The c-Kit/D816V mutation eliminates the differences in signal transduction and biological responses between two isoforms of c-Kit

Cellular Signalling

Volumn 21, Issue 3, 2009, Pages 413-418

  Pedersen, M ^a   Ronnstrand L ^a   Sun, J ^a  

^a Malmö University Hospital   (Sweden)

Author keywords

Acute myeloid leukemia; c Kit D816V; Isoform; Mutation

Indexed keywords

ASPARAGINE; CBL PROTEIN; GLYCINE; LYSINE; PROTEIN SHC; PROTEIN TYROSINE PHOSPHATASE SHP 2; STEM CELL FACTOR RECEPTOR; VALINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; GENE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WILD TYPE;

ALTERNATIVE SPLICING; AMINO ACIDS; ANIMALS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION REGULATION, NEOPLASTIC; MICE; MUTATION; PRECURSOR CELLS, B-LYMPHOID; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-KIT; SIGNAL TRANSDUCTION; STEM CELL FACTOR; TRANSFECTION;

EID: 58249134128     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2008.11.008     Document Type: Article

References (40)

1. Blume-Jensen P., Claesson-Welsh L., Siegbahn A., Zsebo K.M., Westermark B., and Heldin C.H. EMBO J. 10 13 (1991) 4121
2. Lennartsson J., and Rönnstrand L. Current Cancer Drug Targets 6 1 (2006) 65
3. Hayashi S., Kunisada T., Ogawa M., Yamaguchi K., and Nishikawa S. Nucleic Acids Res. 19 6 (1991) 1267
4. Reith A.D., Ellis C., Lyman S.D., Anderson D.M., Williams D.E., Bernstein A., and Pawson T. EMBO J. 10 9 (1991) 2451
5. Crosier P.S., Ricciardi S.T., Hall L.R., Vitas M.R., Clark S.C., and Crosier K.E. Blood 82 4 (1993) 1151
6. Theou N., Tabone S., Saffroy R., Le Cesne A., Julie C., Cortez A., Lavergne-Slove A., Debuire B., Lemoine A., and Emile J.F. Biochim. Biophys. Acta 1688 3 (2004) 250
7. Voytyuk O., Lennartsson J., Mogi A., Caruana G., Courtneidge S., Ashman L.K., and Rönnstrand L. J. Biol. Chem. 278 11 (2003) 9159
8. Caruana G., Cambareri A.C., and Ashman L.K. Oncogene 18 40 (1999) 5573
9. Sun J., Pedersen M., and Rönnstrand L. J. Biol. Chem. 283 41 (2008) 27444
10. Hirota S., Isozaki K., Moriyama Y., Hashimoto K., Nishida T., Ishiguro S., Kawano K., Hanada M., Kurata A., Takeda M., Muhammad Tunio G., Matsuzawa Y., Kanakura Y., Shinomura Y., and Kitamura Y. Science 279 5350 (1998) 577
11. Hornick J.L., and Fletcher C.D. Human Pathol. 38 5 (2007) 679
12. Antonescu C.R., Busam K.J., Francone T.D., Wong G.C., Guo T., Agaram N.P., Besmer P., Jungbluth A., Gimbel M., Chen C.T., Veach D., Clarkson B.D., Paty P.B., and Weiser M.R. Int. J. Cancer 121 2 (2007) 257
13. Corbacioglu S., Kilic M., Westhoff M.A., Reinhardt D., Fulda S., and Debatin K.M. Blood 108 10 (2006) 3504
14. Nagata H., Worobec A.S., Oh C.K., Chowdhury B.A., Tannenbaum S., Suzuki Y., and Metcalfe D.D. Proc. Natl. Acad. Sci. U. S. A. 92 23 (1995) 10560
15. Furitsu T., Tsujimura T., Tono T., Ikeda H., Kitayama H., Koshimizu U., Sugahara H., Butterfield J.H., Ashman L.K., Kanayama Y., et al. J. Clin. Invest. 92 4 (1993) 1736
16. Schnittger S., Kohl T.M., Haferlach T., Kern W., Hiddemann W., Spiekermann K., and Schoch C. Blood 107 5 (2006) 1791
17. Tan A., Westerman D., McArthur G.A., Lynch K., Waring P., and Dobrovic A. Clin. Chem. 52 12 (2006) 2250
18. Biermann K., Goke F., Nettersheim D., Eckert D., Zhou H., Kahl P., Gashaw I., Schorle H., and Büttner R. J. Pathol. 213 3 (2007) 311
19. Tian Q., Frierson Jr. H.F., Krystal G.W., and Moskaluk C.A. Am. J. Pathol. 154 6 (1999) 1643
20. Voisset E., Lopez S., Dubreuil P., and De Sepulveda P. Blood 110 7 (2007) 2593
21. Jelacic T., and Linnekin D. Blood 105 5 (2005) 1923
22. Sakuma Y., Sakurai S., Oguni S., Hironaka M., and Saito K. Cancer Sci. 94 6 (2003) 486
23. Guerrini F., Galimberti S., Ciabatti E., Brizzi S., Testi R., Pollastrini A., Falini B., and Petrini M. Leukemia 21 9 (2007) 2056
24. Lennartsson J., Blume-Jensen P., Hermanson M., Pontén E., Carlberg M., and Rönnstrand L. Oncogene 18 40 (1999) 5546
25. Dorsey J.F., Cunnick J.M., Mane S.M., and Wu J. Blood 99 4 (2002) 1388
26. Tauchi T., Feng G.S., Marshall M.S., Shen R., Mantel C., Pawson T., and Broxmeyer H.E. J. Biol. Chem. 269 40 (1994) 25206
27. Moriyama Y., Tsujimura T., Hashimoto K., Morimoto M., Kitayama H., Matsuzawa, Kitamura Y., and Kanakura Y. J. Biol. Chem. 271 7 (1996) 3347
28. Xiang Z., Kreisel F., Cain J., Colson A., and Tomasson M.H. Mol. Cell. Biol. 27 1 (2007) 267
29. Lavagna C., Marchetto S., Birnbaum D., and Rosnet O. J. Biol. Chem. 270 7 (1995) 3165
30. Kwong K.Y., and Hung M.C. Mol. Carcinog. 23 2 (1998) 62
31. Bell C.A., Tynan J.A., Hart K.C., Meyer A.N., Robertson S.C., and Donoghue D.J. Mol. Biol. Cell. 11 10 (2000) 3589
32. Schittenhelm M.M., Shiraga S., Schroeder A., Corbin A.S., Griffith D., Lee F.Y., Bokemeyer C., Deininger M.W., Druker B.J., and Heinrich M.C. Cancer Res. 66 1 (2006) 473
33. Shah N.P., Lee F.Y., Luo R., Jiang Y., Donker M., and Akin C. Blood 108 1 (2006) 286
34. Gleixner K.V., Mayerhofer M., Sonneck K., Gruze A., Samorapoompichit P., Baumgartner C., Lee F.Y., Aichberger K.J., Manley P.W., Fabbro D., Pickl W.F., Sillaber C., and Valent P. Haematologica 92 11 (2007) 1451
35. Masson K., Heiss E., Band H., and Rönnstrand L. Biochem. J. 399 1 (2006) 59
36. Harir N., Boudot C., Friedbichler K., Sonneck K., Kondo R., Martin-Lanneree S., Kenner L., Kerenyi M., Yahiaoui S., Gouilleux-Gruart V., Gondry J., Benit L., Dusanter-Fourt I., Lassoued K., Valent P., Moriggl R., and Gouilleux F. Blood 112 6 (2008) 2463
37. Ekerot M., Stavridis M.P., Delavaine L., Mitchell M.P., Staples C., Owens D.M., Keenan I.D., Dickinson R.J., Storey K.G., and Keyse S.M. Biochem. J. 412 2 (2008) 287
38. Yuzawa S., Opatowsky Y., Zhang Z., Mandiyan V., Lax I., and Schlessinger J. Cell 130 2 (2007) 323
39. Mol C.D., Dougan D.R., Schneider T.R., Skene R.J., Kraus M.L., Scheibe D.N., Snell G.P., Zou H., Sang B.C., and Wilson K.P. J. Biol. Chem. 279 30 (2004) 31655
40. Vaudry D., Stork P.J., Lazarovici P., and Eiden L.E. Science 296 5573 (2002) 1648