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Volumn 18, Issue 4, 2013, Pages 386-399

P53 orchestrates the PGC-1α-mediated antioxidant response upon mild redox and metabolic imbalance

Author keywords

[No Author keywords available]

Indexed keywords

6 ANILINO 5,8 QUINOLINEQUINONE; CYCLIC GMP; GLUTATHIONE; GUANYLATE CYCLASE; MANGANESE SUPEROXIDE DISMUTASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN P53;

EID: 84871320315     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2012.4615     Document Type: Article
Times cited : (167)

References (49)
  • 1
    • 79953131110 scopus 로고    scopus 로고
    • Nitric oxide is the primary mediator of cytotoxicity induced by GSH depletion in neuronal cells
    • Aquilano K, Baldelli S, Cardaci S, Rotilio G, and Ciriolo MR. Nitric oxide is the primary mediator of cytotoxicity induced by GSH depletion in neuronal cells. J Cell Sci 124: 1043-1054, 2011.
    • (2011) J Cell Sci , vol.124 , pp. 1043-1054
    • Aquilano, K.1    Baldelli, S.2    Cardaci, S.3    Rotilio, G.4    Ciriolo, M.R.5
  • 2
    • 77954353059 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: Possible direct function in mitochondrial biogenesis
    • Aquilano K, Vigilanza P, Baldelli S, Pagliei B, Rotilio G, and Ciriolo MR. Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis. J Biol Chem 285: 21590-21599, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 21590-21599
    • Aquilano, K.1    Vigilanza, P.2    Baldelli, S.3    Pagliei, B.4    Rotilio, G.5    Ciriolo, M.R.6
  • 3
    • 33845602614 scopus 로고    scopus 로고
    • Mi-tochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: A rationale for the redundancy of SOD1
    • Aquilano K, Vigilanza P, Rotilio G, and Ciriolo MR. Mi-tochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1. FASEB J 20: 1683-1685, 2006.
    • (2006) FASEB J , vol.20 , pp. 1683-1685
    • Aquilano, K.1    Vigilanza, P.2    Rotilio, G.3    Ciriolo, M.R.4
  • 4
    • 48349092316 scopus 로고    scopus 로고
    • Glu-tathione and copper, zinc superoxide dismutase are modulated by overexpression of neuronal nitric oxide synthase
    • Baldelli S, Aquilano K, Rotilio G, and Ciriolo MR. Glu-tathione and copper, zinc superoxide dismutase are modulated by overexpression of neuronal nitric oxide synthase. Int J Biochem Cell Biol 40: 2660-2670, 2008.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 2660-2670
    • Baldelli, S.1    Aquilano, K.2    Rotilio, G.3    Ciriolo, M.R.4
  • 5
    • 78650233501 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression
    • Baldelli S, Aquilano K, Rotilio G, and Ciriolo MR. Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression. Int J Biochem Cell Biol 43: 163-169, 2011.
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 163-169
    • Baldelli, S.1    Aquilano, K.2    Rotilio, G.3    Ciriolo, M.R.4
  • 6
    • 62249096975 scopus 로고    scopus 로고
    • Glutathione dysregulation and the etiology and progression of human diseases
    • Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, and Hammond CL. Glutathione dysregulation and the etiology and progression of human diseases. Biol Chem 390: 191-214, 2009.
    • (2009) Biol Chem , vol.390 , pp. 191-214
    • Ballatori, N.1    Krance, S.M.2    Notenboom, S.3    Shi, S.4    Tieu, K.5    Hammond, C.L.6
  • 7
    • 34249681337 scopus 로고    scopus 로고
    • P53: New roles in metabolism
    • Bensaad K and Vousden KH. p53: new roles in metabolism. Trends Cell Biol 17: 286-291, 2007.
    • (2007) Trends Cell Biol , vol.17 , pp. 286-291
    • Bensaad, K.1    Vousden, K.H.2
  • 8
    • 33845670719 scopus 로고    scopus 로고
    • Nitric oxide regulates mitochondrial oxidative stress protection via the transcriptional coactivator PGC-1alpha
    • Borniquel S, Valle I, Cadenas S, Lamas S, and Monsalve M. Nitric oxide regulates mitochondrial oxidative stress protection via the transcriptional coactivator PGC-1alpha. FASEB J 20: 1889-1891, 2006.
    • (2006) FASEB J , vol.20 , pp. 1889-1891
    • Borniquel, S.1    Valle, I.2    Cadenas, S.3    Lamas, S.4    Monsalve, M.5
  • 9
    • 0030855899 scopus 로고    scopus 로고
    • Spontaneous Mutation Frequencies and Spectra in P53 (++) and P53 (-) Mice: A Test of the 'guardian of the genome' hypothesis in the Big Blue transgenic mouse mutation detection system
    • Buettner VL, Nishino H, Haavik J, Knoll A, Hill K, and Sommer SS. Spontaneous mutation frequencies and spectra in p53 (+/+) and p53 (-/-) mice: a test of the 'guardian of the genome' hypothesis in the Big Blue transgenic mouse mutation detection system. Mutat Res 379: 13-20, 1997.
    • (1997) Mutat Res , vol.379 , pp. 13-20
    • Buettner, V.L.1    Nishino, H.2    Haavik, J.3    Knoll, A.4    Hill, K.5    Sommer, S.S.6
  • 10
    • 58849090439 scopus 로고    scopus 로고
    • Transcribe to survive: Transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease
    • Clark J and Simon DK. Transcribe to survive: transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease. Antioxid Redox Signal 11: 509-528, 2009.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 509-528
    • Clark, J.1    Simon, D.K.2
  • 11
    • 0037342151 scopus 로고    scopus 로고
    • Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR
    • Daitoku H, Yamagata K, Matsuzaki H, Hatta M, and Fu-kamizu A. Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR. Diabetes 52: 642-649, 2003.
    • (2003) Diabetes , vol.52 , pp. 642-649
    • Daitoku, H.1    Yamagata, K.2    Matsuzaki, H.3    Hatta, M.4    Fu-Kamizu, A.5
  • 13
    • 79961199862 scopus 로고    scopus 로고
    • Redox control and interplay between p53 isoforms: Roles in the regulation of basal p53 levels, cell fate and senescence
    • Hafsi H and Hainaut P. Redox control and interplay between p53 isoforms: roles in the regulation of basal p53 levels, cell fate and senescence. Antioxid Redox Signal 15: 1655-1667, 2011.
    • (2011) Antioxid Redox Signal , vol.15 , pp. 1655-1667
    • Hafsi, H.1    Hainaut, P.2
  • 15
    • 33845596500 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
    • Handschin C and Spiegelman BM. Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. Endocr Rev 27: 728-735, 2006.
    • (2006) Endocr Rev , vol.27 , pp. 728-735
    • Handschin, C.1    Spiegelman, B.M.2
  • 16
    • 78149361937 scopus 로고    scopus 로고
    • Manganese superoxide dismutase vs. p53: Regulation of mitochondrial ROS
    • Holley AK, Dhar SK, and St. Clair DK. Manganese superoxide dismutase vs. p53: regulation of mitochondrial ROS. Mitochondrion 10: 649-661, 2010.
    • (2010) Mitochondrion , vol.10 , pp. 649-661
    • Holley, A.K.1    Dhar, S.K.2    St. Clair, D.K.3
  • 18
    • 3843114956 scopus 로고    scopus 로고
    • Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation
    • Im H, Grass JA, Johnson KD, Boyer ME, Wu J, and Bresnick EH. Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation. Methods Mol Biol 284: 129-146, 2004.
    • (2004) Methods Mol Biol , vol.284 , pp. 129-146
    • Im, H.1    Grass, J.A.2    Johnson, K.D.3    Boyer, M.E.4    Wu, J.5    Bresnick, E.H.6
  • 19
    • 58349095060 scopus 로고    scopus 로고
    • AMP-activated protein kinase-regulated activation of the PGC-1alpha promoter in skeletal muscle cells
    • Irrcher I, Ljubicic V, Kirwan AF, and Hood DA. AMP-activated protein kinase-regulated activation of the PGC-1alpha promoter in skeletal muscle cells. PLoS One 3: e3614, 2008.
    • (2008) PLoS One , vol.3
    • Irrcher, I.1    Ljubicic, V.2    Kirwan, A.F.3    Hood, D.A.4
  • 20
    • 0037507247 scopus 로고    scopus 로고
    • P53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways
    • Komarova EA, Neznanov N, Komarov PG, Chernov MV, Wang K, and Gudkov AV. p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways. J Biol Chem 278: 15465-15468, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 15465-15468
    • Komarova, E.A.1    Neznanov, N.2    Komarov, P.G.3    Chernov, M.V.4    Wang, K.5    Gudkov, A.V.6
  • 21
    • 33750544319 scopus 로고    scopus 로고
    • Glu-tathione peroxidase 1 and a high cellular glutathione concentration are essential for effective organic hydroperoxide detoxification in astrocytes
    • Liddell JR, Dringen R, Crack PJ, and Robinson SR. Glu-tathione peroxidase 1 and a high cellular glutathione concentration are essential for effective organic hydroperoxide detoxification in astrocytes. Glia 54: 873-879, 2006.
    • (2006) Glia , vol.54 , pp. 873-879
    • Liddell, J.R.1    Dringen, R.2    Crack, P.J.3    Robinson, S.R.4
  • 22
    • 3242686012 scopus 로고    scopus 로고
    • Glu-tathione metabolism during aging and in Alzheimer disease
    • Liu H, Wang H, Shenvi S, Hagen TM, and Liu RM. Glu-tathione metabolism during aging and in Alzheimer disease. Ann N Y Acad Sci 1019: 346-349, 2004.
    • (2004) Ann N y Acad Sci , vol.1019 , pp. 346-349
    • Liu, H.1    Wang, H.2    Shenvi, S.3    Hagen, T.M.4    Liu, R.M.5
  • 23
    • 34250706879 scopus 로고    scopus 로고
    • Nitric oxide stimulates heme oxygenase-1 gene transcription via the Nrf2/ARE complex to promote vascular smooth muscle cell survival
    • Liu XM, Peyton KJ, Ensenat D, Wang H, Hannink M, Alam J, and Durante W. Nitric oxide stimulates heme oxygenase-1 gene transcription via the Nrf2/ARE complex to promote vascular smooth muscle cell survival. Cardiovasc Res 75: 381-389, 2007.
    • (2007) Cardiovasc Res , vol.75 , pp. 381-389
    • Liu, X.M.1    Peyton, K.J.2    Ensenat, D.3    Wang, H.4    Hannink, M.5    Alam, J.6    Durante, W.7
  • 29
    • 62349134367 scopus 로고    scopus 로고
    • Inhibition of non-small cell lung cancer cell migration by grape seed proanthocyanidins is mediated through the inhibition of nitric oxide, guanylate cyclase, and ERK1/2
    • Punathil T and Katiyar SK. Inhibition of non-small cell lung cancer cell migration by grape seed proanthocyanidins is mediated through the inhibition of nitric oxide, guanylate cyclase, and ERK1/2. Mol Carcinog 48: 232-242, 2009.
    • (2009) Mol Carcinog , vol.48 , pp. 232-242
    • Punathil, T.1    Katiyar, S.K.2
  • 30
    • 0023019285 scopus 로고
    • Severe depletion in liver glutathione during physical exercise
    • Pyke S, Lew H, and Quintanilha A. Severe depletion in liver glutathione during physical exercise. Biochem Biophys Res Commun 139: 926-931, 1986.
    • (1986) Biochem Biophys Res Commun , vol.139 , pp. 926-931
    • Pyke, S.1    Lew, H.2    Quintanilha, A.3
  • 32
    • 51249104026 scopus 로고    scopus 로고
    • Pro-oxidant shift in glutathione redox state during aging
    • Rebrin I and Sohal RS. Pro-oxidant shift in glutathione redox state during aging. Adv Drug Deliv Rev 60: 1545-1552, 2008.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1545-1552
    • Rebrin, I.1    Sohal, R.S.2
  • 33
    • 37349110355 scopus 로고    scopus 로고
    • Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways
    • Rodgers JT, Lerin C, Gerhart-Hines Z, and Puigserver P. Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. FEBS Lett 582: 46-53, 2008.
    • (2008) FEBS Lett , vol.582 , pp. 46-53
    • Rodgers, J.T.1    Lerin, C.2    Gerhart-Hines, Z.3    Puigserver, P.4
  • 34
    • 14544282413 scopus 로고    scopus 로고
    • Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
    • Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, and Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434: 113-118, 2005.
    • (2005) Nature , vol.434 , pp. 113-118
    • Rodgers, J.T.1    Lerin, C.2    Haas, W.3    Gygi, S.P.4    Spiegelman, B.M.5    Puigserver, P.6
  • 35
    • 79953232671 scopus 로고    scopus 로고
    • Exercise increases mitochondrial PGC-1{alpha} content and promotes nuclear-mitochondrial crosstalk to coordinate mitochondrial biogenesis
    • Safdar A, Little JP, Stokl AJ, Hettinga BP, Akhtar M, and Tarnopolsky MA. Exercise increases mitochondrial PGC-1{alpha} content and promotes nuclear-mitochondrial crosstalk to coordinate mitochondrial biogenesis. J Biol Chem 286: 10605-17, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 10605-10617
    • Safdar, A.1    Little, J.P.2    Stokl, A.J.3    Hettinga, B.P.4    Akhtar, M.5    Tarnopolsky, M.A.6
  • 37
    • 0026443497 scopus 로고
    • Exhaustive physical exercise causes oxidation of glutathione status in blood: Prevention by an-tioxidant administration
    • Sastre J, Asensi M, Gasco E, Pallardo FV, Ferrero JA, Fur-ukawa T, and Vina J. Exhaustive physical exercise causes oxidation of glutathione status in blood: prevention by an-tioxidant administration. Am J Physiol 263: R992-R995, 1992.
    • (1992) Am J Physiol , vol.263
    • Sastre, J.1    Asensi, M.2    Gasco, E.3    Pallardo, F.V.4    Ferrero, J.A.5    Fur-Ukawa, T.6    Vina, J.7
  • 38
    • 42049114034 scopus 로고    scopus 로고
    • Transcriptional paradigms in mammalian mitochondrial biogenesis and function
    • Scarpulla RC. Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol Rev 88: 611-638, 2008.
    • (2008) Physiol Rev , vol.88 , pp. 611-638
    • Scarpulla, R.C.1
  • 39
    • 81355153987 scopus 로고    scopus 로고
    • PGC-1alpha, a key modulator of p53, promotes cell survival upon metabolic stress
    • Sen N, Satija YK, and Das S. PGC-1alpha, a key modulator of p53, promotes cell survival upon metabolic stress. Mol Cell 44: 621-634, 2011.
    • (2011) Mol Cell , vol.44 , pp. 621-634
    • Sen, N.1    Satija, Y.K.2    Das, S.3
  • 40
    • 42449132297 scopus 로고    scopus 로고
    • Transcriptional control of energy homeo-stasis through the PGC1 coactivators
    • discussion 6-12, 162-163, 196-203
    • Spiegelman BM. Transcriptional control of energy homeo-stasis through the PGC1 coactivators. Novartis Found Symp 286: 3-6; discussion 6-12, 162-163, 196-203, 2007.
    • (2007) Novartis Found Symp , vol.286 , pp. 3-6
    • Spiegelman, B.M.1
  • 42
    • 33644652602 scopus 로고    scopus 로고
    • Airing out an antioxidant role for the tumor suppressor p53
    • Tomko RJ, Jr., Bansal P, and Lazo JS. Airing out an antioxidant role for the tumor suppressor p53. Mol Interv 6: 23-25, 2006.
    • (2006) Mol Interv , vol.6 , pp. 23-25
    • Tomko, Jr.R.J.1    Bansal, P.2    Lazo, J.S.3
  • 43
    • 19444365211 scopus 로고    scopus 로고
    • PGC-1alpha regulates the mitochondrial antioxi-dant defense system in vascular endothelial cells
    • Valle I, Alvarez-Barrientos A, Arza E, Lamas S, and Mon-salve M. PGC-1alpha regulates the mitochondrial antioxi-dant defense system in vascular endothelial cells. Cardiovasc Res 66: 562-573, 2005.
    • (2005) Cardiovasc Res , vol.66 , pp. 562-573
    • Valle, I.1    Alvarez-Barrientos, A.2    Arza, E.3    Lamas, S.4    Mon-Salve, M.5
  • 44
    • 79955104610 scopus 로고    scopus 로고
    • Modulation of intracellular glutathione affects adipo-genesis in 3T3-L1 cells
    • Vigilanza P, Aquilano K, Baldelli S, Rotilio G, and Ciriolo MR. Modulation of intracellular glutathione affects adipo-genesis in 3T3-L1 cells. J Cell Physiol 226: 2016-2024, 2011.
    • (2011) J Cell Physiol , vol.226 , pp. 2016-2024
    • Vigilanza, P.1    Aquilano, K.2    Baldelli, S.3    Rotilio, G.4    Ciriolo, M.R.5
  • 45
    • 0027203402 scopus 로고
    • Fasting-induced Depletion of Glutathione in the Aging Mouse
    • Vogt BL and Richie JP, Jr. Fasting-induced depletion of glutathione in the aging mouse. Biochem Pharmacol 46: 257-263, 1993.
    • (1993) Biochem Pharmacol , vol.46 , pp. 257-263
    • Vogt, B.L.1    Richie, Jr.J.P.2
  • 46
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the light: The growing complexity of p53
    • Vousden KH and Prives C. Blinded by the light: the growing complexity of p53. Cell 137: 413-431, 2009.
    • (2009) Cell , vol.137 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 48
    • 1542376929 scopus 로고    scopus 로고
    • Glu-tathione metabolism and its implications for health
    • Wu G, Fang YZ, Yang S, Lupton JR, and Turner ND. Glu-tathione metabolism and its implications for health. J Nutr 134: 489-492, 2004.
    • (2004) J Nutr , vol.134 , pp. 489-492
    • Wu, G.1    Fang, Y.Z.2    Yang, S.3    Lupton, J.R.4    Turner, N.D.5


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