메뉴 건너뛰기




Volumn 16, Issue 3, 2011, Pages 310-318

A multicenter retrospective study on clinical characteristics, treatment patterns, and outcome in elderly patients with hepatocellular carcinoma

Author keywords

Elderly; Epidemiology; Hepatocellular carcinoma; Survival; Treatment pattern

Indexed keywords

ANTINEOPLASTIC AGENT;

EID: 79953002209     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2010-0223     Document Type: Article
Times cited : (31)

References (33)
  • 1
    • 63049133092 scopus 로고    scopus 로고
    • Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005
    • Altekruse SF, McGlynn KA, Reichman ME. Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005. J Clin Oncol 2009;27:1485-1491.
    • (2009) J Clin Oncol , vol.27 , pp. 1485-1491
    • Altekruse, S.F.1    McGlynn, K.A.2    Reichman, M.E.3
  • 2
    • 59849093175 scopus 로고    scopus 로고
    • Incidence of hepatocellular carcinoma and associated risk factors in hepatitis C-related advanced liver disease
    • HALT-C Trial Group
    • Lok AS, Seeff LB, Morgan TR et al; HALT-C Trial Group. Incidence of hepatocellular carcinoma and associated risk factors in hepatitis C-related advanced liver disease. Gastroenterology. 2009;136:138-148.
    • (2009) Gastroenterology , vol.136 , pp. 138-148
    • Lok, A.S.1    Seeff, L.B.2    Morgan, T.R.3
  • 3
    • 3042843757 scopus 로고    scopus 로고
    • Risk factors for hepatocellular carcinoma in patients with cirrhosis
    • Sarbah SA, Gramlich T, Younoszai A et al. Risk factors for hepatocellular carcinoma in patients with cirrhosis. Dig Dis Sci 2004;49:850-853.
    • (2004) Dig Dis Sci , vol.49 , pp. 850-853
    • Sarbah, S.A.1    Gramlich, T.2    Younoszai, A.3
  • 4
    • 33746514438 scopus 로고    scopus 로고
    • Risk factors for hepatocellular carcinoma in patients with alcoholic or viral C cirrhosis
    • N'Kontchou G, Paries J, Htar MT et al. Risk factors for hepatocellular carcinoma in patients with alcoholic or viral C cirrhosis. Clin Gastroenterol Hepatol 2006;4:1062-1068.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 1062-1068
    • N'Kontchou, G.1    Paries, J.2    Htar, M.T.3
  • 5
    • 0347492085 scopus 로고
    • Bethesda, MD: National Cancer Institute. Available at, Accessed December 1, 2009
    • Horner MJ, Ries LAG, Krapcho M et al. SEER Cancer Statistics Review, 1975-2006. Bethesda, MD: National Cancer Institute. Available at http://seer.cancer.gov/csr/1975_2006/. Accessed December 1, 2009.
    • (1975) SEER Cancer Statistics Review
    • Horner, M.J.1    Ries, L.A.G.2    Krapcho, M.3
  • 6
    • 7044231396 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Recent trends in the United States
    • El-Serag HB. Hepatocellular carcinoma: recent trends in the United States. Gastroenterology 2004;127:S27-S34.
    • (2004) Gastroenterology , vol.127
    • El-Serag, H.B.1
  • 7
    • 33646852746 scopus 로고    scopus 로고
    • The prevalence of hepatitis C virus infection in the United States, 1999 through 2002
    • Armstrong GL, Wasley A, Simard EP et al. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Intern Med 2006;144:705-714.
    • (2006) Ann Intern Med , vol.144 , pp. 705-714
    • Armstrong, G.L.1    Wasley, A.2    Simard, E.P.3
  • 8
    • 34249811186 scopus 로고    scopus 로고
    • Older female cancer patients: Importance, causes, and consequences of undertreatment
    • Bouchardy C, Rapiti E, Blagojevic S et al. Older female cancer patients: importance, causes, and consequences of undertreatment. J Clin Oncol 2007;25:1858-1869.
    • (2007) J Clin Oncol , vol.25 , pp. 1858-1869
    • Bouchardy, C.1    Rapiti, E.2    Blagojevic, S.3
  • 9
    • 39049093871 scopus 로고    scopus 로고
    • Racial disparities in cancer therapy: Did the gap narrow between 1992 and 2002?
    • Gross CP, Smith BD, Wolf E et al. Racial disparities in cancer therapy: did the gap narrow between 1992 and 2002? Cancer 2008;112:900-908.
    • (2008) Cancer , vol.112 , pp. 900-908
    • Gross, C.P.1    Smith, B.D.2    Wolf, E.3
  • 10
    • 0035661915 scopus 로고    scopus 로고
    • Clinical features and treatment of hepatocellular carcinoma in eight patients older than eighty years of age
    • Hazama H, Omagari K, Matsuo I et al. Clinical features and treatment of hepatocellular carcinoma in eight patients older than eighty years of age. Hepatogastroenterology 2001;48:1692-1696.
    • (2001) Hepatogastroenterology , vol.48 , pp. 1692-1696
    • Hazama, H.1    Omagari, K.2    Matsuo, I.3
  • 11
    • 4143094695 scopus 로고    scopus 로고
    • Optimal treatment strategy for elderly patients with hepatocellular carcinoma
    • Dohmen K, Shirahama M, Shigematsu H et al. Optimal treatment strategy for elderly patients with hepatocellular carcinoma. J Gastroenterol Hepatol 2004;19:859-865.
    • (2004) J Gastroenterol Hepatol , vol.19 , pp. 859-865
    • Dohmen, K.1    Shirahama, M.2    Shigematsu, H.3
  • 12
    • 61449206266 scopus 로고    scopus 로고
    • Hepatic resection for hepatocellular carcinoma in the elderly
    • Kaibori M, Matsui K, Ishizaki M et al. Hepatic resection for hepatocellular carcinoma in the elderly. J Surg Oncol 2009;99:154-160.
    • (2009) J Surg Oncol , vol.99 , pp. 154-160
    • Kaibori, M.1    Matsui, K.2    Ishizaki, M.3
  • 13
    • 0027968336 scopus 로고
    • Clinical features of hepatocellular carcinoma in the elderly: A study of 91 patients older than 70 years
    • Nomura F, Ohnishi K, Honda M et al. Clinical features of hepatocellular carcinoma in the elderly: a study of 91 patients older than 70 years. Br J Cancer 1994;70:690-693.
    • (1994) Br J Cancer , vol.70 , pp. 690-693
    • Nomura, F.1    Ohnishi, K.2    Honda, M.3
  • 14
    • 0033199994 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in the elderly: Results of surgical and nonsurgical management
    • Poon RT, Fan ST, Lo CM et al. Hepatocellular carcinoma in the elderly: results of surgical and nonsurgical management. Am J Gastroenterol 1999; 94:2460-2466.
    • (1999) Am J Gastroenterol , vol.94 , pp. 2460-2466
    • Poon, R.T.1    Fan, S.T.2    Lo, C.M.3
  • 15
    • 0032721674 scopus 로고    scopus 로고
    • Chronic liver disease in the extremely elderly of 80 years or more: Clinical characteristics, prognosis and patient survival analysis
    • Hoshida Y, Ikeda K, Kobayashi M et al. Chronic liver disease in the extremely elderly of 80 years or more: clinical characteristics, prognosis and patient survival analysis. J Hepatol 1999;31:860-866.
    • (1999) J Hepatol , vol.31 , pp. 860-866
    • Hoshida, Y.1    Ikeda, K.2    Kobayashi, M.3
  • 16
    • 33747756127 scopus 로고    scopus 로고
    • Clinicopathological features, post-surgical survival and prognostic indicators of elderly patients with hepatocellular carcinoma
    • Zhou L, Rui JA, Wang SB et al. Clinicopathological features, post-surgical survival and prognostic indicators of elderly patients with hepatocellular carcinoma. Eur J Surg Oncol 2006;32:767-772.
    • (2006) Eur J Surg Oncol , vol.32 , pp. 767-772
    • Zhou, L.1    Rui, J.A.2    Wang, S.B.3
  • 17
    • 33845224331 scopus 로고    scopus 로고
    • Age-related comparison of the profiles of patients with hepatocellular carcinoma
    • Fujishima T, Ishikawa T, Shiratori Y et al. Age-related comparison of the profiles of patients with hepatocellular carcinoma. Hepatogastroenterology 2006;53:913-918.
    • (2006) Hepatogastroenterology , vol.53 , pp. 913-918
    • Fujishima, T.1    Ishikawa, T.2    Shiratori, Y.3
  • 18
    • 58749101721 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in the elderly: Clinical characteristics, survival analysis, and prognostic indicators in a cohort of Spanish patients older than 75 years
    • Fernández-Ruiz M, Guerra-Vales JM, Llenas-García J et al. Hepatocellular carcinoma in the elderly: clinical characteristics, survival analysis, and prognostic indicators in a cohort of Spanish patients older than 75 years. Rev Esp Enferm Dig 2008;100:625-631.
    • (2008) Rev Esp Enferm Dig , vol.100 , pp. 625-631
    • Fernández-Ruiz, M.1    Guerra-Vales, J.M.2    Llenas-García, J.3
  • 19
    • 33748035393 scopus 로고    scopus 로고
    • Characteristics at presentation and outcome of hepatocellular carcinoma (HCC) in the elderly.Astudy of the Cancer of the Liver Italian Program (CLIP)
    • Pignata S, Gallo C, Daniele B et al. Characteristics at presentation and outcome of hepatocellular carcinoma (HCC) in the elderly.Astudy of the Cancer of the Liver Italian Program (CLIP). Crit Rev Oncol Hematol 2006;59: 243-249.
    • (2006) Crit Rev Oncol Hematol , vol.59 , pp. 243-249
    • Pignata, S.1    Gallo, C.2    Daniele, B.3
  • 20
    • 0034856294 scopus 로고    scopus 로고
    • Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference
    • Bruix J, Sherman M, Llovet JM et al. Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. J Hepatol 2001;35:421-430.
    • (2001) J Hepatol , vol.35 , pp. 421-430
    • Bruix, J.1    Sherman, M.2    Llovet, J.M.3
  • 21
    • 0033870822 scopus 로고    scopus 로고
    • Geriatric oncology: Challenges for the new century
    • Balducci L. Geriatric oncology: challenges for the new century. Eur J Cancer 2000;36:1741-1754.
    • (2000) Eur J Cancer , vol.36 , pp. 1741-1754
    • Balducci, L.1
  • 22
    • 57749113269 scopus 로고    scopus 로고
    • Analysis of the clinicopathological features of hepatocellular carcinoma in elderly patients
    • Jing-Lin X, Sharma D, Bing-Hui Y et al. Analysis of the clinicopathological features of hepatocellular carcinoma in elderly patients. J Nepal Med Assoc 2008;47:132-135.
    • (2008) J Nepal Med Assoc , vol.47 , pp. 132-135
    • Jing-Lin, X.1    Sharma, D.2    Bing-Hui, Y.3
  • 23
    • 70349427046 scopus 로고    scopus 로고
    • Long-term outcomes and prognostic factors of elderly patients with hepatocellular carcinoma undergoing hepatectomy
    • Huang J, Li BK, Chen GH et al. Long-term outcomes and prognostic factors of elderly patients with hepatocellular carcinoma undergoing hepatectomy. J Gastrointest Surg 2009;13:1627-1635.
    • (2009) J Gastrointest Surg , vol.13 , pp. 1627-1635
    • Huang, J.1    Li, B.K.2    Chen, G.H.3
  • 24
    • 31144479682 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in extremely elderly patients: An analysis of clinical characteristics, prognosis and patient survival
    • Tsukioka G, Kakizaki S, Sohara N et al. Hepatocellular carcinoma in extremely elderly patients: an analysis of clinical characteristics, prognosis and patient survival. World J Gastroenterol 2006;12:48-53.
    • (2006) World J Gastroenterol , vol.12 , pp. 48-53
    • Tsukioka, G.1    Kakizaki, S.2    Sohara, N.3
  • 25
    • 70350519956 scopus 로고    scopus 로고
    • A comparison of outcomes from treating hepatocellular carcinoma by hepatic artery embolization in patients younger or older than 70 years
    • Thornton RH, Covey A, Petre EN et al. A comparison of outcomes from treating hepatocellular carcinoma by hepatic artery embolization in patients younger or older than 70 years. Cancer 2009;115:5000-5006.
    • (2009) Cancer , vol.115 , pp. 5000-5006
    • Thornton, R.H.1    Covey, A.2    Petre, E.N.3
  • 26
    • 33847169509 scopus 로고    scopus 로고
    • Unintentional poisoning deaths-United States, 1999-2004
    • Paulozzi L, Annest J. Unintentional poisoning deaths-United States, 1999-2004. CDC. MMWR 2007;56:93-96.
    • (2007) CDC. MMWR. , vol.56 , pp. 93-96
    • Paulozzi, L.1    Annest, J.2
  • 27
    • 0032879468 scopus 로고    scopus 로고
    • Prognosis of hepatocellular carcinoma: The BCLC staging classification
    • Llovet JM, Bru C, Bruix J. Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin Liver Dis 1999;19:329-338.
    • (1999) Semin Liver Dis , vol.19 , pp. 329-338
    • Llovet, J.M.1    Bru, C.2    Bruix, J.3
  • 28
    • 16244369103 scopus 로고    scopus 로고
    • Prognosis of hepatocellular carcinoma: Comparison of 7 staging systems in an American cohort
    • Marrero JA, Fontana RJ, Barrat A et al. Prognosis of hepatocellular carcinoma: comparison of 7 staging systems in an American cohort. Hepatology 2005;41:707-715.
    • (2005) Hepatology , vol.41 , pp. 707-715
    • Marrero, J.A.1    Fontana, R.J.2    Barrat, A.3
  • 30
    • 79953001398 scopus 로고    scopus 로고
    • Retrospective claims database analysis of elderly compared with nonelderly patients (pts) with newly diagnosed hepatocellular carcinoma (HCC)
    • abstract
    • Sanyal AJ, Moyneur E, Barghout V. Retrospective claims database analysis of elderly compared with nonelderly patients (pts) with newly diagnosed hepatocellular carcinoma (HCC). J Clin Oncol 2009;27:abstract 9552.
    • (2009) J Clin Oncol , vol.27 , pp. 9552
    • Sanyal, A.J.1    Moyneur, E.2    Barghout, V.3
  • 31
    • 33644591430 scopus 로고    scopus 로고
    • Understanding the attitudes of the elderly towards enrolment into cancer clinical trials
    • 34-34
    • Townsley CA, Chan KK, Pond GR et al. Understanding the attitudes of the elderly towards enrolment into cancer clinical trials. BMC Cancer 2006;6: 34-34.
    • (2006) BMC Cancer , vol.6
    • Townsley, C.A.1    Chan, K.K.2    Pond, G.R.3
  • 32
    • 0035148454 scopus 로고    scopus 로고
    • Hepatic resection for hepatocellular carcinoma in the elderly
    • Hanazaki K, Kajikawa S, Shimozawa N et al. Hepatic resection for hepatocellular carcinoma in the elderly. J Am Coll Surg 2001;192:38-46.
    • (2001) J Am Coll Surg , vol.192 , pp. 38-46
    • Hanazaki, K.1    Kajikawa, S.2    Shimozawa, N.3
  • 33
    • 77749317233 scopus 로고    scopus 로고
    • Treatments for hepatocellular carcinoma in elderly patients are as effective as in younger patients: A 20- year multicentre experience
    • Mirici-Cappa F, Gramenzi A, Santi V et al. Treatments for hepatocellular carcinoma in elderly patients are as effective as in younger patients: a 20- year multicentre experience. Gut 2010;59:387-396.
    • (2010) Gut , vol.59 , pp. 387-396
    • Mirici-Cappa, F.1    Gramenzi, A.2    Santi, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.