메뉴 건너뛰기




Volumn 154, Issue 1, 2013, Pages 34-45

Promoter demethylation of cystathionine-β-synthetase gene contributes to inflammatory pain in rats

Author keywords

Cystathionine synthetase; DNA demethylation; Dorsal root ganglia; Epigenetics; Inflammatory pain; Voltage gated sodium channels

Indexed keywords

AMINOOXYACETIC ACID; BISULFITE; CYSTATHIONINE BETA SYNTHASE; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; HYDROGEN SULFIDE; HYDROXYLAMINE; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; TETRODOTOXIN;

EID: 84871634253     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2012.07.031     Document Type: Article
Times cited : (81)

References (68)
  • 1
    • 0029876402 scopus 로고    scopus 로고
    • The possible role of hydrogen sulfide as an endogenous neuromodulator
    • K. Abe, and H. Kimura The possible role of hydrogen sulfide as an endogenous neuromodulator J Neurosci 16 1996 1066 1071 (Pubitemid 26140863)
    • (1996) Journal of Neuroscience , vol.16 , Issue.3 , pp. 1066-1071
    • Abe, K.1    Kimura, H.2
  • 2
    • 77956485440 scopus 로고    scopus 로고
    • Inhibition of class II histone deacetylases in the spinal cord attenuates inflammatory hyperalgesia
    • G. Bai, D. Wei, S. Zou, K. Ren, and R. Dubner Inhibition of class II histone deacetylases in the spinal cord attenuates inflammatory hyperalgesia Mol Pain 6 2010 51
    • (2010) Mol Pain , vol.6 , pp. 51
    • Bai, G.1    Wei, D.2    Zou, S.3    Ren, K.4    Dubner, R.5
  • 5
    • 0042819716 scopus 로고    scopus 로고
    • Selective up-regulation of the growth arrest DNA damage-inducible gene Gadd45 alpha in sensory and motor neurons after peripheral nerve injury
    • DOI 10.1046/j.1460-9568.2003.02827.x
    • K. Befort, L. Karchewski, C. Lanoue, and C.J. Woolf Selective up-regulation of the growth arrest DNA damage-inducible gene Gadd45 alpha in sensory and motor neurons after peripheral nerve injury Eur J Neurosci 18 2003 911 922 (Pubitemid 37059701)
    • (2003) European Journal of Neuroscience , vol.18 , Issue.4 , pp. 911-922
    • Befort, K.1    Karchewski, L.2    Lanoue, C.3    Woolf, C.J.4
  • 6
    • 19944425183 scopus 로고    scopus 로고
    • Hydrogen sulphide is a mediator of carrageenan-induced hindpaw oedema in the rat
    • DOI 10.1038/sj.bjp.0706186
    • M. Bhatia, J. Sidhapuriwala, S.M. Moochhala, and P.K. Moore Hydrogen sulphide is a mediator of carrageenan-induced hindpaw oedema in the rat Br J Pharmacol 145 2005 141 144 (Pubitemid 40756518)
    • (2005) British Journal of Pharmacology , vol.145 , Issue.2 , pp. 141-144
    • Bhatia, M.1    Sidhapuriwala, J.2    Moochhala, S.M.3    Moore, P.K.4
  • 7
    • 0033580326 scopus 로고    scopus 로고
    • A mammalian protein with specific demethylase activity for mCpG DNA
    • S.K. Bhattacharya, S. Ramchandani, N. Cervoni, and M. Szyf A mammalian protein with specific demethylase activity for mCpG DNA Nature 397 1999 579 583
    • (1999) Nature , vol.397 , pp. 579-583
    • Bhattacharya, S.K.1    Ramchandani, S.2    Cervoni, N.3    Szyf, M.4
  • 8
    • 1542498432 scopus 로고    scopus 로고
    • Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain
    • DOI 10.1016/j.pain.2003.12.035, PII S0304395904000028
    • J.A. Black, S. Liu, M. Tanaka, T.R. Cummins, and S.G. Waxman Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain PAIN® 108 2004 237 247 (Pubitemid 38353046)
    • (2004) Pain , vol.108 , Issue.3 , pp. 237-247
    • Black, J.A.1    Liu, S.2    Tanaka, M.3    Cummins, T.R.4    Waxman, S.G.5
  • 9
    • 63849253345 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase in the anterior cingulate cortex contributes to the induction and expression of affective pain
    • H. Cao, Y.J. Gao, W.H. Ren, T.T. Li, K.Z. Duan, Y.H. Cui, X.H. Cao, Z.Q. Zhao, R.R. Ji, and Y.Q. Zhang Activation of extracellular signal-regulated kinase in the anterior cingulate cortex contributes to the induction and expression of affective pain J Neurosci 29 2009 3307 3321
    • (2009) J Neurosci , vol.29 , pp. 3307-3321
    • Cao, H.1    Gao, Y.J.2    Ren, W.H.3    Li, T.T.4    Duan, K.Z.5    Cui, Y.H.6    Cao, X.H.7    Zhao, Z.Q.8    Ji, R.R.9    Zhang, Y.Q.10
  • 11
    • 79956294973 scopus 로고    scopus 로고
    • DNA methylation and demethylation in mammals
    • Z.X. Chen, and A.D. Riggs DNA methylation and demethylation in mammals J Biol Chem 286 2011 18347 18353
    • (2011) J Biol Chem , vol.286 , pp. 18347-18353
    • Chen, Z.X.1    Riggs, A.D.2
  • 14
    • 0032723079 scopus 로고    scopus 로고
    • Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain
    • S.D. Dib-Hajj, J. Fjell, T.R. Cummins, Z. Zheng, K. Fried, R. LaMotte, J.A. Black, and S.G. Waxman Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain PAIN® 83 1999 591 600
    • (1999) PAIN® , vol.83 , pp. 591-600
    • Dib-Hajj, S.D.1    Fjell, J.2    Cummins, T.R.3    Zheng, Z.4    Fried, K.5    Lamotte, R.6    Black, J.A.7    Waxman, S.G.8
  • 18
    • 0033560866 scopus 로고    scopus 로고
    • CAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS
    • DOI 10.1111/j.1469-7793.1999.0433v.x
    • E.M. Fitzgerald, K. Okuse, J.N. Wood, A.C. Dolphin, and S.J. Moss CAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS J Physiol 516 1999 433 446 (Pubitemid 29204448)
    • (1999) Journal of Physiology , vol.516 , Issue.2 , pp. 433-446
    • Fitzgerald, E.M.1    Okuse, K.2    Wood, J.N.3    Dolphin, A.C.4    Moss, S.J.5
  • 19
    • 77957659555 scopus 로고    scopus 로고
    • Cytidine deaminases: AIDing DNA demethylation?
    • E.L. Fritz, and F.N. Papavasiliou Cytidine deaminases: AIDing DNA demethylation? Genes Dev 24 2010 2107 2114
    • (2010) Genes Dev , vol.24 , pp. 2107-2114
    • Fritz, E.L.1    Papavasiliou, F.N.2
  • 21
  • 22
    • 0032535602 scopus 로고    scopus 로고
    • 2- induced sensitization of rat sensory neurons in vitro
    • M.S. Gold, J.D. Levine, and A.M. Correa Modulation of TTX-R INa by PKC and PKA and their role in PGE2-induced sensitization of rat sensory neurons in vitro J Neurosci 18 1998 10345 10355 (Pubitemid 29016554)
    • (1998) Journal of Neuroscience , vol.18 , Issue.24 , pp. 10345-10355
    • Gold, M.S.1    Levine, J.D.2    Correa, A.M.3
  • 25
    • 58149145316 scopus 로고    scopus 로고
    • Gadd45 modulation of intrinsic and extrinsic stress responses in myeloid cells
    • B. Hoffman, and D.A. Liebermann Gadd45 modulation of intrinsic and extrinsic stress responses in myeloid cells J Cell Physiol 218 2009 26 31
    • (2009) J Cell Physiol , vol.218 , pp. 26-31
    • Hoffman, B.1    Liebermann, D.A.2
  • 29
    • 33745811234 scopus 로고    scopus 로고
    • The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells
    • DOI 10.1074/jbc.M513249200
    • H. Li, T. Rauch, Z.X. Chen, P.E. Szabo, A.D. Riggs, and G.P. Pfeifer The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells J Biol Chem 281 2006 19489 19500 (Pubitemid 44035453)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.28 , pp. 19489-19500
    • Li, H.1    Rauch, T.2    Chen, Z.-X.3    Szabo, P.E.4    Riggs, A.D.5    Pfeifer, G.P.6
  • 31
    • 0346496028 scopus 로고    scopus 로고
    • Gadd45β is important for perpetuating cognate and inflammatory signals in T cells
    • DOI 10.1038/ni1020
    • B. Lu, A.F. Ferrandino, and R.A. Flavell Gadd45beta is important for perpetuating cognate and inflammatory signals in T cells Nat Immunol 5 2004 38 44 (Pubitemid 38081467)
    • (2004) Nature Immunology , vol.5 , Issue.1 , pp. 38-44
    • Lu, B.1    Fernandino, A.F.2    Flavell, R.A.3
  • 33
    • 66849119061 scopus 로고    scopus 로고
    • DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation
    • D.K. Ma, J.U. Guo, G.L. Ming, and H. Song DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation Cell Cycle 8 2009 1526 1531
    • (2009) Cell Cycle , vol.8 , pp. 1526-1531
    • Ma, D.K.1    Guo, J.U.2    Ming, G.L.3    Song, H.4
  • 35
    • 60049083958 scopus 로고    scopus 로고
    • Hyperalgesia induced by spinal and peripheral hydrogen sulfide: Evidence for involvement of Cav3.2 T-type calcium channels
    • Y. Maeda, Y. Aoki, F. Sekiguchi, M. Matsunami, T. Takahashi, H. Nishikawa, and A. Kawabata Hyperalgesia induced by spinal and peripheral hydrogen sulfide: evidence for involvement of Cav3.2 T-type calcium channels PAIN® 142 2009 127 132
    • (2009) PAIN® , vol.142 , pp. 127-132
    • Maeda, Y.1    Aoki, Y.2    Sekiguchi, F.3    Matsunami, M.4    Takahashi, T.5    Nishikawa, H.6    Kawabata, A.7
  • 36
    • 33846863372 scopus 로고    scopus 로고
    • Effect of 8-bromo-cAMP on the tetrodotoxin-resistant sodium (Nav 1.8) current in small-diameter nodose ganglion neurons
    • DOI 10.1016/j.neuropharm.2006.10.008, PII S0028390806003625
    • S. Matsumoto, S. Yoshida, M. Ikeda, T. Tanimoto, C. Saiki, M. Takeda, Y. Shima, and H. Ohta Effect of 8-bromo-cAMP on the tetrodotoxin-resistant sodium (Nav 1.8) current in small-diameter nodose ganglion neurons Neuropharmacology 52 2007 904 924 (Pubitemid 46227480)
    • (2007) Neuropharmacology , vol.52 , Issue.3 , pp. 904-924
    • Matsumoto, S.1    Yoshida, S.2    Ikeda, M.3    Tanimoto, T.4    Saiki, C.5    Takeda, M.6    Shima, Y.7    Ohta, H.8
  • 38
    • 56749104311 scopus 로고    scopus 로고
    • H2S-donating sildenafil (ACS6) inhibits superoxide formation and gp91phox expression in arterial endothelial cells: Role of protein kinases A and G
    • S. Muzaffar, J.Y. Jeremy, A. Sparatore, P. Del Soldato, G.D. Angelini, and N. Shukla H2S-donating sildenafil (ACS6) inhibits superoxide formation and gp91phox expression in arterial endothelial cells: role of protein kinases A and G Br J Pharmacol 155 2008 984 994
    • (2008) Br J Pharmacol , vol.155 , pp. 984-994
    • Muzaffar, S.1    Jeremy, J.Y.2    Sparatore, A.3    Del Soldato, P.4    Angelini, G.D.5    Shukla, N.6
  • 39
    • 79953713233 scopus 로고    scopus 로고
    • Aberrant DNA hypermethylation patterns lead to transcriptional silencing of tumor suppressor genes in UVB-exposed skin and UVB-induced skin tumors of mice
    • V. Nandakumar, M. Vaid, T.O. Tollefsbol, and S.K. Katiyar Aberrant DNA hypermethylation patterns lead to transcriptional silencing of tumor suppressor genes in UVB-exposed skin and UVB-induced skin tumors of mice Carcinogenesis 32 2011 597 604
    • (2011) Carcinogenesis , vol.32 , pp. 597-604
    • Nandakumar, V.1    Vaid, M.2    Tollefsbol, T.O.3    Katiyar, S.K.4
  • 40
    • 25444486938 scopus 로고    scopus 로고
    • 2+ channel-dependent sensitization of a novel subpopulation of rat peripheral nociceptors
    • DOI 10.1523/JNEUROSCI.2527-05.2005
    • 2+ channel-dependent sensitization of a novel subpopulation of rat peripheral nociceptors J Neurosci 25 2005 8766 8775 (Pubitemid 41362055)
    • (2005) Journal of Neuroscience , vol.25 , Issue.38 , pp. 8766-8775
    • Nelson, M.T.1    Joksovic, P.M.2    Perez-Reyes, E.3    Todorovic, S.M.4
  • 42
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • DOI 10.1016/S0092-8674(00)81656-6
    • M. Okano, D.W. Bell, D.A. Haber, and E. Li DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development Cell 99 1999 247 257 (Pubitemid 29519904)
    • (1999) Cell , vol.99 , Issue.3 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 45
    • 2542614470 scopus 로고    scopus 로고
    • 2S) stimulates capsaicin-sensitive primary afferent neurons in the rat urinary bladder
    • DOI 10.1038/sj.bjp.0705764
    • R. Patacchini, P. Santicioli, S. Giuliani, and C.A. Maggi Hydrogen sulfide (H2S) stimulates capsaicin-sensitive primary afferent neurons in the rat urinary bladder Br J Pharmacol 142 2004 31 34 (Pubitemid 38698190)
    • (2004) British Journal of Pharmacology , vol.142 , Issue.1 , pp. 31-34
    • Patacchini, R.1    Santicioli, P.2    Giuliani, S.3    Maggi, C.A.4
  • 46
    • 57649196594 scopus 로고    scopus 로고
    • DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
    • K. Rai, I.J. Huggins, S.R. James, A.R. Karpf, D.A. Jones, and B.R. Cairns DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45 Cell 135 2008 1201 1212
    • (2008) Cell , vol.135 , pp. 1201-1212
    • Rai, K.1    Huggins, I.J.2    James, S.R.3    Karpf, A.R.4    Jones, D.A.5    Cairns, B.R.6
  • 47
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • DOI 10.1038/nature05918, PII NATURE05918
    • W. Reik Stability and flexibility of epigenetic gene regulation in mammalian development Nature 447 2007 425 432 (Pubitemid 46816749)
    • (2007) Nature , vol.447 , Issue.7143 , pp. 425-432
    • Reik, W.1
  • 49
    • 66649125759 scopus 로고    scopus 로고
    • Role of hydrogen sulfide in visceral nociception
    • M. Schemann, and D. Grundy Role of hydrogen sulfide in visceral nociception Gut 58 2009 744 747
    • (2009) Gut , vol.58 , pp. 744-747
    • Schemann, M.1    Grundy, D.2
  • 50
    • 59849090498 scopus 로고    scopus 로고
    • TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation
    • K.M. Schmitz, N. Schmitt, U. Hoffmann-Rohrer, A. Schafer, I. Grummt, and C. Mayer TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation Mol Cell 33 2009 344 353
    • (2009) Mol Cell , vol.33 , pp. 344-353
    • Schmitz, K.M.1    Schmitt, N.2    Hoffmann-Rohrer, U.3    Schafer, A.4    Grummt, I.5    Mayer, C.6
  • 51
    • 79955662370 scopus 로고    scopus 로고
    • H2S protects hippocampal neurons from anoxia-reoxygenation through cAMP-mediated PI3K/Akt/p70S6K cell-survival signaling pathways
    • J.L. Shao, X.H. Wan, Y. Chen, C. Bi, H.M. Chen, Y. Zhong, X.H. Heng, and J.Q. Qian H2S protects hippocampal neurons from anoxia-reoxygenation through cAMP-mediated PI3K/Akt/p70S6K cell-survival signaling pathways J Mol Neurosci 43 2011 453 460
    • (2011) J Mol Neurosci , vol.43 , pp. 453-460
    • Shao, J.L.1    Wan, X.H.2    Chen, Y.3    Bi, C.4    Chen, H.M.5    Zhong, Y.6    Heng, X.H.7    Qian, J.Q.8
  • 52
    • 70449646830 scopus 로고    scopus 로고
    • Hydrogen sulfide's involvement in modulating nociception
    • H.S. Smith Hydrogen sulfide's involvement in modulating nociception Pain Physician 12 2009 901 910
    • (2009) Pain Physician , vol.12 , pp. 901-910
    • Smith, H.S.1
  • 53
    • 77953023713 scopus 로고    scopus 로고
    • Upregulation of Ca(v)3.2 T-type calcium channels targeted by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain
    • T. Takahashi, Y. Aoki, K. Okubo, Y. Maeda, F. Sekiguchi, K. Mitani, H. Nishikawa, and A. Kawabata Upregulation of Ca(v)3.2 T-type calcium channels targeted by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain PAIN® 150 2010 183 191
    • (2010) PAIN® , vol.150 , pp. 183-191
    • Takahashi, T.1    Aoki, Y.2    Okubo, K.3    Maeda, Y.4    Sekiguchi, F.5    Mitani, K.6    Nishikawa, H.7    Kawabata, A.8
  • 55
    • 27844442224 scopus 로고    scopus 로고
    • ATP channels by exogenous and endogenous hydrogen sulfide in vascular smooth muscle cells
    • DOI 10.1124/mol.105.017467
    • G. Tang, L. Wu, W. Liang, and R. Wang Direct stimulation of K(ATP) channels by exogenous and endogenous hydrogen sulfide in vascular smooth muscle cells Mol Pharmacol 68 2005 1757 1764 (Pubitemid 41654358)
    • (2005) Molecular Pharmacology , vol.68 , Issue.6 , pp. 1757-1764
    • Tang, G.1    Wu, L.2    Liang, W.3    Wang, R.4
  • 56
    • 77953850310 scopus 로고    scopus 로고
    • Interaction of hydrogen sulfide with ion channels
    • G. Tang, L. Wu, and R. Wang Interaction of hydrogen sulfide with ion channels Clin Exp Pharmacol Physiol 37 2010 753 763
    • (2010) Clin Exp Pharmacol Physiol , vol.37 , pp. 753-763
    • Tang, G.1    Wu, L.2    Wang, R.3
  • 58
    • 59749090393 scopus 로고    scopus 로고
    • The peripheral pro-nociceptive state induced by repetitive inflammatory stimuli involves continuous activation of protein kinase A and protein kinase C epsilon and its Na(V)1.8 sodium channel functional regulation in the primary sensory neuron
    • C.F. Villarreal, D. Sachs, M.I. Funez, C.A. Parada, F. de Queiroz Cunha, and S.H. Ferreira The peripheral pro-nociceptive state induced by repetitive inflammatory stimuli involves continuous activation of protein kinase A and protein kinase C epsilon and its Na(V)1.8 sodium channel functional regulation in the primary sensory neuron Biochem Pharmacol 77 2009 867 877
    • (2009) Biochem Pharmacol , vol.77 , pp. 867-877
    • Villarreal, C.F.1    Sachs, D.2    Funez, M.I.3    Parada, C.A.4    De Queiroz Cunha, F.5    Ferreira, S.H.6
  • 59
    • 0036845556 scopus 로고    scopus 로고
    • 2S be the third endogenous gaseous transmitter?
    • DOI 10.1096/fj.02-0211hyp
    • R. Wang Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter? FASEB J 16 2002 1792 1798 (Pubitemid 35340360)
    • (2002) FASEB Journal , vol.16 , Issue.13 , pp. 1792-1798
    • Wang, R.1
  • 61
    • 0030572637 scopus 로고    scopus 로고
    • DNA demethylation in vitro: Involvement of RNA
    • DOI 10.1016/S0092-8674(00)80146-4
    • A. Weiss, I. Keshet, A. Razin, and H. Cedar DNA demethylation in vitro: involvement of RNA Cell 86 1996 709 718 (Pubitemid 26303440)
    • (1996) Cell , vol.86 , Issue.5 , pp. 709-718
    • Weiss, A.1    Keshet, I.2    Razin, A.3    Cedar, H.4
  • 62
    • 0036139259 scopus 로고    scopus 로고
    • Peripheral inflammation sensitizes P2X receptor-mediated responses in rat dorsal root ganglion neurons
    • G.Y. Xu, and L.Y. Huang Peripheral inflammation sensitizes P2X receptor-mediated responses in rat dorsal root ganglion neurons J Neurosci 22 2002 93 102
    • (2002) J Neurosci , vol.22 , pp. 93-102
    • Xu, G.Y.1    Huang, L.Y.2
  • 63
    • 4143089311 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II potentiates ATP responses by promoting trafficking of P2X receptors
    • 2+/calmodulin-dependent protein kinase II potentiates ATP responses by promoting trafficking of P2X receptors Proc Natl Acad Sci USA 101 2004 11868 11873
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11868-11873
    • Xu, G.Y.1    Huang, L.Y.2
  • 64
    • 69549118509 scopus 로고    scopus 로고
    • The endogenous hydrogen sulfide producing enzyme cystathionine-beta synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome
    • G.Y. Xu, J.H. Winston, M. Shenoy, S. Zhou, J.D. Chen, and P.J. Pasricha The endogenous hydrogen sulfide producing enzyme cystathionine-beta synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome Mol Pain 5 2009 44
    • (2009) Mol Pain , vol.5 , pp. 44
    • Xu, G.Y.1    Winston, J.H.2    Shenoy, M.3    Zhou, S.4    Chen, J.D.5    Pasricha, P.J.6
  • 65
    • 79955878897 scopus 로고    scopus 로고
    • Antisense-mediated knockdown of Na(V)1.8, but not Na(V)1.9, generates inhibitory effects on complete Freund's adjuvant-induced inflammatory pain in rat
    • Y.Q. Yu, F. Zhao, S.M. Guan, and J. Chen Antisense-mediated knockdown of Na(V)1.8, but not Na(V)1.9, generates inhibitory effects on complete Freund's adjuvant-induced inflammatory pain in rat PLoS One 6 2011 e19865
    • (2011) PLoS One , vol.6 , pp. 19865
    • Yu, Y.Q.1    Zhao, F.2    Guan, S.M.3    Chen, J.4
  • 67
    • 81255185288 scopus 로고    scopus 로고
    • Epigenetic suppression of GAD65 expression mediates persistent pain
    • Z. Zhang, Y.Q. Cai, F. Zou, B. Bie, and Z.Z. Pan Epigenetic suppression of GAD65 expression mediates persistent pain Nat Med 17 2011 1448
    • (2011) Nat Med , vol.17 , pp. 1448
    • Zhang, Z.1    Cai, Y.Q.2    Zou, F.3    Bie, B.4    Pan, Z.Z.5
  • 68
    • 0034326849 scopus 로고    scopus 로고
    • 5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence
    • B. Zhu, Y. Zheng, H. Angliker, S. Schwarz, S. Thiry, M. Siegmann, and J.P. Jost 5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence Nucleic Acids Res 28 2000 4157 4165
    • (2000) Nucleic Acids Res , vol.28 , pp. 4157-4165
    • Zhu, B.1    Zheng, Y.2    Angliker, H.3    Schwarz, S.4    Thiry, S.5    Siegmann, M.6    Jost, J.P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.