메뉴 건너뛰기




Volumn 24, Issue 19, 2010, Pages 2107-2114

Cytidine deaminases: AIDing DNA demethylation?

Author keywords

Active demethylation; AICDA; AID; Cytidine deaminase; Epigenetic reprogramming

Indexed keywords

CYTIDINE DEAMINASE; AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE);

EID: 77957659555     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1963010     Document Type: Review
Times cited : (107)

References (74)
  • 2
    • 77950630042 scopus 로고    scopus 로고
    • Molecular characterization of Pleurodeles waltl activation-induced cytidine deaminase
    • Bascove M, Frippiat JP. 2010. Molecular characterization of Pleurodeles waltl activation-induced cytidine deaminase. Mol Immunol 47: 1640-1649.
    • (2010) Mol Immunol , vol.47 , pp. 1640-1649
    • Bascove, M.1    Frippiat, J.P.2
  • 3
    • 0033580326 scopus 로고    scopus 로고
    • A mammalian protein with specific demethylase activity for mCpG DNA
    • Bhattacharya SK, Ramchandani S, Cervoni N, Szyf M. 1999. A mammalian protein with specific demethylase activity for mCpG DNA. Nature 397: 579-583.
    • (1999) Nature , vol.397 , pp. 579-583
    • Bhattacharya, S.K.1    Ramchandani, S.2    Cervoni, N.3    Szyf, M.4
  • 4
    • 77649104794 scopus 로고    scopus 로고
    • Reprogramming towards pluripotency requires AID-dependent DNA demethylation
    • Bhutani N, Brady JJ, Damian M, Sacco A, Corbel SY, Blau HM. 2010. Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature 463: 1042-1047.
    • (2010) Nature , vol.463 , pp. 1042-1047
    • Bhutani, N.1    Brady, J.J.2    Damian, M.3    Sacco, A.4    Corbel, S.Y.5    Blau, H.M.6
  • 5
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. 2002. DNA methylation patterns and epigenetic memory. Genes Dev 16: 6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 6
    • 0037388165 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
    • Bransteitter R, Pham P, Scharff MD, Goodman MF. 2003. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc Natl Acad Sci 100: 4102-4107.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 4102-4107
    • Bransteitter, R.1    Pham, P.2    Scharff, M.D.3    Goodman, M.F.4
  • 7
    • 0037452080 scopus 로고    scopus 로고
    • Transcription-targeted DNA deamination by the AID antibody diversification enzyme
    • Chaudhuri J, Tian M, Khuong C, Chua K, Pinaud E, Alt FW. 2003. Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature 422: 726-730.
    • (2003) Nature , vol.422 , pp. 726-730
    • Chaudhuri, J.1    Tian, M.2    Khuong, C.3    Chua, K.4    Pinaud, E.5    Alt, F.W.6
  • 9
    • 50349093233 scopus 로고    scopus 로고
    • The AID/APOBEC family of nucleic acid mutators
    • Conticello SG. 2008. The AID/APOBEC family of nucleic acid mutators. Genome Biol 9: 229.
    • (2008) Genome Biol , vol.9 , pp. 229
    • Conticello, S.G.1
  • 11
    • 70350464349 scopus 로고    scopus 로고
    • A coming-of-age story: Activation-induced cytidine deaminase turns 10
    • Delker RK, Fugmann SD, Papavasiliou FN. 2009. A coming-of-age story: Activation-induced cytidine deaminase turns 10. Nat Immunol 10: 1147-1153.
    • (2009) Nat Immunol , vol.10 , pp. 1147-1153
    • Delker, R.K.1    Fugmann, S.D.2    Papavasiliou, F.N.3
  • 13
    • 0037561998 scopus 로고    scopus 로고
    • AID mediates hypermutation by deaminating single stranded DNA
    • Dickerson SK, Market E, Besmer E, Papavasiliou FN. 2003. AID mediates hypermutation by deaminating single stranded DNA. J Exp Med 197: 1291-1296.
    • (2003) J Exp Med , vol.197 , pp. 1291-1296
    • Dickerson, S.K.1    Market, E.2    Besmer, E.3    Papavasiliou, F.N.4
  • 14
    • 34250160167 scopus 로고    scopus 로고
    • Mechanisms regulating imprinted genes in clusters
    • Edwards CA, Ferguson-Smith AC. 2007. Mechanisms regulating imprinted genes in clusters. Curr Opin Cell Biol 19: 281-289.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 281-289
    • Edwards, C.A.1    Ferguson-Smith, A.C.2
  • 15
    • 77954661906 scopus 로고    scopus 로고
    • DNA hypomethylation in cancer cells
    • Ehrlich M. 2009. DNA hypomethylation in cancer cells. Epigenomics 1: 239-259.
    • (2009) Epigenomics , vol.1 , pp. 239-259
    • Ehrlich, M.1
  • 18
    • 0037068433 scopus 로고    scopus 로고
    • AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
    • Falnes PØ, Johansen RF, Seeberg E. 2002. AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli. Nature 419: 178-182.
    • (2002) Nature , vol.419 , pp. 178-182
    • Falnes, P.Ø.1    Johansen, R.F.2    Seeberg, E.3
  • 20
    • 33847625356 scopus 로고    scopus 로고
    • Base damage and single-strand break repair: Mechanisms and functional significance of short- and long-patch repair subpathways
    • Fortini P, Dogliotti E. 2007. Base damage and single-strand break repair: Mechanisms and functional significance of short- and long-patch repair subpathways. DNA Repair (Amst) 6: 398-409.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 398-409
    • Fortini, P.1    Dogliotti, E.2
  • 21
    • 73249144150 scopus 로고    scopus 로고
    • DNA methylation in early development
    • Geiman TM, Muegge K. 2010. DNA methylation in early development. Mol Reprod Dev 77: 105-113.
    • (2010) Mol Reprod Dev , vol.77 , pp. 105-113
    • Geiman, T.M.1    Muegge, K.2
  • 22
    • 15744401773 scopus 로고    scopus 로고
    • Eukaryotic cytosine methyltransferases
    • Goll MG, Bestor TH. 2005. Eukaryotic cytosine methyltransferases. Annu Rev Biochem 74: 481-514.
    • (2005) Annu Rev Biochem , vol.74 , pp. 481-514
    • Goll, M.G.1    Bestor, T.H.2
  • 24
    • 77954345408 scopus 로고    scopus 로고
    • Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway
    • Hajkova P, Jeffries SJ, Lee C, Miller N, Jackson SP, Surani MA. 2010. Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science 329: 78-82.
    • (2010) Science , vol.329 , pp. 78-82
    • Hajkova, P.1    Jeffries, S.J.2    Lee, C.3    Miller, N.4    Jackson, S.P.5    Surani, M.A.6
  • 25
    • 0038074420 scopus 로고    scopus 로고
    • The versatile thymine DNA-glycosylase: A comparative characterization of the human, Drosophila and fission yeast orthologs
    • Hardeland U, Bentele M, Jiricny J, Schar P. 2003. The versatile thymine DNA-glycosylase: A comparative characterization of the human, Drosophila and fission yeast orthologs. Nucleic Acids Res 31: 2261-2271.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2261-2271
    • Hardeland, U.1    Bentele, M.2    Jiricny, J.3    Schar, P.4
  • 27
    • 68049097008 scopus 로고    scopus 로고
    • Epigenetic dynamics of stem cells and cell lineage commitment: Digging Waddington's canal
    • Hemberger M, Dean W, Reik W. 2009. Epigenetic dynamics of stem cells and cell lineage commitment: Digging Waddington's canal. Nat Rev Mol Cell Biol 10: 526-537.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 526-537
    • Hemberger, M.1    Dean, W.2    Reik, W.3
  • 28
    • 67349255210 scopus 로고    scopus 로고
    • CpG islands - 'a rough guide.'
    • Illingworth RS, Bird AP. 2009. CpG islands - 'a rough guide.' FEBS Lett 583: 1713-1720.
    • (2009) FEBS Lett , vol.583 , pp. 1713-1720
    • Illingworth, R.S.1    Bird, A.P.2
  • 29
    • 77956189495 scopus 로고    scopus 로고
    • Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
    • Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y. 2010. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466: 1129-1133.
    • (2010) Nature , vol.466 , pp. 1129-1133
    • Ito, S.1    D'Alessio, A.C.2    Taranova, O.V.3    Hong, K.4    Sowers, L.C.5    Zhang, Y.6
  • 30
    • 41949136533 scopus 로고    scopus 로고
    • GADD45A does not promote DNA demethylation
    • doi: 10.1371/journal.pgen.1000013
    • Jin SG, Guo C, Pfeifer GP. 2008. GADD45A does not promote DNA demethylation. PLoS Genet 4: e1000013. doi: 10.1371/journal.pgen.1000013.
    • (2008) PLoS Genet , vol.4
    • Jin, S.G.1    Guo, C.2    Pfeifer, G.P.3
  • 33
    • 77953628087 scopus 로고    scopus 로고
    • Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels
    • doi: 10.1186/gb-2010-11-6-r63
    • Klug M, Heinz S, Gebhard C, Schwarzfischer L, Krause SW, Andreesen R, Rehli M. 2010. Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels. Genome Biol 11: R63. doi: 10.1186/gb-2010-11-6-r63.
    • (2010) Genome Biol , vol.11
    • Klug, M.1    Heinz, S.2    Gebhard, C.3    Schwarzfischer, L.4    Krause, S.W.5    Andreesen, R.6    Rehli, M.7
  • 34
    • 33746597375 scopus 로고    scopus 로고
    • Active cytosine demethylation triggered by a nuclear receptor involves DNA strand breaks
    • Kress C, Thomassin H, Grange T. 2006. Active cytosine demethylation triggered by a nuclear receptor involves DNA strand breaks. Proc Natl Acad Sci 103: 11112-11117.
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 11112-11117
    • Kress, C.1    Thomassin, H.2    Grange, T.3
  • 35
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • Kriaucionis S, Heintz N. 2009. The nuclear DNA base 5- hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324: 929-930.
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 36
    • 77249170184 scopus 로고    scopus 로고
    • Establishing, maintaining and modifying DNA methylation patterns in plants and animals
    • Law JA, Jacobsen SE. 2010. Establishing, maintaining and modifying DNA methylation patterns in plants and animals. Nat Rev Genet 11: 204-220.
    • (2010) Nat Rev Genet , vol.11 , pp. 204-220
    • Law, J.A.1    Jacobsen, S.E.2
  • 37
    • 71249101060 scopus 로고    scopus 로고
    • Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer
    • Lin C, Yang L, Tanasa B, Hutt K, Ju BG, Ohgi K, Zhang J, Rose DW, Fu XD, Glass CK, et al. 2009. Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell 139: 1069-1083.
    • (2009) Cell , vol.139 , pp. 1069-1083
    • Lin, C.1    Yang, L.2    Tanasa, B.3    Hutt, K.4    Ju, B.G.5    Ohgi, K.6    Zhang, J.7    Rose, D.W.8    Fu, X.D.9    Glass, C.K.10
  • 41
    • 38449122068 scopus 로고    scopus 로고
    • Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early development
    • Marr S, Morales H, Bottaro A, Cooper M, Flajnik M, Robert J. 2007. Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early development. J Immunol 179: 6783-6789.
    • (2007) J Immunol , vol.179 , pp. 6783-6789
    • Marr, S.1    Morales, H.2    Bottaro, A.3    Cooper, M.4    Flajnik, M.5    Robert, J.6
  • 47
    • 10644282845 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming
    • Morgan HD, Dean W, Coker HA, Reik W, Petersen-Mahrt SK. 2004. Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming. J Biol Chem 279: 52353-52360.
    • (2004) J Biol Chem , vol.279 , pp. 52353-52360
    • Morgan, H.D.1    Dean, W.2    Coker, H.A.3    Reik, W.4    Petersen-Mahrt, S.K.5
  • 48
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T. 2000. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102: 553-563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 49
    • 75749142980 scopus 로고    scopus 로고
    • A role for the elongator complex in zygotic paternal genome demethylation
    • Okada Y, Yamagata K, Hong K, Wakayama T, Zhang Y. 2010. A role for the elongator complex in zygotic paternal genome demethylation. Nature 463: 554-558.
    • (2010) Nature , vol.463 , pp. 554-558
    • Okada, Y.1    Yamagata, K.2    Hong, K.3    Wakayama, T.4    Zhang, Y.5
  • 51
    • 45449114804 scopus 로고    scopus 로고
    • The colorful history of active DNA demethylation
    • Ooi SK, Bestor TH. 2008. The colorful history of active DNA demethylation. Cell 133: 1145-1148.
    • (2008) Cell , vol.133 , pp. 1145-1148
    • Ooi, S.K.1    Bestor, T.H.2
  • 57
    • 0037019315 scopus 로고    scopus 로고
    • AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
    • Petersen-Mahrt SK, Harris RS, Neuberger MS. 2002. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 418: 99-103.
    • (2002) Nature , vol.418 , pp. 99-103
    • Petersen-Mahrt, S.K.1    Harris, R.S.2    Neuberger, M.S.3
  • 58
    • 77249148019 scopus 로고    scopus 로고
    • Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
    • Popp C, Dean W, Feng S, Cokus SJ, Andrews S, Pellegrini M, Jacobsen SE, Reik W. 2010. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 463: 1101-1105.
    • (2010) Nature , vol.463 , pp. 1101-1105
    • Popp, C.1    Dean, W.2    Feng, S.3    Cokus, S.J.4    Andrews, S.5    Pellegrini, M.6    Jacobsen, S.E.7    Reik, W.8
  • 59
    • 1542287213 scopus 로고    scopus 로고
    • A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex
    • Raghavan SC, Swanson PC, Wu X, Hsieh CL, Lieber MR. 2004. A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex. Nature 428: 88-93.
    • (2004) Nature , vol.428 , pp. 88-93
    • Raghavan, S.C.1    Swanson, P.C.2    Wu, X.3    Hsieh, C.L.4    Lieber, M.R.5
  • 60
    • 57649196594 scopus 로고    scopus 로고
    • DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
    • Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR. 2008. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 135: 1201-1212.
    • (2008) Cell , vol.135 , pp. 1201-1212
    • Rai, K.1    Huggins, I.J.2    James, S.R.3    Karpf, A.R.4    Jones, D.A.5    Cairns, B.R.6
  • 61
    • 0034625064 scopus 로고    scopus 로고
    • Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
    • Ramsahoye BH, Biniszkiewicz D, Lyko F, Clark V, Bird AP, Jaenisch R. 2000. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc Natl Acad Sci 97: 5237-5242.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 5237-5242
    • Ramsahoye, B.H.1    Biniszkiewicz, D.2    Lyko, F.3    Clark, V.4    Bird, A.P.5    Jaenisch, R.6
  • 62
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik W. 2007. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447: 425-432.
    • (2007) Nature , vol.447 , pp. 425-432
    • Reik, W.1
  • 65
    • 0034665756 scopus 로고    scopus 로고
    • X inactivation in the mouse embryo deficient for Dnmt1: Distinct effect of hypomethylation on imprinted and random X inactivation
    • Sado T, Fenner MH, Tan SS, Tam P, Shioda T, Li E. 2000. X inactivation in the mouse embryo deficient for Dnmt1: Distinct effect of hypomethylation on imprinted and random X inactivation. Dev Biol 225: 294-303.
    • (2000) Dev Biol , vol.225 , pp. 294-303
    • Sado, T.1    Fenner, M.H.2    Tan, S.S.3    Tam, P.4    Shioda, T.5    Li, E.6
  • 66
    • 66049129496 scopus 로고    scopus 로고
    • The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription
    • Shen HM, Poirier MG, Allen MJ, North J, Lal R, Widom J, Storb U. 2009. The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription. J Exp Med 206: 1057-1071.
    • (2009) J Exp Med , vol.206 , pp. 1057-1071
    • Shen, H.M.1    Poirier, M.G.2    Allen, M.J.3    North, J.4    Lal, R.5    Widom, J.6    Storb, U.7
  • 67
    • 5444238192 scopus 로고    scopus 로고
    • DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei
    • Simonsson S, Gurdon J. 2004. DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei. Nat Cell Biol 6: 984-990.
    • (2004) Nat Cell Biol , vol.6 , pp. 984-990
    • Simonsson, S.1    Gurdon, J.2
  • 68
    • 42649123314 scopus 로고    scopus 로고
    • Mechanism and regulation of class switch recombination
    • Stavnezer J, Guikema JE, Schrader CE. 2008. Mechanism and regulation of class switch recombination. Annu Rev Immunol 26: 261-292.
    • (2008) Annu Rev Immunol , vol.26 , pp. 261-292
    • Stavnezer, J.1    Guikema, J.E.2    Schrader, C.E.3
  • 70
    • 0037068446 scopus 로고    scopus 로고
    • Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage
    • Trewick SC, Henshaw TF, Hausinger RP, Lindahl T, Sedgwick B. 2002. Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage. Nature 419: 174-178.
    • (2002) Nature , vol.419 , pp. 174-178
    • Trewick, S.C.1    Henshaw, T.F.2    Hausinger, R.P.3    Lindahl, T.4    Sedgwick, B.5
  • 71
    • 0031662164 scopus 로고    scopus 로고
    • Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
    • Walsh CP, Chaillet JR, Bestor TH. 1998. Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat Genet 20: 116-117.
    • (1998) Nat Genet , vol.20 , pp. 116-117
    • Walsh, C.P.1    Chaillet, J.R.2    Bestor, T.H.3
  • 72
    • 77953466536 scopus 로고    scopus 로고
    • Nuclear reprogramming to a pluripotent state by three approaches
    • Yamanaka S, Blau HM. 2010. Nuclear reprogramming to a pluripotent state by three approaches. Nature 465: 704-712.
    • (2010) Nature , vol.465 , pp. 704-712
    • Yamanaka, S.1    Blau, H.M.2
  • 73
    • 73349104113 scopus 로고    scopus 로고
    • Active DNA demethylation mediated by DNA glycosylases
    • Zhu JK. 2009. Active DNA demethylation mediated by DNA glycosylases. Annu Rev Genet 43: 143-166.
    • (2009) Annu Rev Genet , vol.43 , pp. 143-166
    • Zhu, J.K.1
  • 74
    • 0034326849 scopus 로고    scopus 로고
    • 5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence
    • Zhu B, Zheng Y, Angliker H, Schwarz S, Thiry S, Siegmann M, Jost JP. 2000. 5-Methylcytosine DNA glycosylase activity is also present in the human MBD4 (G/T mismatch glycosylase) and in a related avian sequence. Nucleic Acids Res 28: 4157-4165.
    • (2000) Nucleic Acids Res , vol.28 , pp. 4157-4165
    • Zhu, B.1    Zheng, Y.2    Angliker, H.3    Schwarz, S.4    Thiry, S.5    Siegmann, M.6    Jost, J.P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.