-
1
-
-
0028847134
-
Molecular cloning of a novel widely expressed human 80 kDa 17 beta-hydroxysteroid dehydrogenase IV
-
Adamski J, Normand T, Leenders F, Monte D, Begue A, Stehelin D, Jungblut PW, de Launoit Y (1995) Molecular cloning of a novel widely expressed human 80 kDa 17 beta-hydroxysteroid dehydrogenase IV. Biochem J 311 (Pt 2):437-443
-
(1995)
Biochem J
, vol.311
, Issue.PART 2
, pp. 437-443
-
-
Adamski, J.1
Normand, T.2
Leenders, F.3
Monte, D.4
Begue, A.5
Stehelin, D.6
Jungblut, P.W.7
De Launoit, Y.8
-
2
-
-
45849133110
-
Endogenous sex hormones and endometrial cancer risk in women in the European Prospective Investigation into Cancer and Nutrition (EPIC
-
Allen NE, Key TJ, Dossus L, Rinaldi S, Cust A, Lukanova A, Peeters PH, Onland-Moret NC, Lahmann PH, Berrino F, Panico S, Larranaga N, Pera G, Tormo MJ, Sanchez MJ, Ramon Quiros J, Ardanaz E, Tjonneland A, Olsen A, Chang-Claude J, Linseisen J, Schulz M, Boeing H, Lundin E, Palli D, Overvad K, Clavel-Chapelon F, Boutron-Ruault MC, Bingham S, Khaw KT, Bueno-de-Mesquita HB, Trichopoulou A, Trichopoulos D, Naska A, Tumino R, Riboli E, Kaaks R (2008) Endogenous sex hormones and endometrial cancer risk in women in the European Prospective Investigation into Cancer and Nutrition (EPIC). Endocr Relat Cancer 15:485-497
-
(2008)
Endocr Relat Cancer
, vol.15
, pp. 485-497
-
-
Allen, N.E.1
Key, T.J.2
Dossus, L.3
Rinaldi, S.4
Cust, A.5
Lukanova, A.6
Peeters, P.H.7
Onland-Moret, N.C.8
Lahmann, P.H.9
Berrino, F.10
Panico, S.11
Larranaga, N.12
Pera, G.13
Tormo, M.J.14
Sanchez, M.J.15
Ramon Quiros, J.16
Ardanaz, E.17
Tjonneland, A.18
Olsen, A.19
Chang-Claude, J.20
Linseisen, J.21
Schulz, M.22
Boeing, H.23
Lundin, E.24
Palli, D.25
Overvad, K.26
Clavel-Chapelon, F.27
Boutron-Ruault, M.C.28
Bingham, S.29
Khaw, K.T.30
Bueno-De-Mesquita, H.B.31
Trichopoulou, A.32
Trichopoulos, D.33
Naska, A.34
Tumino, R.35
Riboli, E.36
Kaaks, R.37
more..
-
3
-
-
0029864222
-
Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice
-
Arbeit JM, Howley PM, Hanahan D (1996) Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice. Proc Natl Acad Sci U S A 93:2930-2935
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 2930-2935
-
-
Arbeit, J.M.1
Howley, P.M.2
Hanahan, D.3
-
4
-
-
0024399420
-
Preparation of 14, 15-secoestra-1, 35(10)-trien-15-ynes inhibitors of estradiol dehydrogenase
-
Auchus RJ, Palmer JO, Carrell HL, Covey DF (1989) Preparation of 14,15-secoestra-1,3,5(10)-trien-15-ynes, inhibitors of estradiol dehydrogenase. Steroids 53:77-96
-
(1989)
Steroids
, vol.53
, pp. 77-96
-
-
Auchus, R.J.1
Palmer, J.O.2
Carrell, H.L.3
Covey, D.F.4
-
5
-
-
0031565966
-
Steroid receptor phylogeny and vertebrate origins
-
Baker ME (1997) Steroid receptor phylogeny and vertebrate origins. Mol Cell Endocrinol 135:101-107
-
(1997)
Mol Cell Endocrinol
, vol.135
, pp. 101-107
-
-
Baker, M.E.1
-
6
-
-
0035931125
-
Evolution of 17beta-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action
-
Baker ME (2001) Evolution of 17beta-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action. Mol Cell Endocrinol 171:211-215
-
(2001)
Mol Cell Endocrinol
, vol.171
, pp. 211-215
-
-
Baker, M.E.1
-
7
-
-
31444440675
-
Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alphadihydrotestosterone: A potential therapeutic target for androgen-dependent disease
-
Bauman DR, Steckelbroeck S, Williams MV, Peehl DM, Penning TM (2006) Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alphadihydrotestosterone: A potential therapeutic target for androgen-dependent disease. Mol Endocrinol 20:444-458
-
(2006)
Mol Endocrinol
, vol.20
, pp. 444-458
-
-
Bauman, D.R.1
Steckelbroeck, S.2
Williams, M.V.3
Peehl, D.M.4
Penning, T.M.5
-
8
-
-
34249800682
-
Role of microsomal retinol/sterol dehydrogenase-like shortchain dehydrogenases/reductases in the oxidation and epimerization of 3alpha-hydroxysteroids in human tissues
-
Belyaeva OV, Chetyrkin SV, Clark AL, Kostereva NV, SantaCruz KS, Chronwall BM, Kedishvili NY (2007) Role of microsomal retinol/sterol dehydrogenase-like shortchain dehydrogenases/reductases in the oxidation and epimerization of 3alpha-hydroxysteroids in human tissues. Endocrinology 148:2148-2156
-
(2007)
Endocrinology
, vol.148
, pp. 2148-2156
-
-
Belyaeva, O.V.1
Chetyrkin, S.V.2
Clark, A.L.3
Kostereva, N.V.4
SantaCruz, K.S.5
Chronwall, B.M.6
Kedishvili, N.Y.7
-
9
-
-
72249090207
-
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone
-
Bellavance E, Luu-The V, Poirier D (2009) Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. J Med Chem 52:7488-7502
-
(2009)
J Med Chem
, vol.52
, pp. 7488-7502
-
-
Bellavance, E.1
Luu-The, V.2
Poirier, D.3
-
10
-
-
39749180158
-
Ovarian cancer and oral contraceptives: Collaborative reanalysis of data from 45 epidemiological studies including 23,257 women with ovarian cancer and 87,303 controls
-
Beral V, Doll R, Hermon C, Peto R, Reeves G (2008) Ovarian cancer and oral contraceptives: Collaborative reanalysis of data from 45 epidemiological studies including 23,257 women with ovarian cancer and 87,303 controls. Lancet 371:303-314
-
(2008)
Lancet
, vol.371
, pp. 303-314
-
-
Beral, V.1
Doll, R.2
Hermon, C.3
Peto, R.4
Reeves, G.5
-
11
-
-
67449085159
-
Single and multigenic analysis of the association between variants in 12 steroid hormone metabolism genes and risk of prostate cancer
-
Beuten J, Gelfond JA, Franke JL, Weldon KS, Crandall AC, Johnson-Pais TL, Thompson IM, Leach RJ (2009) Single and multigenic analysis of the association between variants in 12 steroid hormone metabolism genes and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev 18:1869-1880
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 1869-1880
-
-
Beuten, J.1
Gelfond, J.A.2
Franke, J.L.3
Weldon, K.S.4
Crandall, A.C.5
Johnson-Pais, T.L.6
Thompson, I.M.7
Leach, R.J.8
-
12
-
-
0036668766
-
Androgenic and estrogenic 17beta-hydroxysteroid dehydrogenase/ 17-ketosteroid reductase in human ovarian epithelial tumors: Evidence for the type 1, 2 and 5 isoforms
-
Blomquist CH, Bonenfant M, McGinley DM, Posalaky Z, Lakatua DJ, Tuli-Puri S, Bealka DG, Tremblay Y (2002) Androgenic and estrogenic 17beta-hydroxysteroid dehydrogenase/ 17-ketosteroid reductase in human ovarian epithelial tumors: Evidence for the type 1, 2 and 5 isoforms. J Steroid Biochem Mol Biol 81:343-351
-
(2002)
J Steroid Biochem Mol Biol
, vol.81
, pp. 343-351
-
-
Blomquist, C.H.1
Bonenfant, M.2
McGinley, D.M.3
Posalaky, Z.4
Lakatua, D.J.5
Tuli-Puri, S.6
Bealka, D.G.7
Tremblay, Y.8
-
13
-
-
0020660717
-
Two pathogenetic types of endometrial carcinoma
-
Bokhman JV (1983) Two pathogenetic types of endometrial carcinoma. Gynecol Oncol 15:10-17
-
(1983)
Gynecol Oncol
, vol.15
, pp. 10-17
-
-
Bokhman, J.V.1
-
14
-
-
0004629130
-
Estrogen receptor alpha (ER-alpha) and beta (ER-beta) mRNAs in normal ovary, ovarian serous cystadenocarcinoma and ovarian cancer cell lines: Down-regulation of ER-beta in neoplastic tissues
-
Brandenberger AW, Tee MK, Jaffe RB (1998) Estrogen receptor alpha (ER-alpha) and beta (ER-beta) mRNAs in normal ovary, ovarian serous cystadenocarcinoma and ovarian cancer cell lines: Down-regulation of ER-beta in neoplastic tissues. J Clin Endocrinol Metab 83:1025-1028
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 1025-1028
-
-
Brandenberger, A.W.1
Tee, M.K.2
Jaffe, R.B.3
-
15
-
-
0035931119
-
Pan1b (17betaHSD11)-enzymatic activity and distribution in the lung
-
Brereton P, Suzuki T, Sasano H, Li K, Duarte C, Obeyesekere V, Haeseleer F, Palczewski K, Smith I, Komesaroff P, Krozowski Z (2001) Pan1b (17betaHSD11)-enzymatic activity and distribution in the lung. Mol Cell Endocrinol 171:111-117
-
(2001)
Mol Cell Endocrinol
, vol.171
, pp. 111-117
-
-
Brereton, P.1
Suzuki, T.2
Sasano, H.3
Li, K.4
Duarte, C.5
Obeyesekere, V.6
Haeseleer, F.7
Palczewski, K.8
Smith, I.9
Komesaroff, P.10
Krozowski, Z.11
-
16
-
-
79957722662
-
Inhibitors of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3): Overview and structural insights
-
Byrns MC, Jin Y, Penning TM (2010) Inhibitors of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3): Overview and structural insights. J Steroid Biochem Mol Biol 125:95-104
-
(2010)
J Steroid Biochem Mol Biol
, vol.125
, pp. 95-104
-
-
Byrns, M.C.1
Jin, Y.2
Penning, T.M.3
-
17
-
-
0031767279
-
Expression of types 1,2, and 3 17 beta-hydroxysteroid dehydrogenase in subcutaneous abdominal and intra-abdominal adipose tissue of women
-
Corbould AM, Judd SJ, Rodgers RJ (1998) Expression of types 1, 2, and 3 17 beta-hydroxysteroid dehydrogenase in subcutaneous abdominal and intra-abdominal adipose tissue of women. J Clin Endocrinol Metab 83:187-194
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 187-194
-
-
Corbould, A.M.1
Judd, S.J.2
Rodgers, R.J.3
-
18
-
-
0038070588
-
17 beta-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells
-
Chai Z, Brereton P, Suzuki T, Sasano H, Obeyesekere V, Escher G, Saffery R, Fuller P, Enriquez C, Krozowski Z (2003) 17 beta-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells. Endocrinology 144:2084-2091
-
(2003)
Endocrinology
, vol.144
, pp. 2084-2091
-
-
Chai, Z.1
Brereton, P.2
Suzuki, T.3
Sasano, H.4
Obeyesekere, V.5
Escher, G.6
Saffery, R.7
Fuller, P.8
Enriquez, C.9
Krozowski, Z.10
-
19
-
-
77951900245
-
Genomic analyses of hormone signaling and gene regulation
-
Cheung E, Kraus WL (2010) Genomic analyses of hormone signaling and gene regulation. Annu Rev Physiol 72:191-218
-
(2010)
Annu Rev Physiol
, vol.72
, pp. 191-218
-
-
Cheung, E.1
Kraus, W.L.2
-
20
-
-
79961108678
-
Metabolic alteration of urinary steroids in pre-and postmenopausal women, and men with papillary thyroid carcinoma
-
Choi MH, Moon JY, Cho SH, Chung BC, Lee EJ (2011) Metabolic alteration of urinary steroids in pre-and postmenopausal women, and men with papillary thyroid carcinoma. BMC Cancer 11:342
-
(2011)
BMC Cancer
, vol.11
, pp. 342
-
-
Choi, M.H.1
Moon, J.Y.2
Cho, S.H.3
Chung, B.C.4
Lee, E.J.5
-
22
-
-
60249091167
-
Steroidconverting enzymes in human ovarian carcinomas
-
Chura JC, Ryu HS, Simard M, Poirier D, Tremblay Y, Brooker DC, Blomquist CH, Argenta PA (2009) Steroidconverting enzymes in human ovarian carcinomas. Mol Cell Endocrinol 301:51-58
-
(2009)
Mol Cell Endocrinol
, vol.301
, pp. 51-58
-
-
Chura, J.C.1
Ryu, H.S.2
Simard, M.3
Poirier, D.4
Tremblay, Y.5
Brooker, D.C.6
Blomquist, C.H.7
Argenta, P.A.8
-
23
-
-
33847074176
-
Interaction of soy and 17beta-HSD1 gene polymorphisms in the risk of endometrial cancer
-
Dai Q, Xu WH, Long JR, Courtney R, Xiang YB, Cai Q, Cheng J, Zheng W, Shu XO (2007) Interaction of soy and 17beta-HSD1 gene polymorphisms in the risk of endometrial cancer. Pharmacogenet Genomics 17:161-167
-
(2007)
Pharmacogenet Genomics
, vol.17
, pp. 161-167
-
-
Dai, Q.1
Xu, W.H.2
Long, J.R.3
Courtney, R.4
Xiang, Y.B.5
Cai, Q.6
Cheng, J.7
Zheng, W.8
Shu, X.O.9
-
24
-
-
0019160416
-
17 betahydroxysteroid dehydrogenase deficiency in malignant interstitial cell carcinoma of the testis
-
Davis S, DiMartino NA, Schneider G (1980) 17 betahydroxysteroid dehydrogenase deficiency in malignant interstitial cell carcinoma of the testis. J Clin Endocrinol Metab 51:1293-1297
-
(1980)
J Clin Endocrinol Metab
, vol.51
, pp. 1293-1297
-
-
Davis, S.1
DiMartino, N.A.2
Schneider, G.3
-
25
-
-
40749094550
-
17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer
-
Day JM, Foster PA, Tutill HJ, Parsons MF, Newman SP, Chander SK, Allan GM, Lawrence HR, Vicker N, Potter BV, Reed MJ, Purohit A (2008) 17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer. Int J Cancer 122:1931-1940
-
(2008)
Int J Cancer
, vol.122
, pp. 1931-1940
-
-
Day, J.M.1
Foster, P.A.2
Tutill, H.J.3
Parsons, M.F.4
Newman, S.P.5
Chander, S.K.6
Allan, G.M.7
Lawrence, H.R.8
Vicker, N.9
Potter, B.V.10
Reed, M.J.11
Purohit, A.12
-
26
-
-
60249088055
-
Development of hormone-dependent prostate cancer models for the evaluation of inhibitors of 17betahydroxysteroid dehydrogenase type 3
-
Day JM, Tutill HJ, Foster PA, Bailey HV, Heaton WB, Sharland CM, Vicker N, Potter BV, Purohit A, Reed MJ (2009) Development of hormone-dependent prostate cancer models for the evaluation of inhibitors of 17betahydroxysteroid dehydrogenase type 3. Mol Cell Endocrinol 301:251-258
-
(2009)
Mol Cell Endocrinol
, vol.301
, pp. 251-258
-
-
Day, J.M.1
Tutill, H.J.2
Foster, P.A.3
Bailey, H.V.4
Heaton, W.B.5
Sharland, C.M.6
Vicker, N.7
Potter, B.V.8
Purohit, A.9
Reed, M.J.10
-
28
-
-
53849119147
-
Design and validation of specific inhibitors of 17beta-hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis
-
Day JM, Tutill HJ, Purohit A, Reed MJ (2008) Design and validation of specific inhibitors of 17beta-hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis. Endocr Relat Cancer 15:665-692
-
(2008)
Endocr Relat Cancer
, vol.15
, pp. 665-692
-
-
Day, J.M.1
Tutill, H.J.2
Purohit, A.3
Reed, M.J.4
-
29
-
-
0032176301
-
17Beta-hydroxysteroid dehydrogenases in human bone cells
-
Dong Y, Qiu QQ, Debear J, Lathrop WF, Bertolini DR, Tamburini PP (1998) 17Beta-hydroxysteroid dehydrogenases in human bone cells. J Bone Miner Res 13:1539-1546
-
(1998)
J Bone Miner Res
, vol.13
, pp. 1539-1546
-
-
Dong, Y.1
Qiu, Q.Q.2
Debear, J.3
Lathrop, W.F.4
Bertolini, D.R.5
Tamburini, P.P.6
-
30
-
-
78549283832
-
Polymorphisms in genes involved in the estrogen pathway and mammographic density
-
Dumas I, Diorio C (2010) Polymorphisms in genes involved in the estrogen pathway and mammographic density. BMC Cancer 10:636
-
(2010)
BMC Cancer
, vol.10
, pp. 636
-
-
Dumas, I.1
Diorio, C.2
-
31
-
-
0035931120
-
Distribution of 17beta-hydroxysteroid dehydrogenases in human osteoblast-like cells
-
Feix M, Wolf L, Schweikert HU (2001) Distribution of 17beta- hydroxysteroid dehydrogenases in human osteoblast-like cells. Mol Cell Endocrinol 171:163-164
-
(2001)
Mol Cell Endocrinol
, vol.171
, pp. 163-164
-
-
Feix, M.1
Wolf, L.2
Schweikert, H.U.3
-
32
-
-
77449149129
-
Association of testicular germ cell tumor with polymorphisms in estrogen receptor and steroid metabolism genes
-
Ferlin A, Ganz F, Pengo M, Selice R, Frigo AC, Foresta C (2010) Association of testicular germ cell tumor with polymorphisms in estrogen receptor and steroid metabolism genes. Endocr Relat Cancer 17:17-25
-
(2010)
Endocr Relat Cancer
, vol.17
, pp. 17-25
-
-
Ferlin, A.1
Ganz, F.2
Pengo, M.3
Selice, R.4
Frigo, A.C.5
Foresta, C.6
-
33
-
-
52549133326
-
Genetic variation in hormone metabolizing genes and risk of testicular germ cell tumors
-
Figueroa JD, Sakoda LC, Graubard BI, Chanock S, Rubertone MV, Erickson RL, McGlynn KA (2008) Genetic variation in hormone metabolizing genes and risk of testicular germ cell tumors. Cancer Causes Control 19:917-929
-
(2008)
Cancer Causes Control
, vol.19
, pp. 917-929
-
-
Figueroa, J.D.1
Sakoda, L.C.2
Graubard, B.I.3
Chanock, S.4
Rubertone, M.V.5
Erickson, R.L.6
McGlynn, K.A.7
-
34
-
-
54049116349
-
Design and synthesis of bisubstrate inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: Overview and perspectives
-
Fournier D, Poirier D, Mazumdar M, Lin SX (2008) Design and synthesis of bisubstrate inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: Overview and perspectives. Eur J Med Chem 43:2298-2306
-
(2008)
Eur J Med Chem
, vol.43
, pp. 2298-2306
-
-
Fournier, D.1
Poirier, D.2
Mazumdar, M.3
Lin, S.X.4
-
35
-
-
60249090902
-
Estrogen formation in endometrial and cervix cancer cell lines: Involvement of aromatase, steroid sulfatase and 17beta-hydroxysteroid dehydrogenases (types 1, 57 and 12
-
Fournier MA, Poirier D (2009) Estrogen formation in endometrial and cervix cancer cell lines: Involvement of aromatase, steroid sulfatase and 17beta-hydroxysteroid dehydrogenases (types 1, 5, 7 and 12). Mol Cell Endocrinol 301:142-145
-
(2009)
Mol Cell Endocrinol
, vol.301
, pp. 142-145
-
-
Fournier, M.A.1
Poirier, D.2
-
36
-
-
0023743171
-
Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated
-
Funder JW, Pearce PT, Smith R, Smith AI (1988) Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated. Science 242:583-585
-
(1988)
Science
, vol.242
, pp. 583-585
-
-
Funder, J.W.1
Pearce, P.T.2
Smith, R.3
Smith, A.I.4
-
37
-
-
33645987281
-
Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17betahydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma
-
Fung KM, Samara EN, Wong C, Metwalli A, Krlin R, Bane B, Liu CZ, Yang JT, Pitha JV, Culkin DJ, Kropp BP, Penning TM, Lin HK (2006) Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17betahydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma. Endocr Relat Cancer 13:169-180
-
(2006)
Endocr Relat Cancer
, vol.13
, pp. 169-180
-
-
Fung, K.M.1
Samara, E.N.2
Wong, C.3
Metwalli, A.4
Krlin, R.5
Bane, B.6
Liu, C.Z.7
Yang, J.T.8
Pitha, J.V.9
Culkin, D.J.10
Kropp, B.P.11
Penning, T.M.12
Lin, H.K.13
-
38
-
-
0028023426
-
Expression of 17 beta-hydroxysteroid dehydrogenase in human granulosa cells: Correlation with follicular size, cytochrome P450 aromatase activity and oestradiol production
-
Ghersevich SA, Poutanen MH, Martikainen HK, Vihko RK (1994) Expression of 17 beta-hydroxysteroid dehydrogenase in human granulosa cells: Correlation with follicular size, cytochrome P450 aromatase activity and oestradiol production. J Endocrinol 143:139-150
-
(1994)
J Endocrinol
, vol.143
, pp. 139-150
-
-
Ghersevich, S.A.1
Poutanen, M.H.2
Martikainen, H.K.3
Vihko, R.K.4
-
39
-
-
0027442570
-
Evidence for increasing incidence of abnormalities of the human testis: A review
-
Giwercman A, Carlsen E, Keiding N, Skakkebaek NE (1993) Evidence for increasing incidence of abnormalities of the human testis: A review. Environ Health Perspect 101 (Suppl 2):65-71
-
(1993)
Environ Health Perspect
, vol.101
, Issue.SUPPL. 2
, pp. 65-71
-
-
Giwercman, A.1
Carlsen, E.2
Keiding, N.3
Skakkebaek, N.E.4
-
40
-
-
0037427071
-
Amplification of HSD17B1 and ERBB2 in primary breast cancer
-
Gunnarsson C, Ahnstrom M, Kirschner K, Olsson B, Nordenskjold B, Rutqvist LE, Skoog L, Stal O (2003) Amplification of HSD17B1 and ERBB2 in primary breast cancer. Oncogene 22:34-40
-
(2003)
Oncogene
, vol.22
, pp. 34-40
-
-
Gunnarsson, C.1
Ahnstrom, M.2
Kirschner, K.3
Olsson, B.4
Nordenskjold, B.5
Rutqvist, L.E.6
Skoog, L.7
Stal, O.8
-
41
-
-
15244352525
-
17beta-Hydroxysteroid dehydrogenases involved in local oestrogen synthesis have prognostic significance in breast cancer
-
Gunnarsson C, Hellqvist E, Stal O (2005) 17beta-Hydroxysteroid dehydrogenases involved in local oestrogen synthesis have prognostic significance in breast cancer. Br J Cancer 92:547-552
-
(2005)
Br J Cancer
, vol.92
, pp. 547-552
-
-
Gunnarsson, C.1
Hellqvist, E.2
Stal, O.3
-
42
-
-
0035529054
-
Abnormal expression of 17beta-hydroxysteroid dehydrogenases in breast cancer predicts late recurrence
-
Gunnarsson C, Olsson BM, Stal O (2001) Abnormal expression of 17beta-hydroxysteroid dehydrogenases in breast cancer predicts late recurrence. Cancer Res 61:8448-8451
-
(2001)
Cancer Res
, vol.61
, pp. 8448-8451
-
-
Gunnarsson, C.1
Olsson, B.M.2
Stal, O.3
-
43
-
-
72049089820
-
Coumarins as novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for potential treatment of prostate cancer
-
Harada K, Kubo H, Tomigahara Y, Nishioka K, Takahashi J, Momose M, Inoue S, Kojima A (2010) Coumarins as novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for potential treatment of prostate cancer. Bioorg Med Chem Lett 20:272-275
-
(2010)
Bioorg Med Chem Lett
, vol.20
, pp. 272-275
-
-
Harada, K.1
Kubo, H.2
Tomigahara, Y.3
Nishioka, K.4
Takahashi, J.5
Momose, M.6
Inoue, S.7
Kojima, A.8
-
44
-
-
77949752567
-
Intratumoral estrogen disposition in breast cancer
-
Haynes BP, Straume AH, Geisler J, A'Hern R, Helle H, Smith IE, Lonning PE, Dowsett M (2010) Intratumoral estrogen disposition in breast cancer. Clin Cancer Res 16:1790-1801
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1790-1801
-
-
Haynes, B.P.1
Straume, A.H.2
Geisler, J.3
A'Hern, R.4
Helle, H.5
Smith, I.E.6
Lonning, P.E.7
Dowsett, M.8
-
46
-
-
76249096762
-
Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer
-
Hofland J, van Weerden WM, Dits NF, Steenbergen J, van Leenders GJ, Jenster G, Schroder FH, de Jong FH (2010) Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer. Cancer Res 70:1256-1264
-
(2010)
Cancer Res
, vol.70
, pp. 1256-1264
-
-
Hofland, J.1
Van Weerden, W.M.2
Dits, N.F.3
Steenbergen, J.4
Van Leenders, G.J.5
Jenster, G.6
Schroder, F.H.7
De Jong, F.H.8
-
47
-
-
0016516520
-
In vivo uptake and metabolism of 3-h-5alpha-androstane-3alpha,17beta-diol and of 3-h-5alpha-androstane-3beta, 17beta-diol by human prostatic hypertrophy
-
Horst HJ, Dennis M, Kaufmann J, Voigt KD (1975) In vivo uptake and metabolism of 3-h-5alpha-androstane-3alpha,17beta-diol and of 3-h-5alpha-androstane-3beta, 17beta-diol by human prostatic hypertrophy. Acta Endocrinol (Copenh) 79:394-402
-
(1975)
Acta Endocrinol (Copenh
, vol.79
, pp. 394-402
-
-
Horst, H.J.1
Dennis, M.2
Kaufmann, J.3
Voigt, K.D.4
-
48
-
-
0034703043
-
Molecular characterization of a first human 3(alpha->beta)- hydroxysteroid epimerase
-
Huang XF, Luu-The V (2000) Molecular characterization of a first human 3(alpha->beta)-hydroxysteroid epimerase. J Biol Chem 275:29452-29457
-
(2000)
J Biol Chem
, vol.275
, pp. 29452-29457
-
-
Huang, X.F.1
Luu-The, V.2
-
49
-
-
33644900197
-
Evaluation of inhibitors for 17betahydroxysteroid dehydrogenase type 1 in vivo in immunodeficient mice inoculated with MCF-7 cells stably expressing the recombinant human enzyme
-
Husen B, Huhtinen K, Poutanen M, Kangas L, Messinger J, Thole H (2006) Evaluation of inhibitors for 17betahydroxysteroid dehydrogenase type 1 in vivo in immunodeficient mice inoculated with MCF-7 cells stably expressing the recombinant human enzyme. Mol Cell Endocrinol 248:109-113
-
(2006)
Mol Cell Endocrinol
, vol.248
, pp. 109-113
-
-
Husen, B.1
Huhtinen, K.2
Poutanen, M.3
Kangas, L.4
Messinger, J.5
Thole, H.6
-
50
-
-
33751240474
-
Human hydroxysteroid (17-beta) dehydrogenase 1 expression enhances estrogen sensitivity of MCF-7 breast cancer cell xenografts
-
Husen B, Huhtinen K, Saloniemi T, Messinger J, Thole HH, Poutanen M (2006) Human hydroxysteroid (17-beta) dehydrogenase 1 expression enhances estrogen sensitivity of MCF-7 breast cancer cell xenografts. Endocrinology 147:5333-5339
-
(2006)
Endocrinology
, vol.147
, pp. 5333-5339
-
-
Husen, B.1
Huhtinen, K.2
Saloniemi, T.3
Messinger, J.4
Thole, H.H.5
Poutanen, M.6
-
51
-
-
0018141747
-
Studies on the mechanism of 3 alpha-androstanediol-induced growth of the dog prostate
-
Jacobi GH, Moore RJ, Wilson JD (1978) Studies on the mechanism of 3 alpha-androstanediol-induced growth of the dog prostate. Endocrinology 102:1748-1758
-
(1978)
Endocrinology
, vol.102
, pp. 1748-1758
-
-
Jacobi, G.H.1
Moore, R.J.2
Wilson, J.D.3
-
52
-
-
33845728020
-
17beta-hydroxysteroid dehydrogenase 14 affects estradiol levels in breast cancer cells and is a prognostic marker in estrogen receptor-positive breast cancer
-
Jansson AK, Gunnarsson C, Cohen M, Sivik T, Stal O (2006) 17beta-hydroxysteroid dehydrogenase 14 affects estradiol levels in breast cancer cells and is a prognostic marker in estrogen receptor-positive breast cancer. Cancer Res 66:11471-11477
-
(2006)
Cancer Res
, vol.66
, pp. 11471-11477
-
-
Jansson, A.K.1
Gunnarsson, C.2
Cohen, M.3
Sivik, T.4
Stal, O.5
-
53
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61:69-90
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
54
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E (2010) Cancer statistics, 2010. CA Cancer J Clin 60:277-300
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
55
-
-
77950240539
-
Hydroxysteroid (17beta) dehydrogenase 7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos
-
Jokela H, Rantakari P, Lamminen T, Strauss L, Ola R, Mutka AL, Gylling H, Miettinen T, Pakarinen P, Sainio K, Poutanen M (2010) Hydroxysteroid (17beta) dehydrogenase 7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos. Endocrinology 151:1884-1892
-
(2010)
Endocrinology
, vol.151
, pp. 1884-1892
-
-
Jokela, H.1
Rantakari, P.2
Lamminen, T.3
Strauss, L.4
Ola, R.5
Mutka, A.L.6
Gylling, H.7
Miettinen, T.8
Pakarinen, P.9
Sainio, K.10
Poutanen, M.11
-
56
-
-
0015953531
-
An epidemiologic study of the relationship of reproductive experience to cancer of the ovary
-
Joly DJ, Lilienfeld AM, Diamond EL, Bross ID (1974) An epidemiologic study of the relationship of reproductive experience to cancer of the ovary. Am J Epidemiol 99:190-209
-
(1974)
Am J Epidemiol
, vol.99
, pp. 190-209
-
-
Joly, D.J.1
Lilienfeld, A.M.2
Diamond, E.L.3
Bross, I.D.4
-
57
-
-
0038823620
-
Estrogen receptors (alpha and beta) and 17beta-hydroxysteroid dehydrogenase type 1 and 2 in thyroid disorders: Possible in situ estrogen synthesis and actions
-
KawabataW, Suzuki T, Moriya T, Fujimori K, Naganuma H, Inoue S, Kinouchi Y, Kameyama K, Takami H, Shimosegawa T, Sasano H (2003) Estrogen receptors (alpha and beta) and 17beta-hydroxysteroid dehydrogenase type 1 and 2 in thyroid disorders: Possible in situ estrogen synthesis and actions.Mod Pathol 16:437-444
-
(2003)
Mod Pathol
, vol.16
, pp. 437-444
-
-
KawabataW Suzuki, T.1
Moriya, T.2
Fujimori, K.3
Naganuma, H.4
Inoue, S.5
Kinouchi, Y.6
Kameyama, K.7
Takami, H.8
Shimosegawa, T.9
Sasano, H.10
-
58
-
-
0036771843
-
Differential expression of 17beta-hydroxysteroid dehydrogenase isozyme genes in prostate cancer and noncancer tissues
-
Koh E, Noda T, Kanaya J, Namiki M (2002) Differential expression of 17beta-hydroxysteroid dehydrogenase isozyme genes in prostate cancer and noncancer tissues. Prostate 53:154-159
-
(2002)
Prostate
, vol.53
, pp. 154-159
-
-
Koh, E.1
Noda, T.2
Kanaya, J.3
Namiki, M.4
-
59
-
-
55449108364
-
Genetic variation in the HSD17B1 gene and risk of prostate cancer
-
Kraft P, Pharoah P, Chanock SJ, Albanes D, Kolonel LN, Hayes RB, Altshuler D, Andriole G, Berg C, Boeing H, Burtt NP, Bueno-de-Mesquita B, Calle EE, Cann H, Canzian F, ChenYC, Crawford DE,DunningAM, Feigelson HS, Freedman ML, Gaziano JM, Giovannucci E, Gonzalez CA, Haiman CA, Hallmans G, Henderson BE, Hirschhorn JN, Hunter DJ, Kaaks R, Key T, Le Marchand L, Ma J, Overvad K, Palli D, Pike MC, Riboli E, Rodriguez C, Setiawan WV, Stampfer MJ, Stram DO, Thomas G, Thun MJ, Travis R, Trichopoulou A, Virtamo J, Wacholder S (2005) Genetic variation in the HSD17B1 gene and risk of prostate cancer. PLoS Genet 1:e68
-
(2005)
PLoS Genet
, vol.1
-
-
Kraft, P.1
Pharoah, P.2
Chanock, S.J.3
Albanes, D.4
Kolonel, L.N.5
Hayes, R.B.6
Altshuler, D.7
Andriole, G.8
Berg, C.9
Boeing, H.10
Burtt, N.P.11
Bueno-de-Mesquita, B.12
Calle, E.E.13
Cann, H.14
Canzian, F.15
Chen, Y.C.16
Crawford, D.E.17
Dunning, A.M.18
Feigelson, H.S.19
Freedman, M.L.20
Gaziano, J.M.21
Giovannucci, E.22
Gonzalez, C.A.23
Haiman, C.A.24
Hallmans, G.25
Henderson, B.E.26
Hirschhorn, J.N.27
Hunter, D.J.28
Kaaks, R.29
Key, T.30
Le Marchand, L.31
Ma, J.32
Overvad, K.33
Palli, D.34
Pike, M.C.35
Riboli, E.36
Rodriguez, C.37
Setiawan, W.V.38
Stampfer, M.J.39
Stram, D.O.40
Thomas, G.41
Thun, M.J.42
Travis, R.43
Trichopoulou, A.44
Virtamo, J.45
Wacholder, S.46
more..
-
60
-
-
0032727093
-
Determination of cDNA, gene structure and chromosomal localization of the novel human 17betahydroxysteroid dehydrogenase type 7(1
-
Krazeisen A, Breitling R, Imai K, Fritz S, Moller G, Adamski J (1999) Determination of cDNA, gene structure and chromosomal localization of the novel human 17betahydroxysteroid dehydrogenase type 7(1). FEBS Lett 460:373-379
-
(1999)
FEBS Lett
, vol.460
, pp. 373-379
-
-
Krazeisen, A.1
Breitling, R.2
Imai, K.3
Fritz, S.4
Moller, G.5
Adamski, J.6
-
61
-
-
3142716735
-
Overview of the structural basis for transcription regulation by nuclear hormone receptors
-
Kumar R, Johnson BH, Thompson EB (2004) Overview of the structural basis for transcription regulation by nuclear hormone receptors. Essays Biochem 40:27-39
-
(2004)
Essays Biochem
, vol.40
, pp. 27-39
-
-
Kumar, R.1
Johnson, B.H.2
Thompson, E.B.3
-
62
-
-
0033054115
-
The structure of the nuclear hormone receptors
-
Kumar R, Thompson EB (1999) The structure of the nuclear hormone receptors. Steroids 64:310-319
-
(1999)
Steroids
, vol.64
, pp. 310-319
-
-
Kumar, R.1
Thompson, E.B.2
-
63
-
-
0031451570
-
Evolution of the nuclear receptor superfamily: Early diversification from an ancestral orphan receptor
-
Laudet V (1997) Evolution of the nuclear receptor superfamily: Early diversification from an ancestral orphan receptor. J Mol Endocrinol 19:207-226
-
(1997)
J Mol Endocrinol
, vol.19
, pp. 207-226
-
-
Laudet, V.1
-
64
-
-
77954506419
-
Circulating estrogens in endometrial cancer cases and their relationship with tissular expression of key estrogen biosynthesis and metabolic pathways
-
Lepine J, Audet-Walsh E, Gregoire J, Tetu B, Plante M, Menard V, Ayotte P, Brisson J, Caron P, Villeneuve L, Belanger A, Guillemette C (2010) Circulating estrogens in endometrial cancer cases and their relationship with tissular expression of key estrogen biosynthesis and metabolic pathways. J Clin Endocrinol Metab 95:2689-2698
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 2689-2698
-
-
Lepine, J.1
Audet-Walsh, E.2
Gregoire, J.3
Tetu, B.4
Plante, M.5
Menard, V.6
Ayotte, P.7
Brisson, J.8
Caron, P.9
Villeneuve, L.10
Belanger, A.11
Guillemette, C.12
-
65
-
-
0030784509
-
Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: Demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular distribution
-
Lin HK, Jez JM, Schlegel BP, Peehl DM, Pachter JA, Penning TM (1997) Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: Demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular distribution. Mol Endocrinol 11:1971-1984
-
(1997)
Mol Endocrinol
, vol.11
, pp. 1971-1984
-
-
Lin, H.K.1
Jez, J.M.2
Schlegel, B.P.3
Peehl, D.M.4
Pachter, J.A.5
Penning, T.M.6
-
66
-
-
9944264069
-
Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alphahydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate
-
Lin HK, Steckelbroeck S, Fung KM, Jones AN, Penning TM (2004) Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alphahydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate. Steroids 69:795-801
-
(2004)
Steroids
, vol.69
, pp. 795-801
-
-
Lin, H.K.1
Steckelbroeck, S.2
Fung, K.M.3
Jones, A.N.4
Penning, T.M.5
-
67
-
-
33947575594
-
Molecular cloning and expression analysis of a new gene for short-chain dehydrogenase/reductase 9
-
Liu S, Huang C, Li D, Ren W, Zhang H, Qi M, Li X, Yu L (2007) Molecular cloning and expression analysis of a new gene for short-chain dehydrogenase/reductase 9. Acta Biochim Pol 54:213-218
-
(2007)
Acta Biochim Pol
, vol.54
, pp. 213-218
-
-
Liu, S.1
Huang, C.2
Li, D.3
Ren, W.4
Zhang, H.5
Qi, M.6
Li, X.7
Yu, L.8
-
68
-
-
33644989471
-
Structure and function of human 17beta-hydroxysteroid dehydrogenases
-
Lukacik P, Kavanagh KL, Oppermann U (2006) Structure and function of human 17beta-hydroxysteroid dehydrogenases. Mol Cell Endocrinol 248:61-71
-
(2006)
Mol Cell Endocrinol
, vol.248
, pp. 61-71
-
-
Lukacik, P.1
Kavanagh, K.L.2
Oppermann, U.3
-
69
-
-
33947216707
-
Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity
-
Lukacik P, Keller B, Bunkoczi G, Kavanagh KL, Lee WH, Adamski J, Oppermann U (2007) Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. Biochem J 402:419-427
-
(2007)
Biochem J
, vol.402
, pp. 419-427
-
-
Lukacik, P.1
Keller, B.2
Bunkoczi, G.3
Kavanagh, K.L.4
Lee, W.H.5
Adamski, J.6
Oppermann, U.7
-
70
-
-
10744223927
-
Circulating levels of sex steroid hormones and risk of endometrial cancer in postmenopausal women
-
Lukanova A, Lundin E, Micheli A, Arslan A, Ferrari P, Rinaldi S, Krogh V, Lenner P, Shore RE, Biessy C, Muti P, Riboli E, Koenig KL, Levitz M, Stattin P, Berrino F, Hallmans G, Kaaks R, Toniolo P, Zeleniuch-Jacquotte A (2004) Circulating levels of sex steroid hormones and risk of endometrial cancer in postmenopausal women. Int J Cancer 108:425-432
-
(2004)
Int J Cancer
, vol.108
, pp. 425-432
-
-
Lukanova, A.1
Lundin, E.2
Micheli, A.3
Arslan, A.4
Ferrari, P.5
Rinaldi, S.6
Krogh, V.7
Lenner, P.8
Shore, R.E.9
Biessy, C.10
Muti, P.11
Riboli, E.12
Koenig, K.L.13
Levitz, M.14
Stattin, P.15
Berrino, F.16
Hallmans, G.17
Kaaks, R.18
Toniolo, P.19
Zeleniuch-Jacquotte, A.20
more..
-
71
-
-
0034993363
-
Analysis and characteristics of multiple types of human 17beta-hydroxysteroid dehydrogenase
-
Luu-The V (2001) Analysis and characteristics of multiple types of human 17beta-hydroxysteroid dehydrogenase. J Steroid Biochem Mol Biol 76:143-151
-
(2001)
J Steroid Biochem Mol Biol
, vol.76
, pp. 143-151
-
-
Luu-The, V.1
-
72
-
-
31444432288
-
Characterization of type 12 17beta-hydroxysteroid dehydrogenase, an isoform of type 3 17beta-hydroxysteroid dehydrogenase responsible for estradiol formation in women
-
Luu-The V, Tremblay P, Labrie F (2006) Characterization of type 12 17beta-hydroxysteroid dehydrogenase, an isoform of type 3 17beta-hydroxysteroid dehydrogenase responsible for estradiol formation in women. Mol Endocrinol 20:437-443
-
(2006)
Mol Endocrinol
, vol.20
, pp. 437-443
-
-
Luu-The, V.1
Tremblay, P.2
Labrie, F.3
-
73
-
-
0029593494
-
Characteristics of human types 1, 2 and 3 17 beta-hydroxysteroid dehydrogenase activities: Oxidation/reduction and inhibition
-
Luu-The V, Zhang Y, Poirier D, Labrie F (1995) Characteristics of human types 1, 2 and 3 17 beta-hydroxysteroid dehydrogenase activities: Oxidation/reduction and inhibition. J Steroid Biochem Mol Biol 55:581-587
-
(1995)
J Steroid Biochem Mol Biol
, vol.55
, pp. 581-587
-
-
Luu-The, V.1
Zhang, Y.2
Poirier, D.3
Labrie, F.4
-
74
-
-
0026781142
-
Immunohistochemical study of the human 17 beta-hydroxysteroid dehydrogenase and steroid receptors in endometrial adenocarcinoma
-
Maentausta O, Boman K, Isomaa V, Stendahl U, Backstrom T, Vihko R (1992) Immunohistochemical study of the human 17 beta-hydroxysteroid dehydrogenase and steroid receptors in endometrial adenocarcinoma. Cancer 70:1551-1555
-
(1992)
Cancer
, vol.70
, pp. 1551-1555
-
-
Maentausta, O.1
Boman, K.2
Isomaa, V.3
Stendahl, U.4
Backstrom, T.5
Vihko, R.6
-
75
-
-
0025144488
-
Immunological measurement of human 17 betahydroxysteroid dehydrogenase
-
Maentausta O, Peltoketo H, Isomaa V, Jouppila P, Vihko R (1990) Immunological measurement of human 17 betahydroxysteroid dehydrogenase. J Steroid Biochem 36:673-680
-
(1990)
J Steroid Biochem
, vol.36
, pp. 673-680
-
-
Maentausta, O.1
Peltoketo, H.2
Isomaa, V.3
Jouppila, P.4
Vihko, R.5
-
76
-
-
0026333956
-
Immunohistochemical localization of 17 beta-hydroxysteroid dehydrogenase in the human endometrium during the menstrual cycle
-
Maentausta O, Sormunen R, Isomaa V, Lehto VP, Jouppila P, Vihko R (1991) Immunohistochemical localization of 17 beta-hydroxysteroid dehydrogenase in the human endometrium during the menstrual cycle. Lab Invest 65:582-587
-
(1991)
Lab Invest
, vol.65
, pp. 582-587
-
-
Maentausta, O.1
Sormunen, R.2
Isomaa, V.3
Lehto, V.P.4
Jouppila, P.5
Vihko, R.6
-
77
-
-
79955776935
-
17beta-Hydroxysteroid dehydrogenases (17beta-HSDs) as therapeutic targets: Protein structures, functions, and recent progress in inhibitor development
-
Marchais-Oberwinkler S, Henn C, Moller G, Klein T, Negri M, Oster A, Spadaro A, Werth R, Wetzel M, Xu K, Frotscher M, Hartmann RW, Adamski J (2011) 17beta-Hydroxysteroid dehydrogenases (17beta-HSDs) as therapeutic targets: Protein structures, functions, and recent progress in inhibitor development. J Steroid Biochem Mol Biol 125:66-82
-
(2011)
J Steroid Biochem Mol Biol
, vol.125
, pp. 66-82
-
-
Marchais-Oberwinkler, S.1
Henn, C.2
Moller, G.3
Klein, T.4
Negri, M.5
Oster, A.6
Spadaro, A.7
Werth, R.8
Wetzel, M.9
Xu, K.10
Frotscher, M.11
Hartmann, R.W.12
Adamski, J.13
-
78
-
-
0029670229
-
Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell-and tissue-specific expression
-
Miettinen MM, Mustonen MV, Poutanen MH, Isomaa VV, Vihko RK (1996) Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell-and tissue-specific expression. Biochem J 314(Pt 3):839-845
-
(1996)
Biochem J
, vol.314
, Issue.PART 3
, pp. 839-845
-
-
Miettinen, M.M.1
Mustonen, M.V.2
Poutanen, M.H.3
Isomaa, V.V.4
Vihko, R.K.5
-
79
-
-
0035546023
-
Involvement of up-regulation of 17beta-hydroxysteroid dehydrogenase type 1 in maintenance of intratumoral high estradiol levels in postmenopausal breast cancers
-
Miyoshi Y, Ando A, Shiba E, Taguchi T, Tamaki Y, Noguchi S (2001) Involvement of up-regulation of 17beta-hydroxysteroid dehydrogenase type 1 in maintenance of intratumoral high estradiol levels in postmenopausal breast cancers. Int J Cancer 94:685-689
-
(2001)
Int J Cancer
, vol.94
, pp. 685-689
-
-
Miyoshi, Y.1
Ando, A.2
Shiba, E.3
Taguchi, T.4
Tamaki, Y.5
Noguchi, S.6
-
80
-
-
33644894458
-
Multifunctionality of human 17beta-hydroxysteroid dehydrogenases
-
Moeller G, Adamski J (2006) Multifunctionality of human 17beta-hydroxysteroid dehydrogenases. Mol Cell Endocrinol 248:47-55
-
(2006)
Mol Cell Endocrinol
, vol.248
, pp. 47-55
-
-
Moeller, G.1
Adamski, J.2
-
81
-
-
60249089957
-
Integrated view on 17betahydroxysteroid dehydrogenases
-
Moeller G, Adamski J (2009) Integrated view on 17betahydroxysteroid dehydrogenases. Mol Cell Endocrinol 301:7-19
-
(2009)
Mol Cell Endocrinol
, vol.301
, pp. 7-19
-
-
Moeller, G.1
Adamski, J.2
-
82
-
-
0030670460
-
Cell typespecific expression of 17 beta-hydroxysteroid dehydrogenase type 2 in human placenta and fetal liver
-
Moghrabi N, Head JR, Andersson S (1997) Cell typespecific expression of 17 beta-hydroxysteroid dehydrogenase type 2 in human placenta and fetal liver. J Clin Endocrinol Metab 82:3872-3878
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 3872-3878
-
-
Moghrabi, N.1
Head, J.R.2
Andersson, S.3
-
83
-
-
79951838692
-
Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer
-
Mohler JL, Titus MA, Bai S, Kennerley BJ, Lih FB, Tomer KB, Wilson EM (2011) Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer. Cancer Res 71:1486-1496
-
(2011)
Cancer Res
, vol.71
, pp. 1486-1496
-
-
Mohler, J.L.1
Titus, M.A.2
Bai, S.3
Kennerley, B.J.4
Lih, F.B.5
Tomer, K.B.6
Wilson, E.M.7
-
84
-
-
0037470063
-
Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade
-
Moon YA, Horton JD (2003) Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade. J Biol Chem 278:7335-7343
-
(2003)
J Biol Chem
, vol.278
, pp. 7335-7343
-
-
Moon, Y.A.1
Horton, J.D.2
-
85
-
-
60549099416
-
17Betahydroxysteroid dehydrogenase type 12 in human breast carcinoma: A prognostic factor via potential regulation of fatty acid synthesis
-
Nagasaki S, Suzuki T, Miki Y, Akahira J, Kitada K, Ishida T, Handa H, Ohuchi N, Sasano H (2009) 17Betahydroxysteroid dehydrogenase type 12 in human breast carcinoma: A prognostic factor via potential regulation of fatty acid synthesis. Cancer Res 69:1392-1399
-
(2009)
Cancer Res
, vol.69
, pp. 1392-1399
-
-
Nagasaki, S.1
Suzuki, T.2
Miki, Y.3
Akahira, J.4
Kitada, K.5
Ishida, T.6
Handa, H.7
Ohuchi, N.8
Sasano, H.9
-
86
-
-
27944495264
-
Characterization of 17beta-hydroxysteroid dehydrogenase type 4 in human ovarian surface epithelial cells
-
Nagayoshi Y, Ohba T, Yamamoto H, Miyahara Y, Tashiro H, Katabuchi H, Okamura H (2005) Characterization of 17beta-hydroxysteroid dehydrogenase type 4 in human ovarian surface epithelial cells. Mol Hum Reprod 11:615-621
-
(2005)
Mol Hum Reprod
, vol.11
, pp. 615-621
-
-
Nagayoshi, Y.1
Ohba, T.2
Yamamoto, H.3
Miyahara, Y.4
Tashiro, H.5
Katabuchi, H.6
Okamura, H.7
-
87
-
-
68149122351
-
17betahydroxysteroid dehydrogenase type 11 (Pan1b) expression in human prostate cancer
-
Nakamura Y, Suzuki T, Arai Y, Sasano H (2009) 17betahydroxysteroid dehydrogenase type 11 (Pan1b) expression in human prostate cancer. Neoplasma 56:317-320
-
(2009)
Neoplasma
, vol.56
, pp. 317-320
-
-
Nakamura, Y.1
Suzuki, T.2
Arai, Y.3
Sasano, H.4
-
88
-
-
20144389477
-
In situ androgen producing enzymes in human prostate cancer
-
Nakamura Y, Suzuki T, Nakabayashi M, Endoh M, Sakamoto K, Mikami Y, Moriya T, Ito A, Takahashi S, Yamada S, Arai Y, Sasano H (2005) In situ androgen producing enzymes in human prostate cancer. Endocr Relat Cancer 12:101-107
-
(2005)
Endocr Relat Cancer
, vol.12
, pp. 101-107
-
-
Nakamura, Y.1
Suzuki, T.2
Nakabayashi, M.3
Endoh, M.4
Sakamoto, K.5
Mikami, Y.6
Moriya, T.7
Ito, A.8
Takahashi, S.9
Yamada, S.10
Arai, Y.11
Sasano, H.12
-
89
-
-
38649141852
-
Expression in E. coli and tissue distribution of the human homologue of the mouse Ke 6 gene, 17beta-hydroxysteroid dehydrogenase type 8
-
Ohno S, Nishikawa K, Honda Y, Nakajin S (2008) Expression in E. coli and tissue distribution of the human homologue of the mouse Ke 6 gene, 17beta-hydroxysteroid dehydrogenase type 8. Mol Cell Biochem 309:209-215
-
(2008)
Mol Cell Biochem
, vol.309
, pp. 209-215
-
-
Ohno, S.1
Nishikawa, K.2
Honda, Y.3
Nakajin, S.4
-
90
-
-
2542492928
-
The selective estrogen enzyme modulators in breast cancer: A review
-
Pasqualini JR (2004) The selective estrogen enzyme modulators in breast cancer: A review. Biochim Biophys Acta 1654:123-143
-
(2004)
Biochim Biophys Acta
, vol.1654
, pp. 123-143
-
-
Pasqualini, J.R.1
-
91
-
-
0029872530
-
Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre-and postmenopausal breast cancer patients
-
Pasqualini JR, Chetrite G, Blacker C, Feinstein MC, Delalonde L, Talbi M, Maloche C (1996) Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre-and postmenopausal breast cancer patients. J Clin Endocrinol Metab 81:1460-1464
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 1460-1464
-
-
Pasqualini, J.R.1
Chetrite, G.2
Blacker, C.3
Feinstein, M.C.4
Delalonde, L.5
Talbi, M.6
Maloche, C.7
-
92
-
-
0030925341
-
Molecular endocrinology of hydroxysteroid dehydrogenases
-
Penning TM (1997) Molecular endocrinology of hydroxysteroid dehydrogenases. Endocr Rev 18:281-305
-
(1997)
Endocr Rev
, vol.18
, pp. 281-305
-
-
Penning, T.M.1
-
93
-
-
0034287545
-
Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: Functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones
-
Penning TM, Burczynski ME, Jez JM, Hung CF, Lin HK, Ma H, Moore M, Palackal N, Ratnam K (2000) Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: Functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones. Biochem J 351:67-77
-
(2000)
Biochem J
, vol.351
, pp. 67-77
-
-
Penning, T.M.1
Burczynski, M.E.2
Jez, J.M.3
Hung, C.F.4
Lin, H.K.5
Ma, H.6
Moore, M.7
Palackal, N.8
Ratnam, K.9
-
94
-
-
79960738374
-
Steroidogenic enzymes and stem cell markers are upregulated during androgen deprivation in prostate cancer
-
Pfeiffer MJ, Smit FP, Sedelaar JP, Schalken JA (2011) Steroidogenic enzymes and stem cell markers are upregulated during androgen deprivation in prostate cancer. Mol Med 17:657-664
-
(2011)
Mol Med
, vol.17
, pp. 657-664
-
-
Pfeiffer, M.J.1
Smit, F.P.2
Sedelaar, J.P.3
Schalken, J.A.4
-
95
-
-
77955836270
-
17beta-Hydroxysteroid dehydrogenase inhibitors: A patent review
-
Poirier D (2010) 17beta-Hydroxysteroid dehydrogenase inhibitors: A patent review. Expert Opin Ther Pat 20:1123-1145
-
(2010)
Expert Opin Ther Pat
, vol.20
, pp. 1123-1145
-
-
Poirier, D.1
-
96
-
-
79957737745
-
Contribution to the development of inhibitors of 17beta-hydroxysteroid dehydrogenase types 1 and 7: Key tools for studying and treating estrogen-dependent diseases
-
Poirier D (2010) Contribution to the development of inhibitors of 17beta-hydroxysteroid dehydrogenase types 1 and 7: Key tools for studying and treating estrogen-dependent diseases. J Steroid Biochem Mol Biol 125:83-94
-
(2010)
J Steroid Biochem Mol Biol
, vol.125
, pp. 83-94
-
-
Poirier, D.1
-
97
-
-
9444280099
-
Case-control study of endogenous steroid hormones and endometrial cancer
-
Potischman N, Hoover RN, Brinton LA, Siiteri P, Dorgan JF, Swanson CA, Berman ML, Mortel R, Twiggs LB, Barrett RJ, Wilbanks GD, Persky V, Lurain JR (1996) Case-control study of endogenous steroid hormones and endometrial cancer. J Natl Cancer Inst 88:1127-1135
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 1127-1135
-
-
Potischman, N.1
Hoover, R.N.2
Brinton, L.A.3
Siiteri, P.4
Dorgan, J.F.5
Swanson, C.A.6
Berman, M.L.7
Mortel, R.8
Twiggs, L.B.9
Barrett, R.J.10
Wilbanks, G.D.11
Persky, V.12
Lurain, J.R.13
-
98
-
-
77957271811
-
A useful cell system for studying the regulation of 17HSD/ KSR type 2 activity and expression in ovarian epithelial cancer
-
Provost PR, Lima PH, Tremblay Y, Blomquist CH (2010) A useful cell system for studying the regulation of 17HSD/ KSR type 2 activity and expression in ovarian epithelial cancer. J Steroid Biochem Mol Biol 122:295-301
-
(2010)
J Steroid Biochem Mol Biol
, vol.122
, pp. 295-301
-
-
Provost, P.R.1
Lima, P.H.2
Tremblay, Y.3
Blomquist, C.H.4
-
99
-
-
12344334475
-
Steroid signalling in human ovarian surface epithelial cells: The response to interleukin-1alpha determined by microarray analysis
-
Rae MT, Niven D, Ross A, Forster T, Lathe R, Critchley HO, Ghazal P, Hillier SG (2004) Steroid signalling in human ovarian surface epithelial cells: The response to interleukin-1alpha determined by microarray analysis. J Endocrinol 183:19-28
-
(2004)
J Endocrinol
, vol.183
, pp. 19-28
-
-
Rae, M.T.1
Niven, D.2
Ross, A.3
Forster, T.4
Lathe, R.5
Critchley, H.O.6
Ghazal, P.7
Hillier, S.G.8
-
100
-
-
33645835375
-
Developmental model for the pathogenesis of testicular carcinoma in situ: Genetic and environmental aspects
-
Rajpert-De Meyts E (2006) Developmental model for the pathogenesis of testicular carcinoma in situ: Genetic and environmental aspects. Hum Reprod Update 12:303-323
-
(2006)
Hum Reprod Update
, vol.12
, pp. 303-323
-
-
Rajpert-De Meyts, E.1
-
101
-
-
60249095768
-
HSD17B4 overexpression, an independent biomarker of poor patient outcome in prostate cancer
-
Rasiah KK, Gardiner-Garden M, Padilla EJ, Moller G, Kench JG, Alles MC, Eggleton SA, Stricker PD, Adamski J, Sutherland RL, Henshall SM, Hayes VM (2009) HSD17B4 overexpression, an independent biomarker of poor patient outcome in prostate cancer. Mol Cell Endocrinol 301:89-96
-
(2009)
Mol Cell Endocrinol
, vol.301
, pp. 89-96
-
-
Rasiah, K.K.1
Gardiner-Garden, M.2
Padilla, E.J.3
Moller, G.4
Kench, J.G.5
Alles, M.C.6
Eggleton, S.A.7
Stricker, P.D.8
Adamski, J.9
Sutherland, R.L.10
Henshall, S.M.11
Hayes, V.M.12
-
102
-
-
33644909044
-
AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer
-
Rizner TL, Smuc T, Rupreht R, Sinkovec J, Penning TM (2006) AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer. Mol Cell Endocrinol 248:126-135
-
(2006)
Mol Cell Endocrinol
, vol.248
, pp. 126-135
-
-
Rizner, T.L.1
Smuc, T.2
Rupreht, R.3
Sinkovec, J.4
Penning, T.M.5
-
103
-
-
0034284550
-
Therapeutic approaches to bone diseases
-
Rodan GA, Martin TJ (2000) Therapeutic approaches to bone diseases. Science 289:1508-1514
-
(2000)
Science
, vol.289
, pp. 1508-1514
-
-
Rodan, G.A.1
Martin, T.J.2
-
104
-
-
67449155337
-
Estradiol induces type 8 17beta-hydroxysteroid dehydrogenase expression: Crosstalk between estrogen receptor alpha and C/EBPbeta
-
RotinenM, Celay J, AlonsoMM, Arrazola A, Encio I, Villar J (2009) Estradiol induces type 8 17beta-hydroxysteroid dehydrogenase expression: Crosstalk between estrogen receptor alpha and C/EBPbeta. J Endocrinol 200:85-92
-
(2009)
J Endocrinol
, vol.200
, pp. 85-92
-
-
Rotinen, M.1
Celay, J.2
Alonso, M.M.3
Arrazola, A.4
Encio, I.5
Villar, J.6
-
105
-
-
79958063073
-
Transcriptional regulation of type 11 17betahydroxysteroid dehydrogenase expression in prostate cancer cells
-
Rotinen M, Villar J, Celay J, Serrano I, Notario V, Encio I (2011) Transcriptional regulation of type 11 17betahydroxysteroid dehydrogenase expression in prostate cancer cells. Mol Cell Endocrinol 339:45-53
-
(2011)
Mol Cell Endocrinol
, vol.339
, pp. 45-53
-
-
Rotinen, M.1
Villar, J.2
Celay, J.3
Serrano, I.4
Notario, V.5
Encio, I.6
-
106
-
-
33646801655
-
Systemic distribution and tissue localizations of human 17betahydroxysteroid dehydrogenase type 12
-
Sakurai N, Miki Y, Suzuki T, Watanabe K, Narita T, Ando K, Yung TM, Aoki D, Sasano H, Handa H (2006) Systemic distribution and tissue localizations of human 17betahydroxysteroid dehydrogenase type 12. J Steroid Biochem Mol Biol 99:174-181
-
(2006)
J Steroid Biochem Mol Biol
, vol.99
, pp. 174-181
-
-
Sakurai, N.1
Miki, Y.2
Suzuki, T.3
Watanabe, K.4
Narita, T.5
Ando, K.6
Yung, T.M.7
Aoki, D.8
Sasano, H.9
Handa, H.10
-
107
-
-
83455260425
-
The diversity of sex steroid action: Novel functions of hydroxysteroid (17beta) dehydrogenases as revealed by genetically modified mouse models
-
Saloniemi T, Jokela H, Strauss L, Pakarinen P, Poutanen M (2012) The diversity of sex steroid action: Novel functions of hydroxysteroid (17beta) dehydrogenases as revealed by genetically modified mouse models. J Endocrinol 212:27-40
-
(2012)
J Endocrinol
, vol.212
, pp. 27-40
-
-
Saloniemi, T.1
Jokela, H.2
Strauss, L.3
Pakarinen, P.4
Poutanen, M.5
-
108
-
-
35649021759
-
Activation of androgens by hydroxysteroid (17beta) dehydrogenase 1 in vivo as a cause of prenatal masculinization and ovarian benign serous cystadenomas
-
Saloniemi T, Lamminen T, Huhtinen K, Welsh M, Saunders P, Kujari H, Poutanen M (2007) Activation of androgens by hydroxysteroid (17beta) dehydrogenase 1 in vivo as a cause of prenatal masculinization and ovarian benign serous cystadenomas. Mol Endocrinol 21:2627-2636
-
(2007)
Mol Endocrinol
, vol.21
, pp. 2627-2636
-
-
Saloniemi, T.1
Lamminen, T.2
Huhtinen, K.3
Welsh, M.4
Saunders, P.5
Kujari, H.6
Poutanen, M.7
-
109
-
-
0021149871
-
In situ estrogen production via the estrone sulfatase pathway in breast tumors: Relative importance versus the aromatase pathway
-
Santner SJ, Feil PD, Santen RJ (1984) In situ estrogen production via the estrone sulfatase pathway in breast tumors: Relative importance versus the aromatase pathway. J Clin Endocrinol Metab 59:29-33
-
(1984)
J Clin Endocrinol Metab
, vol.59
, pp. 29-33
-
-
Santner, S.J.1
Feil, P.D.2
Santen, R.J.3
-
110
-
-
0029998817
-
17 beta-hydroxysteroid dehydrogenase in common epithelial ovarian tumors
-
Sasano H, Suzuki T, Niikura H, Kaga K, Sato S, Yajima A, Rainey WE, Nagura H (1996) 17 beta-hydroxysteroid dehydrogenase in common epithelial ovarian tumors. Mod Pathol 9:386-391
-
(1996)
Mod Pathol
, vol.9
, pp. 386-391
-
-
Sasano, H.1
Suzuki, T.2
Niikura, H.3
Kaga, K.4
Sato, S.5
Yajima, A.6
Rainey, W.E.7
Nagura, H.8
-
111
-
-
0034710928
-
Prostate formation in a marsupial is mediated by the testicular androgen 5 alpha-androstane-3 alpha,17 beta-diol
-
Shaw G, Renfree MB, Leihy MW, Shackleton CH, Roitman E, Wilson JD (2000) Prostate formation in a marsupial is mediated by the testicular androgen 5 alpha-androstane-3 alpha,17 beta-diol. Proc Natl Acad Sci U S A 97:12256-12259
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12256-12259
-
-
Shaw, G.1
Renfree, M.B.2
Leihy, M.W.3
Shackleton, C.H.4
Roitman, E.5
Wilson, J.D.6
-
112
-
-
79955787202
-
The stimulation of HSD17B7 expression by estradiol provides a powerful feed-forward mechanism for estradiol biosynthesis in breast cancer cells
-
Shehu A, Albarracin C, Sangeeta Devi Y, Luther K, Halperin J, Le J, Mao J, Duan RW, Frasor J, Gibori G (2011) The stimulation of HSD17B7 expression by estradiol provides a powerful feed-forward mechanism for estradiol biosynthesis in breast cancer cells. Mol Endocrinol 25:754-766
-
(2011)
Mol Endocrinol
, vol.25
, pp. 754-766
-
-
Shehu, A.1
Albarracin, C.2
Sangeeta Devi, Y.3
Luther, K.4
Halperin, J.5
Le J Mao, J.6
Duan, R.W.7
Frasor, J.8
Gibori, G.9
-
113
-
-
33644898089
-
Expression analysis of estrogen-metabolizing enzymes in human endometrial cancer
-
Smuc T, Rupreht R, Sinkovec J, Adamski J, Rizner TL (2006) Expression analysis of estrogen-metabolizing enzymes in human endometrial cancer. Mol Cell Endocrinol 248:114-117
-
(2006)
Mol Cell Endocrinol
, vol.248
, pp. 114-117
-
-
Smuc, T.1
Rupreht, R.2
Sinkovec, J.3
Adamski, J.4
Rizner, T.L.5
-
114
-
-
33748177287
-
Expression of aromatase and 17beta-hydroxysteroid dehydrogenase types 1, 7 and 12 in breast cancer. An immunocytochemical study
-
Song D, Liu G, Luu-The V, Zhao D, Wang L, Zhang H, Xueling G, Li S, Desy L, Labrie F, Pelletier G (2006) Expression of aromatase and 17beta- hydroxysteroid dehydrogenase types 1, 7 and 12 in breast cancer. An immunocytochemical study. J Steroid Biochem Mol Biol 101:136-144
-
(2006)
J Steroid Biochem Mol Biol
, vol.101
, pp. 136-144
-
-
Song, D.1
Liu, G.2
Luu-The, V.3
Zhao, D.4
Wang, L.5
Zhang, H.6
Xueling, G.7
Li, S.8
Desy, L.9
Labrie, F.10
Pelletier, G.11
-
115
-
-
0031732665
-
Activity and gene expression of 17beta-hydroxysteroid dehydrogenase type I in primary cultures of epithelial and stromal cells derived from normal and tumourous human breast tissue: The role of IL-8
-
Speirs V, Green AR, Atkin SL (1998) Activity and gene expression of 17beta-hydroxysteroid dehydrogenase type I in primary cultures of epithelial and stromal cells derived from normal and tumourous human breast tissue: The role of IL-8. J Steroid Biochem Mol Biol 67:267-274
-
(1998)
J Steroid Biochem Mol Biol
, vol.67
, pp. 267-274
-
-
Speirs, V.1
Green, A.R.2
Atkin, S.L.3
-
116
-
-
33645056171
-
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
-
Stanbrough M, Bubley GJ, Ross K, Golub TR, Rubin MA, Penning TM, Febbo PG, Balk SP (2006) Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Res 66:2815-2825
-
(2006)
Cancer Res
, vol.66
, pp. 2815-2825
-
-
Stanbrough, M.1
Bubley, G.J.2
Ross, K.3
Golub, T.R.4
Rubin, M.A.5
Penning, T.M.6
Febbo, P.G.7
Balk, S.P.8
-
117
-
-
0034132569
-
17Beta-hydroxysteroid dehydrogenase type 1 and type 2 in human breast carcinoma: A correlation to clinicopathological parameters
-
Suzuki T, Moriya T, Ariga N, Kaneko C, Kanazawa M, Sasano H (2000) 17Beta-hydroxysteroid dehydrogenase type 1 and type 2 in human breast carcinoma: A correlation to clinicopathological parameters. Br J Cancer 82:518-523
-
(2000)
Br J Cancer
, vol.82
, pp. 518-523
-
-
Suzuki, T.1
Moriya, T.2
Ariga, N.3
Kaneko, C.4
Kanazawa, M.5
Sasano, H.6
-
118
-
-
77949895509
-
Steroid hormone metabolizing enzymes in benign and malignant human bone tumors
-
Svoboda M, Hamilton G, Thalhammer T (2010) Steroid hormone metabolizing enzymes in benign and malignant human bone tumors. Expert Opin Drug Metab Toxicol 6:427-437
-
(2010)
Expert Opin Drug Metab Toxicol
, vol.6
, pp. 427-437
-
-
Svoboda, M.1
Hamilton, G.2
Thalhammer, T.3
-
119
-
-
0038745685
-
Production, purification, and functional analysis of recombinant human and mouse 17beta-hydroxysteroid dehydrogenase type 7
-
Torn S, Nokelainen P, Kurkela R, Pulkka A, Menjivar M, Ghosh S, Coca-Prados M, Peltoketo H, Isomaa V, Vihko P (2003) Production, purification, and functional analysis of recombinant human and mouse 17beta-hydroxysteroid dehydrogenase type 7. Biochem Biophys Res Commun 305:37-45
-
(2003)
Biochem Biophys Res Commun
, vol.305
, pp. 37-45
-
-
Torn, S.1
Nokelainen, P.2
Kurkela, R.3
Pulkka, A.4
Menjivar, M.5
Ghosh, S.6
Coca-Prados, M.7
Peltoketo, H.8
Isomaa, V.9
Vihko, P.10
-
120
-
-
33746602208
-
A molecular correlate to the Gleason grading system for prostate adenocarcinoma
-
True L, Coleman I, Hawley S, Huang CY, Gifford D, Coleman R, Beer TM, Gelmann E, Datta M, Mostaghel E, Knudsen B, Lange P, Vessella R, Lin D, Hood L, Nelson PS (2006) A molecular correlate to the Gleason grading system for prostate adenocarcinoma. Proc Natl Acad Sci U S A 103:10991-10996
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10991-10996
-
-
True, L.1
Coleman, I.2
Hawley, S.3
Huang, C.Y.4
Gifford, D.5
Coleman, R.6
Beer, T.M.7
Gelmann, E.8
Datta, M.9
Mostaghel, E.10
Knudsen, B.11
Lange, P.12
Vessella, R.13
Lin, D.14
Hood, L.15
Nelson, P.S.16
-
121
-
-
17844371322
-
The analyses of 17beta-hydroxysteroid dehydrogenase isozymes in human endometrial hyperplasia and carcinoma
-
Utsunomiya H, Suzuki T, Kaneko C, Takeyama J, Nakamura J, Kimura K, Yoshihama M, Harada N, Ito K, Konno R, Sato S, Okamura K, Sasano H (2001) The analyses of 17beta-hydroxysteroid dehydrogenase isozymes in human endometrial hyperplasia and carcinoma. J Clin Endocrinol Metab 86:3436-3443
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 3436-3443
-
-
Utsunomiya, H.1
Suzuki, T.2
Kaneko, C.3
Takeyama, J.4
Nakamura, J.5
Kimura, K.6
Yoshihama, M.7
Harada, N.8
Ito, K.9
Konno, R.10
Sato, S.11
Okamura, K.12
Sasano, H.13
-
122
-
-
0038470011
-
The correlation between the response to progestogen treatment and the expression of progesterone receptor B and 17betahydroxysteroid dehydrogenase type 2 in human endometrial carcinoma
-
Utsunomiya H, Suzuki T, Ito K, Moriya T, Konno R, Sato S, Yaegashi N, Okamura K, Sasano H (2003) The correlation between the response to progestogen treatment and the expression of progesterone receptor B and 17betahydroxysteroid dehydrogenase type 2 in human endometrial carcinoma. Clin Endocrinol (Oxf) 58:696-703
-
(2003)
Clin Endocrinol (Oxf
, vol.58
, pp. 696-703
-
-
Utsunomiya, H.1
Suzuki, T.2
Ito, K.3
Moriya, T.4
Konno, R.5
Sato, S.6
Yaegashi, N.7
Okamura, K.8
Sasano, H.9
-
123
-
-
4444265838
-
Steroid sulfatase and estrogen sulfotransferase in human endometrial carcinoma
-
Utsunomiya H, Ito K, Suzuki T, Kitamura T, Kaneko C, Nakata T, Niikura H, Okamura K, Yaegashi N, Sasano H (2004) Steroid sulfatase and estrogen sulfotransferase in human endometrial carcinoma. Clin Cancer Res 10:5850-5856
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5850-5856
-
-
Utsunomiya, H.1
Ito, K.2
Suzuki, T.3
Kitamura, T.4
Kaneko, C.5
Nakata, T.6
Niikura, H.7
Okamura, K.8
Yaegashi, N.9
Sasano, H.10
-
124
-
-
60249101058
-
The design of novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors
-
Vicker N, Sharland CM, Heaton WB, Gonzalez AM, Bailey HV, Smith A, Springall JS, Day JM, Tutill HJ, Reed MJ, Purohit A, Potter BV (2009) The design of novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors. Mol Cell Endocrinol 301:259-265
-
(2009)
Mol Cell Endocrinol
, vol.301
, pp. 259-265
-
-
Vicker, N.1
Sharland, C.M.2
Heaton, W.B.3
Gonzalez, A.M.4
Bailey, H.V.5
Smith, A.6
Springall, J.S.7
Day, J.M.8
Tutill, H.J.9
Reed, M.J.10
Purohit, A.11
Potter, B.V.12
-
125
-
-
0020609478
-
Cytosol and nuclear estrogen and progestin receptors and 17 betahydroxysteroid dehydrogenase activity in non-diseased tissue and in benign and malignant tumors of the human ovary
-
Vierikko P, Kauppila A, Vihko R (1983) Cytosol and nuclear estrogen and progestin receptors and 17 betahydroxysteroid dehydrogenase activity in non-diseased tissue and in benign and malignant tumors of the human ovary. Int J Cancer 32:413-422
-
(1983)
Int J Cancer
, vol.32
, pp. 413-422
-
-
Vierikko, P.1
Kauppila, A.2
Vihko, R.3
-
126
-
-
42049098597
-
Expression of androgen receptor through androgen-converting enzymes is associated with biological aggressiveness in prostate cancer
-
Wako K, Kawasaki T, Yamana K, Suzuki K, Jiang S, Umezu H, Nishiyama T, Takahashi K, Hamakubo T, Kodama T, Naito M (2008) Expression of androgen receptor through androgen-converting enzymes is associated with biological aggressiveness in prostate cancer. J Clin Pathol 61:448-454
-
(2008)
J Clin Pathol
, vol.61
, pp. 448-454
-
-
Wako, K.1
Kawasaki, T.2
Yamana, K.3
Suzuki, K.4
Jiang, S.5
Umezu, H.6
Nishiyama, T.7
Takahashi, K.8
Hamakubo, T.9
Kodama, T.10
Naito, M.11
-
127
-
-
0030960547
-
The epidemiology of thyroid disease and implications for screening
-
Wang C, Crapo LM (1997) The epidemiology of thyroid disease and implications for screening. Endocrinol Metab Clin North Am 26:189-218
-
(1997)
Endocrinol Metab Clin North Am
, vol.26
, pp. 189-218
-
-
Wang, C.1
Crapo, L.M.2
-
128
-
-
0037317265
-
5alphaandrostane-3alpha,17beta-diol is formed in tammar wallaby pouch young testes by a pathway involving 5alphapregnane-3alpha,17alpha-diol-20-one as a key intermediate
-
Wilson JD, Auchus RJ, Leihy MW, Guryev OL, Estabrook RW, Osborn SM, Shaw G, Renfree MB (2003) 5alphaandrostane-3alpha,17beta-diol is formed in tammar wallaby pouch young testes by a pathway involving 5alphapregnane-3alpha,17alpha- diol-20-one as a key intermediate. Endocrinology 144:575-580
-
(2003)
Endocrinology
, vol.144
, pp. 575-580
-
-
Wilson, J.D.1
Auchus, R.J.2
Leihy, M.W.3
Guryev, O.L.4
Estabrook, R.W.5
Osborn, S.M.6
Shaw, G.7
Renfree, M.B.8
-
129
-
-
17744376755
-
Postmenopausal endogenous oestrogens and risk of endometrial cancer: Results of a prospective study
-
Zeleniuch-Jacquotte A, Akhmedkhanov A, Kato I, Koenig KL, Shore RE, Kim MY, Levitz M, Mittal KR, Raju U, Banerjee S, Toniolo P (2001) Postmenopausal endogenous oestrogens and risk of endometrial cancer: Results of a prospective study. Br J Cancer 84:975-981
-
(2001)
Br J Cancer
, vol.84
, pp. 975-981
-
-
Zeleniuch-Jacquotte, A.1
Akhmedkhanov, A.2
Kato, I.3
Koenig, K.L.4
Shore, R.E.5
Kim, M.Y.6
Levitz, M.7
Mittal, K.R.8
Raju, U.9
Banerjee, S.10
Toniolo, P.11
-
130
-
-
18644382720
-
Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer
-
Zha S, Ferdinandusse S, Hicks JL, Denis S, Dunn TA, Wanders RJ, Luo J, De Marzo AM, Isaacs WB (2005) Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer. Prostate 63:316-323
-
(2005)
Prostate
, vol.63
, pp. 316-323
-
-
Zha, S.1
Ferdinandusse, S.2
Hicks, J.L.3
Denis, S.4
Dunn, T.A.5
Wanders, R.J.6
Luo, J.7
De Marzo, A.M.8
Isaacs, W.B.9
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