Design and synthesis of bisubstrate inhibitors of type 1 17β-hydroxysteroid dehydrogenase: Overview and perspectives

European Journal of Medicinal Chemistry

Volumn 43, Issue 11, 2008, Pages 2298-2306

  Fournier, D ^a   Poirier, D ^a   Mazumdar, M ^a   Lin, S X ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Cancer; Enzyme; Estradiol; Hydroxysteroid dehydrogenase; Inhibitor; Steroid

Indexed keywords

EM 1745; ESTRADIOL; ESTRONE; TESTOSTERONE 17BETA DEHYDROGENASE; UNCLASSIFIED DRUG;

CHEMICAL STRUCTURE; DRUG ACTIVITY; DRUG DESIGN; DRUG MECHANISM; DRUG SYNTHESIS; HUMAN; HUMAN CELL; SHORT SURVEY;

17-HYDROXYSTEROID DEHYDROGENASES; CRYSTALLIZATION; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; SUBSTRATE SPECIFICITY;

EID: 54049116349     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.01.044     Document Type: Short Survey

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