Microwave-Assisted synthesis of 30-indolyl substituted 4H-chromenes catalyzed by DMAP and their antimicrobial activity

Medicinal Chemistry Research

Volumn 21, Issue 11, 2012, Pages 3406-3416

  Kathrotiya, Harshad G ^a   Patel, Manish P ^a  

^a SARDAR PATEL UNIVERSITY   (India)

Author keywords

4H Chromene; DMAP; In vitro antimicrobial activity; Indole; MCR; Microwave irradiation

Indexed keywords

2 AMINO 4 [2 (4 BROMOPHENYL) 1H INDOL 3 YL] 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 4 [2 (4 BROMOPHENYL) 1H INDOL 3 YL] 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 4 [2 (4 CHLOROPHENYL) 1H INDOL 3 YL] 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 4 [2 (4 CHLOROPHENYL) 1H INDOL 3 YL] 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 4 [2 (4 FLUOROPHENYL) 1H INDOL 3 YL] 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 4 [2 (4 FLUOROPHENYL) 1H INDOL 3 YL] 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 4 [2 (4 METHOXYPHENYL) 1H INDOL 3 YL] 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 4 [2 (4 METHOXYPHENYL) 1H INDOL 3 YL] 7,7 DIMETHYL 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 4 [2 (4 NITROPHENYL) 1H INDOL 3 YL] 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 4 [2 [4 (METHYLSULFONYL)PHENYL) 1H INDOL 3 YL]] 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 5 OXO 4 (2 PHENYL 1H INDOL 3 YL) 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 5 OXO 4 [2 (4 METHYLPHENYL) 1H INDOL 3 YL] 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 7,7 DIMETHYL 4 [2 (4 NITROPHENYL) 1H INDOL 3 YL] 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 7,7 DIMETHYL 5 OXO 4 (2 PHENYL 1H INDOL 3 YL) 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 7,7 DIMETHYL 5 OXO 4 [2 (4 METHYLPHENYL) 1H INDOL 3 YL] 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; 2 AMINO 7,7 DIMETHYL-4 [2 [4 (METHYLSULFONYL)PHENYL] 1H INDOL 3 YL] 5 OXO 5,6,7,8 TETRAHYDRO 4H CHROMENE 3 CARBONITRILE; CHROMENE DERIVATIVE; INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; CYCLIZATION; DRUG SYNTHESIS; MICHAEL ADDITION; MICROWAVE IRRADIATION; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR WEIGHT; NONHUMAN; REACTION TIME; STRUCTURE ACTIVITY RELATION;

EID: 84871252293     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-011-9861-4     Document Type: Article

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