Anti-inflammatory properties of fruit juices enriched with pine bark extract in an in vitro model of inflamed human intestinal epithelium: The effect of gastrointestinal digestion

Food and Chemical Toxicology

Volumn 53, Issue , 2013, Pages 94-99

  Frontela Saseta, Carmen ^a   López Nicolás, Rubén ^a   González Bermúdez, Carlos A ^a   Martínez Graciá, Carmen ^a   Ros Berruezo, Gaspar ^a  

^a UNIVERSITY OF MURCIA   (Spain)

Author keywords

Fruit juices; Gut inflammation; In vitro digestion; Pine bark extract

Indexed keywords

ANTIINFLAMMATORY AGENT; BACTERIUM LIPOPOLYSACCHARIDE; CAFFEIC ACID; CHLOROGENIC ACID; FERULIC ACID; GALLIC ACID; INTERLEUKIN 8; NITRIC OXIDE; PINE BARK EXTRACT; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; TAXIFOLIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BARK; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIGESTION; DRUG DETERMINATION; DRUG ISOLATION; ENTERITIS; FEMALE; FOOD COMPOSITION; FRUIT JUICE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INFLAMMATORY CELL; INTESTINE EPITHELIUM; INTESTINE MUCOSA PERMEABILITY; MACROPHAGE; NONHUMAN; PHYTOCHEMISTRY; PINE; RED FRUIT JUICE;

ANANAS; ANIMALS; ANTI-INFLAMMATORY AGENTS; BEVERAGES; CACO-2 CELLS; DIGESTION; FRUIT; HUMANS; INFLAMMATION; INTERLEUKIN-8; INTESTINAL MUCOSA; MALE; MICE; NITRIC OXIDE; PINUS; PLANT BARK; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES;

ANANAS COMOSUS;

EID: 84871596516     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.11.024     Document Type: Article

References (36)

1. Bermúdez-Soto M.J., Tomas-Barberán F.A. Evaluation of commercial red fruit juice concentrates as ingredients for antioxidant functional juices. Eur. Food Res. Technol. 2004, 219:133-141.
2. Bermúdez-Soto M.J., Tomás-Barberán F.A., García-Conesa M.T. Stability of polyphenols in chokeberry (Aroniamelanocarpa) subjected to in vitro gastric and pancreatic digestion. Food Chem. 2007, 102:865-874.
3. Boato F., Wortley G.M., Liu R.H., Glahn R.P. Red grape juice inhibits iron availability: Application of an in vitro digestion/Caco-2 cell model. J. Agric. FoodChem. 2002, 50:6935-6938.
4. Bode A.M., Dong Z. Targeting signal transduction pathways by chemopreventive agents. Mutat. Res. 2004, 555:33-51.
5. Breithpaut D.E. Determination of folic acid by ion-pair RP-HPLC in vitamin-fortified fruit juices after solid-phase extraction. Food Chem. 2001, 74:521-525.
6. Chen X.M., Kitts D.D. Antioxidant and anti-inflammatory activities of Maillard reaction products isolated from sugar-aminoacid model systems. J. Agric. Food Chem. 2011, 59:11294-11303.
7. Conner E.M., Grisham M.B. Inflammation, free radicals, and antioxidants. Nutrition 1996, 12:274-277.
8. D'Andrea G. Pycnogenol: a blend of procyanidins with multifaceted therapeutic applications?. Fitoterapia 2010, 81:724-736.
9. Davies M.G., Hagen P.O. Systemic inflammatory response syndrome. Br. J. Surg. 1997, 84:920-935.
10. Evans D.A., Hirsch J.B., Dushenkov S. Phenolics, inflammation and nutrigenomics. J. Sci. Food Agric. 2006, 86:2503-2509.
11. Ferguson L.R., Shelling A.N., Browning B.L., Huebner C., Petermann I. Genes, diet and inflammatory bowel disease. Mutat. Res-Fund. Mol. M. 2007, 622:70-83.
12. Fiocchi C. More answers and more questions in inflammatory bowel disease. Curr. Opin. Gastroenterol. 2003, 19:325-326.
13. Frontela C., Ros G., Martinez C., Sanchez-Siles L.M., Canali R., Virgili F. Stability of Pycnogenol ® as aningredient in fruitjuicessubjectedtoin vitro gastrointestinal digestion. J. Sci. FoodAgric. 2011, 91:286-292.
14. Frontela-Saseta C., López-Nicolás R., González-Bermúdez C.A., Peso-Echarri P., Ros-Berruezo G., Martínez-Graciá C., Canali R., Virgili F. Evaluation of antioxidant activity and antiproliferative effect of fruit juices enriched with pycnogenol ® in colon carcinoma cells. the effect of in vitro gastrointestinal digestion. Phytother. Res. 2011, 25:1870-1875.
15. Gauliard B., Grieve D., Wilson R., Crozier A., Jekins C., Muller W., Lean M. The effect of dietary phenolic compounds on cytokine and antioxidant production by A549 cells. J. Med. Food 2008, 11:382-384.
16. Hashimoto K., Kawagishi H., Nakayama T., Shimizu M. Effect of capsianoside, a diterpeneglycoside, onthight-junctionalpermeability. BBA-Biomemb. 1997, 1323:281-290.
17. Javanmardi J., Stushnoff C., Locke E., Vivanco J.M. Antioxidantactivity and total phenoliccontent of Iranian Ocimumaccessions. Food Chem. 2003, 83:547-550.
18. Kahkonen M.P., Hopia A.I., Vuorela H.J., Rauha J.P., Pihlaja K., Kujala T.S., Heinonen M. Antioxidantactivity of plant extracts containing phenolic compounds. J. Agric. Food Chem. 1999, 47:3954-3962.
19. Kim H., Kong H., Choi B., Yang Y., Kim Y., Lim M.J., Neckers L., Jung Y. Metabolic and pharmacological properties of rutin, a dietary quercetin glycoside, for treatment of inflammatory bowel disease. Pharm. Res. 2005, 22:1499-1509.
20. Lichtenthaler R., Marx F. Total oxidant scavenging capacities of common European fruit and vegetable juices. J. Agric. Food Chem. 2005, 53:103-110.
21. Maimoona A., Naeem I., Saddiqe Z., Jameel K. A review on biological, nutraceutical and clinical aspects of French maritime pine bark extract. J. Ethnopharmacol. 2010, 133:261-277.
22. Manach C., Scalbert A., Morand C., Renesy C., Jimenez L. Polyphenols: food sources and bioavailability. Am. J. Clin. Nutr. 2004, 79:727-747.
23. Miguel M.G. Antioxidant and anti-inflammatory activities of essential oils: a short review. Molecules 2010, 15:9252-9287.
24. Naik E., Dixit V.M. Mitochondrial reactive oxygen species drive proinflamatory cytokine production. J. E. M. 2011, 3:417-420.
25. Nanthakumar N.M., Furunyan R.D., Sanderson I., Walker W.A. Inflammation in the developing human intestine: a possible pathophysiologic contribution to necrotizing enterocolitis. PNAS 2000, 97:6043-6048.
26. Narai A., Arai S., Shimizu M. Rapid decrease in transepithelial electrical resistance of human intestinal Caco-2 cell monolayers by cytotoxic membrane perturbents. Toxicol. In Vitro. 1997, 11:347-354.
27. Nishitani Y., Mizuno M. Anti-inflammatory activities of Lactococcuslactis subsp. Cremoris FC in in vitro and in vivo gut inflammation models. Biosci. Microflora 2010, 29:169-178.
28. Paradkar P.N., Blum P.S., Berhow M.A., Baumann H., Kuo S.M. Dietary isoflavones suppress endotoxin-induced inflammatory reaction in liver and intestine. Cancer Lett. 2004, 215:21-28.
29. Romier B., Van De Walle J., During A., Larondelle Y., Schneider Y.J. Modulation of signaling NF-kB activation pathway by polyphenols in human intestinal Caco-2 cells. Br. J. Nutr. 2008, 100:542-551.
30. Romier-Crouzet B., Van De Walle J., During A., Joly A., Rousseau C. Inhibition of inflammatory mediators by polyphenolic plant extracts in human intestinal Caco-2 cells. Food Chem. Toxicol. 2009, 47:1221-1230.
31. Ruiz P.A., Haller D. Functional diversity of flavonoids in the inhibition of the proinflammatory NF-kB, IRF, and Akt signaling pathways in murine intestinal epithelial cells. J. Nutr. 2006, 136:664-671.
32. Sergent T., Piront N., Meurice J., Toussaint O., Schneider Y. Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium. Chem. Biol. Interact. 2010, 188:659-667.
33. Singleton V.L., Rossi J.A. Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am. J. Enol. Vitic. 1965, 16:144-158.
34. Tanoue T., Nishitani Y., Kanazawa K., Hashimoto T., Mizuno M. In vitro model to estimate gut inflammation using co-cultured caco-2 and RAW 264.7 cells. Biochem. Bio. Phys. Res. Commun. 2008, 374:565-569.
35. Waldner M., Neurath M. Novel cytokine-targeted therapies and intestinal inflammation. Curr. Opin. Pharmacol. 2009, 9:702-707.
36. Yoon J.H., Beak S.J. Molecular targets of dietary polyphenols with anti-inflammatory properties. Yonsei Med. J. 2005, 46:585-596.