-
1
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
15189148 10.1146/annurev.biochem.73.011303.073651 1:CAS:528: DC%2BD2cXmslags7c%3D
-
Blander G, Guarente L. The Sir2 family of protein deacetylases. Annu Rev Biochem. 2004;73:417-35.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
2
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
10693811 10.1038/35001622 1:CAS:528:DC%2BD3cXhsVWiurY%3D
-
Imai S, Armstrong CM, Kaeberlein M, et al. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature. 2000;403(6771):795-800.
-
(2000)
Nature
, vol.403
, Issue.6771
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
-
3
-
-
33644875936
-
Cloning, chromosomal characterization and mapping of the NAD-dependent histone deacetylases gene sirtuin 1
-
16328012 1:CAS:528:DC%2BD28XntlajsA%3D%3D
-
Voelter-Mahlknecht S, Mahlknecht U. Cloning, chromosomal characterization and mapping of the NAD-dependent histone deacetylases gene sirtuin 1. Int J Mol Med. 2006;17(1):59-67.
-
(2006)
Int J Mol Med
, vol.17
, Issue.1
, pp. 59-67
-
-
Voelter-Mahlknecht, S.1
Mahlknecht, U.2
-
4
-
-
0035913903
-
HSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
11672523 10.1016/S0092-8674(01)00527-X 1:CAS:528:DC%2BD3MXotVSntrs%3D
-
Vaziri H, Dessain SK, Ng EE, et al. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell. 2001;107(2):149-59.
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng, E.E.3
-
5
-
-
0034676439
-
Deacetylation of p53 modulates its effect on cell growth and apoptosis
-
11099047 10.1038/35042612 1:CAS:528:DC%2BD3cXosVertbg%3D
-
Luo J, Su F, Chen D, et al. Deacetylation of p53 modulates its effect on cell growth and apoptosis. Nature. 2000;408(6810):377-81.
-
(2000)
Nature
, vol.408
, Issue.6810
, pp. 377-381
-
-
Luo, J.1
Su, F.2
Chen, D.3
-
6
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
14980222 10.1016/S0092-8674(04)00126-6 1:CAS:528:DC%2BD2cXhvVKru7s%3D
-
Motta MC, Divecha N, Lemieux M, et al. Mammalian SIRT1 represses forkhead transcription factors. Cell. 2004;116(4):551-63.
-
(2004)
Cell
, vol.116
, Issue.4
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
-
7
-
-
12144286529
-
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis
-
15023334 10.1016/S1097-2765(04)00094-2 1:CAS:528:DC%2BD2cXis1Kktbs%3D
-
Cohen HY, Lavu S, Bitterman KJ, et al. Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis. Mol Cell. 2004;13(5):627-38.
-
(2004)
Mol Cell
, vol.13
, Issue.5
, pp. 627-638
-
-
Cohen, H.Y.1
Lavu, S.2
Bitterman, K.J.3
-
8
-
-
63249112836
-
Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway
-
19008341 10.2337/db07-1795 1:CAS:528:DC%2BD1MXhslersLc%3D
-
Lee JH, Song MY, Song EK, et al. Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway. Diabetes. 2009;58(2):344-51.
-
(2009)
Diabetes
, vol.58
, Issue.2
, pp. 344-351
-
-
Lee, J.H.1
Song, M.Y.2
Song, E.K.3
-
9
-
-
0037093346
-
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
-
12006491 10.1093/emboj/21.10.2383 1:CAS:528:DC%2BD38XktFChu7c%3D
-
Langley E, Pearson M, Faretta M, et al. Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J. 2002;21(10):2383-96.
-
(2002)
EMBO J
, vol.21
, Issue.10
, pp. 2383-2396
-
-
Langley, E.1
Pearson, M.2
Faretta, M.3
-
10
-
-
63649125404
-
Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition?
-
19075016 10.1074/jbc.M807869200 1:CAS:528:DC%2BD1MXht1Oru74%3D
-
Jung-Hynes B, Nihal M, Zhong W, et al. Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition? J Biol Chem. 2009;284(6):3823-32.
-
(2009)
J Biol Chem
, vol.284
, Issue.6
, pp. 3823-3832
-
-
Jung-Hynes, B.1
Nihal, M.2
Zhong, W.3
-
11
-
-
67650348173
-
Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma
-
19509139 10.1158/1078-0432.CCR-08-3329 1:CAS:528:DC%2BD1MXnvFajt74%3D
-
Cha EJ, Noh SJ, Kwon KS, et al. Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma. Clin Cancer Res. 2009;15(13):4453-9.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.13
, pp. 4453-4459
-
-
Cha, E.J.1
Noh, S.J.2
Kwon, K.S.3
-
12
-
-
68849097673
-
Expression and prognostic significance of SIRT1 in ovarian epithelial tumours
-
19404850 10.1080/00313020902884451 1:CAS:528:DC%2BD1MXltlSitLg%3D
-
Jang KY, Kim KS, Hwang SH, et al. Expression and prognostic significance of SIRT1 in ovarian epithelial tumours. Pathology. 2009;41(4):366-71.
-
(2009)
Pathology.
, vol.41
, Issue.4
, pp. 366-371
-
-
Jang, K.Y.1
Kim, K.S.2
Hwang, S.H.3
-
13
-
-
79958185807
-
Expression and role of SIRT1 in hepatocellular carcinoma
-
21567102 1:CAS:528:DC%2BC3MXpvVegtLs%3D
-
Choi HN, Bae JS, Jamiyandorj U, et al. Expression and role of SIRT1 in hepatocellular carcinoma. Oncol Rep. 2011;26(2):503-10.
-
(2011)
Oncol Rep
, vol.26
, Issue.2
, pp. 503-510
-
-
Choi, H.N.1
Bae, J.S.2
Jamiyandorj, U.3
-
14
-
-
53449083751
-
SIRT1 expression is associated with poor prognosis of diffuse large B-cell lymphoma
-
18724249 10.1097/PAS.0b013e31816b6478
-
Jang KY, Hwang SH, Kwon KS, et al. SIRT1 expression is associated with poor prognosis of diffuse large B-cell lymphoma. Am J Surg Pathol. 2008;32(10):1523-31.
-
(2008)
Am J Surg Pathol
, vol.32
, Issue.10
, pp. 1523-1531
-
-
Jang, K.Y.1
Hwang, S.H.2
Kwon, K.S.3
-
15
-
-
81355164576
-
Breast cancer statistics, 2011
-
21969133 10.3322/caac.20134
-
DeSantis C, Siegel R, Bandi P, et al. Breast cancer statistics, 2011. CA Cancer J Clin. 2011;61(6):409-18.
-
(2011)
CA Cancer J Clin
, vol.61
, Issue.6
, pp. 409-418
-
-
Desantis, C.1
Siegel, R.2
Bandi, P.3
-
16
-
-
33744960226
-
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
-
16757721 10.1001/jama.295.21.2492 1:CAS:528:DC%2BD28XlsV2rtLw%3D
-
Carey LA, Perou CM, Livasy CA, et al. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA. 2006;295(21):2492-502.
-
(2006)
JAMA
, vol.295
, Issue.21
, pp. 2492-2502
-
-
Carey, L.A.1
Perou, C.M.2
Livasy, C.A.3
-
17
-
-
33847063053
-
The triple negative paradox: Primary tumor chemosensitivity of breast cancer subtypes
-
17438091 10.1158/1078-0432.CCR-06-1109 1:CAS:528:DC%2BD2sXkt1enur0%3D
-
Carey LA, Dees EC, Sawyer L, et al. The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. Clin Cancer Res. 2007;13(8):2329-34.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.8
, pp. 2329-2334
-
-
Carey, L.A.1
Dees, E.C.2
Sawyer, L.3
-
18
-
-
0034680102
-
Molecular portraits of human breast tumours
-
10963602 10.1038/35021093 1:CAS:528:DC%2BD3cXmt1CnsLw%3D
-
Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature. 2000;406(6797):747-52.
-
(2000)
Nature
, vol.406
, Issue.6797
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
19
-
-
4143150688
-
Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma
-
15328174 10.1158/1078-0432.CCR-04-0220 1:CAS:528:DC%2BD2cXmvFSlt7k%3D
-
Nielsen TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res. 2004;10(16):5367-74.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.16
, pp. 5367-5374
-
-
Nielsen, T.O.1
Hsu, F.D.2
Jensen, K.3
-
20
-
-
33845215486
-
Basal phenotype identifies a poor prognostic subgroup of breast cancer of clinical importance
-
17055256 10.1016/j.ejca.2006.08.015 1:CAS:528:DC%2BD28Xht12rtrzK
-
Rakha EA, El-Rehim DA, Paish C, et al. Basal phenotype identifies a poor prognostic subgroup of breast cancer of clinical importance. Eur J Cancer. 2006;42(18):3149-56.
-
(2006)
Eur J Cancer
, vol.42
, Issue.18
, pp. 3149-3156
-
-
Rakha, E.A.1
El-Rehim, D.A.2
Paish, C.3
-
21
-
-
77954647009
-
Balance between SIRT1 and DBC1 expression is lost in breast cancer
-
20412117 10.1111/j.1349-7006.2010.01573.x 1:CAS:528:DC%2BC3cXpt1equ7c%3D
-
Sung JY, Kim R, Kim JE, et al. Balance between SIRT1 and DBC1 expression is lost in breast cancer. Cancer Sci. 2010;101(7):1738-44.
-
(2010)
Cancer Sci
, vol.101
, Issue.7
, pp. 1738-1744
-
-
Sung, J.Y.1
Kim, R.2
Kim, J.E.3
-
22
-
-
78751567751
-
Expression of DBC1 and SIRT1 is associated with poor prognosis for breast carcinoma
-
21056897 10.1016/j.humpath.2010.05.023 1:CAS:528:DC%2BC3MXmsFaktw%3D%3D
-
Lee H, Kim KR, Noh SJ, et al. Expression of DBC1 and SIRT1 is associated with poor prognosis for breast carcinoma. Hum Pathol. 2011;42(2):204-13.
-
(2011)
Hum Pathol
, vol.42
, Issue.2
, pp. 204-213
-
-
Lee, H.1
Kim, K.R.2
Noh, S.J.3
-
25
-
-
0027143621
-
Overexpression of p53 and prognosis in breast cancer
-
8252480 10.1002/1097-0142(19931215)72:12<3641: AID- CNCR2820721215>3.0.CO;2-8 1:STN:280:DyaK2c%2Fntlyjug%3D%3D
-
Friedrichs K, Gluba S, Eidtmann H, et al. Overexpression of p53 and prognosis in breast cancer. Cancer. 1993;72(12):3641-7.
-
(1993)
Cancer
, vol.72
, Issue.12
, pp. 3641-3647
-
-
Friedrichs, K.1
Gluba, S.2
Eidtmann, H.3
-
26
-
-
33646886778
-
Comprehensive analysis of HE4 expression in normal and malignant human tissues
-
16607372 1:CAS:528:DC%2BD28Xkslels70%3D
-
Galgano MT, Hampton GM, Frierson HJ. Comprehensive analysis of HE4 expression in normal and malignant human tissues. Mod Pathol. 2006;19(6):847-53.
-
(2006)
Mod Pathol
, vol.19
, Issue.6
, pp. 847-853
-
-
Galgano, M.T.1
Hampton, G.M.2
Frierson, H.J.3
-
27
-
-
44849096876
-
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth
-
18414679 10.1371/journal.pone.0002020
-
Firestein R, Blander G, Michan S, et al. The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. PLoS ONE. 2008;3(4):e2020.
-
(2008)
PLoS ONE
, vol.3
, Issue.4
, pp. 2020
-
-
Firestein, R.1
Blander, G.2
Michan, S.3
-
28
-
-
34547451766
-
Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor
-
17505061 10.1210/me.2006-0467 1:CAS:528:DC%2BD2sXos12rsr4%3D
-
Dai Y, Ngo D, Forman LW, et al. Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor. Mol Endocrinol. 2007;21(8):1807-21.
-
(2007)
Mol Endocrinol
, vol.21
, Issue.8
, pp. 1807-1821
-
-
Dai, Y.1
Ngo, D.2
Forman, L.W.3
-
29
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
15152190 10.1038/sj.emboj.7600244 1:CAS:528:DC%2BD2cXkvVeku7Y%3D
-
Yeung F, Hoberg JE, Ramsey CS, et al. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 2004;23(12):2369-80.
-
(2004)
EMBO J
, vol.23
, Issue.12
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
-
30
-
-
0034676455
-
Surfing the p53 network
-
11099028 10.1038/35042675 1:CAS:528:DC%2BD3cXosVemtrY%3D
-
Vogelstein B, Lane D, Levine AJ. Surfing the p53 network. Nature. 2000;408(6810):307-10.
-
(2000)
Nature
, vol.408
, Issue.6810
, pp. 307-310
-
-
Vogelstein, B.1
Lane, D.2
Levine, A.J.3
-
31
-
-
0034594895
-
P53 sends nucleotides to repair DNA
-
10716425 10.1038/35003670 1:CAS:528:DC%2BD3cXhvVymtb8%3D
-
Lozano G, Elledge SJ. p53 sends nucleotides to repair DNA. Nature. 2000;404(6773):24-5.
-
(2000)
Nature
, vol.404
, Issue.6773
, pp. 24-25
-
-
Lozano, G.1
Elledge, S.J.2
-
32
-
-
0028568440
-
Association of immunohistochemical p53 tumor suppressor gene protein overexpression with prognosis in highly proliferative human mammary adenocarcinomas
-
832-33
-
Schimmelpenning H, Eriksson ET, Zetterberg A, et al. Association of immunohistochemical p53 tumor suppressor gene protein overexpression with prognosis in highly proliferative human mammary adenocarcinomas. World J Surg. 1994;18(6):827-32, 832-33.
-
(1994)
World J Surg.
, vol.18
, Issue.6
, pp. 827-832
-
-
Schimmelpenning, H.1
Eriksson, E.T.2
Zetterberg, A.3
-
33
-
-
0028417998
-
The association of p53 immunopositivity with tumor proliferation and other prognostic indicators in breast cancer
-
8058709 1:STN:280:DyaK2czjs1Khuw%3D%3D
-
Bhargava V, Thor A, Deng G, et al. The association of p53 immunopositivity with tumor proliferation and other prognostic indicators in breast cancer. Mod Pathol. 1994;7(3):361-8.
-
(1994)
Mod Pathol
, vol.7
, Issue.3
, pp. 361-368
-
-
Bhargava, V.1
Thor, A.2
Deng, G.3
-
34
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
11672522 10.1016/S0092-8674(01)00524-4 1:CAS:528:DC%2BD3MXotVSntro%3D
-
Luo J, Nikolaev AY, Imai S, et al. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell. 2001;107(2):137-48.
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
-
35
-
-
34247547120
-
Human SIRT1: A potential biomarker for tumorigenesis?
-
17433727 10.1016/j.cellbi.2006.11.003 1:CAS:528:DC%2BD2sXkvFGrtbk%3D
-
Lim CS. Human SIRT1: a potential biomarker for tumorigenesis? Cell Biol Int. 2007;31(6):636-7.
-
(2007)
Cell Biol Int
, vol.31
, Issue.6
, pp. 636-637
-
-
Lim, C.S.1
-
36
-
-
27544434763
-
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
-
16269335 10.1016/j.cell.2005.08.011 1:CAS:528:DC%2BD2MXht1altLnJ
-
Chen WY, Wang DH, Yen RC, et al. Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell. 2005;123(3):437-48.
-
(2005)
Cell
, vol.123
, Issue.3
, pp. 437-448
-
-
Chen, W.Y.1
Wang, D.H.2
Yen, R.C.3
-
37
-
-
0141814680
-
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
-
12960381 10.1073/pnas.1934713100 1:CAS:528:DC%2BD3sXnslyntrc%3D
-
Cheng HL, Mostoslavsky R, Saito S, et al. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci USA. 2003;100(19):10794-9.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.19
, pp. 10794-10799
-
-
Cheng, H.L.1
Mostoslavsky, R.2
Saito, S.3
-
38
-
-
70249123890
-
Biology, metastatic patterns, and treatment of patients with triple-negative breast cancer
-
19596646 10.3816/CBC.2009.s.008 1:CAS:528:DC%2BD1MXptlWgt7w%3D
-
Anders CK, Carey LA. Biology, metastatic patterns, and treatment of patients with triple-negative breast cancer. Clin Breast Cancer. 2009;9(Suppl 2):S73-81.
-
(2009)
Clin Breast Cancer
, vol.9
, Issue.SUPPL. 2
-
-
Anders, C.K.1
Carey, L.A.2
-
39
-
-
70449645182
-
T1N0 triple negative breast cancer: Risk of recurrence and adjuvant chemotherapy
-
19671105 10.1111/j.1524-4741.2009.00789.x
-
Kaplan HG, Malmgren JA, Atwood M. T1N0 triple negative breast cancer: risk of recurrence and adjuvant chemotherapy. Breast J. 2009;15(5):454-60.
-
(2009)
Breast J
, vol.15
, Issue.5
, pp. 454-460
-
-
Kaplan, H.G.1
Malmgren, J.A.2
Atwood, M.3
-
40
-
-
51349102645
-
Impact of triple negative phenotype on breast cancer prognosis
-
18657139 10.1111/j.1524-4741.2008.00622.x
-
Kaplan HG, Malmgren JA. Impact of triple negative phenotype on breast cancer prognosis. Breast J. 2008;14(5):456-63.
-
(2008)
Breast J
, vol.14
, Issue.5
, pp. 456-463
-
-
Kaplan, H.G.1
Malmgren, J.A.2
-
41
-
-
33747819585
-
Clinicopathologic significance of the basal-like subtype of breast cancer: A comparison with hormone receptor and Her2/neu-overexpressing phenotypes
-
16938528 10.1016/j.humpath.2006.04.015 1:CAS:528:DC%2BD28XovVWrt7k%3D
-
Kim MJ, Ro JY, Ahn SH, et al. Clinicopathologic significance of the basal-like subtype of breast cancer: a comparison with hormone receptor and Her2/neu-overexpressing phenotypes. Hum Pathol. 2006;37(9):1217-26.
-
(2006)
Hum Pathol
, vol.37
, Issue.9
, pp. 1217-1226
-
-
Kim, M.J.1
Ro, J.Y.2
Ahn, S.H.3
-
42
-
-
45149094267
-
Basal-like breast cancer: A critical review
-
18487574 10.1200/JCO.2007.13.1748
-
Rakha EA, Reis-Filho JS, Ellis IO. Basal-like breast cancer: a critical review. J Clin Oncol. 2008;26(15):2568-81.
-
(2008)
J Clin Oncol
, vol.26
, Issue.15
, pp. 2568-2581
-
-
Rakha, E.A.1
Reis-Filho, J.S.2
Ellis, I.O.3
|