, pp 127-152
4. Fedde KN, Blair L, Silverstein J, et al: Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia. J Bone Miner Res 1999; 14:2015-2026
5. Koyama I, Matsunaga T, Harada T, et al: Alkaline phosphatases reduce toxicity of lipopolysaccharides in vivo and in vitro through dephosphorylation. Clin Biochem 2002; 35:455-461
6. Poelstra K, Bakker WW, Klok PA, et al: Dephosphorylation of endotoxin by alkaline phosphatase in vivo. Am J Pathol 1997; 151:1163-1169
7. Yao Z, Foster PA, Gross GJ: Monophosphoryl lipid A protects against endotoxic shock via inhibiting neutrophil infiltration and preventing disseminated intravascular coagulation. Circ Shock 1994; 43:107-114
8. Poelstra K, Bakker WW, Klok PA, et al: A physiologic function for alkaline phosphatase: Endotoxin detoxification. Lab Invest 1997; 76:319-327
9. Bentala H, Verweij WR, Huizinga-Van der Vlag A, et al: Removal of phosphate from lipid A as a strategy to detoxify lipopolysaccharide. Shock 2002; 18:561-566
10. Verweij WR, Bentala H, Huizinga-Van der Vlag A, et al: Protection against an Escherichia coli-induced sepsis by alkaline phosphatase in mice. Shock 2004; 22:174-179
11. van Veen SQ, van Vliet AK, Wulferink M, et al: Bovine intestinal alkaline phosphatase attenuates the inflammatory response in secondary peritonitis in mice. Infect Immun 2005; 73:4309-4314
12. Sun Q, Dimopoulos G, Nguyen DN, et al: Low-dose vasopressin in the treatment of septic shock in sheep. Am J Respir Crit Care Med 2003; 168:481-486
13. Su F, Nguyen ND, Creteur J, et al: Use of low tidal volume in septic shock may decrease severity of subsequent acute lung injury. Shock 2004; 22:145-150
14. Dubois EF. The estimation of the surface area of the body. In: Basal Metabolism in Health and Disease. Dubois EF (Ed). Philadelphia, Lea & Febiger, 1936, pp 125-144
15. Su F, Nguyen ND, Wang Z, et al: Fever control in septic shock: Beneficial or harmful? Shock 2005; 23:516-520
16. Bergmeyer HU. Methods of Enzymatic Analysis. Third Edition. Weinheim, Vch Pub, 1983
17. Kapojos JJ, Poelstra K, Borghuis T, et al: Induction of glomerular alkaline phosphatase after challenge with lipopolysaccharide. Int J Exp Pathol 2003; 84:135-144
18. Baluna R, Vitetta ES: Vascular leak syndrome: A side effect of immunotherapy. Immunopharmacology 1997; 37:117-132
19. Navaratnam RL, Morris SE, Traber DL, et al: Endotoxin (LPS) increases mesenteric vascular resistance (MVR) and bacterial translocation (BT). J Trauma 1990; 30:1104-1113
20. Deitch EA: The role of intestinal barrier failure and bacterial translocation in the development of systemic infection and multiple organ failure. Arch Surg 1990; 125:403-404
21. Rudbach JA, Myers KR, Rechtman RE: Prophylactic use of monophophyl lipid A in patients at risk for sepsis. In: Bacterial Endotoxins: Basic Science to Anti-Sepsis Strategies. Levin J, van Deventer SJH, Van der Poll T (Eds). New York, Wiley-Liss, 1994, pp 463-467
22. De Becker G, Moulin V, Pajak B, et al: The adjuvant monophosphoryl lipid A increases the function of antigen-presenting cells. Int Immunol 2000; 12:807-815
23. Ismaili J, Rennesson J, Aksoy E, et al: Monophosphoryl lipid A activates both human dendritic cells and T cells. J Immunol 2002; 168:926-932
24. Klaus S, Staubach KH, Heringlake M, et al: Tissue metabolism during endotoxin shock after pretreatment with monophosphoryl lipid A. Cardiovasc Res 2003; 59:105-112
25. Harada T, Koyama I, Shimoi A, et al: Identification of pulmonary surfactant that bears intestinal-type and tissue-nonspecific-type alkaline phosphatase in endotoxin-induced rat bronchoalveolar fluid. Cell Tissue Res 2002; 307:69-77
26. Beumer C, Wulferink M, Raaben W, et al: Calf intestinal alkaline phosphatase, a novel therapeutic drug for lipopolysaccharide (LPS)-mediated diseases, attenuates LPS toxicity in mice and piglets. J Pharmacol Exp Ther 2003; 307:737-744
27. Papanicolaou DA, Wilder RL, Manolagas SC, et al: The pathophysiologic roles of interleukin-6 in human disease. Ann Intern Med 1998; 128:127-137
28. Casey LC, Balk RA, Bone RC: Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann Intern Med 1993; 119:771-778
29. Remick DG, Bolgos GR, Siddiqui J, et al: Six at six: interleukin-6 measured 6 h after the initiation of sepsis predicts mortality over 3 days. Shock 2002; 17:463-467
30. Oda S, Hirasawa H, Shiga H, et al: Sequential measurement of IL-6 blood levels in patients with systemic inflammatory response syndrome (SIRS)/sepsis. Cytokine 2005; 29:169-175
31. Frutos-Vivar F, Nin N, Esteban A: Epidemiology of acute lung injury and acute respiratory distress syndrome. Curr Opin Crit Care 2004; 10:1-6
32. Su X, Song Y, Jiang J, et al: The role of aquaporin-1 (AQP1) expression in a murine model of lipopolysaccharide-induced acute lung injury. Respir Physiol Neurobiol 2004; 142:1-11
33. Jeyaseelan S, Chu HW, Young SK, et al: Transcriptional profiling of lipopolysaccharide-induced acute lung injury. Infect Immun 2004; 72:7247-7256
34. Lopez A, Yong S: Injury versus inflammatory response in the lungs of rats intratracheally inoculated with bacterial lipopolysaccharide. Am J Vet Res 1986; 47:1287-1292
35. Echtenacher B, Freudenberg MA, Jack RS, et al: Differences in innate defense mechanisms in endotoxemia and polymicrobial septic peritonitis. Infect Immun 2001; 69:7271-7276