Inactivation of patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfr but not kit

Gastroenterology

Volumn 144, Issue 1, 2013, Pages

  Pelczar, Penelope ^a   Zibat, Arne ^a   Van Dop, Willemijn A ^b   Heijmans, Jarom ^b   Bleckmann, Annalen ^a   Gruber, Wolfgang ^c   Nitzki, Frauke ^a   Uhmann, Anja ^a   Guijarro, Maria V ^d   Hernando, Eva ^d   Dittmann, Kai ^a   Wienands, Jürgen ^a   Dressel, Ralf ^a   Wojnowski, Leszek ^e   Binder, Claudia ^a   Taguchi, Takahiro ^f   Beissbarth, Tim ^a   Hogendoorn, Pancras C W ^g   Antonescu, Cristina R ^h   Rubin, Brian P ⁱ   Schulz Schaeffer, Walter ^a   Aberger, Fritz ^c   Van Den Brink, Gijs R ^b   Hahn, Heidi ^a   more..

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF SALZBURG   (Austria)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e JOHANNES GUTENBERG UNIVERSITY   (Germany)

^f KOCHI UNIVERSITY   (Japan)

^g LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^h MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

ⁱ TAUSSIG CANCER INSTITUTE   (United States)

Author keywords

Active Hh Cascade; GIST Mouse Model; Pdgfr Signaling Cascade; Ptch Mutation

Indexed keywords

AGAR; CRE RECOMBINASE; IMATINIB; LYSOZYME; PLATELET DERIVED GROWTH FACTOR A; PROTEIN PATCHED 1; STEM CELL FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL LINEAGE; CELL PROLIFERATION; CONTROLLED STUDY; GASTROINTESTINAL STROMAL TUMOR; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LEYDIG CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 84871345301     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.09.061     Document Type: Article

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