Increasing the dynamic control space of mammalian transcription devices by combinatorial assembly of homologous regulatory elements from different bacterial species

Metabolic Engineering

Volumn 15, Issue 1, 2013, Pages 144-150

  Bacchus, William ^a   Weber, Wilfried ^a,b   Fussenegger, Martin ^a,c  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Chlamydia; Combinatorial gene expression; Gene regulation; L tryptophan; Synthetic biology

Indexed keywords

BACKGROUND NOISE; BACTERIAL SPECIES; BIOTECHNOLOGICAL APPLICATIONS; BUILDING BLOCKES; CHIMERIC PROMOTERS; CHLAMYDIA; CHLAMYDIA TRACHOMATIS; COMBINATORIAL ASSEMBLY; COREPRESSORS; DYNAMIC CONTROLS; E. COLI; GENE EXPRESSION LEVELS; GENETIC CIRCUITS; GENETIC EXPRESSIONS; HERPES SIMPLEX VIRUS; L-TRYPTOPHAN; MAMMALIAN CELLS; REGULATORY CIRCUITS; REGULATORY ELEMENTS; REGULATORY MECHANISM; REGULATORY SYSTEMS; SYNTHETIC BIOLOGY; SYSTEMS APPROACH; TRANSACTIVATION; TRANSACTIVATION DOMAIN; TRANSACTIVATORS; TRANSCRIPTIONAL REPRESSORS;

AMINO ACIDS; BIOCHEMISTRY; ESCHERICHIA COLI; GENE EXPRESSION; MAMMALS; TRANSCRIPTION; TRANSCRIPTION FACTORS; VIRUSES;

BACTERIA;

TRYPTOPHAN;

ARTICLE; BIOSYNTHESIS; CHLAMYDIA TRACHOMATIS; ESCHERICHIA COLI; GENE EXPRESSION; GENETIC TRANSCRIPTION; HERPES SIMPLEX VIRUS; MOLECULAR DYNAMICS; NOISE; NONHUMAN; OPERON; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

ANIMALS; CHLAMYDIA TRACHOMATIS; ESCHERICHIA COLI; HUMANS; PROMOTER REGIONS, GENETIC; REGULATORY ELEMENTS, TRANSCRIPTIONAL; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRYPTOPHAN;

BACTERIA (MICROORGANISMS); CHLAMYDIA; CHLAMYDIA TRACHOMATIS; ESCHERICHIA COLI; EUKARYOTA; MAMMALIA; PROKARYOTA; SIMPLEXVIRUS;

EID: 84871442897     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2012.11.003     Document Type: Article

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