-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, (2011) Center MM, Ferlay J, Ward E, et al (2011) Global cancer statistics. CA Cancer J Clin 61: 69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
-
2
-
-
38049160169
-
Time trends in incidence and prognosis of primary liver cancer and liver metastases of unknown origin in a Danish region, 1985-2004
-
Erichsen R, Jepsen P, Jacobsen J, Norgaard M, Vilstrup H, et al. (2008) Time trends in incidence and prognosis of primary liver cancer and liver metastases of unknown origin in a Danish region, 1985-2004. Eur J Gastroenterol Hepatol 20: 104-110.
-
(2008)
Eur J Gastroenterol Hepatol
, vol.20
, pp. 104-110
-
-
Erichsen, R.1
Jepsen, P.2
Jacobsen, J.3
Norgaard, M.4
Vilstrup, H.5
-
4
-
-
79953002209
-
A multicenter retrospective study on clinical characteristics, treatment patterns, and outcome in elderly patients with hepatocellular carcinoma
-
Kozyreva ON, Chi D, Clark JW, Wang H, Theall KP, et al. (2011) A multicenter retrospective study on clinical characteristics, treatment patterns, and outcome in elderly patients with hepatocellular carcinoma. Oncologist 16: 310-318.
-
(2011)
Oncologist
, vol.16
, pp. 310-318
-
-
Kozyreva, O.N.1
Chi, D.2
Clark, J.W.3
Wang, H.4
Theall, K.P.5
-
5
-
-
83555162579
-
Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): an emerging field for advanced technologies
-
Marquardt JU, Galle PR, Teufel A, (2012) Molecular diagnosis and therapy of hepatocellular carcinoma (HCC): an emerging field for advanced technologies. J Hepatol 56: 267-275.
-
(2012)
J Hepatol
, vol.56
, pp. 267-275
-
-
Marquardt, J.U.1
Galle, P.R.2
Teufel, A.3
-
6
-
-
0033887456
-
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
-
Frye RA, (2000) Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem Biophys Res Commun 273: 793-798.
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 793-798
-
-
Frye, R.A.1
-
7
-
-
34547875013
-
NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs
-
Vaquero A, Sternglanz R, Reinberg D, (2007) NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs. Oncogene 26: 5505-5520.
-
(2007)
Oncogene
, vol.26
, pp. 5505-5520
-
-
Vaquero, A.1
Sternglanz, R.2
Reinberg, D.3
-
8
-
-
33845933657
-
Sirtuins: a conserved key unlocking AceCS activity
-
North BJ, Sinclair DA, (2007) Sirtuins: a conserved key unlocking AceCS activity. Trends Biochem Sci 32: 1-4.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 1-4
-
-
North, B.J.1
Sinclair, D.A.2
-
10
-
-
77955608578
-
Sirtuin family: a link to metabolic signaling and senescence
-
Kyrylenko S, Baniahmad A, (2010) Sirtuin family: a link to metabolic signaling and senescence. Curr Med Chem 17: 2921-2932.
-
(2010)
Curr Med Chem
, vol.17
, pp. 2921-2932
-
-
Kyrylenko, S.1
Baniahmad, A.2
-
11
-
-
77953287165
-
Mitochondrial sirtuins
-
Huang JY, Hirschey MD, Shimazu T, Ho L, Verdin E, (2010) Mitochondrial sirtuins. Biochim Biophys Acta 1804: 1645-1651.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 1645-1651
-
-
Huang, J.Y.1
Hirschey, M.D.2
Shimazu, T.3
Ho, L.4
Verdin, E.5
-
12
-
-
0037108799
-
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
-
Onyango P, Celic I, McCaffery JM, Boeke JD, Feinberg AP, (2002) SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci U S A 99: 13653-13658.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 13653-13658
-
-
Onyango, P.1
Celic, I.2
McCaffery, J.M.3
Boeke, J.D.4
Feinberg, A.P.5
-
13
-
-
63749099484
-
A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein
-
Cooper HM, Huang JY, Verdin E, Spelbrink JN, (2009) A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein. PLoS One 4: e4986.
-
(2009)
PLoS One
, vol.4
-
-
Cooper, H.M.1
Huang, J.Y.2
Verdin, E.3
Spelbrink, J.N.4
-
14
-
-
78649509214
-
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production
-
Shimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, et al. (2010) SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab 12: 654-661.
-
(2010)
Cell Metab
, vol.12
, pp. 654-661
-
-
Shimazu, T.1
Hirschey, M.D.2
Hua, L.3
Dittenhafer-Reed, K.E.4
Schwer, B.5
-
15
-
-
84860809347
-
SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging
-
Giralt A, Villarroya F, (2012) SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging. Biochem J 444: 1-10.
-
(2012)
Biochem J
, vol.444
, pp. 1-10
-
-
Giralt, A.1
Villarroya, F.2
-
16
-
-
33750212896
-
Altered sirtuin expression is associated with node-positive breast cancer
-
Ashraf N, Zino S, Macintyre A, Kingsmore D, Payne AP, et al. (2006) Altered sirtuin expression is associated with node-positive breast cancer. Br J Cancer 95: 1056-1061.
-
(2006)
Br J Cancer
, vol.95
, pp. 1056-1061
-
-
Ashraf, N.1
Zino, S.2
Macintyre, A.3
Kingsmore, D.4
Payne, A.P.5
-
17
-
-
74049094817
-
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
-
Kim HS, Patel K, Muldoon-Jacobs K, Bisht KS, Aykin-Burns N, et al. (2010) SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell 17: 41-52.
-
(2010)
Cancer Cell
, vol.17
, pp. 41-52
-
-
Kim, H.S.1
Patel, K.2
Muldoon-Jacobs, K.3
Bisht, K.S.4
Aykin-Burns, N.5
-
18
-
-
79953799195
-
Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer
-
Alhazzazi TY, Kamarajan P, Joo N, Huang JY, Verdin E, et al. (2011) Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer. Cancer 117: 1670-1678.
-
(2011)
Cancer
, vol.117
, pp. 1670-1678
-
-
Alhazzazi, T.Y.1
Kamarajan, P.2
Joo, N.3
Huang, J.Y.4
Verdin, E.5
-
19
-
-
84862689176
-
Sirt3 inhibits hepatocellular carcinoma cell growth through reducing Mdm2-mediated p53 degradation
-
Zhang YY, Zhou LM, (2012) Sirt3 inhibits hepatocellular carcinoma cell growth through reducing Mdm2-mediated p53 degradation. Biochem Biophys Res Commun 423: 26-31.
-
(2012)
Biochem Biophys Res Commun
, vol.423
, pp. 26-31
-
-
Zhang, Y.Y.1
Zhou, L.M.2
-
20
-
-
84862783937
-
Increased expression of ZBP-89 and its prognostic significance in hepatocellular carcinoma
-
Zhang CZ, Cao Y, Yun JP, Chen GG, Lai PB, (2012) Increased expression of ZBP-89 and its prognostic significance in hepatocellular carcinoma. Histopathology 60: 1114-1124.
-
(2012)
Histopathology
, vol.60
, pp. 1114-1124
-
-
Zhang, C.Z.1
Cao, Y.2
Yun, J.P.3
Chen, G.G.4
Lai, P.B.5
-
21
-
-
84861786781
-
Decreased selenium-binding protein 1 enhances glutathione peroxidase 1 activity and downregulates HIF-1alpha to promote hepatocellular carcinoma invasiveness
-
Huang C, Ding G, Gu C, Zhou J, Kuang M, et al. (2012) Decreased selenium-binding protein 1 enhances glutathione peroxidase 1 activity and downregulates HIF-1alpha to promote hepatocellular carcinoma invasiveness. Clin Cancer Res 18: 3042-3053.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3042-3053
-
-
Huang, C.1
Ding, G.2
Gu, C.3
Zhou, J.4
Kuang, M.5
-
22
-
-
77954153940
-
Decreased expression of PinX1 protein is correlated with tumor development and is a new independent poor prognostic factor in ovarian carcinoma
-
Cai MY, Zhang B, He WP, Yang GF, Rao HL, et al. (2010) Decreased expression of PinX1 protein is correlated with tumor development and is a new independent poor prognostic factor in ovarian carcinoma. Cancer Sci 101: 1543-1549.
-
(2010)
Cancer Sci
, vol.101
, pp. 1543-1549
-
-
Cai, M.Y.1
Zhang, B.2
He, W.P.3
Yang, G.F.4
Rao, H.L.5
-
23
-
-
34848842992
-
Selecting immunohistochemical cut-off scores for novel biomarkers of progression and survival in colorectal cancer
-
Zlobec I, Steele R, Terracciano L, Jass JR, Lugli A, (2007) Selecting immunohistochemical cut-off scores for novel biomarkers of progression and survival in colorectal cancer. J Clin Pathol 60: 1112-1116.
-
(2007)
J Clin Pathol
, vol.60
, pp. 1112-1116
-
-
Zlobec, I.1
Steele, R.2
Terracciano, L.3
Jass, J.R.4
Lugli, A.5
-
24
-
-
84864359563
-
Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study
-
Shen Q, Fan J, Yang XR, Tan Y, Zhao W, et al. (2012) Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study. Lancet Oncol 13: 817-826.
-
(2012)
Lancet Oncol
, vol.13
, pp. 817-826
-
-
Shen, Q.1
Fan, J.2
Yang, X.R.3
Tan, Y.4
Zhao, W.5
-
25
-
-
84861223639
-
Serum anti-Ku86 is a potential biomarker for early detection of hepatitis C virus-related hepatocellular carcinoma
-
Nomura F, Sogawa K, Noda K, Seimiya M, Matsushita K, et al. (2012) Serum anti-Ku86 is a potential biomarker for early detection of hepatitis C virus-related hepatocellular carcinoma. Biochem Biophys Res Commun 421: 837-843.
-
(2012)
Biochem Biophys Res Commun
, vol.421
, pp. 837-843
-
-
Nomura, F.1
Sogawa, K.2
Noda, K.3
Seimiya, M.4
Matsushita, K.5
-
26
-
-
84555202717
-
Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma
-
Zhou J, Yu L, Gao X, Hu J, Wang J, et al. (2011) Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma. J Clin Oncol 29: 4781-4788.
-
(2011)
J Clin Oncol
, vol.29
, pp. 4781-4788
-
-
Zhou, J.1
Yu, L.2
Gao, X.3
Hu, J.4
Wang, J.5
-
27
-
-
84879069878
-
aOverexpression of forkhead box C1 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma
-
Xia L, Huang W, Tian D, Zhu H, Qi X, et al. (2012) aOverexpression of forkhead box C1 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma. Hepatology.
-
(2012)
Hepatology
-
-
Xia, L.1
Huang, W.2
Tian, D.3
Zhu, H.4
Qi, X.5
-
28
-
-
80053974116
-
Clinical and prognostic implications of plasma insulin-like growth factor-1 and vascular endothelial growth factor in patients with hepatocellular carcinoma
-
Kaseb AO, Morris JS, Hassan MM, Siddiqui AM, Lin E, et al. (2011) Clinical and prognostic implications of plasma insulin-like growth factor-1 and vascular endothelial growth factor in patients with hepatocellular carcinoma. J Clin Oncol 29: 3892-3899.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3892-3899
-
-
Kaseb, A.O.1
Morris, J.S.2
Hassan, M.M.3
Siddiqui, A.M.4
Lin, E.5
-
29
-
-
78650436438
-
The microRNA miR-139 suppresses metastasis and progression of hepatocellular carcinoma by down-regulating Rho-kinase 2
-
Wong CC, Wong CM, Tung EK, Au SL, Lee JM, et al. (2011) The microRNA miR-139 suppresses metastasis and progression of hepatocellular carcinoma by down-regulating Rho-kinase 2. Gastroenterology 140: 322-331.
-
(2011)
Gastroenterology
, vol.140
, pp. 322-331
-
-
Wong, C.C.1
Wong, C.M.2
Tung, E.K.3
Au, S.L.4
Lee, J.M.5
-
30
-
-
79957580468
-
Clinical implications of DNA methylation in hepatocellular carcinoma
-
Sceusi EL, Loose DS, Wray CJ, (2011) Clinical implications of DNA methylation in hepatocellular carcinoma. HPB (Oxford) 13: 369-376.
-
(2011)
HPB (Oxford)
, vol.13
, pp. 369-376
-
-
Sceusi, E.L.1
Loose, D.S.2
Wray, C.J.3
-
31
-
-
77957361278
-
Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors
-
Hernandez-Vargas H, Lambert MP, Le Calvez-Kelm F, Gouysse G, McKay-Chopin S, et al. (2010) Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors. PLoS One 5: e9749.
-
(2010)
PLoS One
, vol.5
-
-
Hernandez-Vargas, H.1
Lambert, M.P.2
Le Calvez-Kelm, F.3
Gouysse, G.4
McKay-Chopin, S.5
-
32
-
-
80053284820
-
Prediction of posthepatectomy recurrence of hepatocellular carcinoma by circulating cancer stem cells: a prospective study
-
Fan ST, Yang ZF, Ho DW, Ng MN, Yu WC, et al. (2011) Prediction of posthepatectomy recurrence of hepatocellular carcinoma by circulating cancer stem cells: a prospective study. Ann Surg 254: 569-576.
-
(2011)
Ann Surg
, vol.254
, pp. 569-576
-
-
Fan, S.T.1
Yang, Z.F.2
Ho, D.W.3
Ng, M.N.4
Yu, W.C.5
-
34
-
-
79957441575
-
SIRT3 and cancer: tumor promoter or suppressor?
-
Alhazzazi TY, Kamarajan P, Verdin E, Kapila YL, (2011) SIRT3 and cancer: tumor promoter or suppressor? Biochim Biophys Acta 1816: 80-88.
-
(2011)
Biochim Biophys Acta
, vol.1816
, pp. 80-88
-
-
Alhazzazi, T.Y.1
Kamarajan, P.2
Verdin, E.3
Kapila, Y.L.4
-
35
-
-
77956295588
-
p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylase
-
Li S, Banck M, Mujtaba S, Zhou MM, Sugrue MM, et al. (2010) p53-induced growth arrest is regulated by the mitochondrial SirT3 deacetylase. PLoS One 5: e10486.
-
(2010)
PLoS One
, vol.5
-
-
Li, S.1
Banck, M.2
Mujtaba, S.3
Zhou, M.M.4
Sugrue, M.M.5
-
36
-
-
53549105529
-
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
-
Sundaresan NR, Samant SA, Pillai VB, Rajamohan SB, Gupta MP, (2008) SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol 28: 6384-6401.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6384-6401
-
-
Sundaresan, N.R.1
Samant, S.A.2
Pillai, V.B.3
Rajamohan, S.B.4
Gupta, M.P.5
-
37
-
-
36849002444
-
SIRT3 is pro-apoptotic and participates in distinct basal apoptotic pathways
-
Allison SJ, Milner J, (2007) SIRT3 is pro-apoptotic and participates in distinct basal apoptotic pathways. Cell Cycle 6: 2669-2677.
-
(2007)
Cell Cycle
, vol.6
, pp. 2669-2677
-
-
Allison, S.J.1
Milner, J.2
-
38
-
-
84861161546
-
SIRT3 is a mitochondrial tumor suppressor: a scientific tale that connects aberrant cellular ROS, the Warburg effect, and carcinogenesis
-
Haigis MC, Deng CX, Finley LW, Kim HS, Gius D, (2012) SIRT3 is a mitochondrial tumor suppressor: a scientific tale that connects aberrant cellular ROS, the Warburg effect, and carcinogenesis. Cancer Res 72: 2468-2472.
-
(2012)
Cancer Res
, vol.72
, pp. 2468-2472
-
-
Haigis, M.C.1
Deng, C.X.2
Finley, L.W.3
Kim, H.S.4
Gius, D.5
-
39
-
-
77955347446
-
Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis
-
Kong X, Wang R, Xue Y, Liu X, Zhang H, et al. (2010) Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis. PLoS One 5: e11707.
-
(2010)
PLoS One
, vol.5
-
-
Kong, X.1
Wang, R.2
Xue, Y.3
Liu, X.4
Zhang, H.5
-
40
-
-
53449083751
-
SIRT1 expression is associated with poor prognosis of diffuse large B-cell lymphoma
-
Jang KY, Hwang SH, Kwon KS, Kim KR, Choi HN, et al. (2008) SIRT1 expression is associated with poor prognosis of diffuse large B-cell lymphoma. Am J Surg Pathol 32: 1523-1531.
-
(2008)
Am J Surg Pathol
, vol.32
, pp. 1523-1531
-
-
Jang, K.Y.1
Hwang, S.H.2
Kwon, K.S.3
Kim, K.R.4
Choi, H.N.5
-
41
-
-
67650348173
-
Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma
-
Cha EJ, Noh SJ, Kwon KS, Kim CY, Park BH, et al. (2009) Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma. Clin Cancer Res 15: 4453-4459.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4453-4459
-
-
Cha, E.J.1
Noh, S.J.2
Kwon, K.S.3
Kim, C.Y.4
Park, B.H.5
-
42
-
-
84880308453
-
Expression of SIRT1 is associated with lymph node metastasis and poor prognosis in both operable triple-negative and non-triple-negative breast cancer
-
Wu M, Wei W, Xiao X, Guo J, Xie X, et al. (2012) Expression of SIRT1 is associated with lymph node metastasis and poor prognosis in both operable triple-negative and non-triple-negative breast cancer. Med Oncol.
-
(2012)
Med Oncol.
-
-
Wu, M.1
Wei, W.2
Xiao, X.3
Guo, J.4
Xie, X.5
-
43
-
-
84861563201
-
SIRT1 promotes tumorigenesis of hepatocellular carcinoma through PI3K/PTEN/AKT signaling
-
Wang H, Liu H, Chen K, Xiao J, He K, et al. (2012) SIRT1 promotes tumorigenesis of hepatocellular carcinoma through PI3K/PTEN/AKT signaling. Oncol Rep 28: 311-318.
-
(2012)
Oncol Rep
, vol.28
, pp. 311-318
-
-
Wang, H.1
Liu, H.2
Chen, K.3
Xiao, J.4
He, K.5
-
44
-
-
84865143188
-
SIRT1 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma and its expression predicts poor prognosis
-
Chen HC, Jeng YM, Yuan RH, Hsu HC, Chen YL, (2012) SIRT1 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma and its expression predicts poor prognosis. Ann Surg Oncol 19: 2011-2019.
-
(2012)
Ann Surg Oncol
, vol.19
, pp. 2011-2019
-
-
Chen, H.C.1
Jeng, Y.M.2
Yuan, R.H.3
Hsu, H.C.4
Chen, Y.L.5
-
45
-
-
62649152321
-
Kaempferol induces apoptosis in two different cell lines via Akt inactivation, Bax and SIRT3 activation, and mitochondrial dysfunction
-
Marfe G, Tafani M, Indelicato M, Sinibaldi-Salimei P, Reali V, et al. (2009) Kaempferol induces apoptosis in two different cell lines via Akt inactivation, Bax and SIRT3 activation, and mitochondrial dysfunction. J Cell Biochem 106: 643-650.
-
(2009)
J Cell Biochem
, vol.106
, pp. 643-650
-
-
Marfe, G.1
Tafani, M.2
Indelicato, M.3
Sinibaldi-Salimei, P.4
Reali, V.5
|