Inhibition of non-small cell lung cancer cell migration by grape seed proanthocyanidins is mediated through the inhibition of nitric oxide, guanylate cyclase, and ERK1/2

Molecular Carcinogenesis

Volumn 48, Issue 3, 2009, Pages 232-242

  Punathil, Thejass ^a   Katiyar, Santosh K ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

Grape seed proanthocyanidins; Guanylate cyclase; Lung cancer cells; Mitogen activated protein kinase; Nitric oxide; Tumor cell migration

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ARGININE; CYCLIC GMP; GRAPE SEED EXTRACT; GUANYLATE CYCLASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROANTHOCYANIDIN DERIVATIVE; UO 126; 1H (1,2,4)OXADIAZOLO(4,3 A)QUINOXALIN 1 ONE; 1H-(1,2,4)OXADIAZOLO(4,3-A)QUINOXALIN-1-ONE; 8 BROMO CYCLIC GMP; 8-BROMOCYCLIC GMP; CELL SURFACE RECEPTOR; DRUG DERIVATIVE; ENZYME INHIBITOR; GRAPE SEED PROANTHOCYANIDINS; GUANYLATE CYCLASE 1; OXADIAZOLE DERIVATIVE; PLANT EXTRACT; PROANTHOCYANIDIN; QUINOXALINE DERIVATIVE;

ARTICLE; CANCER CELL; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ADENOCARCINOMA; CELL MOTION; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; GRAPE; LARGE CELL CARCINOMA; LUNG TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL CULTURE; WESTERN BLOTTING;

VITACEAE;

ADENOCARCINOMA; BLOTTING, WESTERN; CARCINOMA, LARGE CELL; CARCINOMA, NON-SMALL-CELL LUNG; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CYCLIC GMP; ENZYME INHIBITORS; FLUORESCENT ANTIBODY TECHNIQUE; GUANYLATE CYCLASE; HUMANS; LUNG NEOPLASMS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXADIAZOLES; PLANT EXTRACTS; PROANTHOCYANIDINS; QUINOXALINES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; VITIS;

EID: 62349134367     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20473     Document Type: Article

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